Howard Erickson - Academia.edu (original) (raw)
Papers by Howard Erickson
Kansas State University was one of the most important veterinary colleges to educate African Amer... more Kansas State University was one of the most important veterinary colleges to educate African American veterinarians before Tuskegee Institute (now University) established a veterinary college in 1945. Of the 70 Blacks who received DVM degrees before Tuskegee opened, about a third of them were graduates of Kansas State University. Moreover, unlike Cornell and the University of Pennsylvania, where the majority of the Black students studied during the early decades of the 20 th century, Kansas State's Black veterinary graduates were distributed evenly between 1910 and 1950.
Journal of Veterinary Medicine Series A, 1995
With 1 figure and 3 tables
Equine Veterinary Journal, 1986
parameters in horses exercising after propranolol administration to block P-adrenergic receptors.... more parameters in horses exercising after propranolol administration to block P-adrenergic receptors.. They noted significant Cardiopulmonary responses of four ponies were monitored decreases in performance, heart rate, plasma glucose, free fatty during standard exercise tests (SET), before and after /3acids, glycerol and lactate during exercise. Sweating has also adrenergic receptor blockade with propranolol. The SET been shown to be under 0-adrenergic control (Snow 1977). consisted of four 5 min increments of increasing speed from 1.0 This is the first reported study in which the changes in the to 2.8 m/sec on a treadmill at a 7 ' incline. Data werecollected at haemodynamic and respiratory responses to exercise in the propranolol to ponies at rest had no effect on cardiopulmonary The purpose of this study was to assess the involvement of 0function. During the SET, increases in heart rate, mean pult o exercise in the pony using a standard exercise test (SET). right ventricular dP/dt (an index of myocardial contractility) rest' throughout the SET and recovery' Administration Of equine have been measured following P-adrenergic blockade. monary artery flow velocity (an index of cardiac output) and adrenergic receptors in the normal cardiopulmonary responses were progressively attenuated as running speed increased. Body temperature and mean pulmonary artery and right ventricular Methods pressures were significantly elevated over normal. Propranolol Four ponies 166+.23 kg, were used. The ponies had recently treatment had no effect on the responses of mean arterial completed an intensive eight week programme of endurance pressure, haematocrit, haemoglobin, blood lactate and arterial and interval training. At the end of the training period they were blood gases and pH to the SET. These results suggest that in the subjected to a SET on a treadmill (MLR Designs, Sandusky, pony there is no sympathetic activity to the heart at rest and that Ohio) to evaluate their cardiopulmonary and metabolic fitness. during exercise there is pulmonary vasodilation mediated by PEach pony was subsequently subjected to the same SET after propranolol administration, a normal SET, and then another adrenergic receptors.
Equine Veterinary Journal, 1999
Equine Veterinary Journal, 1998
Blood was taken from 49 Thoroughbred horses before and after racing at the track to determine if ... more Blood was taken from 49 Thoroughbred horses before and after racing at the track to determine if frusemide modified the apparent viscosity of the blood and to determine the effects of changes in shear rate and packed cell volume (PCV), associated with strenuous exercise, on apparent and relative viscosities. Small increases in apparent viscosity of the blood (at a specified PCV and shear rate) occurred in horses given frusemide compared to those receiving no frusemide; however, no differences were seen in relative viscosity. Although 2 groups of horses, those receiving frusemide before racing and those not receiving this drug were studied, the results suggest no influence of frusemide on any red blood cell variable that might modify apparent blood viscosity. Apparent viscosity of the blood was slightly (but significantly) higher after racing than before racing at any given PCV and shear rate, but relative viscosity was lower in the post race than in the prerace blood sample. The most important contributing factor to the increase in apparent viscosity in blood during racing is the increase in PCV, because the blood becomes nearly shear rate independent at shear rates likely to exist in the cardiovascular system during exercise. With an increase in PCV from 40 to 65% at shear rates above 225/s, apparent viscosity approximately doubled. However, this increase alone cannot account for the elevated pulmonary vascular pressure in the running horse, and additional factors, especially those causing the high left atrial pressure, must be considered. The cause of the elevated pressure may be multifactorial in nature.
Journal of Applied Physiology, 1973
... 2/1973. Investigation of the relationship between coronary flow, heart rate, left ventricular... more ... 2/1973. Investigation of the relationship between coronary flow, heart rate, left ventricular function, and myocardial oxygen consumption at increasing levels of carboxyhemoglobin in conscious dogs. The results demonstrate ...
Veterinary heritage : bulletin of the American Veterinary History Society, 2012
The women described in this paper were the early pioneers in veterinary medicine; they studied in... more The women described in this paper were the early pioneers in veterinary medicine; they studied in some of the best veterinary colleges in the world at that time. They paved the way for other women who studied veterinary medicine in later years. According to Drum and Whitely,25 by 1936, there were only 30 female veterinarians in the United States; this was an era when admission to veterinary college for women was nearly impossible. In 1963, there were 277 female veterinarians in the United States, but by 1987 women made up 17% of the veterinary profession. The February 15, 2010 issue of the JAVMA reported that male enrollment in U.S. veterinary colleges decreased from 89% for the 1969-70 school year to 22.4% for 2008-09. During the same period female enrollment increased from 11.0% to 77.6%.
Biomedical sciences instrumentation, 1994
This article discusses exercise-induced pulmonary hemorrhage (EIPH), a pathophysiological syndrom... more This article discusses exercise-induced pulmonary hemorrhage (EIPH), a pathophysiological syndrome which occurs worldwide in the equine athlete. It reviews the history of EIPH, the incidence in performance horses, the etiology, studies performed on the treadmill to determine the mechanisms of EIPH, and the most likely causes of stress failure of the pulmonary capillaries.
Aerospace medicine, 1974
ABSTRACT
Medicine & Science in Sports & Exercise, 1972
Medicine & Science in Sports & Exercise, 1998
Journal of Equine Veterinary Science, 2003
... BOOKMARK ARTICLE. Equine Maximal Oxygen Uptake. Howard Erickson. No abstract is available. To... more ... BOOKMARK ARTICLE. Equine Maximal Oxygen Uptake. Howard Erickson. No abstract is available. To read the body of this article, please view the Full Text online. PII: S0737-0806(03) 01003-7. doi:10.1016/S0737-0806(03)01003-7. View previous. 3 of 16 View next. ...
Equine Veterinary Journal, 2010
Equine Veterinary Journal, 2006
During high intensity exercise, the very high pulmonary artery pressure (Ppa) experienced by Thor... more During high intensity exercise, the very high pulmonary artery pressure (Ppa) experienced by Thoroughbred horses is considered a major factor in the aetiology of exercise-induced pulmonary haemorrhage (EIPH). Recently, endothelin-1 (ET-1), a potent vasoconstrictive hormone, has been found to increase Ppa in horses at rest via binding to its ET-1A receptor subtype. In addition, plasma concentrations of ET-1 are increased in horses during and after high intensity exercise. If ET-1 increases Ppa during exercise in the horse, administration of a specific ET-1A antagonist would decrease Ppa and therefore EIPH. Saline (CON) or an ET-1A receptor antagonist, TBC3214 (3 mg/kg bwt i.v.; ANTAG) was administered to horses 1 h prior to maximal incremental exercise on a high-speed treadmill. Gas exchange measurements were made breath-by-breath and blood samples collected during each 1 min stage to determine blood gases, acid-base status and cardiac output. EIPH was determined via bronchoalveolar lavage (BAL) approximately 30 min after exercise. The time to fatigue, gas exchange and cardiovascular responses were not different between groups (P>0.05). Resting and peak Ppa did not differ significantly between treatments. Most importantly, ANTAG did not decrease EIPH. These results do not support a deterministic role for ET-1 in the increased Ppa and therefore EIPH, during maximal exercise in the equine athlete. Treatment with an ET-1A receptor antagonist does not appear to be a viable therapeutic intervention in the prevention of EIPH.
Equine Veterinary Journal, 2006
Comparative Exercise Physiology, 2008
Abstract—The livestock industry can benefit tremendously from systems that continuously monitor c... more Abstract—The livestock industry can benefit tremendously from systems that continuously monitor cattle state-of-health, allowing the industry to maintain high meat quality, react to the presence of disease, and predict its spread. Requirements for these monitoring systems are similar to requirements that drive human ambulatory monitoring systems based on wearable sensors and wireless data communication. This paper presents early results from an effort to develop a veterinary telemedicine infrastructure based upon wearable monitoring technology originally developed for home health care. The functional layout of the infrastructure is described, and initial hardware and physiological measurements are presented.
The purpose of this investigation was to study the effects of an equine nasal strip (NS), furosem... more The purpose of this investigation was to study the effects of an equine nasal strip (NS), furosemide (Fur), and a combination of both (NS + Fur) on exercise-induced pulmonary hemorrhage (EIPH) at speeds corresponding to near-maximal effort. Five Thoroughbreds (526 +/- 25 kg) were run on a flat treadmill from 7 to 14 m/s in 1 m x s(-1) x min(-)1 increments every 2 wk (treatment order randomized) under control (Con), Fur (1 mg/kg iv 4 h prior), NS, or NS + Fur conditions. During each run, pulmonary arterial (Ppa) and esophageal (Pes) pressures were measured. Severity of EIPH was quantified via bronchoalveolar lavage (BAL) 30 min postrun. Furosemide (Fur and NS + Fur trials) reduced peak Ppa approximately 7 mmHg compared with Con (P < 0.05) whereas NS had no effect (P > 0.05). Maximal Pes swings were not different among groups (P > 0.05). NS significantly diminished EIPH compared with the Con trial [Con, 55.0 +/- 36.2; NS, 30.8 +/- 21.8 x 10(6) red blood cells (RBC)/ml BAL flu...
Kansas State University was one of the most important veterinary colleges to educate African Amer... more Kansas State University was one of the most important veterinary colleges to educate African American veterinarians before Tuskegee Institute (now University) established a veterinary college in 1945. Of the 70 Blacks who received DVM degrees before Tuskegee opened, about a third of them were graduates of Kansas State University. Moreover, unlike Cornell and the University of Pennsylvania, where the majority of the Black students studied during the early decades of the 20 th century, Kansas State's Black veterinary graduates were distributed evenly between 1910 and 1950.
Journal of Veterinary Medicine Series A, 1995
With 1 figure and 3 tables
Equine Veterinary Journal, 1986
parameters in horses exercising after propranolol administration to block P-adrenergic receptors.... more parameters in horses exercising after propranolol administration to block P-adrenergic receptors.. They noted significant Cardiopulmonary responses of four ponies were monitored decreases in performance, heart rate, plasma glucose, free fatty during standard exercise tests (SET), before and after /3acids, glycerol and lactate during exercise. Sweating has also adrenergic receptor blockade with propranolol. The SET been shown to be under 0-adrenergic control (Snow 1977). consisted of four 5 min increments of increasing speed from 1.0 This is the first reported study in which the changes in the to 2.8 m/sec on a treadmill at a 7 ' incline. Data werecollected at haemodynamic and respiratory responses to exercise in the propranolol to ponies at rest had no effect on cardiopulmonary The purpose of this study was to assess the involvement of 0function. During the SET, increases in heart rate, mean pult o exercise in the pony using a standard exercise test (SET). right ventricular dP/dt (an index of myocardial contractility) rest' throughout the SET and recovery' Administration Of equine have been measured following P-adrenergic blockade. monary artery flow velocity (an index of cardiac output) and adrenergic receptors in the normal cardiopulmonary responses were progressively attenuated as running speed increased. Body temperature and mean pulmonary artery and right ventricular Methods pressures were significantly elevated over normal. Propranolol Four ponies 166+.23 kg, were used. The ponies had recently treatment had no effect on the responses of mean arterial completed an intensive eight week programme of endurance pressure, haematocrit, haemoglobin, blood lactate and arterial and interval training. At the end of the training period they were blood gases and pH to the SET. These results suggest that in the subjected to a SET on a treadmill (MLR Designs, Sandusky, pony there is no sympathetic activity to the heart at rest and that Ohio) to evaluate their cardiopulmonary and metabolic fitness. during exercise there is pulmonary vasodilation mediated by PEach pony was subsequently subjected to the same SET after propranolol administration, a normal SET, and then another adrenergic receptors.
Equine Veterinary Journal, 1999
Equine Veterinary Journal, 1998
Blood was taken from 49 Thoroughbred horses before and after racing at the track to determine if ... more Blood was taken from 49 Thoroughbred horses before and after racing at the track to determine if frusemide modified the apparent viscosity of the blood and to determine the effects of changes in shear rate and packed cell volume (PCV), associated with strenuous exercise, on apparent and relative viscosities. Small increases in apparent viscosity of the blood (at a specified PCV and shear rate) occurred in horses given frusemide compared to those receiving no frusemide; however, no differences were seen in relative viscosity. Although 2 groups of horses, those receiving frusemide before racing and those not receiving this drug were studied, the results suggest no influence of frusemide on any red blood cell variable that might modify apparent blood viscosity. Apparent viscosity of the blood was slightly (but significantly) higher after racing than before racing at any given PCV and shear rate, but relative viscosity was lower in the post race than in the prerace blood sample. The most important contributing factor to the increase in apparent viscosity in blood during racing is the increase in PCV, because the blood becomes nearly shear rate independent at shear rates likely to exist in the cardiovascular system during exercise. With an increase in PCV from 40 to 65% at shear rates above 225/s, apparent viscosity approximately doubled. However, this increase alone cannot account for the elevated pulmonary vascular pressure in the running horse, and additional factors, especially those causing the high left atrial pressure, must be considered. The cause of the elevated pressure may be multifactorial in nature.
Journal of Applied Physiology, 1973
... 2/1973. Investigation of the relationship between coronary flow, heart rate, left ventricular... more ... 2/1973. Investigation of the relationship between coronary flow, heart rate, left ventricular function, and myocardial oxygen consumption at increasing levels of carboxyhemoglobin in conscious dogs. The results demonstrate ...
Veterinary heritage : bulletin of the American Veterinary History Society, 2012
The women described in this paper were the early pioneers in veterinary medicine; they studied in... more The women described in this paper were the early pioneers in veterinary medicine; they studied in some of the best veterinary colleges in the world at that time. They paved the way for other women who studied veterinary medicine in later years. According to Drum and Whitely,25 by 1936, there were only 30 female veterinarians in the United States; this was an era when admission to veterinary college for women was nearly impossible. In 1963, there were 277 female veterinarians in the United States, but by 1987 women made up 17% of the veterinary profession. The February 15, 2010 issue of the JAVMA reported that male enrollment in U.S. veterinary colleges decreased from 89% for the 1969-70 school year to 22.4% for 2008-09. During the same period female enrollment increased from 11.0% to 77.6%.
Biomedical sciences instrumentation, 1994
This article discusses exercise-induced pulmonary hemorrhage (EIPH), a pathophysiological syndrom... more This article discusses exercise-induced pulmonary hemorrhage (EIPH), a pathophysiological syndrome which occurs worldwide in the equine athlete. It reviews the history of EIPH, the incidence in performance horses, the etiology, studies performed on the treadmill to determine the mechanisms of EIPH, and the most likely causes of stress failure of the pulmonary capillaries.
Aerospace medicine, 1974
ABSTRACT
Medicine & Science in Sports & Exercise, 1972
Medicine & Science in Sports & Exercise, 1998
Journal of Equine Veterinary Science, 2003
... BOOKMARK ARTICLE. Equine Maximal Oxygen Uptake. Howard Erickson. No abstract is available. To... more ... BOOKMARK ARTICLE. Equine Maximal Oxygen Uptake. Howard Erickson. No abstract is available. To read the body of this article, please view the Full Text online. PII: S0737-0806(03) 01003-7. doi:10.1016/S0737-0806(03)01003-7. View previous. 3 of 16 View next. ...
Equine Veterinary Journal, 2010
Equine Veterinary Journal, 2006
During high intensity exercise, the very high pulmonary artery pressure (Ppa) experienced by Thor... more During high intensity exercise, the very high pulmonary artery pressure (Ppa) experienced by Thoroughbred horses is considered a major factor in the aetiology of exercise-induced pulmonary haemorrhage (EIPH). Recently, endothelin-1 (ET-1), a potent vasoconstrictive hormone, has been found to increase Ppa in horses at rest via binding to its ET-1A receptor subtype. In addition, plasma concentrations of ET-1 are increased in horses during and after high intensity exercise. If ET-1 increases Ppa during exercise in the horse, administration of a specific ET-1A antagonist would decrease Ppa and therefore EIPH. Saline (CON) or an ET-1A receptor antagonist, TBC3214 (3 mg/kg bwt i.v.; ANTAG) was administered to horses 1 h prior to maximal incremental exercise on a high-speed treadmill. Gas exchange measurements were made breath-by-breath and blood samples collected during each 1 min stage to determine blood gases, acid-base status and cardiac output. EIPH was determined via bronchoalveolar lavage (BAL) approximately 30 min after exercise. The time to fatigue, gas exchange and cardiovascular responses were not different between groups (P>0.05). Resting and peak Ppa did not differ significantly between treatments. Most importantly, ANTAG did not decrease EIPH. These results do not support a deterministic role for ET-1 in the increased Ppa and therefore EIPH, during maximal exercise in the equine athlete. Treatment with an ET-1A receptor antagonist does not appear to be a viable therapeutic intervention in the prevention of EIPH.
Equine Veterinary Journal, 2006
Comparative Exercise Physiology, 2008
Abstract—The livestock industry can benefit tremendously from systems that continuously monitor c... more Abstract—The livestock industry can benefit tremendously from systems that continuously monitor cattle state-of-health, allowing the industry to maintain high meat quality, react to the presence of disease, and predict its spread. Requirements for these monitoring systems are similar to requirements that drive human ambulatory monitoring systems based on wearable sensors and wireless data communication. This paper presents early results from an effort to develop a veterinary telemedicine infrastructure based upon wearable monitoring technology originally developed for home health care. The functional layout of the infrastructure is described, and initial hardware and physiological measurements are presented.
The purpose of this investigation was to study the effects of an equine nasal strip (NS), furosem... more The purpose of this investigation was to study the effects of an equine nasal strip (NS), furosemide (Fur), and a combination of both (NS + Fur) on exercise-induced pulmonary hemorrhage (EIPH) at speeds corresponding to near-maximal effort. Five Thoroughbreds (526 +/- 25 kg) were run on a flat treadmill from 7 to 14 m/s in 1 m x s(-1) x min(-)1 increments every 2 wk (treatment order randomized) under control (Con), Fur (1 mg/kg iv 4 h prior), NS, or NS + Fur conditions. During each run, pulmonary arterial (Ppa) and esophageal (Pes) pressures were measured. Severity of EIPH was quantified via bronchoalveolar lavage (BAL) 30 min postrun. Furosemide (Fur and NS + Fur trials) reduced peak Ppa approximately 7 mmHg compared with Con (P < 0.05) whereas NS had no effect (P > 0.05). Maximal Pes swings were not different among groups (P > 0.05). NS significantly diminished EIPH compared with the Con trial [Con, 55.0 +/- 36.2; NS, 30.8 +/- 21.8 x 10(6) red blood cells (RBC)/ml BAL flu...