Fariba Iraji - Profile on Academia.edu (original) (raw)

Papers by Fariba Iraji

Evaluating the efficacy of microneedling technique in treating striae alba lesions

Archives of Dermatological Research

Topical Nicotinamide in Combination with Calcipotriol for the Treatment of Mild to Moderate Psoriasis: A Double-Blinded, Randomized, Comparative Study

مجله دانشکده پزشکی اصفهان, 2015

Background: Current treatment strategies of psoriasis are not completely satisfactorily. By inhib... more Background: Current treatment strategies of psoriasis are not completely satisfactorily. By inhibiting inflammatory cytokines, nicotinamide may enhance the effects of current topical treatments. We investigated whether the combination of topical calcipotriol and nicotinamide is more effective than calcipotriol alone in treatment of psoriasis. Methods: Adult patients with mild to moderate psoriasis were randomized to receive topical calcipotriol 0.005% and nicotinamide 4% in combination or calcipotriol 0.005% alone, twice daily for 12 weeks. Patients were visited by a dermatologist at baseline and then, after the first and third months of therapy; and psoriasis severity was evaluated using the modified psoriasis area and severity index (PASI). Also, patient's satisfaction was evaluated at the end of the trial using a 10-point rating scale. Findings: Sixty five patients (35 men) with the mean age of 36.5 ± 8.5 years completed the trial. Lesions on both sides were similar regarding...

مقایسه‌ی اثربخشی استفاده‌ی توأم از تاکرولیموس و مینوکسیدیل با مینوکسیدیل به تنهایی در درمان بیماران مبتلا به Alopecia areata

مجله دانشکده پزشکی اصفهان, 2014

مقدمه : Alopecia areata یک بیماری ایدیوپاتیک است که در آن ریزش موی ناحیه‌ای وجود دارد. روش‌های در... more مقدمه : Alopecia areata یک بیماری ایدیوپاتیک است که در آن ریزش موی ناحیه‌ای وجود دارد. روش‌های درمانی زیادی برای ریزش موی سکه‌ای (ریزش موی کمتر از 50 درصد) پیشنهاد شده است که تزریق کورتیکواسترویید، مینوکسیدیل موضعی 5% و پماد یا کرم آنترالین در قسمت‌های بدون موی پوست از آن جمله است. از آن جایی که در مطالعات اخیر نقش خودایمنی و اتوآنتی‌بادی‌ها را در بیماری Alopecia areata مطرح شده و از داروهای تنظیم کننده‌ی سیستم ایمنی در درمان آن بهره گرفته شده است، این مطالعه به منظور مقایسه‌ی اثربخشی استفاده‌ی توأم از تاکرولیموس و مینوکسیدیل با مینوکسیدیل به تنهایی در درمان Alopecia areata به انجام رسید. روش‌ها: این مطالعه از نوع کارآزمایی بالینی تصادفی و دوسو کور بود که در بیمارستان الزهرا (س) و مرکز پوست و سالک صدیقه‌ی طاهره (س) وابسته به دانشگاه علوم پزشکی اصفهان از مهر ماه 1391 لغایت 1392 به انجام رسید. در این مطالعه، 96 ضایعه در 54 بیمار مبتلا به Alopecia areata با مساحت و تعداد ضایعات متفاوت در دو گروه درمانی مورد مطالعه و بررسی قرار گرفتند. یک گروه با محلول مینوکسیدیل 5 درصد و کرم تاکرولیموس...

Skin Reactions with Losartan and Enalapril in Cardiac Patients

مجله دانشکده پزشکی اصفهان, 2012

Background: Numerous reports have been published about the skin reaction after using angiotensin ... more Background: Numerous reports have been published about the skin reaction after using angiotensin II converting enzyme inhibitors (ACEIs) such as enalapril and angiotensin II receptor blockers (ARBs) such as losartan. However, no such investigations have been conducted to evaluate skin complications after ACEIs and ARBs intake. According to racial differences in reaction to medications and high rate prescription of theses mentioned drugs, we aimed to design the present study. Methods: This cross-sectional study was performed on hospitalized or referred patients who were taking losartan or enalapril in University Hospitals of the Isfahan University of Medical Sciences in 2008. 200 patients were randomly enrolled to the study. Findings: Skin reactions developed in 4.5% of the participants (4.5% in losartan and 5% in enalapril users). The most common skin complications were urticaria, maculopapular rashes and angioedema. The average time from taking the medication to the development of ...

SUMMARY According to the hypothesis on the stimulating effect of adenosine on increasing fibrobla... more SUMMARY According to the hypothesis on the stimulating effect of adenosine on increasing fibroblast growth factor 7 in dermal papilla cells and its vasorelaxant effect, we performed this study to compare the effect of topical minoxidil 5 % and adenosine 0.75 % on male pattern androgenetic alopecia. This prospective-randomized study recruited 110 male patients suffering from grade II-V Hamilton androgenetic alo-pecia. Fifty-five patients received minoxidil 5 % (group 1) and adenos-ine 0.75 % (group 2) each. Later, 16 patients were excluded due to al-lergic reactions or loss to follow up. After 3 and 6 months of treatment, complete and relative recovery rates alongside patient satisfaction rate (faster prevention of primary hair loss and appearance of newly grown hair) were compared between the groups. After 3 months of treat-ment, relative recovery was achieved in 2.4 % and 1.9 % of patients in group 1 and group 2, respectively, which was not significantly different (p=0.17). During ...

Medical journal of Tabriz University of Medical Sciences and Health Services, 2021

Background: Patients admitted in especial units such as coronary care unit (CCU) require intensiv... more Background: Patients admitted in especial units such as coronary care unit (CCU) require intensive care for different aspects including skin problems. Here in this report we aimed to perform a survey on different skin lesions in patients admitted in CCU by the time of admission and when discharging. Methods: In this cross-sectional study, we had a survey on 200 patients admitted in CCU in AL-Zahra hospital, Isfahan. A dermatologist observed and examined each patients for any skin lesions by the time of admission and when discharging from CCU. Results: Here we showed that 15 percent of patients admitted in CCU have at least one skin lesion and also we indicated that seborrhea dermatitis and then rosacea have the most prevalence by the time of admission in CCU. Other skin lesions were acute skin failure. We also showed that prevalence of bed sore and pressure sores increased amazingly during admission. Conclusion: Rosacea, seborrhea dermatitis and drug allergic reactions after pressur...

بررسی رابطه سطح آنزیم گلوکز شش فسفات دهیدروژناز به روش اسپکتروفوتومتری با بیماری ویتیلیگو

Introduction: Vitiligo is a relatively common and acquired disease with an uncertain cause. There... more Introduction: Vitiligo is a relatively common and acquired disease with an uncertain cause. Therefore, it is essential to identify effective factors and prevent them. The aim of this study was to determine the relationship between the levels of glucose 6-phosphate dehydrogenase (G6PD) and vitiligo disease by spectrophotometry. Methods: This study was performed on 104 individuals (51 patients with vitiligo and 53 controls). After obtaining patients' satisfaction and recording the patients' demographic data, serum G6PD levels were measured and recorded. Chi-square and ANOVA tests were used to compare the data. Results: The study showed that G6PD levels were significantly lower in patients with vitiligo than in healthy subjects (292.37 vs. 298.58 U/g Hb) (P<0.001), and by grouping patients in the terms of vitiligo type, the G6PD levels had a reverse and significant relation with vitiligo severity (among patients with limited vitiligo (r=-0.499, P=0.006) and with generalized ...

International Journal of Dermatology, 2020

Background: Keratosis rubra pilaris is a common condition with an estimated percentage of 40% inv... more Background: Keratosis rubra pilaris is a common condition with an estimated percentage of 40% involvement in the population. This condition is inherited as an autosomal dominant trait and more commonly involves patients with dry skin. In the current study, we evaluated the efficacy of intense pulsed light (IPL) plus ammonium lactate versus ammonium lactate alone in the treatment of keratosis pilaris.Methods: A total of 50 patches were selected in 10 patients. If there were two similar patches with the same color and same location, each of them was randomized to receive ammonium lactate (Kerapil cream®) or ammonium lactate (Kerapil cream®) +IPL. Treatment was performed for 3 months, and improvement was rated by physicians and patients one month and two months after the intervention.Results: The grade of improvement in the IPL + ammonium lactate was not significantly higher than ammonium lactate alone group as rated by blinded physicians at week 4 (P > 0.05). However, the score of ...

Dermatology case diagnosis

JRMS, 2007

Q‐switched frequency‐doubled Nd: YAG (532 nm) laser versus trichloroacetic acid 35% peeling in the treatment of dorsal hand solar lentigo: An assessor‐blind split‐hand randomized controlled trial

Journal of Cosmetic Dermatology

acne vulgaris: A randomized, double-blind placebo-controlled acne vulgaris: A randomized, double-blind placebo-controlled acne vulgaris: A randomized, double-blind placebo-controlled acne vulgaris: A randomized, double-blind placebo-controlled acne vulgaris: A randomized, double-blind placebo-contro

Background: Finding an effective treatment for acne that is well tolerated by the patients is a c... more Background: Finding an effective treatment for acne that is well tolerated by the patients is a challenge. One study has suggested the efficacy of tea tree oil in treatment of the acne vulgaris. Aim: To determine the efficacy of tea tree oil in mild to moderate acne vulgaris. Methods: This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris. They were randomly divided into two groups and were treated with tea tree oil gel (n=30) or placebo (n=30). They were followed every 15 days for a period of 45 days. Response to treatment was evaluated by the total acne lesions counting (TLC) and acne severity index (ASI). The data was analyzed statistically using t-test and by SPSS program. Results: There were no significant differences regarding demographic characteristics between the two groups. There was a significant difference between tea tree oil gel and placebo in the improvement of the TLC and also regarding improvement of the ASI. I...

Clinical Case Reports, 2019

This is an open access article under the terms of the Creative Commons Attribution License, which... more This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

The Internet Journal of Dermatology, 2007

Non melanoma skin cancers (NMSC) are one of the most prevalent malignancies of humans. Although t... more Non melanoma skin cancers (NMSC) are one of the most prevalent malignancies of humans. Although the mortality rate is not high for these cancers, they may cause high morbidity for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers. Aims: To determine the incidence of Non-Melanoma skin cancers in Esfahan: Settings and Design: This was a retrospective study. We used data of the cancer registry center for performing this study. Methods and Material: Statistical analysis used: Descriptional statistical tests and t-student test were used for statistical analysis. Results: Overall 1681 cases were registered that included 352 cases of SCC and 1329 cases with BCC. The incidence of NMSC was calculated to be 10.67/10`000 population Conclusions: Regarding topographic results, the most prevalent site for BCC were middle face and then head and neck and the least prevalent site was lower extremity. The most prevalent site for SCC was middle face and the least prevalent site was the trunk.

Purpura and Microvascular Occlusion

Rook's Textbook of Dermatology

... Introduction Purpura and bruising, the main terms used to describe bleeding into the skin, ma... more ... Introduction Purpura and bruising, the main terms used to describe bleeding into the skin, may occur as isolated phenomena or as part of a systemic disorder. ... Despite these limitations, as a practical matter the initial approach to a patient with purpura must typically start with a ...

Dermatology Research and Practice, 2021

Objective Vitiligo is a common, autoimmune disease that results in the destruction of the melanoc... more Objective Vitiligo is a common, autoimmune disease that results in the destruction of the melanocytes and manifests as depigmented macules on various areas of the skin. Numerous treatment options have been proposed for vitiligo. The purpose of this study was to compare the efficacy of microneedling plus topical pimecrolimus 1% versus the sole use of topical pimecrolimus 1% for the treatment of vitiligo. Methods This clinical trial was conducted on 30 skin lesions on 15 Al-Zahra hospital patients. Each patient had two similar lesions in the limb area, and each lesion was considered a separate treatment group. The left or right side of the patient's lesion was randomly assigned to receive microneedling plus topical pimecrolimus for three months, while the other side received only topical pimecrolimus 1%. As part of the follow-up, digital photography was taken at the baseline and biweekly for three months after treatment and six months' follow-up. The following methods were use...

A Rare Case of Branchio-oculo-facial Syndrome: Clinical and Histopathological Features

Advanced Biomedical Research, 2018

Branchio-oculo-facial syndrome (BOFS), a rare, multiple-malformation congenital disorder, is char... more Branchio-oculo-facial syndrome (BOFS), a rare, multiple-malformation congenital disorder, is characterized by facial anomalies, including associated cutaneous and ocular abnormalities. We report a new case of BOFS in an 11-year-old male child with bilateral cervical erythematous scaly linear plaque associated with scar formation and erosion. Although BOFS is very rare, physicians, especially dermatologists, should be aware of the cutaneous and histopathological features of BOFS due to impacts of the associated anomalies.

Phenotypical identification of agent of lupin's bacterial wet rot

Analysis of Personal and Social Environmental Factors affecting the Effectiveness of Participation in Sports for All: Comparison of Incomplete Participants and Full Participants

Journal of Sport and Leisure Studies, 2021

Vaccination in Leishmaniasis: A Review Article

Iranian Biomedical Journal, 2022

Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through female san... more Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics and has been reported in more than 98 countries. Due to the side effects of anti-Leishmania drugs and the emergence of drug-resistant isolates, there is currently no encouraging prospect of introducing an effective therapy for the disease. Hence, it seems that the key to disease control management is the introduction of an effective vaccine, particularly against its cutaneous form. Advances in understanding underlying immune mechanisms are feasibale using a variety of candidate antigens, including attenuated live parasites, crude antigens, pure or recombinant Leishmania proteins, Leishmania genes encoding protective proteins, as well as immune system activators from the saliva of parasite vectors. However, there is still no vaccine against different types of human leishmaniasis. In this study, we review the ...

Fractional Erbium:YAG Laser (2940 nm) plus Topical Hydroquinone Compared to Intradermal Tranexamic Acid plus Topical Hydroquinone for the Treatment of Refractory Melasma: A Randomized Controlled Trial

Journal of Dermatological Treatment, 2021

OBJECTIVES Melasma is a chronic acquired condition characterized by grayish-brown macules and pat... more OBJECTIVES Melasma is a chronic acquired condition characterized by grayish-brown macules and patches with a distinct border on the face. Although various treatments methods have been suggested for treating melasma, none has been completely successful. The aim of the study was to compare the efficiency of erbium: yttrium-aluminum-garnet (Er:YAG) laser and 4% hydroquinone (HQ) with the effects of intradermal tranexamic acid (TA) and 4% HQ for the treatment of refractory melasma. METHODS The study included 31 female patients with refractory melasma. The left or right side of the patient's face was chosen randomly to receive laser therapy with topical HQ on the one side (i.e., the laser side) and intradermal injection of TA plus topical HQ on the other side (i.e., the mesotherapy side). Digital photography was performed at baseline, at the end of the treatment, and three months after the treatment as follow-up. Two independent dermatologists evaluated the modified Melasma Area and Severity Index (mMASI) score according to the pictures. Overall, 27 patients completed the study and went through the clinical evaluation. RESULTS Treatment using HQ in combination with either Er:YAG laser therapy or intradermal injection of TA significantly improved the hemi-mMASI and resulted in higher patient satisfaction. While the improvement was not significantly different between the two regiments after the treatment and upon follow up and both were equally efficient in the treatment of refractory melasma (p = 1.308), recurrence rate was higher after treatment with Er:YAG laser than TA (12% vs 34%). CONCLUSION This study confirmed the comparable efficacy of TA plus topical HQ versus Er:YAG laser plus topical HQ for the treatment of refractory melasma. Both groups improved significantly and no subject left the treatment because of adverse effects.