Faten Mohamed - Academia.edu (original) (raw)

Papers by Faten Mohamed

Asian Pacific Journal of Reproduction

Objective: To describe the breed predisposition, clinical diagnosis, pathological findings and th... more Objective: To describe the breed predisposition, clinical diagnosis, pathological findings and the surgical approach through excision of the hyperplasic mass from the vagina. Methods: Twenty five bitches of different breeds suffering from a protruded mass from the vulva were examined clinically, blood samples were collected to ensure the phase of estrus that were determined by evaluating the exfoliative vaginal epithelium, and a histopathological examination of the hyperplastic mass was done after its surgical excision. Results: The current work revealed that the maximum value of estradiol 17-B was in Alabai breed while the maximum value of progesterone was in Pit bull breed. And Pit bull breed showed cornification and stratification of the vaginal mucosa with abundant eosinophilic cytoplasm and regular round nuclei. Conclusions: As the vaginal hyperplasia is a crucial gynaecological problem that affects different breeds of bitches, the current work provides a comprehensive diagnosis of the case and illustrates the surgical interference for its excision.

Journal of Bioscience and Applied Research

Background: Diabetic nephropathy is a serious complication of both type 1 and type 2 diabetes. It... more Background: Diabetic nephropathy is a serious complication of both type 1 and type 2 diabetes. It's also called diabetic kidney disease (DKD). In the United States, about 1 in 3 people with diabetes have diabetic nephropathy. This necessitates identifying better biomarkers that diagnose diabetic nephropathy. The study aimed to evaluate tumor necrosis factor α (TNFα) and type IV collagen as potential biomarkers for the detection of diabetic nephropathy and its progression in patients with type 2 diabetes. Materials and Methods: A total of 88 subjects were included in this cross-sectional study. Patients were classified into three major groups; diabetics with DKD group (n=50), diabetics without DKD group (n=28), and healthy control group (n=10). TNFα and type IV collagen levels were measured in all subjects. The diagnostic value of single and combined TNFα and type IV collagen was assessed by the area under the receiver operating characteristic (AUC). Results: For discrimination between diabetics with DKD from healthy individuals, the most efficient marker was TNF-α (AUC= 0.81, 70% sensitivity, and 70% specificity. For discriminant between DM patients with DKD from DM patients without DKD, the most efficient marker was type IV collagen (AUC= 0.77, 69% sensitivity, and 73% specificity. Interestingly, we developed a new index for differentiating between DM and DM-DKD based on two blood markers (TNF-α and type IV collagen). The AUC of the developed index was 0.93; 0.79 for discriminated DM with DKD from DM BioBacta

Background: Although 3D printed photoinitiated resins are among the many materials utilized in pr... more Background: Although 3D printed photoinitiated resins are among the many materials utilized in prosthetic appliances today, biocompatibility for photocuring 3D printing materials for direct and long-term contacting with living body remain scarce. The purpose of this in vitro study was to evaluate the cell viability of human gingival fibroblasts after the exposure to two different 3D printed photoinitiated resins and compare it to the traditionally used heat polymerized acrylic resin for up to 7 days.Methods: This comparative in vitro study of sample size (n= 96), where the 3D printed resin disc samples (n= 64), were divided into two test groups, test group 1 (TG1) for NextDent Base resin (n= 32) and test group 2 (TG2) for Dental LT clear resin (n= 32), to be compared to Heat polymerized acrylic resin samples (Reference group (RG)) (n= 32). Human gingival fibroblasts were extracted from attached keratinized gingival tissues collected from healthy patient undergoing clinical crown len...

Journal of Agricultural Chemistry and Biotechnology

El-Minia Medical Bulletin, Mar 4, 2022

Background: Osteoarthritis is a painful chronic joint disease characterized by structural changes... more Background: Osteoarthritis is a painful chronic joint disease characterized by structural changes to the whole joint, including loss of articular cartilage, development of osteophytes, synovial inflammation, subchondral bone changes, meniscal damage, muscle weakness, and ligamentous laxity. Aim of the work: To detect osteopontine (OPN) in knee osteoarthritis. Methods: 60 patients diagnosed as primary knee OA fulfilling Arthritis Rheum 1986 OA classification criteria, And 60 healthy control were included. All patients subjected to through history taking and full examination, body mass index, plain x ray knees PA view to assess severity according to Kellgren and Laurence grading, plasma and synovial fluid OPN levels, and plasma OPN for control. Assessment of pain for OA patients by patient pain visual analogue scale (VAS) and for functional status by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), ESR,CRP were done. Results: there was significant difference between both groups regarding plasma osteopontine (p<0.0001), OPN levels in OA patients in plasma and synovial fluid was correlated with each other (p <0.0001), patient pain VAS, WOMAC score, K-L grading were correlated with plasma OPN levels with p value (0.001, <0.001, <0.001), and with synovial fluid OPN levels in primary OA patients with p value (0.008, <0.001, <0.001) respectively. ESR positively correlated with plasma OPN p=0.004. Conclusion: OPN is higher in OA patients more than control, and it is higher in synovial fluid than plasma in knee OA patients, OPN correlated with markers of systemic inflammation and has impact on functional status so it can be used as a diagnostic and prognostic factor in knee osteoarthritis.

Journal of Nuclear Technology in Applied Science, 2021

Water resources management is considered a major socioeconomic issue and a central component for ... more Water resources management is considered a major socioeconomic issue and a central component for future development; this implies an increasing demand for exploration of groundwater of high potentiality to cope with the excessive needs. In this work, Analytic Hierarchy Process (AHP) which is a widely used Multi-Criteria Decision Analysis (MCDA) has been used with Geographic Information System and Remote Sensing for classifying and mapping zones that intrinsically control and reflect groundwater recharge potentiality in the western area of El Minia Governorate, Upper Egypt. Six parameters of high attributes to groundwater recharge potentiality (Geology, Geomorphology, Slope, Lineaments Density, Drainage Density, and land use/land cover) have been selected. Assigned weights based on their relative importance to groundwater recharge, the weights were compared in a pair-wise matrix, the Eigen values were determined and the consistency ratio was calculated to validate the assigned weights; the ranges of these parameters are classed and rated. Overlay analysis was done to integrate the thematic layers of the parameters in Arc GIS domain for the development of a groundwater recharge potential map which has been verified using stable isotopic content (δ 18 O and δD) of 67 groundwater samples collected from the study Physico-Chemical and Organolyptical Characteristics Of Cake Fortified By Irradiated Broccoli (Brassica Oleracea L.Var Italica) Powder (15)

Minia Journal of Medical Research, 2019

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominately... more Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominately affects women. It is characterized by a broad spectrum of clinical manifestations. Adipokines are a diverse family of soluble mediators with a range of specific actions on the immune response. Among the various adipokines is Resistin. Methods: 26 patients with lupus nephritis with age ranged between 18-48 years and 20 healthy age, sex and BMI matched individuals were enrolled in this study. Full history, clinical examination and laboratory investigations were performed for all patients including serum resistin level. Results: The level of serum resistin was higher in the patients than the controls (p < 0.001). Also, Serum resistin level correlated positively with the levels of ESR (p< 0.001), CRP (p= 0.008). Serum resistin levels correlated negatively with levels of C3 (p< 0.001) and C4 (p< 0.001). Conclusion: Serum resisitin level can be used as a marker of inflammation in patients with lupus nephritis.

Aim of the study was to evaluate effectiveness of designed nursing guidelines on anxiety level fo... more Aim of the study was to evaluate effectiveness of designed nursing guidelines on anxiety level for patient undergoing EEG procedure Patients and Methods Aquasi-experimental study design was utilized in this study; hypothesis were formulated : The knowledge score for patients whom take designed nursing guidelines was higher than who didn't take. (2)The anxiety level for patients whom take guideline will be better than patient’s who didn't take the sample was ( 60) adult patients from both sex who were admitted in electroencephalogram unit at hospital . Two Tools were used interview Patients assessment questionnaire, and anxiety scale. Results showed a significant difference was found between the two groups as regard patient’s knowledge about EEG procedure in all items. A significant difference was found between the two groups regarding level of anxiety It was concluded that, level of knowledge for patients whom take designed nursing guidelines was higher than who didn't t...

INTRODUCTION: Complete bilateral cleft lip and palate CBCLP is considered the most difficult form... more INTRODUCTION: Complete bilateral cleft lip and palate CBCLP is considered the most difficult form of cleft cases nowadays. Nasoalveolar molding enhances the esthetic and functional results of cleft infants. NAM works on the principle of sculpting and molding of the alveolus and adjacent soft tissues. OBJECTIVES: The aim of this study was to assess the efficiency of a presurgical modified screw activated NAM appliance in retruding the premaxilla for CBCLP infants. MATERIALS AND METHODS: Fifteen CBCLP infant were included in the study. Preliminary maxillary impressions were made and the produced casts were scanned to obtain three-dimensional virtual image which was used to plan the design of the appliance. Two-piece acrylic active appliance with reverse expansion screw was used to retrude the premaxilla. The appliance was retained in place using niklel chromium side extension arms and head cap. When the cleft gap was closed to be suitable for surgical repair, primary lip repair was pe...

SUMMARY AND CONCLUSION T he human endometrium is a dynamic remodeling tissue undergoing more than... more SUMMARY AND CONCLUSION T he human endometrium is a dynamic remodeling tissue undergoing more than 400 cycles of regeneration, differentiation, and shedding during a woman’s reproductive years. The majority of endometrioid neoplastic lesions

Biochemistry Letters, 2020

Background: Management of high-risk non-muscle invasive bladder cancer is difficult, as no valida... more Background: Management of high-risk non-muscle invasive bladder cancer is difficult, as no validated tool exists to predict risk of recurrence. Urine has the potential to contain a variety of molecular markers that may be associated with tumors. Methods: The study included 3 groups: group 1comprised 100 patients diagnosed with non-muscle invasive bladder cancer (NMIBC). Each of Group 2 included 100 patients with other pathology rather than NMIBC. Group3 comprised 100 healthy persons. Group1 was subdivided into patients with and without recurrence. The patients with recurrent tumors were subclassified into single or multiple recurrences. Urinary markers: TERTand miR-34a were evaluated. Results: Higher urinary TERT > 3.2 and lower urinary miR34a < 0.85 were detected significantly in NMIBC group compared to controls. Conclusion: Urinary molecular biomarkers are reliable non-invasive tools for NMIBC detection and prediction of recurrence. Urinary TERT >3.2 and miR34a< 0.85 were significantly higher in patients with NMIBC in comparison with controls. Urinary TERT > 3.2 had the highest overall diagnostic accuracy for bladder cancer detection.

Minia Scientific Nursing Journal, 2021

Background: Total Quality Management represents a modern management philosophy, established due t... more Background: Total Quality Management represents a modern management philosophy, established due to the development in all aspects of life in today's world. Aim: To assess nursing staff awareness regarding challenges for applying Total Quality Management at Assuit University Hospital. Research design: A descriptive study convenience sample design with a sample contains all nurses working in General Surgical, Special Surgical, General Medical, and Special Medical departments at Assiut University Hospital with a total number of n= 219. Tools: Total Quality Management Challenges questionnaire is used. Results: Show that above one-third of them agree about all items of challenges for applying total quality management. Conclusion: No statistically significant differences between quality management challenges with personal and occupational characteristics of the studied nurses at Assuit University Hospital. Recommendations: Conduct an awareness sessions about total quality management between nurses at Assuit University Hospital; Conduct a total quality management training or program to all nurses at Assuit University Hospital, And the availability of quality assurance coordinator nurse in each department who works to implement quality policies in the departments and act as a link between the department and the Quality Committee.

Zagazig Journal of Agricultural Research, 2020

Survey and relative densities of coccinellid species and their parasitoids on wheat plants infest... more Survey and relative densities of coccinellid species and their parasitoids on wheat plants infesting with aphids at Pilbes district, Sharkia Governorate, Egypt was studied during 2015/16-2016/17 seasons. Summarized results show the following: Seven predaceous species belonging to family Coccinellidae viz., Coccinella undecimpunctata L., Coccinella septempunctata L., Coccinella 9-punctata L., Scymnus syriacus Mars, Scymnus interruptus (Goeze), Cydonia vicina isis Cr. and Cydonia vicina nilotica Muls were surveyed on wheat plants infesting with aphids. The general relative densities of the predators were 33.33, 20.29, 19.44, 12.35, 7.41, 4.01 and 2.47% of the total numbers of predators, respectively. C. undecimpunctata activity showed a distinct peak and two peaks of activity in the first and second seasons, respectively. The maximum total monthly counts of 83 and 77 predators were found during March, in the first and second seasons. Five species of hymenopterous parasitoids belong to three families were emerged from collected ladybeetles species, viz., Telenomus sp., Perilitus coccinellae (Schrank), Tetrastichus coccinellae Kurd., Tetrastichus principiae Domenichini and Tetrastichus sp. The egg parasitoid, Telenomus sp. came in the first rank, represented by 59.8%, followed by the larval parasitoid P. coccinellae 14.6%. The correlations between the total number of coccinellid predators and aphids were positive and highly significant in both seasons.

Journal of Agricultural Chemistry and Biotechnology, 2009

Two field experiments were conducted in a calcareous soil at El-Noubaria Research Station (ARC) d... more Two field experiments were conducted in a calcareous soil at El-Noubaria Research Station (ARC) during two successive seasons (2006 and 2007) to study the effect of biofertilizer inoculation with nitrogen fixing bacteria (Azospirillum lipoferum, Azotobacter chrococcoum, Bacillus polymyxa and Klebsiella pneumoniae), Ksolubilizing bacteria (Bacillus circulans) and Arbuscular mycorrhizal fungi on growth, yield and different storage periods of onion (Allium cepa) cultivar Giza 20. The important obtained results are as follows: Plant height and number of tubular leaves, plant dry weight and yield as growth parameters, nitrogenase enzyme activity, dehydrogenase enzyme activity and the percentage of AM-mycorrhizal infection as microbiological parameters and total nitrogen, phosphorus, potassium and carbohydrates as chemical parameters gave more vigor growth and yield due to the inoculation with N2-fixers + Bacillus circulans + AM-mycorrhizae + ½ dose of NPK fertilizers compared to control during both tested seasons and that also they recorded best plant growth, harvest bulbs yield (12.7 and 13.7 ton/fed), onion chemical properties as well as increased the tolerance against diseases and maintained healthy bulbs during the different storage periods.

Alexandria Dental Journal, Apr 1, 2020

INTRODUCTION: A well-constructed two-implant-assisted mandibular overdenture can be a successful ... more INTRODUCTION: A well-constructed two-implant-assisted mandibular overdenture can be a successful treatment option for completely edentulous patients as it helps improving the oral function and patient satisfaction through elimination of the fear of dislodgment during speech or mastication. Various attachment systems can be used for retaining mandibular overdentures such as bar, ball and socket, OT equator and locators. A new attachment system with metal to metal interface named Titach has evolved. During mastication, loads are transferred to alveolar bone surrounding the implants. OBJECTIVES: This study was done to compare the stress transmitted to peri-implant tissues of implant-assisted mandibular overdenture using two different attachment designs; Titach attachment and locator attachment. MATERIALS AND METHODS: A completely edentulous epoxy resin mandibular model was used in which two parallel dental implants were inserted at the canine region bilaterally. Sixteen mandibular implant-assisted overdentures were constructed forming two groups; each with different attachment design. Group I received 8 pairs of Titach attachment, while group II received 8 pairs of locator attachment. The difference in stress distribution was measured using strain gauges and compared between the two studied groups. Vertical load and oblique load (30 o and 45 o) of 50 and 100 N using the universal testing machine were applied bilaterally on the central occlusal fossae of mandibular first molars. RESULTS: There was no significant difference between group I and II upon application of vertical loading 50, 100N and 30 o oblique loading 50 N. However, group I showed lower strain values upon application of 30 o oblique loading 100N, 45 o oblique loading 50N and 100N. CONCLUSIONS: Titach attachment with metal to metal interface showed less strain values with favourable stress distribution when compared to zest anchor locator attachment with nylon interface for implant-assisted mandibular overdenture.

NeuroToxicology, 2020

The aim of the present study was to evaluate the toxicity of magnetic iron oxide nanoparticles (M... more The aim of the present study was to evaluate the toxicity of magnetic iron oxide nanoparticles (MIONs) which were synthesized using carob leaf extract on various brain areas of Wistar rats. Main methods: Carob leaf synthesized-MIONs were characterized using different techniques: Dynamic Light Scattering (DLS), Transmission Electron Microscope (TEM), UV-vis spectrophotometer, Fourier Transform infrared (FTIR), X-Ray Diffraction (XRD) and Atomic Force Microscope (AFM). The toxicity of MIONs in vivo was evaluated by: monitoring rat's body weight, measuring iron content in different brain areas, evaluating some oxidative stress parameters, estimating acetylcholinesterase (AChE) in addition to histopathological investigations. Key findings: The present study demonstrated no body weight changes of MIONs-treated rats. According to the conditions of the present study, the hippocampus and striatum were the most affected areas and demonstrated neuronal degeneration due to MIONs exposure. MIONs treatment of Wistar rats, also affected the iron homeostasis in both striatum and midbrain by decreasing iron content in these areas. The least affected areas were thalamus and cerebellum. The histopathological examination of brain areas demonstrated moderate neuronal degeneration in hippocampus and striatum, mild neuronal degeneration in cortex and slight degeneration in hypothalamus and pons-medulla areas were detected. Significance: The results suggested that MIONs have a toxic impact on different brain areas and the effect varies according to the brain area.

Biochemistry Letters, 2013

Background: Polymeric multilayer capsules are now being engineered to encapsulate various classes... more Background: Polymeric multilayer capsules are now being engineered to encapsulate various classes of drug molecules, by using polymers that are biodegradable or that can respond and release their payload in response to well-defined stimuli and are produced by stepwise adsorption of oppositely charged polymers onto the surface of colloidal particles followed by core dissolution, which is called Layer by Layer technique, Aim: The present study focuses on synthesis and characterization of polyelectrolyte multilayer microcapsules which was loaded with Bovine Serum Albumin and the cytotoxic effect of the microcapsules on the living cells was studied, Materials and methods: The microcapsules were fabricated by using Poly(allylamine) Hydrochloride (PAH) and Poly(styrenesulfonate) (PSS) as the counter charge polyelectrolytes and biocompatible calcium carbonate as the template which is highly promising to produce capsules for biological applications and loaded with bovine serum albumin (BSA) as a model drug, BSA labeled with fluorescein isothiocyanate (BSA-FITC), Calcium carbonate particles and the microcapsuls were characterized by SEM and TEM ,The effect of microcapsules on Madin Darby Bovine Kidney (MDBK) cell line were studied by using The 3-[4,5-dimethylthiazol-2-y]-2, 5-diphenyltetrazolium bromide MTT assay, Results: CaCO 3 microparticles are very convenient template for the preparation of polyelectrolyte microcapsules 1-4µm, preloading method is more effective than post loading method , Our results confirmed that this synthetic CaCO 3 microcapsules are cytocompatible, Conclusion: We thus have shown that the very easily prepared, stable, prototypical microcapsules composed of PSS/PAH are useful drug delivery agents for proof-of-principle drug delivery studies.

Egyptian Rheumatology and Rehabilitation, 2018

The aim of the study was to assess the usefulness of neuromuscular ultrasound in the diagnosis of... more The aim of the study was to assess the usefulness of neuromuscular ultrasound in the diagnosis of idiopathic carpal tunnel syndrome (CTS) and to determine the relationships of ultrasonographic measurements with the clinical severity and the electrophysiological grading scale. Patients and methods One hundred CTS diseased hands and 100 nondiseased hands were assessed clinically and by nerve conduction studies. We measured ultrasonographic crosssectional area (CSA) of the median nerve at various levels of the carpal canal (inlet and outlet), flattening ratio (FR), palmar bowing of the flexor retinaculum, wrist/ forearm ratio, as well as median nerve mobility and power doppler signals. Data from patients and controls were compared to determine the diagnostic relations and the grade of severity. Results Measures of CSA of the median nerve at the inlet and at the outlet, palmer bowing and inlet/forearm ratio in the CTS group were significantly higher than the control group (P<0.05); 50% of diseased hands showed restriction of mobility of the median nerve, while 31% had doppler signals. Positive correlations of ultrasonographic measurements with patient-oriented measures, clinical severity scale and electrophysiological grade were observed. Conclusion Ultrasonographic measurements of CSA at the inlet and flexor retinaculum have a relatively higher diagnostic accuracy than FR for CTS. The correlation between clinical scores, historical-objective-distribution scale, electrophysiological grade and ultrasonographic measurements reflects the usefulness of neuromuscular ultrasound in the diagnosis of idiopathic CTS.

Asian Journal of Research in Biochemistry, 2019

Heterocyclic compounds have a large spectrum of biological activities including antitumor activit... more Heterocyclic compounds have a large spectrum of biological activities including antitumor activity. The present study describes the cytotoxic effect of newly synthesized thiazole derivative (TD2) that can prove effective antitumor activity on both in vivo and in vitro studies. Objective: the essential objective of this research is to prove the cytotoxic effect of newly synthesized thiazole derivative (TD2) up on EAC bearing mice and many kinds of human cell lines. Materials and Methods: Antitumor activity of TD2 was examined on EAC in Swiss albino Mice at dose of 2.5 mg/kg. TD2 was injected for 10 following days after transplantation of tumor. After one day of last dose and 18 hours of fasting, 7 Mice were sacrificed and the remaining was kept to evaluate ILS %. Antitumor activity of TD2 was assessed by inspecting tumor volume, tumor weight, viable cell count and nonviable cell count, hematological, biochemical and antioxidant parameters of mice. Results: TD2 demonstrated an inhibit...

The Egyptian Journal of Radiology and Nuclear Medicine, 2017

Background: MS plaques display different pattern of enhancement with variable clinical course. Th... more Background: MS plaques display different pattern of enhancement with variable clinical course. The purpose is to assess the role of ADC value as a predictive for MS histologic changes with different enhancing pattern and its correlation with disease activity. Patients and methods: This prospective study included 28 chronic MS patients with 75 lesions, subjected for magnetic resonance imaging and ADC value measurement of the plaques and normally appearing white matter (NAWM) to be correlated with that of normal white matter (NWM) in 20 healthy controls. Results: T1-Hypointense and confluent lesions had statistical significant higher mean ADC value relative to the isointense and discrete lesions. Statistical significance difference was detected between mean ADC value of homogeneously enhancing lesions (HELs) and ring enhancing lesions (RELs) and between HELs and non-enhancing lesions (NELs), but no difference between NELs and RELs. Statistical significance difference was detected between ADC of NAWM relative to NWM of healthy controls. Conclusion: ADC value predicts histological changes in MS lesions. Pattern of enhancement doesn't correlate with neurologic deficits but ADC value is more valuable in assessing the disease activity.