Esdras Arrieta - Academia.edu (original) (raw)

Papers by Esdras Arrieta

Research paper thumbnail of Efficiency of Coulomb Controlled Iontophoresis for Transcorneal Delivery of Riboflavin: A pilot study

Investigative Ophthalmology & Visual Science, Apr 22, 2011

Research paper thumbnail of Shadowphotogrammetry of IOL Injectors and Clear Cornea Incision Size

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Changes in Primate Crystalline Lens Volume During Simulation of Accommodation in a Lens Stretcher

Investigative Ophthalmology & Visual Science, Apr 22, 2011

Research paper thumbnail of Assessing the Effects of Postmortem Preservation Time on Mouse Lens Properties Using Atomic Force Microscopy and Optical Coherence Tomography

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Age-dependence of mouse lens viscoelasticity

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Primate Lens Capsule and Cortex Elasticity Assessed by Atomic Force Microscopy

Investigative Ophthalmology & Visual Science, Apr 28, 2009

Research paper thumbnail of Age-Related Changes in Lens Power, Thickness and Surface Curvatures with Stretching Force during Simulated Accommodation in Baboons

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Assessing Mouse Lens Elasticity and Viscoelasticity Using Atomic Force Microscopy

Investigative Ophthalmology & Visual Science, Jul 13, 2018

Research paper thumbnail of Ophthalmic Biometry using Calipers: Determination of Measurement Precision

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Age-Dependence of the Power-Load and Diameter-Load Responses of Human and Monkey Lenses During Simulation of Accommodation in a Lens Stretcher

Investigative Ophthalmology & Visual Science, May 10, 2007

Research paper thumbnail of Speed of Ultrasound Gradient Across the Equatorial Profile of the Isolated Human Crystalline Lens

Investigative Ophthalmology & Visual Science, Apr 17, 2010

Research paper thumbnail of Dosimetry for Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT) for treatment of infectious keratitis

Investigative Ophthalmology & Visual Science, 2020

Research paper thumbnail of Compromiso visual por diabetes. Estado actual

Revista Oftalmologica Venezolana, 1999

Research paper thumbnail of Age-dependence of mouse lens viscoelasticity

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Glaucoma Cascade Screening in a High Risk Afro-Caribbean Haitian Population: A Pilot Study

Journal of Glaucoma, 2022

PRCIS Glaucoma cascade screening in first degree relatives of young Haitian glaucoma patients had... more PRCIS Glaucoma cascade screening in first degree relatives of young Haitian glaucoma patients had high yield for diagnosing manifest and suspected glaucoma in 30.8% of those screened despite modest participation. PURPOSE To evaluate the outcomes of glaucoma cascade screening in first-degree relatives (FDRs; parents, siblings and offspring) of Haitian juvenile open angle glaucoma (JOAG) patients. PATIENTS AND METHODS Consecutive index patients (Haitians with JOAG) were identified, and the number/type of FDRs residing in South Florida were recorded. These FDRs were invited for free glaucoma screening, which included a comprehensive ophthalmic exam, gonioscopy, automated visual field testing and optical coherence tomographic analysis of the retinal nerve fiber layers. FDR characteristics and clinical findings from screening are reported. RESULTS A total of 77 FDRs were invited, 26 (33.8%) agreed to undergo screening (18 females, 9 males), which revealed 2 (7.7%) with manifest glaucoma (mean age 77.5▒y; one of whom was previously unaware of his glaucoma diagnosis), 6 (23.1%) with suspected glaucoma (mean age 29.8±18.3▒y), and 18 (69.2%) without manifest or suspected glaucoma (mean age 37.2±21.8▒y). Siblings of index patients were least likely to participate in cascade glaucoma screening when compared to index patients' parents or offspring. FDR eyes with manifest glaucoma had significantly worse best-corrected visual acuities, higher intraocular pressures, thinner central corneal thicknesses, and thinner circumferential papillary retinal nerve fiber layer thicknesses than those without glaucoma. CONCLUSION Glaucoma cascade screening of Haitian JOAG patients' FDRs revealed that 30.8% had suspected or manifest glaucoma. Future efforts centered on provider-initiated recruitment and improving public glaucoma awareness and education may increase screening participation.

Research paper thumbnail of Temperature affects the biomechanical response of in vitro non-human primate lenses during lens stretching

Experimental Eye Research, 2022

To determine the effect of temperature on the accommodative response of non-human primate crystal... more To determine the effect of temperature on the accommodative response of non-human primate crystalline lenses during simulated accommodation. Eight lenses from 7 cynomolgus monkeys (Macaca fascicularis, ages: 4.5-7.3 years; post-mortem time: 17.0 ± 16.4 h) were mounted in a lens stretcher. Stretching experiments were performed on each lens at 24 °C (room temperature), then the tissue was warmed to 35 °C (intraocular temperature) and the stretching experiments were repeated. The lens diameter, thickness, anterior and posterior surface radii of curvature, optical power, and the stretching force (load) were measured at each stretch position and the linear optomechanical relationships were quantified: load-lens diameter, load-thickness, power-load, load-anterior radius, and load-posterior radius. The rate of change for each parameter was quantified by performing a linear regression. The slopes of the linear regressions were compared at the two temperatures using a paired sample t-test. The average changes in the lens with stretching at 24 °C and 35 °C were: 3.07 ± 0.17 and 2.58 ± 0.15 for load-lens diameter (g/mm), -2.38 ± 0.20 and -2.00 ± 0.32 for load-thickness (g/mm), -13.35 ± 1.21 and -13.75 ± 1.26 for power-load (D/g), 0.41 ± 0.10 and 0.34 ± 0.05 for load-anterior radius of curvature (g/mm), and 1.35 ± 0.24 and 1.31 ± 0.35 for load-posterior radius of curvature (g/mm), respectively. The changes in load-diameter and load-thickness with lens stretching were significantly different for the two temperatures. Temperature influences the change in lens shape observed during simulated accommodation in non-human primate lenses. These results suggest that lens stretching experiments and other optomechanical measurement techniques on ex vivo crystalline lenses be conducted at 35 °C and that the temperature of the tissue sample be documented and maintained constant to ensure repeatability.

Research paper thumbnail of Comparison Among New Glaucoma Drainage Device Prototypes: Midi Ray

Investigative Ophthalmology & Visual Science, 2008

Research paper thumbnail of Speed of Ultrasound Gradient Across the Equatorial Profile of the Isolated Human Crystalline Lens

Investigative Ophthalmology & Visual Science, 2010

Research paper thumbnail of A New Corneal Epithelium Dehydration Rate Measurement Technique

Investigative Ophthalmology & Visual Science, 2012

Research paper thumbnail of Clinical Evaluation of Paclitaxel Drug Eluting Implant for the Treatment of Glaucoma in a Rabbit Model

Investigative Ophthalmology & Visual Science, 2010

Research paper thumbnail of Efficiency of Coulomb Controlled Iontophoresis for Transcorneal Delivery of Riboflavin: A pilot study

Investigative Ophthalmology & Visual Science, Apr 22, 2011

Research paper thumbnail of Shadowphotogrammetry of IOL Injectors and Clear Cornea Incision Size

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Changes in Primate Crystalline Lens Volume During Simulation of Accommodation in a Lens Stretcher

Investigative Ophthalmology & Visual Science, Apr 22, 2011

Research paper thumbnail of Assessing the Effects of Postmortem Preservation Time on Mouse Lens Properties Using Atomic Force Microscopy and Optical Coherence Tomography

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Age-dependence of mouse lens viscoelasticity

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Primate Lens Capsule and Cortex Elasticity Assessed by Atomic Force Microscopy

Investigative Ophthalmology & Visual Science, Apr 28, 2009

Research paper thumbnail of Age-Related Changes in Lens Power, Thickness and Surface Curvatures with Stretching Force during Simulated Accommodation in Baboons

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Assessing Mouse Lens Elasticity and Viscoelasticity Using Atomic Force Microscopy

Investigative Ophthalmology & Visual Science, Jul 13, 2018

Research paper thumbnail of Ophthalmic Biometry using Calipers: Determination of Measurement Precision

Investigative Ophthalmology & Visual Science, Mar 26, 2012

Research paper thumbnail of Age-Dependence of the Power-Load and Diameter-Load Responses of Human and Monkey Lenses During Simulation of Accommodation in a Lens Stretcher

Investigative Ophthalmology & Visual Science, May 10, 2007

Research paper thumbnail of Speed of Ultrasound Gradient Across the Equatorial Profile of the Isolated Human Crystalline Lens

Investigative Ophthalmology & Visual Science, Apr 17, 2010

Research paper thumbnail of Dosimetry for Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT) for treatment of infectious keratitis

Investigative Ophthalmology & Visual Science, 2020

Research paper thumbnail of Compromiso visual por diabetes. Estado actual

Revista Oftalmologica Venezolana, 1999

Research paper thumbnail of Age-dependence of mouse lens viscoelasticity

Investigative Ophthalmology & Visual Science, Jul 22, 2019

Research paper thumbnail of Glaucoma Cascade Screening in a High Risk Afro-Caribbean Haitian Population: A Pilot Study

Journal of Glaucoma, 2022

PRCIS Glaucoma cascade screening in first degree relatives of young Haitian glaucoma patients had... more PRCIS Glaucoma cascade screening in first degree relatives of young Haitian glaucoma patients had high yield for diagnosing manifest and suspected glaucoma in 30.8% of those screened despite modest participation. PURPOSE To evaluate the outcomes of glaucoma cascade screening in first-degree relatives (FDRs; parents, siblings and offspring) of Haitian juvenile open angle glaucoma (JOAG) patients. PATIENTS AND METHODS Consecutive index patients (Haitians with JOAG) were identified, and the number/type of FDRs residing in South Florida were recorded. These FDRs were invited for free glaucoma screening, which included a comprehensive ophthalmic exam, gonioscopy, automated visual field testing and optical coherence tomographic analysis of the retinal nerve fiber layers. FDR characteristics and clinical findings from screening are reported. RESULTS A total of 77 FDRs were invited, 26 (33.8%) agreed to undergo screening (18 females, 9 males), which revealed 2 (7.7%) with manifest glaucoma (mean age 77.5▒y; one of whom was previously unaware of his glaucoma diagnosis), 6 (23.1%) with suspected glaucoma (mean age 29.8±18.3▒y), and 18 (69.2%) without manifest or suspected glaucoma (mean age 37.2±21.8▒y). Siblings of index patients were least likely to participate in cascade glaucoma screening when compared to index patients' parents or offspring. FDR eyes with manifest glaucoma had significantly worse best-corrected visual acuities, higher intraocular pressures, thinner central corneal thicknesses, and thinner circumferential papillary retinal nerve fiber layer thicknesses than those without glaucoma. CONCLUSION Glaucoma cascade screening of Haitian JOAG patients' FDRs revealed that 30.8% had suspected or manifest glaucoma. Future efforts centered on provider-initiated recruitment and improving public glaucoma awareness and education may increase screening participation.

Research paper thumbnail of Temperature affects the biomechanical response of in vitro non-human primate lenses during lens stretching

Experimental Eye Research, 2022

To determine the effect of temperature on the accommodative response of non-human primate crystal... more To determine the effect of temperature on the accommodative response of non-human primate crystalline lenses during simulated accommodation. Eight lenses from 7 cynomolgus monkeys (Macaca fascicularis, ages: 4.5-7.3 years; post-mortem time: 17.0 ± 16.4 h) were mounted in a lens stretcher. Stretching experiments were performed on each lens at 24 °C (room temperature), then the tissue was warmed to 35 °C (intraocular temperature) and the stretching experiments were repeated. The lens diameter, thickness, anterior and posterior surface radii of curvature, optical power, and the stretching force (load) were measured at each stretch position and the linear optomechanical relationships were quantified: load-lens diameter, load-thickness, power-load, load-anterior radius, and load-posterior radius. The rate of change for each parameter was quantified by performing a linear regression. The slopes of the linear regressions were compared at the two temperatures using a paired sample t-test. The average changes in the lens with stretching at 24 °C and 35 °C were: 3.07 ± 0.17 and 2.58 ± 0.15 for load-lens diameter (g/mm), -2.38 ± 0.20 and -2.00 ± 0.32 for load-thickness (g/mm), -13.35 ± 1.21 and -13.75 ± 1.26 for power-load (D/g), 0.41 ± 0.10 and 0.34 ± 0.05 for load-anterior radius of curvature (g/mm), and 1.35 ± 0.24 and 1.31 ± 0.35 for load-posterior radius of curvature (g/mm), respectively. The changes in load-diameter and load-thickness with lens stretching were significantly different for the two temperatures. Temperature influences the change in lens shape observed during simulated accommodation in non-human primate lenses. These results suggest that lens stretching experiments and other optomechanical measurement techniques on ex vivo crystalline lenses be conducted at 35 °C and that the temperature of the tissue sample be documented and maintained constant to ensure repeatability.

Research paper thumbnail of Comparison Among New Glaucoma Drainage Device Prototypes: Midi Ray

Investigative Ophthalmology & Visual Science, 2008

Research paper thumbnail of Speed of Ultrasound Gradient Across the Equatorial Profile of the Isolated Human Crystalline Lens

Investigative Ophthalmology & Visual Science, 2010

Research paper thumbnail of A New Corneal Epithelium Dehydration Rate Measurement Technique

Investigative Ophthalmology & Visual Science, 2012

Research paper thumbnail of Clinical Evaluation of Paclitaxel Drug Eluting Implant for the Treatment of Glaucoma in a Rabbit Model

Investigative Ophthalmology & Visual Science, 2010