Farhad Tabatabai Ghomsheh - Academia.edu (original) (raw)
Papers by Farhad Tabatabai Ghomsheh
Archives of Otolaryngology–Head & Neck Surgery, 2009
To investigate saccular function using vestibular evoked myogenic potentials in children with con... more To investigate saccular function using vestibular evoked myogenic potentials in children with congenital or early acquired sensorineural hearing loss.
Ṭibb-i tavānbakhshī, Nov 1, 2023
Background and Aims This study aimed to investigate the effect of exercises using fitness equipme... more Background and Aims This study aimed to investigate the effect of exercises using fitness equipment in parks on the lower limb muscle function of inactive women in Iran. Methods This is a prospective quasi-experimental study. The study population includes all inactive women in Tehran, Iran, aged 25-35 years. Of these, 40 women with no history of physical activity in the past year were selected using a convenience sampling method and randomly divided into two groups of control (n=20) and exercise (n=20). The training program consisted of workouts using fitness equipment in parks (sky walker, aero rider, and leg press machine) at 8 sessions, two sessions per week. The tests included Sargent jump test, triple jump test, star excursion balance test, and 6-meter single-leg timed hop test. The data were analyzed using descriptive statistics (mean and standard deviation), the Kolmogorov-Smirnov test (to examine the normal distribution of data), and the analysis of covariance (to examine differences in variables between the two groups) in SPSS software, version 24. Results After controlling the effect of pre-test scores, there was a significant difference between the two groups in the post-test score of the parameters of muscle function, indicating that exercises using the fitness equipment in parks can affect the lower limb muscle function of inactive women. Conclusion Exercises using park fitness equipment can be used to improve the lower limb muscle function of inactive women.
There are controversies among the researchers with respect to relationship between rate of force ... more There are controversies among the researchers with respect to relationship between rate of force development (RFD) and temporal variables. So the aim of this research was to determine relationship between temporal variables and RFD during block jump skill in junior volleyball players. Twenty one junior male volleyball players of national team participated in this study. Block jump, consisting of an eccentric phase following by an immediate concentric action was performed by participants. The temporal and RFD variables data for the best of three Block jumps were exported and analyzed with the force platform system (Kistler® force platform, 1000 Hz). Pearson product moment correlation coefficient (r) was employed for the analysis of the relationship between RFD and temporal parameters of block jump using SPSS software ver. 21 (p<0.05). The results showed that none of the variables have significant correlation with initiation phase and peak RFD of concentric phase. Eccentric phase showed correlation with concentric phase, average RFD of eccentric phase, peak RFD of eccentric phase, and peak RFD of eccentric phase and average RFD of eccentric phases well as average RFD of concentric phase. Concentric phase showed correlation with average RFD of eccentric. Average RFD of eccentric phase also presented correlation with peak RFD of eccentric phase and average RFD of concentric phase. Findings of the present study would be useful for volleyball trainers and coaches who desire to monitor and enhance their athletes' jump performance.
Biomedical Research-tokyo, 2016
Objectives: Because the function of the lower limb joints and the role of the trunk muscles in be... more Objectives: Because the function of the lower limb joints and the role of the trunk muscles in bearing and lifting loads are important, this study aimed to investigate the intervention of the initial body position when controlling inertia and its effect on the strategy of kinetic patterns in the lower limb joints as well as trunk muscle activity during symmetric lifting.Methods: This experimental study included 10 healthy young man. They were asked to lift an 8.4 Kg box at 3 different knee angles (-10, 35, and 70 degree angle of the thigh to the horizon line) symmetrically and at a constant velocity. The extensor moment and power of lower limb joints were calculated using the 3D linked-segment model (LSM). To measure the muscular activity of abdominal muscles (rectus abdominus (RA) and external oblique (EO)) and lumbar muscles (iliocostalis lumborum (IL) and multifidus (MU)), an 8 channel electromyogram (EMG) were used.Results: The results showed the similarity of extensor moment pa...
Frontiers in biomedical technologies, Jul 9, 2023
Purpose: Mathematical simulating and computer modeling of cells in organs help to better understa... more Purpose: Mathematical simulating and computer modeling of cells in organs help to better understand cells' interactions and tissues' functions. The purpose of this paper was to model and simulate the excitable membrane of gastric cells. In this simulation, the current physiological functional descriptions of the gastric cells have been used, and at the same time, the electrophysiological characteristics of similar cells in the gastrointestinal tract have also been considered. Materials and Methods: To obtain a mathematical model for the stomach Smooth Muscle Cells (SMCs), the properties and electrophysiological parameters from the SMCs in the colon were used in the simulation of the stomach SMCs. Using the sensitivity analysis method, the effective parameters and values for simulating the electrophysiological behavior of the excitable gastric cell membrane were obtained for different phases of slow-wave (such as Depolarization, Spike, Plateau, Repolarization, and Rest). Also, the Action Potential Duration (APDs) method in four modes of 10, 20, 50, and 90 percent of APDs was used to evaluate the estimation of the effect of sensitivity analysis on the slow-wave of the studied cells. Results: The findings showed that the greatest effect of the stimulation current parameters was on the slow-wave duration and frequency. In addition, the greatest effect of ion channel parameters was observed on the plateau_phase in the slow-wave. Based on these methods, the resulting slow-wave pattern and its frequency (2.8 cycles per min) were in line with the experimental observations for gastric SMCs. Conclusion: The mathematical model obtained from the model of colon SMCs accurately represented the electrophysiological behavior of the stomach cells.
Bulletin of Experimental Biology and Medicine, Aug 1, 2020
We analyzed the kinetic and kinematic variables of artificial tactile and artificial vibrotactile... more We analyzed the kinetic and kinematic variables of artificial tactile and artificial vibrotactile sensing test for mass detection in silicon phantom to determine tactile intensity and speed to obtain the best result in detecting the type and location of the mass. This study has utilized Artificial Tactile Sensing Instrument for Mass Detection (ATSIMD) in cylindrical silicone phantoms. The masses embedded in these samples were inserted in axial and environmental, deep and surface positions. The loading velocity, probe location, and the frequency of the applied force were considered as the independent variables in this study. It was found that for superficial mases the accuracy of detection at low speed 5 mm/sec, although dependent on the probe, but was 50% higher than under other conditions. For deep masses, with increasing mass depth, the accuracy of detection at medium speed of 8 mm/sec was 30% higher than at low speed. Mass detection by ATSIMD used in this study showed maximum efficiency at medium loading velocity. At low and high loading velocities, the dependence of mass detection on the probe location is related to the interaction of the testing method, tissue, and viscoelastic properties of the tissue.
Scientific Journal of Rehabilitation Medicine
Background and Aims Diabetes is associated with dysfunction and damage in various organs due to a... more Background and Aims Diabetes is associated with dysfunction and damage in various organs due to abnormal pressure on ten plantar regions. This study aims to compare the effect of offloading plantar pressure on peak pressure of ten plantar regions and gait speed in men with diabetes and active diabetic foot ulcers, and healthy men. Methods This is a causal-comparative study. Participants were 30 healthy men, 30 diabetic men and 30 men with active diabetic foot ulcers who needed no leg amputation according to their physicians. Sampling was done using random and convenience methods. Diabetic foot ulcers were classified based on the Meggitt-Wagner classification criteria, according to which grade 1 indicates grade 1 indicates a superficial ulcer and was used as a criterion for selecting people with diabetic foot ulcers. Plantar pressure variables were recorded using RSscan software (RSscan International, Belgium; 0.5×0.5×0.02 m, 4363 sensors) at a sampling frequency of 300 Hz and the ga...
Gene, cell and tissue, Feb 15, 2022
Background: The cell membrane acts as a filter, allowing ions to enter and leave the cell. Ionic ... more Background: The cell membrane acts as a filter, allowing ions to enter and leave the cell. Ionic channels are responsible for passing ions. This task is the responsibility of the ion channel gates, and ion transfer generates the action potential. Potassium channels play a prominent role in gastrointestinal smooth muscle cells and slow-wave production. Potassium channels are involved in acid secretion and gastric contraction. Gastric functional problems such as reflux disease and motility disorder are classified as electrophysiological disorders. Objectives: This study aimed to investigate the effect of potassium channel gates on the electrophysiology of the human gastric smooth muscle cells. Methods: Three states were considered for the potassium channels gate (Including physiological state, 50% blockage, and 90% blockage) to investigate the effect of the status of the gates, and a slow-wave diagram was obtained in these three states. Then, the value and the time of action potential were compared at five indicator points (initial potential, maximum spike potential, minimum valley potential, maximum plateau potential, and resting potential) in slow-wave. Results: The results showed that the maximum effect of the activation parameter of the potassium channel gate (τ d,Kni) was in 90% blockage compared to the physiological state, so that the maximum spike potential decreases by 2.43%. Also, a 90% blockage in the fast potassium channel gate inactivation parameter (τ f,Kf i) increased the maximum spike potential by 12.6% compared to the physiological state, while the minimum valley potential increased by 3%. In addition, the τ f,Kf i parameter reduced the time of occurrence of the maximum plateau potential by 7.9%. Conclusions: Potassium channels affect the slow-wave of the human gastric smooth muscle cell in spike, valley, and plateau phases. Using this method and blocking ion channels by pharmacological agents, the effect of ions in different phases of the slow-wave can be investigated. Also, it can help improve the contractile and motility disorders of the smooth muscles of the gastrointestinal tract.
2019 IEEE 16th International Conference on Rehabilitation Robotics (ICORR), 2019
Rehabilitative exercise for people suffering from upper limb impairments has the potential to imp... more Rehabilitative exercise for people suffering from upper limb impairments has the potential to improve their neuro-plasticity due to repetitive training. Our study investigates the usefulness of Electroencephalogram and Electromyogram (EMG) signals for incorporation in humanrobot interaction loop. Twenty healthy participants recruited who performed a series of physical and cognitive tasks, with an inherent fatiguing component in those tasks. Here we report observed effects on EMG signals. Participants performed a Biceps curl repetitions using a suitable dumbbell in three phases. In phase 1, the initial weight was set to achieve maximum voluntary contraction (MVC). Phase 2 followed with 80 % MVC and phase 3 had 60% MVC. After each phase, they had a break around 3 minutes. EMG data were acquired from Biceps, Triceps, and Brachioradialis muscles. Different EMG features were explored to inform on muscle fatigue during this interaction. Comparing EMG during the first and last dumbbell of each phase demonstrated that the muscle fatigue had caused an increase in the average power (94% of cases) and amplitude (91%) and a decrease in the mean (80%) and the median frequency (57%) of EMG, which was more noticeable in Biceps. The results from integrated EMG showed a continuous rise in all three muscles which was more pronounced in Biceps muscle. Given these results, we identify EMG average power as the most reliable feature for informing on muscle fatigue.
Introduction: Appropriateness of ergonomic properties of outdoor fitness equipment with respect t... more Introduction: Appropriateness of ergonomic properties of outdoor fitness equipment with respect to anthropometric features of their users can reduce risk of injuries. The aim of this study was to investigate the appropriateness of the ergonomic indices of outdoor leg presses, chest presses, and pull chair machines with respect to anthropometric parameters in Iranian female athlete users. Material and Methods: 124 Iranian female athletes who used outdoor fitness machines in Iran were recruited. An engineering tape measure and an anthropometric kit were used to measure the dimensions of the chest press, leg press, pull chair machines and also anthropometry of female users. Next, using the anthropometric data and the fitness device standards based on trigonometric calculations, standard anthropometric computational dimensions of devices were obtained. Standard indices of outdoor fitness devices based on athlete’s anthropometric data were compared with the dimensions of outdoor fitness ...
In this study, an investigation was done in order to increase stability of ankle and reduce injur... more In this study, an investigation was done in order to increase stability of ankle and reduce injuries resulting twist while using aid orthosis and effort in providing superior samples. Therefore this study aims to investigate the effect of ankle hinged Stirrup brace on the Sagittal position of ankle joint in healthy individuals. Eighteen healthy subjects participated in this quasi-experimental study (8 males, 10 females) aged 19 to 30 years. Individuals were selected by non-random sampling and accessible sampling type based on inclusion criteria. Dorsiflexion angle at the moment of heel contact with the ground while walking in the 3 different steps of test with just shoes, shoes with articulated Stirrup brace, shoes with modified articulated Stirrup brace (stretch strep) was recorded by using (VICON Motion Systems) motion analysis system. For comparison of the supposed positions also paired t test was used. Articulated ankle brace have no significant effect on the ankle joint sagitta...
Introduction: Since the use of medical insole is recommended as one of the strategies to deal wit... more Introduction: Since the use of medical insole is recommended as one of the strategies to deal with the potential for joint injuries, Flatfoot is one of the most common abnormalities in body structure that Due to the decrease in the height of the medial longitudinal arch of the foot and its functional defect, the increases risk of joint damage due to changes in the transfer of ground reaction forces. One of the treatment options that is suggested is the use of a medical insole. The purpose of this study was to investigate the effect of two different forms of silicone insoles on the peak of the ground reaction force, loading rate and time to stability in the landing-jumping-landing skill of active young women with flat foot. Materials and methods: 28 women with a history of regular activity exercise were divided into two groups of 14 (flat foot and normal foot). The subjects landed two legs on a level with a height of 0.5 m on the forwards of the first force plate, jumped without stop...
Work, 2021
BACKGROUND: Nowadays, although using laptops to perform many routine activities is inevitable, ma... more BACKGROUND: Nowadays, although using laptops to perform many routine activities is inevitable, many wheelchair users are not able to efficiently use their laptops due to their movement limitations and inappropriate workstations. OBJECTIVE: The purpose of this study was to design and evaluate a novel ergonomic laptop desk for wheelchair users by considering their movement limitations. METHODS: In this experimental study, we ergonomically designed and assessed a novel laptop desk in two phases in a laboratory. In the first phase of the study, design specifications were identified by an expert panel and, accordingly, a new laptop desk was designed and prototyped for the wheelchair users. In the second phase, in order to evaluate the laptop desk, 14 wheelchair users were asked to complete a typing task within 20 minutes, both with and without using the laptop desk. Postural risk level, perceived discomfort, and task performance were evaluated using the Rapid Upper Limb Assessment (RULA)...
Journal of Biomechanics, 2021
The purpose of this study is to model the electrophysiological behavior of excitable membrane and... more The purpose of this study is to model the electrophysiological behavior of excitable membrane and wavefront propagation in the Stomach Wall in physiological and pharmacological states. The propagation of this wave is based on cellular electrophysiological activity and ionic channel properties. In this study, we arranged the stomach wall cells together using the Gap Junctions approach. Slow wave is generated by gastric pacemaker cells. This wave propagates via the interaction of cells with each other throughout the stomach wall. Potassium currents are one of the main factors in regulating the pattern of wavefront propagation. To investigate the effect of limiting the exchange of potassium currents from cell membranes, 10%, 50%, 90%, and complete blockade were applied on both non-inactivating potassium current (IKni) and fast-inactivating potassium current (IKfi). The results show that IKniion channel blockage has a considerable effect on the plateau phase in the propagation of the excitation wave. The maximum value of the action potential in the plateau phase in the excitation wave with complete obstruction from -40.92 mV in the physiological state reached -18.97 mV, which is about 54% higher than the physiological state. Also, compared to the physiological state, complete blockage of the I_Kfi causes a 15% increase in the slow-wave spike phase (from -36.72 mV to -31.36 mV). Using this model, the effect of ions in different phases of slow-wave can be investigated. In addition, by blocking ion channels, functional disorders and smooth muscle contraction can be improved.
International Clinical Neuroscience Journal, 2020
Background: Early detection of prostate cancer has significant benefits for its treatment and can... more Background: Early detection of prostate cancer has significant benefits for its treatment and can increase the survival chance in patients. In recent years, new methods such as shear wave elastography and vibro-elastography, as well as artificial tactile sensing, have been used to detect a mass in the prostate tissue in-vivo and ex-vivo. This paper aims to investigate the difference between normal and malignant prostate tissue reaction to simple and vibro-neural stimulation for prostate tissue mass detection in order to determine neural stimulation intensity, velocity, and frequency to obtain the best result in detecting the type and location of the tumor. Methods: This study has utilized neural stimulation devices in normal and cancerous tissues. The stimulation velocity, probe location, and the frequency of neural stimulation considered as the independent variables. Results: The results show that for superficial masses, although dependent on the probe, the accuracy of detection at...
Iranian Rehabilitation Journal, 2018
The result of auditory brainstem response is used worldwide for detecting hearing impairments or ... more The result of auditory brainstem response is used worldwide for detecting hearing impairments or hearing aids. This study aimed to introduce the superiority of mathematical innovation algorithm toward subjective evaluation by an audiologist. The automatic algorithm method is encouraged for detecting the waves of Auditory Brainstem Response (ABR), because it can reduce subjective evaluation biases and visual analysis errors. This article portrays another technique for automatic detection of the peaks. Finally, by obtaining the standard pattern with this automatic algorithm for Persian speakers, we will compare it with the English speakers whose information was obtained by subjective method in Northwestern University. This article describes the effect of different factors on brainstem responses by performing a new automatic method. Methods: Auditory evoked potentials of brainstem activity were recorded by Electro encephalogram (EEG) of 27 Persian speaker adults with normal hearing. Three stimulus /ga/, / da/, and /ba/ were presented. This strategy depends on the utilization of reference wave forms, time latencies, and peaks adjusted and comparison with the ABR. Brainstem response latencies of brainstem peaks were extracted by the automatic method in temporal and spectral domains. This step provides language patterns for Persian speakers. Finally, the results of Persian speakers were compared with the results of a previous study done in Northwestern University by the same recording protocol as our own study on 22 English speaker children. Intraclass correlation coefficients and paired t test were used for evaluating and comparing the results. Results: According to the results, the performance of automatic method is high and reliable. Automatic and visual analysis methods had significant interaction. Latency of auditory brainstem response to the same stimulus in the two study groups was different and had a significant latency. The significance of these discoveries and clinical outcomes of this target strategy are featured in this paper. Discussion: This simple innovative algorithm could find the correct location of ABR peaks. Because of different acoustic signs and symptoms in the brainstem, the time latencies for all three stimulus used in this study are completely different.
Objective: Aim of this study was to analysis the ankle momentangle relation and its characteristi... more Objective: Aim of this study was to analysis the ankle momentangle relation and its characteristics at different gait speeds and phases for using in prosthetic ankle-foot design. Materials & Methods: This was a cross-sectional analytic study in which 20 participants were chosen with assessable sampling method. Gait analysis at different speeds was performed with two force-plates and five high speed cameras. Ankle characteristics including quasi-stiffness and work were estimated at three periods of stance phase based on moment-angle loop. Mean differences were analyzed with repeated measure ANOVA and regression analysis was performed to fit the linear model to the data. Results: Moment-angle curve was clockwise at slower speeds and turned counterclockwise while speed increased. The best fitted line to the work-walking speed curve had R2= 0.81. There were significant differences in quasi-stiffness between fast and normal speed and slower speeds (p<0.001). Conclusion: Moment-angle curve displayed ankle passive function in slower speeds and active function in faster speeds. Results showed ankle characteristics varied at different gait phases and speeds. Thus, at slower speeds a spring-damper model with regulable damping would simulate the ankle function. However, at higher speeds the active elements also should be considered.
Surgical Innovation, 2020
Background. Surgical hand scrub is strongly recommended as an essential measure to reduce surgica... more Background. Surgical hand scrub is strongly recommended as an essential measure to reduce surgical site infections (SSIs). SSI results in morbidity and additional cost. Micropunctures may occur on surgical gloves during operation, thus hand scrub cannot be omitted in any condition. Generally speaking, the adequacy of hand scrub is decided by the surgeon. Only occasionally, surveillance of hygienic status of hands is performed after scrub. Therefore, the potential exists that suboptimal handwash leads to SSIs. There are standards for preoperative handwash, but all of them are operator dependent, and continuous surveillance is actually impossible. One solution is to omit the role of surgeon in handwashing. This can be achieved by designing a standard procedure, performed mechanically by a machine, considering the detailed requirements of hygienic surgical hand scrub. The goal of this study was to develop a procedure that works on the design, fabrication, and trial of a new handwashing...
Informatics in Medicine Unlocked
Archives of Otolaryngology–Head & Neck Surgery, 2009
To investigate saccular function using vestibular evoked myogenic potentials in children with con... more To investigate saccular function using vestibular evoked myogenic potentials in children with congenital or early acquired sensorineural hearing loss.
Ṭibb-i tavānbakhshī, Nov 1, 2023
Background and Aims This study aimed to investigate the effect of exercises using fitness equipme... more Background and Aims This study aimed to investigate the effect of exercises using fitness equipment in parks on the lower limb muscle function of inactive women in Iran. Methods This is a prospective quasi-experimental study. The study population includes all inactive women in Tehran, Iran, aged 25-35 years. Of these, 40 women with no history of physical activity in the past year were selected using a convenience sampling method and randomly divided into two groups of control (n=20) and exercise (n=20). The training program consisted of workouts using fitness equipment in parks (sky walker, aero rider, and leg press machine) at 8 sessions, two sessions per week. The tests included Sargent jump test, triple jump test, star excursion balance test, and 6-meter single-leg timed hop test. The data were analyzed using descriptive statistics (mean and standard deviation), the Kolmogorov-Smirnov test (to examine the normal distribution of data), and the analysis of covariance (to examine differences in variables between the two groups) in SPSS software, version 24. Results After controlling the effect of pre-test scores, there was a significant difference between the two groups in the post-test score of the parameters of muscle function, indicating that exercises using the fitness equipment in parks can affect the lower limb muscle function of inactive women. Conclusion Exercises using park fitness equipment can be used to improve the lower limb muscle function of inactive women.
There are controversies among the researchers with respect to relationship between rate of force ... more There are controversies among the researchers with respect to relationship between rate of force development (RFD) and temporal variables. So the aim of this research was to determine relationship between temporal variables and RFD during block jump skill in junior volleyball players. Twenty one junior male volleyball players of national team participated in this study. Block jump, consisting of an eccentric phase following by an immediate concentric action was performed by participants. The temporal and RFD variables data for the best of three Block jumps were exported and analyzed with the force platform system (Kistler® force platform, 1000 Hz). Pearson product moment correlation coefficient (r) was employed for the analysis of the relationship between RFD and temporal parameters of block jump using SPSS software ver. 21 (p<0.05). The results showed that none of the variables have significant correlation with initiation phase and peak RFD of concentric phase. Eccentric phase showed correlation with concentric phase, average RFD of eccentric phase, peak RFD of eccentric phase, and peak RFD of eccentric phase and average RFD of eccentric phases well as average RFD of concentric phase. Concentric phase showed correlation with average RFD of eccentric. Average RFD of eccentric phase also presented correlation with peak RFD of eccentric phase and average RFD of concentric phase. Findings of the present study would be useful for volleyball trainers and coaches who desire to monitor and enhance their athletes' jump performance.
Biomedical Research-tokyo, 2016
Objectives: Because the function of the lower limb joints and the role of the trunk muscles in be... more Objectives: Because the function of the lower limb joints and the role of the trunk muscles in bearing and lifting loads are important, this study aimed to investigate the intervention of the initial body position when controlling inertia and its effect on the strategy of kinetic patterns in the lower limb joints as well as trunk muscle activity during symmetric lifting.Methods: This experimental study included 10 healthy young man. They were asked to lift an 8.4 Kg box at 3 different knee angles (-10, 35, and 70 degree angle of the thigh to the horizon line) symmetrically and at a constant velocity. The extensor moment and power of lower limb joints were calculated using the 3D linked-segment model (LSM). To measure the muscular activity of abdominal muscles (rectus abdominus (RA) and external oblique (EO)) and lumbar muscles (iliocostalis lumborum (IL) and multifidus (MU)), an 8 channel electromyogram (EMG) were used.Results: The results showed the similarity of extensor moment pa...
Frontiers in biomedical technologies, Jul 9, 2023
Purpose: Mathematical simulating and computer modeling of cells in organs help to better understa... more Purpose: Mathematical simulating and computer modeling of cells in organs help to better understand cells' interactions and tissues' functions. The purpose of this paper was to model and simulate the excitable membrane of gastric cells. In this simulation, the current physiological functional descriptions of the gastric cells have been used, and at the same time, the electrophysiological characteristics of similar cells in the gastrointestinal tract have also been considered. Materials and Methods: To obtain a mathematical model for the stomach Smooth Muscle Cells (SMCs), the properties and electrophysiological parameters from the SMCs in the colon were used in the simulation of the stomach SMCs. Using the sensitivity analysis method, the effective parameters and values for simulating the electrophysiological behavior of the excitable gastric cell membrane were obtained for different phases of slow-wave (such as Depolarization, Spike, Plateau, Repolarization, and Rest). Also, the Action Potential Duration (APDs) method in four modes of 10, 20, 50, and 90 percent of APDs was used to evaluate the estimation of the effect of sensitivity analysis on the slow-wave of the studied cells. Results: The findings showed that the greatest effect of the stimulation current parameters was on the slow-wave duration and frequency. In addition, the greatest effect of ion channel parameters was observed on the plateau_phase in the slow-wave. Based on these methods, the resulting slow-wave pattern and its frequency (2.8 cycles per min) were in line with the experimental observations for gastric SMCs. Conclusion: The mathematical model obtained from the model of colon SMCs accurately represented the electrophysiological behavior of the stomach cells.
Bulletin of Experimental Biology and Medicine, Aug 1, 2020
We analyzed the kinetic and kinematic variables of artificial tactile and artificial vibrotactile... more We analyzed the kinetic and kinematic variables of artificial tactile and artificial vibrotactile sensing test for mass detection in silicon phantom to determine tactile intensity and speed to obtain the best result in detecting the type and location of the mass. This study has utilized Artificial Tactile Sensing Instrument for Mass Detection (ATSIMD) in cylindrical silicone phantoms. The masses embedded in these samples were inserted in axial and environmental, deep and surface positions. The loading velocity, probe location, and the frequency of the applied force were considered as the independent variables in this study. It was found that for superficial mases the accuracy of detection at low speed 5 mm/sec, although dependent on the probe, but was 50% higher than under other conditions. For deep masses, with increasing mass depth, the accuracy of detection at medium speed of 8 mm/sec was 30% higher than at low speed. Mass detection by ATSIMD used in this study showed maximum efficiency at medium loading velocity. At low and high loading velocities, the dependence of mass detection on the probe location is related to the interaction of the testing method, tissue, and viscoelastic properties of the tissue.
Scientific Journal of Rehabilitation Medicine
Background and Aims Diabetes is associated with dysfunction and damage in various organs due to a... more Background and Aims Diabetes is associated with dysfunction and damage in various organs due to abnormal pressure on ten plantar regions. This study aims to compare the effect of offloading plantar pressure on peak pressure of ten plantar regions and gait speed in men with diabetes and active diabetic foot ulcers, and healthy men. Methods This is a causal-comparative study. Participants were 30 healthy men, 30 diabetic men and 30 men with active diabetic foot ulcers who needed no leg amputation according to their physicians. Sampling was done using random and convenience methods. Diabetic foot ulcers were classified based on the Meggitt-Wagner classification criteria, according to which grade 1 indicates grade 1 indicates a superficial ulcer and was used as a criterion for selecting people with diabetic foot ulcers. Plantar pressure variables were recorded using RSscan software (RSscan International, Belgium; 0.5×0.5×0.02 m, 4363 sensors) at a sampling frequency of 300 Hz and the ga...
Gene, cell and tissue, Feb 15, 2022
Background: The cell membrane acts as a filter, allowing ions to enter and leave the cell. Ionic ... more Background: The cell membrane acts as a filter, allowing ions to enter and leave the cell. Ionic channels are responsible for passing ions. This task is the responsibility of the ion channel gates, and ion transfer generates the action potential. Potassium channels play a prominent role in gastrointestinal smooth muscle cells and slow-wave production. Potassium channels are involved in acid secretion and gastric contraction. Gastric functional problems such as reflux disease and motility disorder are classified as electrophysiological disorders. Objectives: This study aimed to investigate the effect of potassium channel gates on the electrophysiology of the human gastric smooth muscle cells. Methods: Three states were considered for the potassium channels gate (Including physiological state, 50% blockage, and 90% blockage) to investigate the effect of the status of the gates, and a slow-wave diagram was obtained in these three states. Then, the value and the time of action potential were compared at five indicator points (initial potential, maximum spike potential, minimum valley potential, maximum plateau potential, and resting potential) in slow-wave. Results: The results showed that the maximum effect of the activation parameter of the potassium channel gate (τ d,Kni) was in 90% blockage compared to the physiological state, so that the maximum spike potential decreases by 2.43%. Also, a 90% blockage in the fast potassium channel gate inactivation parameter (τ f,Kf i) increased the maximum spike potential by 12.6% compared to the physiological state, while the minimum valley potential increased by 3%. In addition, the τ f,Kf i parameter reduced the time of occurrence of the maximum plateau potential by 7.9%. Conclusions: Potassium channels affect the slow-wave of the human gastric smooth muscle cell in spike, valley, and plateau phases. Using this method and blocking ion channels by pharmacological agents, the effect of ions in different phases of the slow-wave can be investigated. Also, it can help improve the contractile and motility disorders of the smooth muscles of the gastrointestinal tract.
2019 IEEE 16th International Conference on Rehabilitation Robotics (ICORR), 2019
Rehabilitative exercise for people suffering from upper limb impairments has the potential to imp... more Rehabilitative exercise for people suffering from upper limb impairments has the potential to improve their neuro-plasticity due to repetitive training. Our study investigates the usefulness of Electroencephalogram and Electromyogram (EMG) signals for incorporation in humanrobot interaction loop. Twenty healthy participants recruited who performed a series of physical and cognitive tasks, with an inherent fatiguing component in those tasks. Here we report observed effects on EMG signals. Participants performed a Biceps curl repetitions using a suitable dumbbell in three phases. In phase 1, the initial weight was set to achieve maximum voluntary contraction (MVC). Phase 2 followed with 80 % MVC and phase 3 had 60% MVC. After each phase, they had a break around 3 minutes. EMG data were acquired from Biceps, Triceps, and Brachioradialis muscles. Different EMG features were explored to inform on muscle fatigue during this interaction. Comparing EMG during the first and last dumbbell of each phase demonstrated that the muscle fatigue had caused an increase in the average power (94% of cases) and amplitude (91%) and a decrease in the mean (80%) and the median frequency (57%) of EMG, which was more noticeable in Biceps. The results from integrated EMG showed a continuous rise in all three muscles which was more pronounced in Biceps muscle. Given these results, we identify EMG average power as the most reliable feature for informing on muscle fatigue.
Introduction: Appropriateness of ergonomic properties of outdoor fitness equipment with respect t... more Introduction: Appropriateness of ergonomic properties of outdoor fitness equipment with respect to anthropometric features of their users can reduce risk of injuries. The aim of this study was to investigate the appropriateness of the ergonomic indices of outdoor leg presses, chest presses, and pull chair machines with respect to anthropometric parameters in Iranian female athlete users. Material and Methods: 124 Iranian female athletes who used outdoor fitness machines in Iran were recruited. An engineering tape measure and an anthropometric kit were used to measure the dimensions of the chest press, leg press, pull chair machines and also anthropometry of female users. Next, using the anthropometric data and the fitness device standards based on trigonometric calculations, standard anthropometric computational dimensions of devices were obtained. Standard indices of outdoor fitness devices based on athlete’s anthropometric data were compared with the dimensions of outdoor fitness ...
In this study, an investigation was done in order to increase stability of ankle and reduce injur... more In this study, an investigation was done in order to increase stability of ankle and reduce injuries resulting twist while using aid orthosis and effort in providing superior samples. Therefore this study aims to investigate the effect of ankle hinged Stirrup brace on the Sagittal position of ankle joint in healthy individuals. Eighteen healthy subjects participated in this quasi-experimental study (8 males, 10 females) aged 19 to 30 years. Individuals were selected by non-random sampling and accessible sampling type based on inclusion criteria. Dorsiflexion angle at the moment of heel contact with the ground while walking in the 3 different steps of test with just shoes, shoes with articulated Stirrup brace, shoes with modified articulated Stirrup brace (stretch strep) was recorded by using (VICON Motion Systems) motion analysis system. For comparison of the supposed positions also paired t test was used. Articulated ankle brace have no significant effect on the ankle joint sagitta...
Introduction: Since the use of medical insole is recommended as one of the strategies to deal wit... more Introduction: Since the use of medical insole is recommended as one of the strategies to deal with the potential for joint injuries, Flatfoot is one of the most common abnormalities in body structure that Due to the decrease in the height of the medial longitudinal arch of the foot and its functional defect, the increases risk of joint damage due to changes in the transfer of ground reaction forces. One of the treatment options that is suggested is the use of a medical insole. The purpose of this study was to investigate the effect of two different forms of silicone insoles on the peak of the ground reaction force, loading rate and time to stability in the landing-jumping-landing skill of active young women with flat foot. Materials and methods: 28 women with a history of regular activity exercise were divided into two groups of 14 (flat foot and normal foot). The subjects landed two legs on a level with a height of 0.5 m on the forwards of the first force plate, jumped without stop...
Work, 2021
BACKGROUND: Nowadays, although using laptops to perform many routine activities is inevitable, ma... more BACKGROUND: Nowadays, although using laptops to perform many routine activities is inevitable, many wheelchair users are not able to efficiently use their laptops due to their movement limitations and inappropriate workstations. OBJECTIVE: The purpose of this study was to design and evaluate a novel ergonomic laptop desk for wheelchair users by considering their movement limitations. METHODS: In this experimental study, we ergonomically designed and assessed a novel laptop desk in two phases in a laboratory. In the first phase of the study, design specifications were identified by an expert panel and, accordingly, a new laptop desk was designed and prototyped for the wheelchair users. In the second phase, in order to evaluate the laptop desk, 14 wheelchair users were asked to complete a typing task within 20 minutes, both with and without using the laptop desk. Postural risk level, perceived discomfort, and task performance were evaluated using the Rapid Upper Limb Assessment (RULA)...
Journal of Biomechanics, 2021
The purpose of this study is to model the electrophysiological behavior of excitable membrane and... more The purpose of this study is to model the electrophysiological behavior of excitable membrane and wavefront propagation in the Stomach Wall in physiological and pharmacological states. The propagation of this wave is based on cellular electrophysiological activity and ionic channel properties. In this study, we arranged the stomach wall cells together using the Gap Junctions approach. Slow wave is generated by gastric pacemaker cells. This wave propagates via the interaction of cells with each other throughout the stomach wall. Potassium currents are one of the main factors in regulating the pattern of wavefront propagation. To investigate the effect of limiting the exchange of potassium currents from cell membranes, 10%, 50%, 90%, and complete blockade were applied on both non-inactivating potassium current (IKni) and fast-inactivating potassium current (IKfi). The results show that IKniion channel blockage has a considerable effect on the plateau phase in the propagation of the excitation wave. The maximum value of the action potential in the plateau phase in the excitation wave with complete obstruction from -40.92 mV in the physiological state reached -18.97 mV, which is about 54% higher than the physiological state. Also, compared to the physiological state, complete blockage of the I_Kfi causes a 15% increase in the slow-wave spike phase (from -36.72 mV to -31.36 mV). Using this model, the effect of ions in different phases of slow-wave can be investigated. In addition, by blocking ion channels, functional disorders and smooth muscle contraction can be improved.
International Clinical Neuroscience Journal, 2020
Background: Early detection of prostate cancer has significant benefits for its treatment and can... more Background: Early detection of prostate cancer has significant benefits for its treatment and can increase the survival chance in patients. In recent years, new methods such as shear wave elastography and vibro-elastography, as well as artificial tactile sensing, have been used to detect a mass in the prostate tissue in-vivo and ex-vivo. This paper aims to investigate the difference between normal and malignant prostate tissue reaction to simple and vibro-neural stimulation for prostate tissue mass detection in order to determine neural stimulation intensity, velocity, and frequency to obtain the best result in detecting the type and location of the tumor. Methods: This study has utilized neural stimulation devices in normal and cancerous tissues. The stimulation velocity, probe location, and the frequency of neural stimulation considered as the independent variables. Results: The results show that for superficial masses, although dependent on the probe, the accuracy of detection at...
Iranian Rehabilitation Journal, 2018
The result of auditory brainstem response is used worldwide for detecting hearing impairments or ... more The result of auditory brainstem response is used worldwide for detecting hearing impairments or hearing aids. This study aimed to introduce the superiority of mathematical innovation algorithm toward subjective evaluation by an audiologist. The automatic algorithm method is encouraged for detecting the waves of Auditory Brainstem Response (ABR), because it can reduce subjective evaluation biases and visual analysis errors. This article portrays another technique for automatic detection of the peaks. Finally, by obtaining the standard pattern with this automatic algorithm for Persian speakers, we will compare it with the English speakers whose information was obtained by subjective method in Northwestern University. This article describes the effect of different factors on brainstem responses by performing a new automatic method. Methods: Auditory evoked potentials of brainstem activity were recorded by Electro encephalogram (EEG) of 27 Persian speaker adults with normal hearing. Three stimulus /ga/, / da/, and /ba/ were presented. This strategy depends on the utilization of reference wave forms, time latencies, and peaks adjusted and comparison with the ABR. Brainstem response latencies of brainstem peaks were extracted by the automatic method in temporal and spectral domains. This step provides language patterns for Persian speakers. Finally, the results of Persian speakers were compared with the results of a previous study done in Northwestern University by the same recording protocol as our own study on 22 English speaker children. Intraclass correlation coefficients and paired t test were used for evaluating and comparing the results. Results: According to the results, the performance of automatic method is high and reliable. Automatic and visual analysis methods had significant interaction. Latency of auditory brainstem response to the same stimulus in the two study groups was different and had a significant latency. The significance of these discoveries and clinical outcomes of this target strategy are featured in this paper. Discussion: This simple innovative algorithm could find the correct location of ABR peaks. Because of different acoustic signs and symptoms in the brainstem, the time latencies for all three stimulus used in this study are completely different.
Objective: Aim of this study was to analysis the ankle momentangle relation and its characteristi... more Objective: Aim of this study was to analysis the ankle momentangle relation and its characteristics at different gait speeds and phases for using in prosthetic ankle-foot design. Materials & Methods: This was a cross-sectional analytic study in which 20 participants were chosen with assessable sampling method. Gait analysis at different speeds was performed with two force-plates and five high speed cameras. Ankle characteristics including quasi-stiffness and work were estimated at three periods of stance phase based on moment-angle loop. Mean differences were analyzed with repeated measure ANOVA and regression analysis was performed to fit the linear model to the data. Results: Moment-angle curve was clockwise at slower speeds and turned counterclockwise while speed increased. The best fitted line to the work-walking speed curve had R2= 0.81. There were significant differences in quasi-stiffness between fast and normal speed and slower speeds (p<0.001). Conclusion: Moment-angle curve displayed ankle passive function in slower speeds and active function in faster speeds. Results showed ankle characteristics varied at different gait phases and speeds. Thus, at slower speeds a spring-damper model with regulable damping would simulate the ankle function. However, at higher speeds the active elements also should be considered.
Surgical Innovation, 2020
Background. Surgical hand scrub is strongly recommended as an essential measure to reduce surgica... more Background. Surgical hand scrub is strongly recommended as an essential measure to reduce surgical site infections (SSIs). SSI results in morbidity and additional cost. Micropunctures may occur on surgical gloves during operation, thus hand scrub cannot be omitted in any condition. Generally speaking, the adequacy of hand scrub is decided by the surgeon. Only occasionally, surveillance of hygienic status of hands is performed after scrub. Therefore, the potential exists that suboptimal handwash leads to SSIs. There are standards for preoperative handwash, but all of them are operator dependent, and continuous surveillance is actually impossible. One solution is to omit the role of surgeon in handwashing. This can be achieved by designing a standard procedure, performed mechanically by a machine, considering the detailed requirements of hygienic surgical hand scrub. The goal of this study was to develop a procedure that works on the design, fabrication, and trial of a new handwashing...
Informatics in Medicine Unlocked