Eray Aksoy - Academia.edu (original) (raw)
Papers by Eray Aksoy
Journal of Cardiac Surgery, Dec 20, 2015
Depression and mood disorders occur commonly following emergent cardiac surgery. Selective seroto... more Depression and mood disorders occur commonly following emergent cardiac surgery. Selective serotonin reuptake inhibitors are commonly used antidepressants. We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners, Oct 28, 2013
Background: The surgical approach for effusive constrictive pericarditis (ECP) has not been exten... more Background: The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. Methods: Diagnosis was made primarily by echocardiography. Right heart catheterisation was performed in eight patients. Pre-operatively, 10 patients had undergone at least one previous attempt at therapeutic pericardiocentesis. Pericardiectomy was performed where appropriate (thickened or inflamed). Results: Of our 12 patients (50% male, median age 48 years, range 17-72 years), the underlying aetiology included idiopathic in five (41.6%), tuberculosis in four (33%), and malignancy in three patients (25%). Elective surgery was performed in nine patients. Median values of both central venous pressure and pulmonary capillary wedge pressure decreased markedly postoperatively (from 16.5 to 11.0 mmHg, p = 0.02; 20.0-15.0 mmHg, p = 0.01, respectively). There was no in-hospital mortality. Follow up ranged from three months to nine years (median three years). Five (41.6%) patients died during the follow-up period, and cumulative two-year survival was 55.6 ± 1.5%. Conclusion: Pericardiectomy for ECP was effective, in terms of our early results, in patients unresponsive to medical therapy. Long-term survival depends on the underlying disease.
Asian Cardiovascular and Thoracic Annals, Oct 9, 2013
Objective: To share our results of a case series of 8 patients who underwent pericardiectomy for ... more Objective: To share our results of a case series of 8 patients who underwent pericardiectomy for constrictive pericarditis that developed secondary to a known neoplastic disease. Patients and methods: The underlying neoplasia was lung cancer in 5 (62.5%) patients, malignant pleural mesothelioma in 2 (25%), and Hodgkin lymphoma in 1 (12.5%). A diagnosis of constrictive pericarditis was made primarily by echocardiography, and right heart catheterization was performed in 6 (75%) patients. Total pericardiectomy was defined as wide excision of the anterior pericardium. Follow-up information was obtained by telephone interview and the civil registry database. Results: Time from initial diagnosis of the neoplastic disease ranged from 1 to 15 years. Total pericardiectomy was performed in 6 (75%) patients. Histopathological examination revealed atypical cells in evacuated fluid and pericardial material in 6 patients. Nonspecific inflammation and fibrosis were observed in the other 2 cases. Hospital death occurred in 1 (12.5%) patient. Postoperative low cardiac output syndrome occurred in 7 (87.5%) patients. Follow-up ranged from 2.92 to 26.78 months. Mean survival was 14.82 AE 4.4 months. Conclusion: Pericardial constriction may develop a long time after the initial presentation of certain neoplastic diseases, and the prognosis after pericardiectomy is poor.
Polish Journal of Thoracic and Cardiovascular Surgery, 2013
Aortic valve prolapse (AVP) in patients with a ventricular septal defect (VSD) is known to be cau... more Aortic valve prolapse (AVP) in patients with a ventricular septal defect (VSD) is known to be caused by high gradient flow through the defect. In adult patients, VSD may lead to AVP and subsequent aortic regurgitation (AR). Although aortic valvuloplasty and the concurrent closure of the defect is the therapy of choice for children, it carries a high risk of reoperation in adults. We present a case of a 20-year-old male with perimembranous outlet type VSD and severe AR. During the operation, the non-coronary cusp was inverted towards the defect and used as an in situ patch. The severely deformed coronary cusps were excised and the aortic valve was replaced.
European Heart Journal, Jul 1, 1997
International Journal of Cardiology, Mar 1, 2013
Age 60.2±9.7 58.8±12.1 0.665 Sex (%) 26 (72.2) 84 (77.1) 0.556 Diabetes mellitus (%) 8 (22.2) 19 ... more Age 60.2±9.7 58.8±12.1 0.665 Sex (%) 26 (72.2) 84 (77.1) 0.556 Diabetes mellitus (%) 8 (22.2) 19 (17.4) 0.522 Culprit vessel LAD 47 (43.1) 16 (44.4) Cx 13 (11.9) 4 (11.1) RCA 49 (44.9) 16 (44.4) Initial cTFC 91.2±21.5 92.1±19.7 0.938 Initial TIMI flow 0.5±1.0 0.50±0.8 0.456 Final cTFC 27.2±15.9 37.0±25.5 0.038 Final TIMI flow 2.7±0.4 2.5±0.7 0.062 Severe Noreflow (%) 0 10 (9.1) 0.059 DcTFC 64.1±29.8 55.1±31.4 0.041
International Journal of Cardiology, Mar 1, 2013
Journal of Electrocardiology, Jul 1, 2013
Aim of this study was to investigate the prognostic significance of absence of septal Q waves in ... more Aim of this study was to investigate the prognostic significance of absence of septal Q waves in patients scheduled for aortic valve replacement. Sixty-one patients who underwent isolated aortic valve replacement for aortic stenosis were retrospectively evaluated. Septal Q waves were defined as Q waves of<2mm in amplitude and<40ms in width and absence of septal Q waves was defined as simultaneous loss of Q waves from at least three of the leads I, aVL, V5 and V6. Septal Q waves were absent in 17 patients (Group AQ, 27.8%) and were present in 44 patients (Group PQ, 72.1 %) preoperatively. Newly developed AV block>1st degree and newly developed left bundle branch block were primary endpoints. Preoperatively, absence of normal septal Q waves was significantly associated with increased risk of postoperative AV block (HR: 11.18, range 1.37-91.21, 95% CI, p=0.02) whereas it was not associated with increased risk for newly developed LBBB (HR: 3.15 0.62-15.83, 95% CI, p=0.16). Absence of normal septal Q waves in the preoperative ECG may predict further delay in conduction which might develop in the early postoperative course of aortic valve replacement.
Kosuyolu Heart Journal, 2015
Introduction: Less-invasive procedures have gained more widespread adoption among cardiovascular ... more Introduction: Less-invasive procedures have gained more widespread adoption among cardiovascular surgeons as a result of continuous advances in the fi eld of cardiac surgical techniques. It has now become clear that even smaller incisions may provide adequate exposure in certain cardiac surgical procedures without compromising the surgeon's view of the surgical fi eld. Furthermore, a limited incision offers the advantage of cosmetic outcomes, hence an improved quality-of-life after the operation. Herein, we report our experience regarding the use of partial upper sternotomy with limited skin incision for isolated or combined aortic valve operations. Patients and Methods: A total of 34 patients underwent aortic valve surgery via partial J-shaped upper sternotomy in two separate centers between January 2013 and December 2014. Sixteen patients (47%) underwent an isolated aortic valve replacement, while 18 patients (53%) underwent a modifi ed Bentall procedure. Descriptive data included demographic and clinical outcome parameters. Results: Mean age was 54 ± 14 years (range: 19 to 82 years) and there were 11 females (32%). The average duration of surgery was 6.8 ± 1.8 hours, ranging from 4 to 10 hours. Early mortality occurred in 1 patient. Two patients had wound infection and they were re-hospitalized for wound care. Conclusion: Our preliminary result regarding the use of partial upper ministernotomy is encouraging. The technique allows adequate exposure during aortic valve surgery, even in procedures involving the proximal ascending aorta. Further studies are warranted to test the safety and effi cacy of this approach.
Vascular, 2016
Aim This pilot study aimed to reveal whether combination of electrostimulation with iloprost trea... more Aim This pilot study aimed to reveal whether combination of electrostimulation with iloprost treatment achieves better results compared to iloprost alone in patients with critical limb ischemia. Material and methods Patients were randomized into Group 1 ( n = 11, mean age: 65.3 ± 4.2 years, received iloprost infusion protocol alone) or Group 2 ( n = 11, mean age: 62.9 ± 6.7, received iloprost infusion plus standardized protocol of peroneal nerve electrostimulation). Electrostimulation was delivered with 1 Hz frequency, 27 mA current, and 200 ms pulse width. Peak blood flow velocities in the anterior and posterior tibialis arteries were measured with duplex ultrasound. Results There was a slight insignificant increase in blood velocity in anterior tibialis artery in Group 1 (from 17.6 ± 13.0 to 18.6 ± 13.1, p = 0.57), whereas the increase in Group 2 was marked (from 23.8 ± 18.3 to 32.2 ± 19.7, p = 0.01). Blood velocity in posterior tibialis artery also increased in both groups, but i...
Indian Journal of Nephrology, 2016
Despite its high success rate for long-term hemodialysis access, AVFs tend to be complicated by f... more Despite its high success rate for long-term hemodialysis access, AVFs tend to be complicated by flow derangements. The long-term patency of a native AVF has been of concern since patency was linked to patient survival. [2] Stenosis or occlusion are major problems that have increasingly been treated by percutaneous catheter-based interventions. [3] On the other hand, high access flows may cause diffuse aneurysmal degeneration, steal syndrome, hand ischemia or cardiac overload. [4,5]
Turkiye Klinikleri Cardiovascular Sciences, 2012
Acta Angiologica, 2016
Introduction. Risk of failure after surgical creation of the AVF was linked to the diameter and f... more Introduction. Risk of failure after surgical creation of the AVF was linked to the diameter and flow dynamics of the vessel that is to be quantified by preoperative ultrasound mapping. We aimed to report our results using a different technique consisting of Fogarty ® catheter dilatation of the cephalic vein after completion of the anastomosis. Material and methods. A total of 23 patients, aged between 35 to 70 years, with a cephalic vein diameter of ≤ 2.5 mm received a dilatation technique for arteriovenous creation. Patients having reoperations, aneurysmatic or thrombosed veins and multiple risk factors were not considered eligible and access failure within 60 days was defined as early fistula failure. Results. Mean cephalic vein diameter was 2.03 ± 0.28 mm and mean radial artery diameter was 2.33 ± 0.16 mm. At 15 th day visit, 21 of 23 patients (91.3%) had patent arteriovenous fistula. Mean time of follow-up was 7.2 ± 1.67 months and was complete in 20 of 21 patients with a patent fistula. Overall patency was 18/23 (78.2%) in patients with survived AVFs. Conclusion. Fogarty ® catheter dilatation of the cephalic vein after completion of the anastomosis during arteriovenous fistula creation is effective and safe in patients with small calibrated veins.
Damar Cerrahi Dergisi, 2015
Bratislava Medical Journal, 2012
Background: Hepatic artery aneurysm (HAA) is a rare clinical entity that can lead to potentially ... more Background: Hepatic artery aneurysm (HAA) is a rare clinical entity that can lead to potentially life threatening complications. We reported our personal experience of 4 cases, in which we used different procedures. Methods: The fi rst case had a pseudo-aneurysm involving the right hepatic artery. The second case had a pseudoaneurysm, which was localized distal to the accidentally ligated right hepatic artery from the previous cholecystectomy operation. The third case had multiple aneurysms with accompanying dissecting abdominal aortic aneurysm. The fourth case had a pseudo-aneurysm originating from the proper hepatic artery. A covered stent was successfully placed in the case 1. In the second case, the right hepatic artery was ligated distal to the aneurysm. In the third case, vascular structures were not appropriate for vascular reconstruction, and a covered stent placement and embolization were unsuccessful. In the fourth case, ligation of the proper hepatic artery and cholecystectomy was performed. Results: The third case with multiple aneurysms died from multi-organ failure due to sepsis. The remaining cases (case 1, 2, and 4) are disease free and alive. Conclusion: HAAs are more commonly observed clinical entities, and their treatment should be handled for each patient separately. Computerized tomography-Angiography and intraoperative Doppler ultrasound are useful radio-diagnostics for determination of aneurysm and planning the operative procedure (Fig. 5, Ref. 15).
International Journal of Cardiology, 2013
International Journal of Cardiology, 2013
Journal of Cardiac Surgery, Dec 20, 2015
Depression and mood disorders occur commonly following emergent cardiac surgery. Selective seroto... more Depression and mood disorders occur commonly following emergent cardiac surgery. Selective serotonin reuptake inhibitors are commonly used antidepressants. We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners, Oct 28, 2013
Background: The surgical approach for effusive constrictive pericarditis (ECP) has not been exten... more Background: The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. Methods: Diagnosis was made primarily by echocardiography. Right heart catheterisation was performed in eight patients. Pre-operatively, 10 patients had undergone at least one previous attempt at therapeutic pericardiocentesis. Pericardiectomy was performed where appropriate (thickened or inflamed). Results: Of our 12 patients (50% male, median age 48 years, range 17-72 years), the underlying aetiology included idiopathic in five (41.6%), tuberculosis in four (33%), and malignancy in three patients (25%). Elective surgery was performed in nine patients. Median values of both central venous pressure and pulmonary capillary wedge pressure decreased markedly postoperatively (from 16.5 to 11.0 mmHg, p = 0.02; 20.0-15.0 mmHg, p = 0.01, respectively). There was no in-hospital mortality. Follow up ranged from three months to nine years (median three years). Five (41.6%) patients died during the follow-up period, and cumulative two-year survival was 55.6 ± 1.5%. Conclusion: Pericardiectomy for ECP was effective, in terms of our early results, in patients unresponsive to medical therapy. Long-term survival depends on the underlying disease.
Asian Cardiovascular and Thoracic Annals, Oct 9, 2013
Objective: To share our results of a case series of 8 patients who underwent pericardiectomy for ... more Objective: To share our results of a case series of 8 patients who underwent pericardiectomy for constrictive pericarditis that developed secondary to a known neoplastic disease. Patients and methods: The underlying neoplasia was lung cancer in 5 (62.5%) patients, malignant pleural mesothelioma in 2 (25%), and Hodgkin lymphoma in 1 (12.5%). A diagnosis of constrictive pericarditis was made primarily by echocardiography, and right heart catheterization was performed in 6 (75%) patients. Total pericardiectomy was defined as wide excision of the anterior pericardium. Follow-up information was obtained by telephone interview and the civil registry database. Results: Time from initial diagnosis of the neoplastic disease ranged from 1 to 15 years. Total pericardiectomy was performed in 6 (75%) patients. Histopathological examination revealed atypical cells in evacuated fluid and pericardial material in 6 patients. Nonspecific inflammation and fibrosis were observed in the other 2 cases. Hospital death occurred in 1 (12.5%) patient. Postoperative low cardiac output syndrome occurred in 7 (87.5%) patients. Follow-up ranged from 2.92 to 26.78 months. Mean survival was 14.82 AE 4.4 months. Conclusion: Pericardial constriction may develop a long time after the initial presentation of certain neoplastic diseases, and the prognosis after pericardiectomy is poor.
Polish Journal of Thoracic and Cardiovascular Surgery, 2013
Aortic valve prolapse (AVP) in patients with a ventricular septal defect (VSD) is known to be cau... more Aortic valve prolapse (AVP) in patients with a ventricular septal defect (VSD) is known to be caused by high gradient flow through the defect. In adult patients, VSD may lead to AVP and subsequent aortic regurgitation (AR). Although aortic valvuloplasty and the concurrent closure of the defect is the therapy of choice for children, it carries a high risk of reoperation in adults. We present a case of a 20-year-old male with perimembranous outlet type VSD and severe AR. During the operation, the non-coronary cusp was inverted towards the defect and used as an in situ patch. The severely deformed coronary cusps were excised and the aortic valve was replaced.
European Heart Journal, Jul 1, 1997
International Journal of Cardiology, Mar 1, 2013
Age 60.2±9.7 58.8±12.1 0.665 Sex (%) 26 (72.2) 84 (77.1) 0.556 Diabetes mellitus (%) 8 (22.2) 19 ... more Age 60.2±9.7 58.8±12.1 0.665 Sex (%) 26 (72.2) 84 (77.1) 0.556 Diabetes mellitus (%) 8 (22.2) 19 (17.4) 0.522 Culprit vessel LAD 47 (43.1) 16 (44.4) Cx 13 (11.9) 4 (11.1) RCA 49 (44.9) 16 (44.4) Initial cTFC 91.2±21.5 92.1±19.7 0.938 Initial TIMI flow 0.5±1.0 0.50±0.8 0.456 Final cTFC 27.2±15.9 37.0±25.5 0.038 Final TIMI flow 2.7±0.4 2.5±0.7 0.062 Severe Noreflow (%) 0 10 (9.1) 0.059 DcTFC 64.1±29.8 55.1±31.4 0.041
International Journal of Cardiology, Mar 1, 2013
Journal of Electrocardiology, Jul 1, 2013
Aim of this study was to investigate the prognostic significance of absence of septal Q waves in ... more Aim of this study was to investigate the prognostic significance of absence of septal Q waves in patients scheduled for aortic valve replacement. Sixty-one patients who underwent isolated aortic valve replacement for aortic stenosis were retrospectively evaluated. Septal Q waves were defined as Q waves of<2mm in amplitude and<40ms in width and absence of septal Q waves was defined as simultaneous loss of Q waves from at least three of the leads I, aVL, V5 and V6. Septal Q waves were absent in 17 patients (Group AQ, 27.8%) and were present in 44 patients (Group PQ, 72.1 %) preoperatively. Newly developed AV block>1st degree and newly developed left bundle branch block were primary endpoints. Preoperatively, absence of normal septal Q waves was significantly associated with increased risk of postoperative AV block (HR: 11.18, range 1.37-91.21, 95% CI, p=0.02) whereas it was not associated with increased risk for newly developed LBBB (HR: 3.15 0.62-15.83, 95% CI, p=0.16). Absence of normal septal Q waves in the preoperative ECG may predict further delay in conduction which might develop in the early postoperative course of aortic valve replacement.
Kosuyolu Heart Journal, 2015
Introduction: Less-invasive procedures have gained more widespread adoption among cardiovascular ... more Introduction: Less-invasive procedures have gained more widespread adoption among cardiovascular surgeons as a result of continuous advances in the fi eld of cardiac surgical techniques. It has now become clear that even smaller incisions may provide adequate exposure in certain cardiac surgical procedures without compromising the surgeon's view of the surgical fi eld. Furthermore, a limited incision offers the advantage of cosmetic outcomes, hence an improved quality-of-life after the operation. Herein, we report our experience regarding the use of partial upper sternotomy with limited skin incision for isolated or combined aortic valve operations. Patients and Methods: A total of 34 patients underwent aortic valve surgery via partial J-shaped upper sternotomy in two separate centers between January 2013 and December 2014. Sixteen patients (47%) underwent an isolated aortic valve replacement, while 18 patients (53%) underwent a modifi ed Bentall procedure. Descriptive data included demographic and clinical outcome parameters. Results: Mean age was 54 ± 14 years (range: 19 to 82 years) and there were 11 females (32%). The average duration of surgery was 6.8 ± 1.8 hours, ranging from 4 to 10 hours. Early mortality occurred in 1 patient. Two patients had wound infection and they were re-hospitalized for wound care. Conclusion: Our preliminary result regarding the use of partial upper ministernotomy is encouraging. The technique allows adequate exposure during aortic valve surgery, even in procedures involving the proximal ascending aorta. Further studies are warranted to test the safety and effi cacy of this approach.
Vascular, 2016
Aim This pilot study aimed to reveal whether combination of electrostimulation with iloprost trea... more Aim This pilot study aimed to reveal whether combination of electrostimulation with iloprost treatment achieves better results compared to iloprost alone in patients with critical limb ischemia. Material and methods Patients were randomized into Group 1 ( n = 11, mean age: 65.3 ± 4.2 years, received iloprost infusion protocol alone) or Group 2 ( n = 11, mean age: 62.9 ± 6.7, received iloprost infusion plus standardized protocol of peroneal nerve electrostimulation). Electrostimulation was delivered with 1 Hz frequency, 27 mA current, and 200 ms pulse width. Peak blood flow velocities in the anterior and posterior tibialis arteries were measured with duplex ultrasound. Results There was a slight insignificant increase in blood velocity in anterior tibialis artery in Group 1 (from 17.6 ± 13.0 to 18.6 ± 13.1, p = 0.57), whereas the increase in Group 2 was marked (from 23.8 ± 18.3 to 32.2 ± 19.7, p = 0.01). Blood velocity in posterior tibialis artery also increased in both groups, but i...
Indian Journal of Nephrology, 2016
Despite its high success rate for long-term hemodialysis access, AVFs tend to be complicated by f... more Despite its high success rate for long-term hemodialysis access, AVFs tend to be complicated by flow derangements. The long-term patency of a native AVF has been of concern since patency was linked to patient survival. [2] Stenosis or occlusion are major problems that have increasingly been treated by percutaneous catheter-based interventions. [3] On the other hand, high access flows may cause diffuse aneurysmal degeneration, steal syndrome, hand ischemia or cardiac overload. [4,5]
Turkiye Klinikleri Cardiovascular Sciences, 2012
Acta Angiologica, 2016
Introduction. Risk of failure after surgical creation of the AVF was linked to the diameter and f... more Introduction. Risk of failure after surgical creation of the AVF was linked to the diameter and flow dynamics of the vessel that is to be quantified by preoperative ultrasound mapping. We aimed to report our results using a different technique consisting of Fogarty ® catheter dilatation of the cephalic vein after completion of the anastomosis. Material and methods. A total of 23 patients, aged between 35 to 70 years, with a cephalic vein diameter of ≤ 2.5 mm received a dilatation technique for arteriovenous creation. Patients having reoperations, aneurysmatic or thrombosed veins and multiple risk factors were not considered eligible and access failure within 60 days was defined as early fistula failure. Results. Mean cephalic vein diameter was 2.03 ± 0.28 mm and mean radial artery diameter was 2.33 ± 0.16 mm. At 15 th day visit, 21 of 23 patients (91.3%) had patent arteriovenous fistula. Mean time of follow-up was 7.2 ± 1.67 months and was complete in 20 of 21 patients with a patent fistula. Overall patency was 18/23 (78.2%) in patients with survived AVFs. Conclusion. Fogarty ® catheter dilatation of the cephalic vein after completion of the anastomosis during arteriovenous fistula creation is effective and safe in patients with small calibrated veins.
Damar Cerrahi Dergisi, 2015
Bratislava Medical Journal, 2012
Background: Hepatic artery aneurysm (HAA) is a rare clinical entity that can lead to potentially ... more Background: Hepatic artery aneurysm (HAA) is a rare clinical entity that can lead to potentially life threatening complications. We reported our personal experience of 4 cases, in which we used different procedures. Methods: The fi rst case had a pseudo-aneurysm involving the right hepatic artery. The second case had a pseudoaneurysm, which was localized distal to the accidentally ligated right hepatic artery from the previous cholecystectomy operation. The third case had multiple aneurysms with accompanying dissecting abdominal aortic aneurysm. The fourth case had a pseudo-aneurysm originating from the proper hepatic artery. A covered stent was successfully placed in the case 1. In the second case, the right hepatic artery was ligated distal to the aneurysm. In the third case, vascular structures were not appropriate for vascular reconstruction, and a covered stent placement and embolization were unsuccessful. In the fourth case, ligation of the proper hepatic artery and cholecystectomy was performed. Results: The third case with multiple aneurysms died from multi-organ failure due to sepsis. The remaining cases (case 1, 2, and 4) are disease free and alive. Conclusion: HAAs are more commonly observed clinical entities, and their treatment should be handled for each patient separately. Computerized tomography-Angiography and intraoperative Doppler ultrasound are useful radio-diagnostics for determination of aneurysm and planning the operative procedure (Fig. 5, Ref. 15).
International Journal of Cardiology, 2013
International Journal of Cardiology, 2013