Fariba Bayat - Academia.edu (original) (raw)
Papers by Fariba Bayat
The Journal of Tehran University Heart Center, Sep 7, 2019
Clinical Case Reports, 2022
Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch ar... more Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch arteries. Here, we describe an atypical presentation of the disease with heart failure.
Iranian Heart Journal, Apr 1, 2021
Clinical Case Reports, 2022
Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch ar... more Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch arteries. Here, we describe an atypical presentation of the disease with heart failure.
Emergency, 2018
Patent foramen ovale (PFO) is usually asymptomatic; however, it could be quite dangerous for pati... more Patent foramen ovale (PFO) is usually asymptomatic; however, it could be quite dangerous for patients with right side clot in which thrombus can transmit the PFO and paradoxically emboli to systemic circulation. Here we present a patient with ankle fracture and paradoxical embolus to the brain, who was successfully treated with emergent thrombectomy, inferior vena cava (IVC) filter placement and anticoagulation therapy. Despite the high rate of mortality in these patients, fortunately our patient survived with surgical treatment.
International Journal of Computer Assisted Radiology and Surgery, 2021
Cardiac multimodal image fusion can offer an image with various types of information in a single ... more Cardiac multimodal image fusion can offer an image with various types of information in a single image. Many coronary stenosis, which are anatomically clear, are not functionally significant. The treatment of such kind of stenosis can cause irreversible effects on the patient. Thus, choosing the best treatment planning depend on anatomical and functional information is very beneficial. An algorithm for the fusion of coronary computed tomography angiography (CCTA) as an anatomical and transthoracic echocardiography (TTE) as a functional modality is presented. CCTA and TTE are temporally registered using manifold learning. A pattern search optimization algorithm, using normalized mutual information, is used to find the best match slice to TTE frame from CCTA volume. By employing a free-form deformation, the heart's non-rigid deformations are modeled. The spatiotemporal registered TTE frame is embedded to achieve the fusion result. The accuracy is evaluated on CCTA and TTE data obt...
Introduction: Coronary Artery Disease (CAD) is the most common cause for left ventricular dysfunc... more Introduction: Coronary Artery Disease (CAD) is the most common cause for left ventricular dysfunction. Unfortunately, the treatment strategies of regional myocardial diastolic dysfunction in patients with CAD have not been well characterized and benefit of Percutaneous Coronary Intervention (PCI) as a treatment strategy is not clear. So the present study aimed to assess the effects of PCI on isolated left ventricular diastolic dysfunction in patients with CAD by using Strain Rate (SR) imaging. Methods: Thirty adult patients with coronary artery disease candidate for PCI on left anterior descending artery were enrolled to our study. Echocardiographic finding and early diastolic SR was measured before and 48 hours after PCI. Results: Mean age of the patients was 59.9±8.3 years. All of the left ventricular diastolic parameters showed significant difference before and after elective PCI; while pulmonary vein flow before and after PCI did not show any significant differences by using McN...
Frontiers in Biomedical Technologies, 2021
Purpose: Multimodal Cardiac Image (MCI) registration is one of the evolving fields in the diagnos... more Purpose: Multimodal Cardiac Image (MCI) registration is one of the evolving fields in the diagnostic methods of Cardiovascular Diseases (CVDs). Since the heart has nonlinear and dynamic behavior, Temporal Registration (TR) is the fundamental step for the spatial registration and fusion of MCIs to integrate the heart's anatomical and functional information into a single and more informative display. Therefore, in this study, a TR framework is proposed to align MCIs in the same cardiac phase. Materials and Methods: A manifold learning-based method is proposed for the TR of MCIs. The Euclidean distance among consecutive samples lying on the Locally Linear Embedding (LLE) of MCIs is computed. By considering cardiac volume pattern concepts from distance plots of LLEs, six cardiac phases (end-diastole, rapid-ejection, end-systole, rapid-filling, reduced-filling, and atrial-contraction) are temporally registered. Results: The validation of the proposed method proceeds by collecting the...
The Journal of Tehran University Heart Center, 2021
Tricuspid valve myxomas are very uncommon tumors that could be found after the occurrence of pu... more Tricuspid valve myxomas are very uncommon tumors that could be found after the occurrence of pulmonary thromboembolism, symptomatic tricuspid obstruction, and right-sided heart failure. Herein, we describe a 42-year-old woman evaluated for an abdominal mass. In preoperative consultation, a tricuspid valve mass was detected in echocardiography. She underwent the removal of a benign uterine myoma and a myxoma of the tricuspid valve. Tricuspid valve myxomas constitute a scarce diagnosis. They could be asymptomatic, occurring in unusual locations and in association with benign tumors in other organs. Our patient was asymptomatic, underscoring the significance of the early diagnosis of this type of tumor to prevent further catastrophic events.
The Journal of Tehran University Heart Center, 2019
Background: Bariatric surgery is efficiently associated with the long-term resolution of obesity ... more Background: Bariatric surgery is efficiently associated with the long-term resolution of obesity and its related morbidities. Not only can this surgical modality improve the metabolic profile, diastolic and systolic cardiac functions, and the clinical symptoms of heart failure or cardiomyopathy, but it can also reduce the atherosclerosis risk, ventricular mass, and pericardial fat thickness. The aim of the present study was to evaluate the effects of weight loss on echocardiographic parameters 1 year after sleeve gastrectomy. Methods: This quasi-experimental study, conducted in Modarres Hospital, Tehran, Iran, from September 2016 to September 2017, recruited 101 patients. Those with morbid obesity (body mass index ≥40 kg/m2) had undergone surgery 1 year before the study commencement. All the patients underwent sleeve gastrectomy. The data of echocardiographic indices before and 1 year after surgery were recorded and analyzed. Results: The mean age of the participants was 37.11±9.81 ...
The journal of Tehran Heart Center, 2017
Cardiac lipomas are extremely rare tumors of the heart. They are usually symptomatic and rarely m... more Cardiac lipomas are extremely rare tumors of the heart. They are usually symptomatic and rarely may be found incidentally in autopsies. Here we describe a 23-year-old healthy man, in whose physical examination for employment a murmur was found incidentally. Transthoracic and then transesophageal echocardiographic examination showed a 4-cm oval-shaped mass in the right ventricular outflow tract. He underwent elective surgery, during which the tumor was removed under cardiopulmonary bypass and aortic-cross clamping via right atriotomy. The postoperative course was uneventful, and the patient was in good condition at 1 year's follow-up.
Clinical Medicine Insights: Cardiology, 2010
Echocardiography, 2013
BackgroundΤhe influence of atrial septal occluders in left atrial (LA) function after percutaneou... more BackgroundΤhe influence of atrial septal occluders in left atrial (LA) function after percutaneous closure of patent foramen ovale (PFO) has not been thoroughly studied.MethodsTwenty‐five patients (mean age 40.7 ± 12 years) undergoing percutaneous PFO closure were enrolled in this study. Transthoracic echocardiogram (TTE) was performed 3 and 6 months before the procedure. Volumetric indices (active emptying fraction: LA AEF, expansion index: LA EI, and passive emptying fraction: LA PEF), strain and strain rate (SR), were calculated during the contractile, reservoir, and conduit LA phases for the lateral, anterior, and inferior LA walls with TTE.ResultsAfter 3 months, a decrease in the SR of the LA anterior wall was observed (from 2.12 ± 0.22 to 1.66 ± 0.26, P < 0.045), while the LA lateral wall strain was found to be increased (from 0.708 ± 0.15 to 0.783 ± 0.159, P < 0.001). Moreover, simultaneously LA AEF was greater compared with baseline (from 31.0 ± 1.6 to 34.0 ± 1.6, P &l...
Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, 2020
Sarcoidosis is an inflammatory multisystem disease characterized by nonfatty granuloma accumulati... more Sarcoidosis is an inflammatory multisystem disease characterized by nonfatty granuloma accumulation in any organ. 1,2 The most common manifestation of sarcoidosis is pulmonary involvement in 80% of the cases, 3 but it can also present with involving other organs such as skin, parotid glands, spleen, liver, central nervous system involvement, bone, eye, lymph nodes, and even heart. 4 Heart disease has been reported in 50% of patients with sarcoidosis. 5 The clinical symptoms of cardiac sarcoidosis depend on the location and
Clinical Case Reports, Mar 10, 2020
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial ... more This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
World Journal of Cardiovascular Diseases, 2014
Introduction: Coronary artery disease (CAD) is the most common cause for left ventricular dysfunc... more Introduction: Coronary artery disease (CAD) is the most common cause for left ventricular dysfunction. Unfortunately, the treatment strategies of regional myocardial diastolic dysfunction in patients with CAD have not been well characterized and benefit of percutaneous coronary intervention (PCI) as a treatment strategy is not clear. So the present study aimed to assess the effects of PCI on regional and global left ventricular diastolic dysfunction in patients with CAD assessed by strain rate (SR) imaging. Methods: Thirty adult symptomatic patients with coronary artery disease that underwent coronary angiography and candidate for PCI on left anterior descending artery were enrolled to our study. Echocardiographic findings and early diastolic SR were measured before and 48 hours after PCI. Results: Mean age of the patients was 59.9 ± 8.3 years. Most of the left ventricular diastolic parameters showed significant difference before and after elective PCI; while mitral E velocity, DT, E/A and pulmonary vein flow before and after PCI did not show significant difference assessed by statically test. Also before PCI, mean (SD) of peak early diastolic SR in ischemic regions (1.89 ± 0.22) was smaller than of non-ischemic regions (2.53 ± 0.26) while after PCI this parameter became similar in ischemic regions (2.55 ± 0.27) and non-ischemic regions (2.55 ± 0.26). Conclusion: Most of the left ventricular diastolic parameters improved after PCI in CAD patients. Also regional myocardial relaxation as measured by peak early diastolic SR (ESR) in the ischemic segments improved significantly compared with that in non-ischemic segments.
Research Square (Research Square), May 9, 2022
There are scarce investigations regarding the effect of obesity on left ventricular systolic func... more There are scarce investigations regarding the effect of obesity on left ventricular systolic function in absence of other risk factors. This study aimed to identify the global longitudinal strain (GLS) changes in isolated overweight and obese people in absence of other risk factors. Method A total of 60 obese people, 30 overweight, and 30 healthy controls were included in the study. Echocardiographic ndings including apical 2-, 3-and 4-chamber GLS, GLS total, left ventricular (LV) diameter, interventricular septum thickness, and PAP were measured and compared between the three groups. Results Analyses showed that LV diameter in healthy controls was signi cantly lower compared to overweight (P = 0.02) and obese (P < 0.0001) participants. Also, the interventricular septal thickness was signi cantly increased in overweight (P = 0.007) and obese (P < 0.0001) individuals compared to participants with normal BMI. The mean and standard deviation (Mean ± SD) of total GLS values were − 22.29% ± 1.89% for normal weight,-22.09% ± 1.91% for overweight, and − 19.88% ± 2.34% for obese individuals. The total GLS of obese participants was signi cantly lower than overweight and normal controls (P < 0.0001). It was observed that the GLS values were signi cantly lower in people with BMI higher than 40. The mean ± SD of total GLS values were − 20.68% (1.84%) for BMI ≤ 40 patients, and − 18.51% (2.52%) for BMI > 40 patients. Conclusion All GLS values had a moderately strong correlation with BMI values. Subclinical LV dysfunction was detected in overweight people in addition to obese subjects.
DOAJ (DOAJ: Directory of Open Access Journals), Apr 1, 2021
Introduction: Epicardial adipose tissue (EAT), as a visceral adipose tissue, is associated with v... more Introduction: Epicardial adipose tissue (EAT), as a visceral adipose tissue, is associated with various cardiometabolic risk factors, such as fasting plasma glucose, systemic blood pressure and serum low-density lipoprotein. Using EAT thickness as a cost-efficient assessment tool for stratifying the risk of coronary artery disease (CAD) is still controversial. Methods: We enrolled 250 consecutive patients who underwent coronary angiography during 2016 and gathered their demographic. Echocardiographic examinations were performed in the left lateral decubitus position and EAT thickness was measured in standard parasternal long-axis (PLAX) and apical four chamber views. Results: 250 patients including 156 men (mean age: 57.66) and 94 women (mean age: 61.19) were enrolled. Two vessel disease (2VD) and three vessel disease (3VD) were significantly associated with hyperlipidemia (P: 0.04), CKD (Chronic Kidney Disease) (P: 0.001), diabetes mellitus (P: 0.001) and smoking habits (P: 0.001). Also, EAT thickness in PLAX view (P<0.001), and not four chamber view (P: 0.136), was significantly associated and correlated with increased involvement of coronary arteries in catheterization. Conclusion: Although EAT thickness in PLAX view was significantly correlated with 2VD and 3VD, this correlation was not strong and the accuracy of this approach needs further evaluation.
Authorea (Authorea), Jul 4, 2020
Background: There are some suggestions that global myocardial strain (GLS) early after ST-elevati... more Background: There are some suggestions that global myocardial strain (GLS) early after ST-elevation myocardial infarction (STEMI) is a predictor of improvement in left ventricular ejection fraction (LVEF). The goal of this study was to evaluate LV recovery after STEMI intervention based on GLS values. Methods: The study population consists of 43 patients with acute STEMI and no history of prior coronary intervention treated with primary percutaneous coronary intervention. LVEF and myocardial strain indices were measured 48 hours and two months after STEMI by transthoracic echocardiography and speckle tracking method. More than 5% improvement in LVEF was considered significant. Results: GLS values were significantly higher in patients with >5% improvement in LVEF 2 months after the STEMI (GLS=15.76% in patients with >5% improvement vs. 11.54% in the other group, P<0.05). ROC analysis suggested GLS values more than 13.5 to be a predictor of significant LVEF improvement 2 months after STEMI. Higher GLS was observed in patients with inferior, posterior and inferoseptal STEMI versus anterior, extensive or anteroseptal STEMI and in patients with right coronary occlusion versus occlusion of the left anterior descending or circumflex arteries. Conclusion: We have observed that early longitudinal LV strain after STEMI is a predictor of recovery after STEMI. This is a useful method to predict early LV recovery after STEMI. GLS values of more than 13.5% are a significant predictor of significant LVEF improvement.
The Journal of Tehran University Heart Center, Sep 7, 2019
Clinical Case Reports, 2022
Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch ar... more Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch arteries. Here, we describe an atypical presentation of the disease with heart failure.
Iranian Heart Journal, Apr 1, 2021
Clinical Case Reports, 2022
Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch ar... more Takayasu arteritis (TA) is an inflammatory disease that affects the aorta and the major branch arteries. Here, we describe an atypical presentation of the disease with heart failure.
Emergency, 2018
Patent foramen ovale (PFO) is usually asymptomatic; however, it could be quite dangerous for pati... more Patent foramen ovale (PFO) is usually asymptomatic; however, it could be quite dangerous for patients with right side clot in which thrombus can transmit the PFO and paradoxically emboli to systemic circulation. Here we present a patient with ankle fracture and paradoxical embolus to the brain, who was successfully treated with emergent thrombectomy, inferior vena cava (IVC) filter placement and anticoagulation therapy. Despite the high rate of mortality in these patients, fortunately our patient survived with surgical treatment.
International Journal of Computer Assisted Radiology and Surgery, 2021
Cardiac multimodal image fusion can offer an image with various types of information in a single ... more Cardiac multimodal image fusion can offer an image with various types of information in a single image. Many coronary stenosis, which are anatomically clear, are not functionally significant. The treatment of such kind of stenosis can cause irreversible effects on the patient. Thus, choosing the best treatment planning depend on anatomical and functional information is very beneficial. An algorithm for the fusion of coronary computed tomography angiography (CCTA) as an anatomical and transthoracic echocardiography (TTE) as a functional modality is presented. CCTA and TTE are temporally registered using manifold learning. A pattern search optimization algorithm, using normalized mutual information, is used to find the best match slice to TTE frame from CCTA volume. By employing a free-form deformation, the heart's non-rigid deformations are modeled. The spatiotemporal registered TTE frame is embedded to achieve the fusion result. The accuracy is evaluated on CCTA and TTE data obt...
Introduction: Coronary Artery Disease (CAD) is the most common cause for left ventricular dysfunc... more Introduction: Coronary Artery Disease (CAD) is the most common cause for left ventricular dysfunction. Unfortunately, the treatment strategies of regional myocardial diastolic dysfunction in patients with CAD have not been well characterized and benefit of Percutaneous Coronary Intervention (PCI) as a treatment strategy is not clear. So the present study aimed to assess the effects of PCI on isolated left ventricular diastolic dysfunction in patients with CAD by using Strain Rate (SR) imaging. Methods: Thirty adult patients with coronary artery disease candidate for PCI on left anterior descending artery were enrolled to our study. Echocardiographic finding and early diastolic SR was measured before and 48 hours after PCI. Results: Mean age of the patients was 59.9±8.3 years. All of the left ventricular diastolic parameters showed significant difference before and after elective PCI; while pulmonary vein flow before and after PCI did not show any significant differences by using McN...
Frontiers in Biomedical Technologies, 2021
Purpose: Multimodal Cardiac Image (MCI) registration is one of the evolving fields in the diagnos... more Purpose: Multimodal Cardiac Image (MCI) registration is one of the evolving fields in the diagnostic methods of Cardiovascular Diseases (CVDs). Since the heart has nonlinear and dynamic behavior, Temporal Registration (TR) is the fundamental step for the spatial registration and fusion of MCIs to integrate the heart's anatomical and functional information into a single and more informative display. Therefore, in this study, a TR framework is proposed to align MCIs in the same cardiac phase. Materials and Methods: A manifold learning-based method is proposed for the TR of MCIs. The Euclidean distance among consecutive samples lying on the Locally Linear Embedding (LLE) of MCIs is computed. By considering cardiac volume pattern concepts from distance plots of LLEs, six cardiac phases (end-diastole, rapid-ejection, end-systole, rapid-filling, reduced-filling, and atrial-contraction) are temporally registered. Results: The validation of the proposed method proceeds by collecting the...
The Journal of Tehran University Heart Center, 2021
Tricuspid valve myxomas are very uncommon tumors that could be found after the occurrence of pu... more Tricuspid valve myxomas are very uncommon tumors that could be found after the occurrence of pulmonary thromboembolism, symptomatic tricuspid obstruction, and right-sided heart failure. Herein, we describe a 42-year-old woman evaluated for an abdominal mass. In preoperative consultation, a tricuspid valve mass was detected in echocardiography. She underwent the removal of a benign uterine myoma and a myxoma of the tricuspid valve. Tricuspid valve myxomas constitute a scarce diagnosis. They could be asymptomatic, occurring in unusual locations and in association with benign tumors in other organs. Our patient was asymptomatic, underscoring the significance of the early diagnosis of this type of tumor to prevent further catastrophic events.
The Journal of Tehran University Heart Center, 2019
Background: Bariatric surgery is efficiently associated with the long-term resolution of obesity ... more Background: Bariatric surgery is efficiently associated with the long-term resolution of obesity and its related morbidities. Not only can this surgical modality improve the metabolic profile, diastolic and systolic cardiac functions, and the clinical symptoms of heart failure or cardiomyopathy, but it can also reduce the atherosclerosis risk, ventricular mass, and pericardial fat thickness. The aim of the present study was to evaluate the effects of weight loss on echocardiographic parameters 1 year after sleeve gastrectomy. Methods: This quasi-experimental study, conducted in Modarres Hospital, Tehran, Iran, from September 2016 to September 2017, recruited 101 patients. Those with morbid obesity (body mass index ≥40 kg/m2) had undergone surgery 1 year before the study commencement. All the patients underwent sleeve gastrectomy. The data of echocardiographic indices before and 1 year after surgery were recorded and analyzed. Results: The mean age of the participants was 37.11±9.81 ...
The journal of Tehran Heart Center, 2017
Cardiac lipomas are extremely rare tumors of the heart. They are usually symptomatic and rarely m... more Cardiac lipomas are extremely rare tumors of the heart. They are usually symptomatic and rarely may be found incidentally in autopsies. Here we describe a 23-year-old healthy man, in whose physical examination for employment a murmur was found incidentally. Transthoracic and then transesophageal echocardiographic examination showed a 4-cm oval-shaped mass in the right ventricular outflow tract. He underwent elective surgery, during which the tumor was removed under cardiopulmonary bypass and aortic-cross clamping via right atriotomy. The postoperative course was uneventful, and the patient was in good condition at 1 year's follow-up.
Clinical Medicine Insights: Cardiology, 2010
Echocardiography, 2013
BackgroundΤhe influence of atrial septal occluders in left atrial (LA) function after percutaneou... more BackgroundΤhe influence of atrial septal occluders in left atrial (LA) function after percutaneous closure of patent foramen ovale (PFO) has not been thoroughly studied.MethodsTwenty‐five patients (mean age 40.7 ± 12 years) undergoing percutaneous PFO closure were enrolled in this study. Transthoracic echocardiogram (TTE) was performed 3 and 6 months before the procedure. Volumetric indices (active emptying fraction: LA AEF, expansion index: LA EI, and passive emptying fraction: LA PEF), strain and strain rate (SR), were calculated during the contractile, reservoir, and conduit LA phases for the lateral, anterior, and inferior LA walls with TTE.ResultsAfter 3 months, a decrease in the SR of the LA anterior wall was observed (from 2.12 ± 0.22 to 1.66 ± 0.26, P < 0.045), while the LA lateral wall strain was found to be increased (from 0.708 ± 0.15 to 0.783 ± 0.159, P < 0.001). Moreover, simultaneously LA AEF was greater compared with baseline (from 31.0 ± 1.6 to 34.0 ± 1.6, P &l...
Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, 2020
Sarcoidosis is an inflammatory multisystem disease characterized by nonfatty granuloma accumulati... more Sarcoidosis is an inflammatory multisystem disease characterized by nonfatty granuloma accumulation in any organ. 1,2 The most common manifestation of sarcoidosis is pulmonary involvement in 80% of the cases, 3 but it can also present with involving other organs such as skin, parotid glands, spleen, liver, central nervous system involvement, bone, eye, lymph nodes, and even heart. 4 Heart disease has been reported in 50% of patients with sarcoidosis. 5 The clinical symptoms of cardiac sarcoidosis depend on the location and
Clinical Case Reports, Mar 10, 2020
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial ... more This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
World Journal of Cardiovascular Diseases, 2014
Introduction: Coronary artery disease (CAD) is the most common cause for left ventricular dysfunc... more Introduction: Coronary artery disease (CAD) is the most common cause for left ventricular dysfunction. Unfortunately, the treatment strategies of regional myocardial diastolic dysfunction in patients with CAD have not been well characterized and benefit of percutaneous coronary intervention (PCI) as a treatment strategy is not clear. So the present study aimed to assess the effects of PCI on regional and global left ventricular diastolic dysfunction in patients with CAD assessed by strain rate (SR) imaging. Methods: Thirty adult symptomatic patients with coronary artery disease that underwent coronary angiography and candidate for PCI on left anterior descending artery were enrolled to our study. Echocardiographic findings and early diastolic SR were measured before and 48 hours after PCI. Results: Mean age of the patients was 59.9 ± 8.3 years. Most of the left ventricular diastolic parameters showed significant difference before and after elective PCI; while mitral E velocity, DT, E/A and pulmonary vein flow before and after PCI did not show significant difference assessed by statically test. Also before PCI, mean (SD) of peak early diastolic SR in ischemic regions (1.89 ± 0.22) was smaller than of non-ischemic regions (2.53 ± 0.26) while after PCI this parameter became similar in ischemic regions (2.55 ± 0.27) and non-ischemic regions (2.55 ± 0.26). Conclusion: Most of the left ventricular diastolic parameters improved after PCI in CAD patients. Also regional myocardial relaxation as measured by peak early diastolic SR (ESR) in the ischemic segments improved significantly compared with that in non-ischemic segments.
Research Square (Research Square), May 9, 2022
There are scarce investigations regarding the effect of obesity on left ventricular systolic func... more There are scarce investigations regarding the effect of obesity on left ventricular systolic function in absence of other risk factors. This study aimed to identify the global longitudinal strain (GLS) changes in isolated overweight and obese people in absence of other risk factors. Method A total of 60 obese people, 30 overweight, and 30 healthy controls were included in the study. Echocardiographic ndings including apical 2-, 3-and 4-chamber GLS, GLS total, left ventricular (LV) diameter, interventricular septum thickness, and PAP were measured and compared between the three groups. Results Analyses showed that LV diameter in healthy controls was signi cantly lower compared to overweight (P = 0.02) and obese (P < 0.0001) participants. Also, the interventricular septal thickness was signi cantly increased in overweight (P = 0.007) and obese (P < 0.0001) individuals compared to participants with normal BMI. The mean and standard deviation (Mean ± SD) of total GLS values were − 22.29% ± 1.89% for normal weight,-22.09% ± 1.91% for overweight, and − 19.88% ± 2.34% for obese individuals. The total GLS of obese participants was signi cantly lower than overweight and normal controls (P < 0.0001). It was observed that the GLS values were signi cantly lower in people with BMI higher than 40. The mean ± SD of total GLS values were − 20.68% (1.84%) for BMI ≤ 40 patients, and − 18.51% (2.52%) for BMI > 40 patients. Conclusion All GLS values had a moderately strong correlation with BMI values. Subclinical LV dysfunction was detected in overweight people in addition to obese subjects.
DOAJ (DOAJ: Directory of Open Access Journals), Apr 1, 2021
Introduction: Epicardial adipose tissue (EAT), as a visceral adipose tissue, is associated with v... more Introduction: Epicardial adipose tissue (EAT), as a visceral adipose tissue, is associated with various cardiometabolic risk factors, such as fasting plasma glucose, systemic blood pressure and serum low-density lipoprotein. Using EAT thickness as a cost-efficient assessment tool for stratifying the risk of coronary artery disease (CAD) is still controversial. Methods: We enrolled 250 consecutive patients who underwent coronary angiography during 2016 and gathered their demographic. Echocardiographic examinations were performed in the left lateral decubitus position and EAT thickness was measured in standard parasternal long-axis (PLAX) and apical four chamber views. Results: 250 patients including 156 men (mean age: 57.66) and 94 women (mean age: 61.19) were enrolled. Two vessel disease (2VD) and three vessel disease (3VD) were significantly associated with hyperlipidemia (P: 0.04), CKD (Chronic Kidney Disease) (P: 0.001), diabetes mellitus (P: 0.001) and smoking habits (P: 0.001). Also, EAT thickness in PLAX view (P<0.001), and not four chamber view (P: 0.136), was significantly associated and correlated with increased involvement of coronary arteries in catheterization. Conclusion: Although EAT thickness in PLAX view was significantly correlated with 2VD and 3VD, this correlation was not strong and the accuracy of this approach needs further evaluation.
Authorea (Authorea), Jul 4, 2020
Background: There are some suggestions that global myocardial strain (GLS) early after ST-elevati... more Background: There are some suggestions that global myocardial strain (GLS) early after ST-elevation myocardial infarction (STEMI) is a predictor of improvement in left ventricular ejection fraction (LVEF). The goal of this study was to evaluate LV recovery after STEMI intervention based on GLS values. Methods: The study population consists of 43 patients with acute STEMI and no history of prior coronary intervention treated with primary percutaneous coronary intervention. LVEF and myocardial strain indices were measured 48 hours and two months after STEMI by transthoracic echocardiography and speckle tracking method. More than 5% improvement in LVEF was considered significant. Results: GLS values were significantly higher in patients with >5% improvement in LVEF 2 months after the STEMI (GLS=15.76% in patients with >5% improvement vs. 11.54% in the other group, P<0.05). ROC analysis suggested GLS values more than 13.5 to be a predictor of significant LVEF improvement 2 months after STEMI. Higher GLS was observed in patients with inferior, posterior and inferoseptal STEMI versus anterior, extensive or anteroseptal STEMI and in patients with right coronary occlusion versus occlusion of the left anterior descending or circumflex arteries. Conclusion: We have observed that early longitudinal LV strain after STEMI is a predictor of recovery after STEMI. This is a useful method to predict early LV recovery after STEMI. GLS values of more than 13.5% are a significant predictor of significant LVEF improvement.