Eric Garshick - Academia.edu (original) (raw)
Papers by Eric Garshick
American Journal of Physical Medicine & Rehabilitation, May 1, 2007
American Journal of Respiratory and Critical Care Medicine, Apr 1, 2008
Respiratory Medicine, Jul 1, 2012
Journal of Spinal Cord Medicine, Feb 9, 2018
Environmental Health Perspectives, Jul 1, 2006
PLOS ONE
This study investigated the associations between solar and geomagnetic activity and circulating b... more This study investigated the associations between solar and geomagnetic activity and circulating biomarkers of systemic inflammation and endothelial activation in the Normative Aging Study (NAS) cohort. Mixed effects models with moving day averages from day 0 to day 28 were used to study the associations between solar activity (sunspot number (SSN), interplanetary magnetic field (IMF)), geomagnetic activity (planetary K index (Kpindex), and various inflammatory and endothelial markers. Biomarkers included intracellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), C-reactive protein (CRP), and fibrinogen. After adjusting for demographic and meteorological variables, we observed significant positive associations between sICAM-1 and sVCAM-1 concentrations and solar and geomagnetic activity parameters: IMF, SSN, and Kp. Additionally, a negative association was observed between fibrinogen and Kpindex and a positive association was observed for CRP and SSN. T...
Journal of Exposure Science & Environmental Epidemiology, 2022
Environment International, 2020
Environmental Pollution, 2019
Environmental Research, 2019
Environmental Research, 2019
Environment International, 2019
Environmental Research Communications, 2019
Journal of thoracic disease, 2018
Oxidative stress is involved in thoracic diseases and health responses to air pollution. Malondia... more Oxidative stress is involved in thoracic diseases and health responses to air pollution. Malondialdehyde (MDA) is a well-established marker of oxidative stress, but it may be present in unconjugated and conjugated forms. To our knowledge, no studies have conducted a systemic evaluation of both free MDA (unconjugated MDA) and total MDA (the sum of both unconjugated and conjugated MDA) across various types of human biospecimens. Free MDA and total MDA were simultaneously measured in a range of human biospecimens, including nasal fluid (N=158), saliva (N=158), exhaled breath condensate (N=40), serum (N=232), and urine (N=429). All samples were analyzed using an HPLC-fluorescence method with high sensitivity and specificity. Due to the right skewed distribution of free MDA and total MDA, we performed natural-log transformation before subsequent statistical analyses. The relationship between the natural log of free and total MDA was evaluated by R of simple linear regression. T test was ...
The journal of spinal cord medicine, Jan 9, 2018
Individuals with chronic spinal cord injury (SCI) have an increased risk of morbidity and mortali... more Individuals with chronic spinal cord injury (SCI) have an increased risk of morbidity and mortality attributable to respiratory diseases. Previous studies in non-SCI populations suggest that vitamin D may be a determinant of respiratory health. Therefore, we sought to assess if lower vitamin D levels were associated with decreased pulmonary function in persons with chronic SCI. Cross-sectional study. Veterans Affairs Medical Center. 312 participants (260 men and 52 women) with chronic SCI recruited from VA Boston and the community participating in an epidemiologic study to assess factors influencing respiratory health. Participants provided a blood sample, completed a respiratory health questionnaire, and underwent spirometry. Linear regression methods were used to assess cross-sectional associations between plasma 25-hydroxyviatmin D and spirometric measures of pulmonary function. Forced expiratory volume in one second (FEV), forced vital capacity (FVC), and FEV/FVC. Adjusted and u...
Archives of physical medicine and rehabilitation, Oct 22, 2016
To identify associations between objective and self-reported measures of physical activity (PA) a... more To identify associations between objective and self-reported measures of physical activity (PA) and relationships with depression and satisfaction with life (SWL) in persons with spinal cord injury (SCI). Retrospective, cross-sectional study of objectively measured wheelchair propulsion (WCP) from 2 studies in which an odometer was attached to participants' wheelchairs to record daily speed and distance. Self-reported data were collected in a separate study examining dyspnea, PA, mood, and SWL. Outpatient clinic in a rehabilitation center. Individuals (N=86) with traumatic SCI who use a manual wheelchair. Not applicable. Objective measures of PA included average daily distance and speed of WCP measured by an odometer. Self-report questionnaires included demographics, the 24-hour recall of transfers, Physical Activity Recall Assessment for People with SCI, the Patient Health Questionnaire-2 (PHQ-2) to document depressive symptoms, and the Satisfaction With Life Scale (SWLS). Both...
Archives of physical medicine and rehabilitation, Oct 4, 2016
Assess relationships between measures of activity with dyspnea and satisfaction with life in chro... more Assess relationships between measures of activity with dyspnea and satisfaction with life in chronic spinal cord injury (SCI) DESIGN: Cross-sectional survey SETTING: Five SCI centers PARTICIPANTS: Between 7/2012-3/2015, 347 subjects with traumatic SCI ≥ 1 year after injury who used a manual wheelchair or walked with or without an assistive device reported hours spent away from home or yard on the previous 3 days, sports participation, and planned exercise. Not applicable MAIN OUTCOME MEASURES: Satisfaction With Life Scale (SWLS). Dyspnea was defined as shortness of breath when hurrying on the level or going up a slight hill, or going slower than people the same age on the level because of breathlessness, or stopping for breath when going at your own pace, or after about 100 yards (or after a few minutes) on the level. Dyspnea prevalence was 30.0%. Adjusting for asthma or COPD, mobility mode, race, and season, there was a significant linear trend between greater SWLS and quartiles of...
American Journal of Physical Medicine & Rehabilitation, May 1, 2007
American Journal of Respiratory and Critical Care Medicine, Apr 1, 2008
Respiratory Medicine, Jul 1, 2012
Journal of Spinal Cord Medicine, Feb 9, 2018
Environmental Health Perspectives, Jul 1, 2006
PLOS ONE
This study investigated the associations between solar and geomagnetic activity and circulating b... more This study investigated the associations between solar and geomagnetic activity and circulating biomarkers of systemic inflammation and endothelial activation in the Normative Aging Study (NAS) cohort. Mixed effects models with moving day averages from day 0 to day 28 were used to study the associations between solar activity (sunspot number (SSN), interplanetary magnetic field (IMF)), geomagnetic activity (planetary K index (Kpindex), and various inflammatory and endothelial markers. Biomarkers included intracellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), C-reactive protein (CRP), and fibrinogen. After adjusting for demographic and meteorological variables, we observed significant positive associations between sICAM-1 and sVCAM-1 concentrations and solar and geomagnetic activity parameters: IMF, SSN, and Kp. Additionally, a negative association was observed between fibrinogen and Kpindex and a positive association was observed for CRP and SSN. T...
Journal of Exposure Science & Environmental Epidemiology, 2022
Environment International, 2020
Environmental Pollution, 2019
Environmental Research, 2019
Environmental Research, 2019
Environment International, 2019
Environmental Research Communications, 2019
Journal of thoracic disease, 2018
Oxidative stress is involved in thoracic diseases and health responses to air pollution. Malondia... more Oxidative stress is involved in thoracic diseases and health responses to air pollution. Malondialdehyde (MDA) is a well-established marker of oxidative stress, but it may be present in unconjugated and conjugated forms. To our knowledge, no studies have conducted a systemic evaluation of both free MDA (unconjugated MDA) and total MDA (the sum of both unconjugated and conjugated MDA) across various types of human biospecimens. Free MDA and total MDA were simultaneously measured in a range of human biospecimens, including nasal fluid (N=158), saliva (N=158), exhaled breath condensate (N=40), serum (N=232), and urine (N=429). All samples were analyzed using an HPLC-fluorescence method with high sensitivity and specificity. Due to the right skewed distribution of free MDA and total MDA, we performed natural-log transformation before subsequent statistical analyses. The relationship between the natural log of free and total MDA was evaluated by R of simple linear regression. T test was ...
The journal of spinal cord medicine, Jan 9, 2018
Individuals with chronic spinal cord injury (SCI) have an increased risk of morbidity and mortali... more Individuals with chronic spinal cord injury (SCI) have an increased risk of morbidity and mortality attributable to respiratory diseases. Previous studies in non-SCI populations suggest that vitamin D may be a determinant of respiratory health. Therefore, we sought to assess if lower vitamin D levels were associated with decreased pulmonary function in persons with chronic SCI. Cross-sectional study. Veterans Affairs Medical Center. 312 participants (260 men and 52 women) with chronic SCI recruited from VA Boston and the community participating in an epidemiologic study to assess factors influencing respiratory health. Participants provided a blood sample, completed a respiratory health questionnaire, and underwent spirometry. Linear regression methods were used to assess cross-sectional associations between plasma 25-hydroxyviatmin D and spirometric measures of pulmonary function. Forced expiratory volume in one second (FEV), forced vital capacity (FVC), and FEV/FVC. Adjusted and u...
Archives of physical medicine and rehabilitation, Oct 22, 2016
To identify associations between objective and self-reported measures of physical activity (PA) a... more To identify associations between objective and self-reported measures of physical activity (PA) and relationships with depression and satisfaction with life (SWL) in persons with spinal cord injury (SCI). Retrospective, cross-sectional study of objectively measured wheelchair propulsion (WCP) from 2 studies in which an odometer was attached to participants' wheelchairs to record daily speed and distance. Self-reported data were collected in a separate study examining dyspnea, PA, mood, and SWL. Outpatient clinic in a rehabilitation center. Individuals (N=86) with traumatic SCI who use a manual wheelchair. Not applicable. Objective measures of PA included average daily distance and speed of WCP measured by an odometer. Self-report questionnaires included demographics, the 24-hour recall of transfers, Physical Activity Recall Assessment for People with SCI, the Patient Health Questionnaire-2 (PHQ-2) to document depressive symptoms, and the Satisfaction With Life Scale (SWLS). Both...
Archives of physical medicine and rehabilitation, Oct 4, 2016
Assess relationships between measures of activity with dyspnea and satisfaction with life in chro... more Assess relationships between measures of activity with dyspnea and satisfaction with life in chronic spinal cord injury (SCI) DESIGN: Cross-sectional survey SETTING: Five SCI centers PARTICIPANTS: Between 7/2012-3/2015, 347 subjects with traumatic SCI ≥ 1 year after injury who used a manual wheelchair or walked with or without an assistive device reported hours spent away from home or yard on the previous 3 days, sports participation, and planned exercise. Not applicable MAIN OUTCOME MEASURES: Satisfaction With Life Scale (SWLS). Dyspnea was defined as shortness of breath when hurrying on the level or going up a slight hill, or going slower than people the same age on the level because of breathlessness, or stopping for breath when going at your own pace, or after about 100 yards (or after a few minutes) on the level. Dyspnea prevalence was 30.0%. Adjusting for asthma or COPD, mobility mode, race, and season, there was a significant linear trend between greater SWLS and quartiles of...