Faiyaz Ahmed - Academia.edu (original) (raw)

Papers by Faiyaz Ahmed

Academic Journals, Feb 28, 2010

Current Research in Nutrition and Food Science Journal, 2021

Acrylamide is a water-soluble compound that forms during the high-temperature cooking of starchy ... more Acrylamide is a water-soluble compound that forms during the high-temperature cooking of starchy foods and has carcinogenic, neurotoxic, and genotoxic properties. Also, short-term exposure to acrylamide has been shown to cause significant hepatic injury in laboratory animals, along with disruption of antioxidant defense mechanisms due to excessive ROS production. Therefore, dietary antioxidants are believed to be useful in combating the negative effects of acrylamide. Corchorus olitoris L., also known as molokhia in Arabic, is a leafy vegetable which is shown to possess potent antioxidant and organoprotective properties. In this study, rats were administered with an aqueous extract of molokhia leaves to see if it could protect them against acrylamide-induced hepatic damage. Hepatic injury markers included serum total protein, total bilirubin, ALT, AST, and ALP, while oxidative stress markers included MDA, GSH, CAT, and SOD after dosing with three levels of extract (100, 250, and 500...

Egyptian Journal of Agricultural Sciences, 2009

This study aimed to investigate the chemical constituents of the perennial Senniella spongiosa st... more This study aimed to investigate the chemical constituents of the perennial Senniella spongiosa stems and leaves under influences of Alexandria-Mersa Mattruh road environmental conditions at 30 km from Alexandria during summer and winter seasons of 2006-2007. Phytochemical screening of the stems and leaves of S. spongiosa revealed some differences in the chemical constituents. Chlorophyll a, b and total carotenoids were high during winter in the leaves compared with the stems in the summer. The moisture content reached its maximum value during winter for plant stems and its minimum value during summer for plant leaves, while the organic matter reached its maximum value during summer for plant stems, and its minimum value during winter for plant leaves. In addition, the total ash content reached its maximum value during summer for plant leaves and its minimum value during winter for plant stems. The percentages of crude fibres and total nitrogen reached their maximum values in winter, for plant leaves and stems. Also, the percentages of total carbohydrates reached their maximum value for plant leaves in winter and minimum value during summer for plant stems. On the other hand, the percentages of total phenolics, alkaloids, tannins and flavonoids reached their maximum values during the summer season for plant leaves and stems, and the lowest values were detected during winter for plant leaves and stems. The phenolic compounds were most abundant in summer. Meanwhile the percentage of total oxalates reached its maximum value during winter season for plant leaves and stems. Moreover, the stems and leaves possessed higher contents of Fe and Zn during the summer season. Proline was accumulated in plant stems and leaves in winter season. while, high glycine betaine and choline hydrochloride contents were found in plant leaves during summer. From these data, it is suggested that under stress S. spongiosa plants tended to accumulate secondary metabolic products, which may be a part of a suite of adaptation to unfavourable conditions.

Citrus medica Linn. (Rutaceae) known as Gajanimbe is used as a folk medicine in the treatment of ... more Citrus medica Linn. (Rutaceae) known as Gajanimbe is used as a folk medicine in the treatment of gastric ulcers. Present study was undertaken to study the effect of aqueous extract of the fruits against water immersion restraint stress-induced ulcers in rats. The extract was subjected to phytochemical screening and found to contain carbohydrates, proteins, amino acids and flavonoids. The rats were pretreated with the extract (250 mg kg-1 p.o.) and the antiulcer effect was compared with that of omeprazole (10 mg kg-1 p.o.). The extract pretreatment showed a significant reduction in ulcer formation and gastric lesions. Histopathological sections showed significant decrease in neutrophil infiltration in gastric mucosal tissues, mucosal ulceration, inflammatory mucosal changes and submucosal edema with regenerated epithelial cells compared to untreated and omeprazole-treated rats. The results emphasize that, the fruits of C. medica possesses significant antiulcer activity against stress-induced ulcers in rats and the antiulcer activity could be due to the presence of flavonoids as these compounds have well documented antiulcer activity.

Antioxidant activity of aq. ext. (DAAE) and methanol ext. (DAME) of Dioscorea alata tuber were ev... more Antioxidant activity of aq. ext. (DAAE) and methanol ext. (DAME) of Dioscorea alata tuber were evaluated using DPPH radical scavenging and reducing power assay. DAME contained significantly higher (p â‰¤ 0.05) phenolics compared to DAAE and showed significantly higher (p â‰¤ 0.05) radical scavenging activity (84%) than DAAE (12.6%). The radical scavenging activity of DAME was comparable with that of BHT (85%) at 100 I¼g/mL concn. DAME also showed higher reducing power than DAAE. A significant (p â‰¤ 0.01) correlation was obsd. between the phenolic content and the radical scavenging activity of the exts. indicating the contribution of phenolic compds. for the obsd. antioxidant effect. [on SciFinder(R)]

Geological Society of America Abstracts with Programs, 2021

$Research paper thumbnail of Redistribution of nutritionally important starch fractions beneficial to diabetic population by using oats as a functional ingredient in a wheat-based food product – Jereesh$

Journal of Food Bioactives, 2021

Oats being important sources of β-glucan were incorporated at 10, 20 and 30% level in a wheat-bas... more Oats being important sources of β-glucan were incorporated at 10, 20 and 30% level in a wheat-based traditional Arabian breakfast cereal called Jereesh and evaluated for sensory acceptability. Sensory analysis reflected that the products with 10 and 20% oats incorporation were acceptable in terms of color, appearance, taste, aroma, mouthfeel, after taste and overall quality as indicated by the sensory scores which revealed no substantial differences between control jereesh (CJ) and oats incorporated jereesh (OJ). However, jereesh with 30% oats incorporation was very sticky (viscous) and scored low in sensory evaluation. Thus, nutritionally important starch fractions were measured in jereesh with 20% oats incorporation using a controlled in vitro multi-enzymatic method. Results indicated that, addition of oats at 20% level resulted in a substantial decrease (p<0.05) in total starch (TS), rapidly available glucose (RAG), and resistant starch content (RS), as well as a significant i...

Pharmacognosy Magazine, 2021

Background: Corchorus olitorius L., commonly known as molokhia in Arabic, is a leafy vegetable co... more Background: Corchorus olitorius L., commonly known as molokhia in Arabic, is a leafy vegetable containing large amounts of mucilaginous polysaccharides and reported to exhibit antidiabetic diabetic activity in experimental diabetes. Although antidiabetic effect of molokhia is attributed to the presence of phenolic and non-phenolic compounds, the precise mechanism of action is not explored. Materials and Methods: The present study investigated the ability of molokhia leaves powder (MLP) to modulate starch digestion and glucose diffusion in vitro. Results: MLP at 2% and 4% levels bound significantly higher amount of glucose than wheat bran (2%) and also reduced diffusion of glucose through dialysis membrane as reflected by significantly higher glucose dialysis retardation index. In starch–α-amylase system, MLP (4%) showed complete inhibition of starch digestion and glucose diffusion similar to that of acarbose till 120 min. Further, glucose diffusion was retarded to an extent of 83.7% and 63.5% by MLP (4%) at 180 and 240 min, respectively. On the other hand, MLP (2%) retarded glucose diffusion to an extent of 96%, 65%, and 51% at 120, 180, and 240 min respectively. Furthermore, molokhia leaf extract significantly enhanced uptake of glucose by rat hemidiaphragm in vitro. Conclusion: These findings conclusively demonstrate that the antidiabetic effect of molokhia leaves is mediated through delaying starch digestion and physical adsorption of liberated glucose limiting its diffusion across intestinal lumen and enhancing glucose uptake in peripheral tissues.

Journal of experimental psychology. Learning, memory, and cognition, Jan 19, 2018

It is commonly assumed that attention-demanding postencoding processes take place during the free... more It is commonly assumed that attention-demanding postencoding processes take place during the free time immediately following encoding of each memory item in a list. These processes are thought to prevent loss of information from working memory (WM). We tested whether interitem pauses during presentation of a list are used to focus attention (a) on the last-presented memory item or (b) on all items currently in WM, and (c) whether this changes over time. Here, we presented black probe letters between to-be-remembered red letters. Participants judged whether each probe letter corresponded to the last-presented memory item (last-item match group) or to any of the memory items presented up to that point in the list (any-item match group). To examine mnemonic processing as a function of time, the delay between the to-be-remembered letter and the following probe was manipulated in three experiments. When preprobe delays and interitem intervals were relatively short (Experiment 1), recall ...

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

Preface With changing global and health environment, discipline of Community Medicine (CM) needs ... more Preface With changing global and health environment, discipline of Community Medicine (CM) needs to be made more relevant to India’s need. This declaration is prepared to provide much-needed direction to the discipline and aims at strengthening the teaching of CM by creating better understanding of the discipline, its roles, scope, and functions of CM specialist; to the undergraduate and postgraduate students as well as the faculty of CM. It also aims to build the capacity of the CM department of medical colleges. This declaration is first in the series of activities planned by the Indian Association of Preventive and Social Medicine (IAPSM) core committee in this direction.

Language Variation and Change, 2017

This article examines the perception of the (ing) variants, [ɪŋ] and [ɪn], in three regionally di... more This article examines the perception of the (ing) variants, [ɪŋ] and [ɪn], in three regionally distinct localities in Britain: London in the South of England; Manchester in the North; and Edinburgh in Scotland. Data was gathered in perceptual tests in which respondents from each location rated stimuli doublets, each containing only one of the variants of (ing), on multiple social attribute scales. In London and Manchester, the perception of [ɪŋ] and [ɪn] broadly matches findings made for the United States in that speakers using [ɪŋ] are considered more articulate and hardworking, and less casual than speakers using [ɪn]. In Edinburgh, results are markedly different. We argue that these differences are due to a combination of factors that include the historical development of (ing) in a particular locale, which led to differences in production, variations in language ideology and, as a result, class-specific evaluations that appear to be regionally dependent.

Asian Pacific Journal of Tropical Medicine, 2016

In International Congress on Biocatalysis Hamburg Germany, 2002

Journal of Medicinal Plants Research, May 25, 2013

Eucalyptus tereticornis bark was screened for its anti-hyperglycemic potential by using In vitro ... more Eucalyptus tereticornis bark was screened for its anti-hyperglycemic potential by using In vitro assays viz. α-amylase, α-glycosidase and glucose adsorption. Dried powder of bark was used in glucose adsorption and alpha amylase assay, where as the water extract of the bark was used to study the inhibition of enteric enzymes (α-amylase, sucrose and α-glycosidase). The bark powder showed dose dependent amylase inhibition upto 3% sample concentration and further increase in concentration did not result in further inhibition, where as the water extract of the bark showed potent inhibition with IC50 value of 67.8 μg/mL. There was no notable activity observed in case of alpha-glycosidase assay. The enzyme sucrase was inhibited (35%) at 200 μg/ml extract concentration, with no further increases at higher concentrations. The bark powder showed glucose adsorption value of 1.32 mM at 10 mM glucose concentration and the adsorption increased with increase in the sample and glucose concentration...

Pakistan journal of pharmaceutical sciences

Present study evaluates the anti-hyperglycemic potential of two Indian spices Cinnamomum zeylanic... more Present study evaluates the anti-hyperglycemic potential of two Indian spices Cinnamomum zeylanicum(CZ) and Cumin cyminum(CC) (whole powder and aqueous extracts) using in vitro techniques like glucose adsorption assay, amylolysis kinetics and ex vivo assays like amylase, Sucrase and α-glucosidase assay. CZ displayed higher glucose adsorption and glucose diffusion retardation than CC, as shown by glucose adsorption and amylolysis kinetics assay. CZ showed lower inhibition of α-amylase and sucrase where as CC has no effect on both the enzymes. In case of α-glucosidase, CC had better inhibition than CZ. Further research is needed to understand the mechanism through which both the spices act to regulate the hyperglycemia.

Trigonella foenum-graecum (TFG) leaves are commonly consumed as a vegetable in India and it is al... more Trigonella foenum-graecum (TFG) leaves are commonly consumed as a vegetable in India and it is also known to possess potential health benefits. The present study was conduced to investigate antiulcer activity and possible antistress and antioxid-ant activities of methanol extract of Trigonella foenum-graecum leaves against cold restraint stress-induced ulcers in rats. Phytochemical screening of the extract show-ed the presence of fibers, flavonoids, polysaccharides, saponins, flavonoids, polysa-ccharides, fixed oils and some identified alkaloids viz., trigonelline and choline. Rats were pretreated with the extract (250 mg kg -1 p.o. and 500 mg kg -1 p.o) and the antiulcer effect was compared with omeprazole (10 mg kg -1 p.o.). TFG leaves trea-ted extract groups at both doses showed significant reduction in ulcer scoring indicating ulcer protection. Significant increase in serum glucose levels and signifi-cant decrease in serum cholesterol and triglyceride levels were obeseerved. Adr...

Pharmaceutical biology, Jan 9, 2015

Rhizophora mucronata Lam. (Rhizophoraceae), commonly known as Asiatic mangrove, has been used tra... more Rhizophora mucronata Lam. (Rhizophoraceae), commonly known as Asiatic mangrove, has been used traditionally among Asian countries as folk medicine. This study investigates the cholinesterase inhibitory potential and antioxidant activities of R. mucronata. Rhizophora mucronata leaves were successively extracted using solvents of varying polarity and a dosage of 100-500 µg/ml were used for each assay. Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities were assessed according to the method of Ellman. In vitro antioxidant activity was assessed using free radical scavenging, reducing power, and metal-chelating activity (duration - 3 months). Total phenolic and flavonoid content were quantified spectrophotometrically. Compound characterization was done using column chromatography, NMR, FTIR, and LC-MS analysis. Methanolic leaf extract (500 µg/ml) exhibited the highest inhibitory activity against AChE (92.73 ± 0.54%) and BuChE (98.98 ± 0.17%), with an IC50 v...

International Journal of Chemical and Analytical Science, 2013