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Journal of the American Geriatrics Society, 2011
The review found that evidence for the effectiveness of antidepressants in people with dementia a... more The review found that evidence for the effectiveness of antidepressants in people with dementia and depression was inconclusive and that larger studies were required. The review was generally well conducted and these findings appear reliable. Authors' objectives To evaluate the efficacy of antidepressants for people with depression and dementia. Searching MEDLINE (from 1966) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched to May 2010. Search terms were reported. The reference lists of articles retrieved were checked for further studies. Study selection Eligible were double-blinded placebo-controlled parallel-group randomised controlled trials (RCTs) of antidepressants marketed in the USA. Participants were required to have acute-phase depression and dementia diagnosed by established criteria. Required outcomes were response, remission, symptom change (using objective measures) and treatment discontinuation. Detailed definitions of outcomes were provided in the review. Bibliographic details Nelson JC, Devanand DP. A systematic review and meta-analysis of placebo-controlled antidepressant studies in people with depression and dementia.
Background. The Barkley Adult Attention Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV (BA... more Background. The Barkley Adult Attention Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV (BAARS-IV) was developed, and it demonstrated good psychometric properties. The BAARS-IV includes 27 questions on the symptoms of adult ADHD. The purpose of the present study is to investigate the psychometric testing of the Persian version of BAARS-IV among the elderlies in Tabriz City. Method. This cross-sectional study was conducted in Tabriz City-in the west of Iran-in 2015 via enrolling of 121 old-aged people. We did the process of translation and adaptation of BAARS-IV and examined its concurrent validity, internal consistency, and test-retest reliability. Result. The BAARS-IV demonstrated good internal consistency and test-retest reliability. Correlations between the BAARS-IV and the CAARS-S: SV were high and evidence supporting concurrent validity was revealed. Cronbach's alpha for the overall scale and subscales stood at 0.89, 0.81, 0.66, 0.56, and 0.82, respectively. Conclusion. The Persian BAARS-IV showed acceptable reliability and validity. BAARS-IV was determined to be composed of internally consistent and psychometrically sound items.
Transplantation Proceedings, 2007
Introduction. Hyperlipidemia is a multifactorial event that frequently develops following renal t... more Introduction. Hyperlipidemia is a multifactorial event that frequently develops following renal transplantation and may worsen the patient's prognosis. The aim of this study was to evaluate the incidence and concomitant factors for hyperlipidemia. Methods. We studied 687 renal transplant recipients from 1988 to 2004 using a cross-sectional design to determine the frequency of hypercholestrolemia and hypertriglyceridemia before and 1 month to 1 year after renal transplantation, to evaluate its relation to patient and graft prognosis in two medical centers in Iran. Cyclosporine was the constant part of immunosuppressive treatment in all study subjects. Results. One and 5-year graft survival times were 94.23% and 81.34%, respectively. The prevalence of hypercholestrolemia after transplantation was 59.9%. Mean (Ϯ 2 SE) serum cholesterol levels before and after transplantation were 161.15 Ϯ 3.81 and 213.83 Ϯ 4.53 mg/dL respectively (P ϭ .000). Triglycerides levels, were 159.99 Ϯ 13.08 and 196.28 Ϯ 19.6 mg/dL respectively. There was no significant correlation between cyclosporine dose, graft and patient survivals, and severity of hyperlipidemia (determined by cholesterol and triglyceride levels). Conclusions. Lipid metabolism abnormalities observed in this study were similar to other reports. There was no correlation with patient or graft survival. In addition, there may routes for development of hyperlipidemia other than adverse complications of immunosuppressive drugs.
... Masoud Ahmadzad Asl a, Ahmadreza Shamshiri b, Ahmad Hajebi *, Morteza Naserbakht c, Mohammadb... more ... Masoud Ahmadzad Asl a, Ahmadreza Shamshiri b, Ahmad Hajebi *, Morteza Naserbakht c, Mohammadbagher Saberi Zafarghandi d, Farnoush Davoudi e ... Mental Health Research Center, Tehran Psychiatric Institute, Mansoori Alley, Niayesh St., Sattarkhan St., Tehran, Iran, IR. ...
Objective: There are disparities in mental health services (MHS) utilization within and between p... more Objective: There are disparities in mental health services (MHS) utilization within and between populations and several factors are studied as its potential correlates. Identifying those correlates would help health policy makers to adjust service provision with characteristics of their community. To evaluate demographic, socioeconomic and system correlates of MHS utilization among married women from Tehran, Iran.
Transplantation Proceedings, 2007
Introduction. Several studies have noted that, despite beneficial correction of abnormalities of ... more Introduction. Several studies have noted that, despite beneficial correction of abnormalities of mineral metabolism after successful renal transplantation, renal functional recovery is incomplete. Also, persistence of hyperparathyroidism and metabolic acidosis among patients with chronic impairment of graft function together with the use of loop diuretics and immunosuppressive drugs with adverse effects may alter mineral metabolism. We determined calcium and phosphorus levels in recipients. Methods. This cross-sectional study enrolled 398 recipients in 2 medical centers in Iran from 1988 to 2004 to evaluate serum calcium and phosphorus levels after 1 month in relation to graft and patient survivals. Cyclosporine was the constant part of the immunosuppressive treatment in all study subjects. Results. The median follow-up time was 8 months (range, 1-180 months). One and 10-year survival rates of patients were 97.9% and 91.1%. Mean (SD) serum calcium levels before and after transplantation were 8.79 (1.26) and 8.50 (1.39) mg/dL, respectively (P ϭ .020). The mean (SD) phosphate levels before and after transplantation were 6.43 (2.42) and 3.64 (1.71) mg/dL, respectively (P ϭ .000). There was no significant difference in survival considering changes in serum calcium and phosphorus levels. There was no correlation between serum calcium and phosphorus level changes among study patients. Conclusions. Despite reports suggesting hypercalcemia as a posttransplantation finding, we did not observe this condition, but, consistent with other reports in this field, we observed a significant decrease in serum phosphorus levels showing correction of this mineral level.
Transplantation Proceedings, 2007
Background. Upper gastrointestinal (UGI) symptoms are common in uremic patients, and higher serum... more Background. Upper gastrointestinal (UGI) symptoms are common in uremic patients, and higher serum levels of urea have been suggested to be related to Helicobacter pylori (HP) colonization and UGI mucosal inflammation. Aim. The aim of this study was to compare HP infection and UGI endoscopic findings between uremic patients, renal transplant (RT) recipients, and controls. Methods. A total of 474 subjects (71 chronic renal failure [CRF], 73 hemodialysis [HD], 25 Tx, and 305 controls) from Baqyiatallah Hospital, Tehran, Iran were recruited between April 2002 and March 2004 for evaluation of dyspepsia, excluding those receiving any HP-eradication therapy. All subjects were examined for esophagus, stomach and duodenum mucosa, and infection with HP on 2 distinct tissue samples of the anthral region.
European Psychiatry, 2013
Journal of the American Geriatrics Society, 2011
The review found that evidence for the effectiveness of antidepressants in people with dementia a... more The review found that evidence for the effectiveness of antidepressants in people with dementia and depression was inconclusive and that larger studies were required. The review was generally well conducted and these findings appear reliable. Authors' objectives To evaluate the efficacy of antidepressants for people with depression and dementia. Searching MEDLINE (from 1966) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched to May 2010. Search terms were reported. The reference lists of articles retrieved were checked for further studies. Study selection Eligible were double-blinded placebo-controlled parallel-group randomised controlled trials (RCTs) of antidepressants marketed in the USA. Participants were required to have acute-phase depression and dementia diagnosed by established criteria. Required outcomes were response, remission, symptom change (using objective measures) and treatment discontinuation. Detailed definitions of outcomes were provided in the review. Bibliographic details Nelson JC, Devanand DP. A systematic review and meta-analysis of placebo-controlled antidepressant studies in people with depression and dementia.
Background. The Barkley Adult Attention Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV (BA... more Background. The Barkley Adult Attention Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV (BAARS-IV) was developed, and it demonstrated good psychometric properties. The BAARS-IV includes 27 questions on the symptoms of adult ADHD. The purpose of the present study is to investigate the psychometric testing of the Persian version of BAARS-IV among the elderlies in Tabriz City. Method. This cross-sectional study was conducted in Tabriz City-in the west of Iran-in 2015 via enrolling of 121 old-aged people. We did the process of translation and adaptation of BAARS-IV and examined its concurrent validity, internal consistency, and test-retest reliability. Result. The BAARS-IV demonstrated good internal consistency and test-retest reliability. Correlations between the BAARS-IV and the CAARS-S: SV were high and evidence supporting concurrent validity was revealed. Cronbach's alpha for the overall scale and subscales stood at 0.89, 0.81, 0.66, 0.56, and 0.82, respectively. Conclusion. The Persian BAARS-IV showed acceptable reliability and validity. BAARS-IV was determined to be composed of internally consistent and psychometrically sound items.
Transplantation Proceedings, 2007
Introduction. Hyperlipidemia is a multifactorial event that frequently develops following renal t... more Introduction. Hyperlipidemia is a multifactorial event that frequently develops following renal transplantation and may worsen the patient's prognosis. The aim of this study was to evaluate the incidence and concomitant factors for hyperlipidemia. Methods. We studied 687 renal transplant recipients from 1988 to 2004 using a cross-sectional design to determine the frequency of hypercholestrolemia and hypertriglyceridemia before and 1 month to 1 year after renal transplantation, to evaluate its relation to patient and graft prognosis in two medical centers in Iran. Cyclosporine was the constant part of immunosuppressive treatment in all study subjects. Results. One and 5-year graft survival times were 94.23% and 81.34%, respectively. The prevalence of hypercholestrolemia after transplantation was 59.9%. Mean (Ϯ 2 SE) serum cholesterol levels before and after transplantation were 161.15 Ϯ 3.81 and 213.83 Ϯ 4.53 mg/dL respectively (P ϭ .000). Triglycerides levels, were 159.99 Ϯ 13.08 and 196.28 Ϯ 19.6 mg/dL respectively. There was no significant correlation between cyclosporine dose, graft and patient survivals, and severity of hyperlipidemia (determined by cholesterol and triglyceride levels). Conclusions. Lipid metabolism abnormalities observed in this study were similar to other reports. There was no correlation with patient or graft survival. In addition, there may routes for development of hyperlipidemia other than adverse complications of immunosuppressive drugs.
... Masoud Ahmadzad Asl a, Ahmadreza Shamshiri b, Ahmad Hajebi *, Morteza Naserbakht c, Mohammadb... more ... Masoud Ahmadzad Asl a, Ahmadreza Shamshiri b, Ahmad Hajebi *, Morteza Naserbakht c, Mohammadbagher Saberi Zafarghandi d, Farnoush Davoudi e ... Mental Health Research Center, Tehran Psychiatric Institute, Mansoori Alley, Niayesh St., Sattarkhan St., Tehran, Iran, IR. ...
Objective: There are disparities in mental health services (MHS) utilization within and between p... more Objective: There are disparities in mental health services (MHS) utilization within and between populations and several factors are studied as its potential correlates. Identifying those correlates would help health policy makers to adjust service provision with characteristics of their community. To evaluate demographic, socioeconomic and system correlates of MHS utilization among married women from Tehran, Iran.
Transplantation Proceedings, 2007
Introduction. Several studies have noted that, despite beneficial correction of abnormalities of ... more Introduction. Several studies have noted that, despite beneficial correction of abnormalities of mineral metabolism after successful renal transplantation, renal functional recovery is incomplete. Also, persistence of hyperparathyroidism and metabolic acidosis among patients with chronic impairment of graft function together with the use of loop diuretics and immunosuppressive drugs with adverse effects may alter mineral metabolism. We determined calcium and phosphorus levels in recipients. Methods. This cross-sectional study enrolled 398 recipients in 2 medical centers in Iran from 1988 to 2004 to evaluate serum calcium and phosphorus levels after 1 month in relation to graft and patient survivals. Cyclosporine was the constant part of the immunosuppressive treatment in all study subjects. Results. The median follow-up time was 8 months (range, 1-180 months). One and 10-year survival rates of patients were 97.9% and 91.1%. Mean (SD) serum calcium levels before and after transplantation were 8.79 (1.26) and 8.50 (1.39) mg/dL, respectively (P ϭ .020). The mean (SD) phosphate levels before and after transplantation were 6.43 (2.42) and 3.64 (1.71) mg/dL, respectively (P ϭ .000). There was no significant difference in survival considering changes in serum calcium and phosphorus levels. There was no correlation between serum calcium and phosphorus level changes among study patients. Conclusions. Despite reports suggesting hypercalcemia as a posttransplantation finding, we did not observe this condition, but, consistent with other reports in this field, we observed a significant decrease in serum phosphorus levels showing correction of this mineral level.
Transplantation Proceedings, 2007
Background. Upper gastrointestinal (UGI) symptoms are common in uremic patients, and higher serum... more Background. Upper gastrointestinal (UGI) symptoms are common in uremic patients, and higher serum levels of urea have been suggested to be related to Helicobacter pylori (HP) colonization and UGI mucosal inflammation. Aim. The aim of this study was to compare HP infection and UGI endoscopic findings between uremic patients, renal transplant (RT) recipients, and controls. Methods. A total of 474 subjects (71 chronic renal failure [CRF], 73 hemodialysis [HD], 25 Tx, and 305 controls) from Baqyiatallah Hospital, Tehran, Iran were recruited between April 2002 and March 2004 for evaluation of dyspepsia, excluding those receiving any HP-eradication therapy. All subjects were examined for esophagus, stomach and duodenum mucosa, and infection with HP on 2 distinct tissue samples of the anthral region.
European Psychiatry, 2013