Eugene Perepeka - Academia.edu (original) (raw)
Uploads
Papers by Eugene Perepeka
Ukrainian Journal of Cardiovascular Surgery
Chronic right ventricular myocardial pacing causes an asynchronous pattern of left ventricular ac... more Chronic right ventricular myocardial pacing causes an asynchronous pattern of left ventricular activation, reduces left ventricular ejection fraction (LVEF), and may be associated with worsening of clinical outcomes in the long term. Although with the emergence of algorithms that minimize ventricular pacing it became possible to reduce the percentage of paced complexes in patients with sinus node dysfunction, permanent ventricular pacing is still inevitable in patients with high-degree atrioventricular (AV) block. The use of permanent conduction system pacing is a promising method for preserving the physiological activation of the ventricular myocardium and preventing the development of heart failure due to ventricular dyssynchrony. The aim. To analyze the immediate and long-term results of the use of conduction system pacing in patients with indications for permanent ventricular pacing. Materials and methods. This study included 18 patients with indications for permanentventricular...
Ukrainian Journal of Cardiovascular Surgery
Right ventricular pacing may impair left ventricular systolic function in patients with reduced l... more Right ventricular pacing may impair left ventricular systolic function in patients with reduced left ventricular ejection fraction (LVEF). The aim. To determine the frequency of pacing-induced cardiomyopathy (PICM) in patients with permanent right ventricular pacing (at least 90%) and preserved LVEF (≥50%). To determine the risk factors for the occurrence of PICM. Materials and methods. The study included 34 patients with indications for permanent ventricular pacing in whom pacemaker was implanted from 2012 to 2022 (mean follow-up period 44.97 ± 28.45 months). PICM was defined as a decrease in LVEF <45% during follow-up regardless of clinical manifestations. Risk factors for PICM were determined through univariate and multivariate regression analysis. Results. The incidence of PICM in this study was 26% during the mean observation period of 44.9 ± 28.4 months. The mean time to the onset of PICM was 29 months in 5 out of 9 patients (55%), the time from implantation to diagnosis of...
Ukrainian Journal of Cardiovascular Surgery, 2022
Background. Implementation of conduction system permanent pacing methods in patients with cardiac... more Background. Implementation of conduction system permanent pacing methods in patients with cardiac bradyarrhythmias allows to maintain the physiological sequence of excitation and contraction of the ventricles and to avoid the development of heart failure due to electrical and mechanical dyssynchrony in patients with high rates of ventricular pacing. Case description. A 61-year-old female patient was examined and treated at the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine from January 25 to January 27, 2022 at the department of surgical treatment of complex cardiac arrhythmias with a diagnosis of proximal complete atrioventricular block. A two-chamber pacemaker (Vitatron Q50A2) with a ventricular lead to stimulate the His bundle region (Medtronic 3830, 69 cm) was implanted to the patient with a special delivery system (C315HIS). At an X-ray operating room, 12 ECG leads from the electrophysiological station LabSystem Pro (B...
Ukrainian Journal of Cardiovascular Surgery
Chronic right ventricular myocardial pacing causes an asynchronous pattern of left ventricular ac... more Chronic right ventricular myocardial pacing causes an asynchronous pattern of left ventricular activation, reduces left ventricular ejection fraction (LVEF), and may be associated with worsening of clinical outcomes in the long term. Although with the emergence of algorithms that minimize ventricular pacing it became possible to reduce the percentage of paced complexes in patients with sinus node dysfunction, permanent ventricular pacing is still inevitable in patients with high-degree atrioventricular (AV) block. The use of permanent conduction system pacing is a promising method for preserving the physiological activation of the ventricular myocardium and preventing the development of heart failure due to ventricular dyssynchrony. The aim. To analyze the immediate and long-term results of the use of conduction system pacing in patients with indications for permanent ventricular pacing. Materials and methods. This study included 18 patients with indications for permanentventricular...
Ukrainian Journal of Cardiovascular Surgery
Right ventricular pacing may impair left ventricular systolic function in patients with reduced l... more Right ventricular pacing may impair left ventricular systolic function in patients with reduced left ventricular ejection fraction (LVEF). The aim. To determine the frequency of pacing-induced cardiomyopathy (PICM) in patients with permanent right ventricular pacing (at least 90%) and preserved LVEF (≥50%). To determine the risk factors for the occurrence of PICM. Materials and methods. The study included 34 patients with indications for permanent ventricular pacing in whom pacemaker was implanted from 2012 to 2022 (mean follow-up period 44.97 ± 28.45 months). PICM was defined as a decrease in LVEF <45% during follow-up regardless of clinical manifestations. Risk factors for PICM were determined through univariate and multivariate regression analysis. Results. The incidence of PICM in this study was 26% during the mean observation period of 44.9 ± 28.4 months. The mean time to the onset of PICM was 29 months in 5 out of 9 patients (55%), the time from implantation to diagnosis of...
Ukrainian Journal of Cardiovascular Surgery, 2022
Background. Implementation of conduction system permanent pacing methods in patients with cardiac... more Background. Implementation of conduction system permanent pacing methods in patients with cardiac bradyarrhythmias allows to maintain the physiological sequence of excitation and contraction of the ventricles and to avoid the development of heart failure due to electrical and mechanical dyssynchrony in patients with high rates of ventricular pacing. Case description. A 61-year-old female patient was examined and treated at the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine from January 25 to January 27, 2022 at the department of surgical treatment of complex cardiac arrhythmias with a diagnosis of proximal complete atrioventricular block. A two-chamber pacemaker (Vitatron Q50A2) with a ventricular lead to stimulate the His bundle region (Medtronic 3830, 69 cm) was implanted to the patient with a special delivery system (C315HIS). At an X-ray operating room, 12 ECG leads from the electrophysiological station LabSystem Pro (B...