FIRAT SAYDAM - Academia.edu (original) (raw)

Papers by FIRAT SAYDAM

Research paper thumbnail of When to add supplemental rectal paracetamol for postoperative analgesia with caudal bupivacaine in children? A prospective, double-blind, randomized study

Pediatric Anesthesia, 2007

Background: The aim of this study was to investigate whether a supplemental dose of rectal parac... more Background: The aim of this study was to investigate whether a supplemental dose of rectal paracetamol at the third or fourth hour would enhance the quality of analgesia provided by caudal epidural blockade in children.Methods: Two hundred and two ASA I patients aged 1–12 years undergoing inguinal surgery were randomized into three groups in the postanesthesia care unit by drawing lots. Patients in the control group did not receive any analgesic until they had a pain score of 5 or higher, patients in the group P3 received rectal paracetamol (20–25 mg·kg−1) at the third hour, and patients in the group P4 received the same dose of rectal paracetamol at the fourth hour after caudal epidural injection. Pain was assessed by VAS (Visual Analog Scale) and supplementary rescue analgesic need was recorded.Results: There was no difference between the demographic data or the duration and variety of surgery among the groups. A significantly lower number of patients required rescue analgesia at the sixth postoperative hour in group P3 and also lower pain scores were again obtained in group P3 at the sixth and eighth postoperative hours.Conclusions: Supplemental rectal paracetamol at the third hour of caudal blockade enhances the quality of postoperative analgesia better than its addition at the fourth hour in children undergoing inguinal surgery.

Research paper thumbnail of Synthesis, Characterization, Electrochemical, and Optic Limiting Properties of Novel CoII, CuII, and Double-Decker LuIII Phthalocyanines

European Journal of Inorganic Chemistry, 2009

The synthesis, spectroscopic, electrochemical, and optical properties of tetrasubstituted CoII, C... more The synthesis, spectroscopic, electrochemical, and optical properties of tetrasubstituted CoII, CuII, and double-decker LuIII phthalocyanines are reported. The new compounds were characterized by elemental analysis, IR and UV/Vis spectroscopy, and MALDI TOF mass spectrometry. Their electrochemistry was studied by cyclic voltammetry and Osteryoung square-wave voltammetry in nonaqueous medium. Nonlinear absorption and optical limiting performance of peripheral-substituted (C30H28N30)4Co (5), (C30H28N30)4Cu (6), and [(C30H28N30)4]2Lu (7) were investigated by the Z-scan technique. Whereas 6 and 7 showed good nonlinear absorption, 5 did not. Optical limiting parameters of the ratio of the excited state to the ground state absorption cross sections κ, the effective nonlinear absorption coefficient βeff, the linear absorption coefficient α0, limiting threshold Fth, and the saturation density or energy density Fsat values were determined for 6 and 7. The results indicated that both compounds exhibited good optical limiting performances. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

Research paper thumbnail of Synthesis, characterization and thermal behavior of 4-chloromethyl-2-(2-hydroxybenzilidenehydrazino) thiazole and its complexes with Cr(III), Co(II), Ni(II) and Cu(II

Spectrochimica Acta Part A-molecular and Biomolecular Spectroscopy, 2006

Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyr... more Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermogravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder diffractometry, infrared spectroscopy, elemental analysis, and complexometry were used to characterize and to study the thermal behaviour of these compounds. The results led to information about the composition, dehydration, ligand denticity, thermal behaviour and thermal decomposition of the isolated compounds.

Research paper thumbnail of Synthesis, characterization and investigation of electrical and electrochemical properties of imidazole substituted phthalocyanines

Inorganica Chimica Acta, 2011

ABSTRACT Compound 1 has been synthesized by the reaction of 4-nitrophthalonitrile and 4,5-dipheny... more ABSTRACT Compound 1 has been synthesized by the reaction of 4-nitrophthalonitrile and 4,5-diphenyl-1H-imidazolethiole in DMSO in the presence of K2CO3. Compound 2 has been synthesized by heating compound 1 with metallic lithium in pentanol and hydrolyzed with hydrochloric acid (10%) and then neutralized with ammonia solution. Compound 3 and 4 have been synthesized by heating 1 with ZnCl2 or CoCl2 in DMF in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), respectively. The new compounds were obtained in sufficient purity after successive washing with different solvents and were characterized by elemental analysis, 1H NMR, 13C NMR, UV–vis, IR and mass spectra. We also studied aggregation behavior, electrochemical and electrical properties of these phthalocyanines. Direct current (dc) and alternating current (ac) conductivity (40–100 kHz) measurements of films of 2, 3 and 4 were performed in the temperature range of 295–523 K. Impedance spectra (IS) of the 2, 3 and 4 were also studied. The conduction processes were discussed. Temperature dependence of dc conductivity of the films revealed that 2, 3 and 4 show a semiconductor behavior. Results of ac measurements showed that, conduction processes of the films of the complex consisted of different mechanisms depending on temperature and frequency.

Research paper thumbnail of The Kinetics and Mechanism of the Pyrolysis of Manganese and Manganese Silicide CVD Precursors

Chemical Vapor Deposition, 1998

Abstract The gas-phase pyrolysis of methyl pentacarbonyl manganese and acetyl pentacarbonyl manga... more Abstract The gas-phase pyrolysis of methyl pentacarbonyl manganese and acetyl pentacarbonyl manganese, both alone and in the presence of trimethyl silane, has been investigated using stirred flow reactor kinetic measurements and IR laser powered ...

Research paper thumbnail of Metal complexes of (LH 2) ligand: 8,9-bis(hydroxyimino)-4,7,10,13-tetraaza-1,2,15,16-O-dicyclopentylidenehexadecane

Lancet, 2001

ABSTRACT Molecular semiconducting complexes constitute one of the most fascinating, recent resear... more ABSTRACT Molecular semiconducting complexes constitute one of the most fascinating, recent research topics, deeply involving both chemists and solid states physicists. Considerable interest has been shown in the synthesis and study of molecular complexes which may behave like semiconducting materials or at least show high conductivities. In this study, structural, electrical and thermal conductivity and optical properties of some inorganic complexes were investigated. From the XRD data, the unit cells of the samples were found as L–Cu is amorphous and L–Ni, L–Co are orthorhombic. L–Cu, L–Ni and L–Co have n-type of electrical conductivity. Electrical and optical band gaps of the complexes were found to be 1.46–1.36, 2.68–2.71 and 1.40–1.32 eV, respectively.

Research paper thumbnail of Hydrogen bonding in meso -4,5-diphenyl-3,6-diazaoctane-1,8-diol: the formation of one-dimensional linear chains of edge-fused rings

Acta Crystallographica Section C-crystal Structure Communications, 2006

Research paper thumbnail of Experimental and Ab Initio Computational Studies on 4-(Benzhydryloxy)phthalonitrile

Molecular Crystals and Liquid Crystals, 2011

Molecular structure, atomic charges, dipole moments, total energies, and vibrational frequencies ... more Molecular structure, atomic charges, dipole moments, total energies, and vibrational frequencies of 4-(benzhydryloxy)phthalonitrile in the ground state have been calculated using density functional theory (DFT) calculations and compared with the experimental data. Calculated frequencies are in good agreement with the corresponding experimental data. To determine conformational flexibility, the molecular energy profile of the title compound was obtained by semi-empirical (RAM1) calculations with respect to the selected torsion angle, which was varied from −180° to +180° in steps of 10°. In addition, frontier molecular orbitals (FMOs) analysis and thermodynamic properties of the title compound were investigated using theoretical calculations.

Research paper thumbnail of SYNTHESIS AND CHARACTERISATION OF THE NEW THIAZOLE SCHIFF BASE 2-(2HYDROXY)NAPHTHYLIDENEAMINO-BENZOTHIAZOLE AND ITS COMPLEXES WITH Co(II), Cu(II), AND Ni(II) IONS

Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 2002

Research paper thumbnail of Mechanisms of pyrolysis of organometallic deposition precursors

Journal of Materials Chemistry, 1994

... lain MT Davidson, Andrew M. Ellis, Graham P. Mills, Mark Pennington, Ian M. Povey, J. Barrie ... more ... lain MT Davidson, Andrew M. Ellis, Graham P. Mills, Mark Pennington, Ian M. Povey, J. Barrie Raynor, Douglas K. Russell,*t Sinan Saydam ... AJ Pearson, in Comprehensive Organometallic Chemistry, ed. G. Wilkinson, FGA Stone and EW Abel, Pergamon Press, Oxford, 1982, vol. ...

Research paper thumbnail of Synthesis, Characterization, and Thermal Behavior of 4-Chloromethyl-2-(2-Hydroxynaphthylidenehydrazino) Thiazole and its Complexes with Cr(III), Co(II), Ni(II), and Cu(II

Synthesis and Reactivity in Inorganic Metal-organic and Nano-metal Chemistry, 2005

Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyr... more Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermogravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder diffractometry, infrared spectroscopy, elemental analysis, and complexometry were used to characterize and to study the thermal behaviour of these compounds. The results led to information about the composition, dehydration, ligand denticity, thermal behaviour and thermal decomposition of the isolated compounds.

Research paper thumbnail of Thoracic epidural anaesthesia and analgesia with bupivacaine for transsternal thymectomy for myasthenia gravis

European Journal of Anaesthesiology, 1997

intra-operative relaxation followed by an uneventful recovery and eliminated the need for other p... more intra-operative relaxation followed by an uneventful recovery and eliminated the need for other post-op-The present study describes the management of a erative analgesics. myasthenic patient undergoing transsternal thymectomy for whom thoracic epidural anaesthesia using Keywords: anaesthetic technique, thoracic epidural, general; autoimmune disease, myasthenia gravis; sur-15 mL of bupivacaine 0.5% combined with isoflurane 0.4% and nitrous oxide in oxygen 50% provided good gery, transsternal thymectomy.

Research paper thumbnail of Investigation of Oxidative Status of the 2Furan2-yl-1 H Benzimidazole in Rats

Biological Trace Element Research, 2008

We investigated the influence of 2-furan-2-yl-1H-benzimidazole regarding vitamins A, E, C, seleni... more We investigated the influence of 2-furan-2-yl-1H-benzimidazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA), and glutathione peroxidase (GSH-Px) levels on rats. 2-Furan-2-yl-1H-benzimidazole was given to rats by subcutaneous injection every other day for a total of 22 injections. At the end of the experiment, Se levels were determined by using a fluorimetric method. Serum levels of vitamins A, E, C, and malondialdehyde (MDA) were determined by high-performance liquid chromatography. Glutathione peroxidase (GSH-Px) levels of erythrocytes were spectrophotometrically determined. Our experimental results showed that vitamins A, E, C, and Se levels were found generally lower than the control groups, while serum MDA level and GSH-Px activity flexibly increased, which is dependent on injection days. The observed decreases in vitamins A, E, C, and Se levels in the blood might be causally related to the increased amount of free radicals that are generated with 2-furan-2-yl-1H-benzimidazole injection. However, further investigations are needed to clarify the significance of this observation in respect with the 2-furan-2-yl-1H-benzimidazole injection.

Research paper thumbnail of Mechanisms of Pyrolysis of Tricarbonylcyclopentadienylmanganese and Tricarbonyl(methylcyclopentadienyl)manganese

Organometallics, 1995

Grup ġirketler, Özel sektör, Özel yetkili servisler, Resmi kurumlar, Transit Ticaret, Tüketici, A... more Grup ġirketler, Özel sektör, Özel yetkili servisler, Resmi kurumlar, Transit Ticaret, Tüketici, Alternatif sevk adresleri, Bayiler gibi sistemde tanımlanan MüĢteri Gruplarıdır.

Research paper thumbnail of When to add supplemental rectal paracetamol for postoperative analgesia with caudal bupivacaine in children? A prospective, double-blind, randomized study

Pediatric Anesthesia, 2007

Background: The aim of this study was to investigate whether a supplemental dose of rectal parac... more Background: The aim of this study was to investigate whether a supplemental dose of rectal paracetamol at the third or fourth hour would enhance the quality of analgesia provided by caudal epidural blockade in children.Methods: Two hundred and two ASA I patients aged 1–12 years undergoing inguinal surgery were randomized into three groups in the postanesthesia care unit by drawing lots. Patients in the control group did not receive any analgesic until they had a pain score of 5 or higher, patients in the group P3 received rectal paracetamol (20–25 mg·kg−1) at the third hour, and patients in the group P4 received the same dose of rectal paracetamol at the fourth hour after caudal epidural injection. Pain was assessed by VAS (Visual Analog Scale) and supplementary rescue analgesic need was recorded.Results: There was no difference between the demographic data or the duration and variety of surgery among the groups. A significantly lower number of patients required rescue analgesia at the sixth postoperative hour in group P3 and also lower pain scores were again obtained in group P3 at the sixth and eighth postoperative hours.Conclusions: Supplemental rectal paracetamol at the third hour of caudal blockade enhances the quality of postoperative analgesia better than its addition at the fourth hour in children undergoing inguinal surgery.

Research paper thumbnail of Synthesis, Characterization, Electrochemical, and Optic Limiting Properties of Novel CoII, CuII, and Double-Decker LuIII Phthalocyanines

European Journal of Inorganic Chemistry, 2009

The synthesis, spectroscopic, electrochemical, and optical properties of tetrasubstituted CoII, C... more The synthesis, spectroscopic, electrochemical, and optical properties of tetrasubstituted CoII, CuII, and double-decker LuIII phthalocyanines are reported. The new compounds were characterized by elemental analysis, IR and UV/Vis spectroscopy, and MALDI TOF mass spectrometry. Their electrochemistry was studied by cyclic voltammetry and Osteryoung square-wave voltammetry in nonaqueous medium. Nonlinear absorption and optical limiting performance of peripheral-substituted (C30H28N30)4Co (5), (C30H28N30)4Cu (6), and [(C30H28N30)4]2Lu (7) were investigated by the Z-scan technique. Whereas 6 and 7 showed good nonlinear absorption, 5 did not. Optical limiting parameters of the ratio of the excited state to the ground state absorption cross sections κ, the effective nonlinear absorption coefficient βeff, the linear absorption coefficient α0, limiting threshold Fth, and the saturation density or energy density Fsat values were determined for 6 and 7. The results indicated that both compounds exhibited good optical limiting performances. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

Research paper thumbnail of Synthesis, characterization and thermal behavior of 4-chloromethyl-2-(2-hydroxybenzilidenehydrazino) thiazole and its complexes with Cr(III), Co(II), Ni(II) and Cu(II

Spectrochimica Acta Part A-molecular and Biomolecular Spectroscopy, 2006

Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyr... more Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermogravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder diffractometry, infrared spectroscopy, elemental analysis, and complexometry were used to characterize and to study the thermal behaviour of these compounds. The results led to information about the composition, dehydration, ligand denticity, thermal behaviour and thermal decomposition of the isolated compounds.

Research paper thumbnail of Synthesis, characterization and investigation of electrical and electrochemical properties of imidazole substituted phthalocyanines

Inorganica Chimica Acta, 2011

ABSTRACT Compound 1 has been synthesized by the reaction of 4-nitrophthalonitrile and 4,5-dipheny... more ABSTRACT Compound 1 has been synthesized by the reaction of 4-nitrophthalonitrile and 4,5-diphenyl-1H-imidazolethiole in DMSO in the presence of K2CO3. Compound 2 has been synthesized by heating compound 1 with metallic lithium in pentanol and hydrolyzed with hydrochloric acid (10%) and then neutralized with ammonia solution. Compound 3 and 4 have been synthesized by heating 1 with ZnCl2 or CoCl2 in DMF in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), respectively. The new compounds were obtained in sufficient purity after successive washing with different solvents and were characterized by elemental analysis, 1H NMR, 13C NMR, UV–vis, IR and mass spectra. We also studied aggregation behavior, electrochemical and electrical properties of these phthalocyanines. Direct current (dc) and alternating current (ac) conductivity (40–100 kHz) measurements of films of 2, 3 and 4 were performed in the temperature range of 295–523 K. Impedance spectra (IS) of the 2, 3 and 4 were also studied. The conduction processes were discussed. Temperature dependence of dc conductivity of the films revealed that 2, 3 and 4 show a semiconductor behavior. Results of ac measurements showed that, conduction processes of the films of the complex consisted of different mechanisms depending on temperature and frequency.

Research paper thumbnail of The Kinetics and Mechanism of the Pyrolysis of Manganese and Manganese Silicide CVD Precursors

Chemical Vapor Deposition, 1998

Abstract The gas-phase pyrolysis of methyl pentacarbonyl manganese and acetyl pentacarbonyl manga... more Abstract The gas-phase pyrolysis of methyl pentacarbonyl manganese and acetyl pentacarbonyl manganese, both alone and in the presence of trimethyl silane, has been investigated using stirred flow reactor kinetic measurements and IR laser powered ...

Research paper thumbnail of Metal complexes of (LH 2) ligand: 8,9-bis(hydroxyimino)-4,7,10,13-tetraaza-1,2,15,16-O-dicyclopentylidenehexadecane

Lancet, 2001

ABSTRACT Molecular semiconducting complexes constitute one of the most fascinating, recent resear... more ABSTRACT Molecular semiconducting complexes constitute one of the most fascinating, recent research topics, deeply involving both chemists and solid states physicists. Considerable interest has been shown in the synthesis and study of molecular complexes which may behave like semiconducting materials or at least show high conductivities. In this study, structural, electrical and thermal conductivity and optical properties of some inorganic complexes were investigated. From the XRD data, the unit cells of the samples were found as L–Cu is amorphous and L–Ni, L–Co are orthorhombic. L–Cu, L–Ni and L–Co have n-type of electrical conductivity. Electrical and optical band gaps of the complexes were found to be 1.46–1.36, 2.68–2.71 and 1.40–1.32 eV, respectively.

Research paper thumbnail of Hydrogen bonding in meso -4,5-diphenyl-3,6-diazaoctane-1,8-diol: the formation of one-dimensional linear chains of edge-fused rings

Acta Crystallographica Section C-crystal Structure Communications, 2006

Research paper thumbnail of Experimental and Ab Initio Computational Studies on 4-(Benzhydryloxy)phthalonitrile

Molecular Crystals and Liquid Crystals, 2011

Molecular structure, atomic charges, dipole moments, total energies, and vibrational frequencies ... more Molecular structure, atomic charges, dipole moments, total energies, and vibrational frequencies of 4-(benzhydryloxy)phthalonitrile in the ground state have been calculated using density functional theory (DFT) calculations and compared with the experimental data. Calculated frequencies are in good agreement with the corresponding experimental data. To determine conformational flexibility, the molecular energy profile of the title compound was obtained by semi-empirical (RAM1) calculations with respect to the selected torsion angle, which was varied from −180° to +180° in steps of 10°. In addition, frontier molecular orbitals (FMOs) analysis and thermodynamic properties of the title compound were investigated using theoretical calculations.

Research paper thumbnail of SYNTHESIS AND CHARACTERISATION OF THE NEW THIAZOLE SCHIFF BASE 2-(2HYDROXY)NAPHTHYLIDENEAMINO-BENZOTHIAZOLE AND ITS COMPLEXES WITH Co(II), Cu(II), AND Ni(II) IONS

Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 2002

Research paper thumbnail of Mechanisms of pyrolysis of organometallic deposition precursors

Journal of Materials Chemistry, 1994

... lain MT Davidson, Andrew M. Ellis, Graham P. Mills, Mark Pennington, Ian M. Povey, J. Barrie ... more ... lain MT Davidson, Andrew M. Ellis, Graham P. Mills, Mark Pennington, Ian M. Povey, J. Barrie Raynor, Douglas K. Russell,*t Sinan Saydam ... AJ Pearson, in Comprehensive Organometallic Chemistry, ed. G. Wilkinson, FGA Stone and EW Abel, Pergamon Press, Oxford, 1982, vol. ...

Research paper thumbnail of Synthesis, Characterization, and Thermal Behavior of 4-Chloromethyl-2-(2-Hydroxynaphthylidenehydrazino) Thiazole and its Complexes with Cr(III), Co(II), Ni(II), and Cu(II

Synthesis and Reactivity in Inorganic Metal-organic and Nano-metal Chemistry, 2005

Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyr... more Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La -Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermogravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder diffractometry, infrared spectroscopy, elemental analysis, and complexometry were used to characterize and to study the thermal behaviour of these compounds. The results led to information about the composition, dehydration, ligand denticity, thermal behaviour and thermal decomposition of the isolated compounds.

Research paper thumbnail of Thoracic epidural anaesthesia and analgesia with bupivacaine for transsternal thymectomy for myasthenia gravis

European Journal of Anaesthesiology, 1997

intra-operative relaxation followed by an uneventful recovery and eliminated the need for other p... more intra-operative relaxation followed by an uneventful recovery and eliminated the need for other post-op-The present study describes the management of a erative analgesics. myasthenic patient undergoing transsternal thymectomy for whom thoracic epidural anaesthesia using Keywords: anaesthetic technique, thoracic epidural, general; autoimmune disease, myasthenia gravis; sur-15 mL of bupivacaine 0.5% combined with isoflurane 0.4% and nitrous oxide in oxygen 50% provided good gery, transsternal thymectomy.

Research paper thumbnail of Investigation of Oxidative Status of the 2Furan2-yl-1 H Benzimidazole in Rats

Biological Trace Element Research, 2008

We investigated the influence of 2-furan-2-yl-1H-benzimidazole regarding vitamins A, E, C, seleni... more We investigated the influence of 2-furan-2-yl-1H-benzimidazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA), and glutathione peroxidase (GSH-Px) levels on rats. 2-Furan-2-yl-1H-benzimidazole was given to rats by subcutaneous injection every other day for a total of 22 injections. At the end of the experiment, Se levels were determined by using a fluorimetric method. Serum levels of vitamins A, E, C, and malondialdehyde (MDA) were determined by high-performance liquid chromatography. Glutathione peroxidase (GSH-Px) levels of erythrocytes were spectrophotometrically determined. Our experimental results showed that vitamins A, E, C, and Se levels were found generally lower than the control groups, while serum MDA level and GSH-Px activity flexibly increased, which is dependent on injection days. The observed decreases in vitamins A, E, C, and Se levels in the blood might be causally related to the increased amount of free radicals that are generated with 2-furan-2-yl-1H-benzimidazole injection. However, further investigations are needed to clarify the significance of this observation in respect with the 2-furan-2-yl-1H-benzimidazole injection.

Research paper thumbnail of Mechanisms of Pyrolysis of Tricarbonylcyclopentadienylmanganese and Tricarbonyl(methylcyclopentadienyl)manganese

Organometallics, 1995

Grup ġirketler, Özel sektör, Özel yetkili servisler, Resmi kurumlar, Transit Ticaret, Tüketici, A... more Grup ġirketler, Özel sektör, Özel yetkili servisler, Resmi kurumlar, Transit Ticaret, Tüketici, Alternatif sevk adresleri, Bayiler gibi sistemde tanımlanan MüĢteri Gruplarıdır.