Fatih Dogar - Academia.edu (original) (raw)

Papers by Fatih Dogar

Journal of Pediatric Orthopaedics B, 2023

Musculoskeletal infections, including septic arthritis, osteomyelitis, and soft tissue infections... more Musculoskeletal infections, including septic arthritis, osteomyelitis, and soft tissue infections, are critical morbidity factors for children and adolescents. This study investigated the role of D-dimer levels for diagnosing childhood musculoskeletal infections. This single-center prospective study was initiated in April 2020 following approval from the local ethics committee. The study included 54 children, divided into the infection group (n = 21), comprising patients who underwent surgical treatment for childhood musculoskeletal infections and had macroscopically visible purulent discharge during surgery, and the control group (n = 33), comprising healthy children. In the infection group, the mean values of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), plasma D-dimer, and white blood cell (WBC) were 39.42 ± 27.00 mm/h, 101.50 ± 76.90 mg/l, 2.34 ± 2.59 mg/l, and 15.55 ± 6.86 × 109/l, respectively. On comparison, the infection group showed higher levels of WBC, CRP, ESR, D-dimer, and neutrophil-to-lymphocyte ratio than the control group. When the D-dimer cutoff value of 0.43 mg/l was taken, it was observed that it had 95.2% sensitivity and 81.8% specificity. The area under curve (AUC) of the above-mentioned parameters calculated via receiver operating characteristic curves showed CRP levels as the optimum predictor of childhood musculoskeletal infections, followed by the ESR, plasma D-dimer, and WBC levels in descending order (AUC: 0.999, 0.997, 0.986, and 0.935, respectively). D-dimer is another test, which in combination with other conventional established tests (CRP and ESR) can be helpful in diagnosis of pediatric infection. We recommend the addition of D-Dimer to ESR, CRP, and WBC as a first-line investigation in cases with suspected pediatric musculoskeletal infections.

Medicine, Feb 19, 2021

Abstract Background: In the present study, we aimed to evaluate the effects of pulmonary rehabili... more Abstract Background: In the present study, we aimed to evaluate the effects of pulmonary rehabilitation on respiratory functions after the surgery on the basis of early radiological findings, pain degree, function, and satisfaction scores in operated patients with adolescent idiopathic scoliosis (AIS). Methods: Thirty patients with AIS were included in the present study, who were divided into 2 groups. Scoliosis surgery and diaphragmatic breathing and pursed lip exercises were applied in Group 1 (n = 15), whereas merely scoliosis surgery was applied in Group 2 (n = 15). Pulmonary functions, arterial blood gas analysis, Cobb and kyphosis angles, apical vertebral rotation, and apical vertebral translation were measured before and 1st and 6th months after the surgery. Using the SRS-30 test, the psychosocial statuses of the patients and their satisfaction degrees with surgery applied were measured before and after the surgery. Results: Six months after the surgery, the values of Cobb and kyphosis angles and apical vertebral rotations, and apical vertebral translation of the patients were determined to be significantly ameliorated, which is consistent with the literature. Forced vital capacity (l) and forced expiratory volume in the first second (l/s) were observed to be significantly improved in both groups after the surgery (respectively, P = .001, P = .014, P = .001, P = .005). In addition, the partial pressure of oxygen (pO2) value was found to be significantly increased 6 months after the surgery compared with that before the surgery in Group 2 (P = .022). SRS-30 showed that most of the scores in Group 1 were dramatically increased; a significant difference between the groups was not recorded. Conclusion: Patients with AIS have been found to be satisfied with the surgery. Conversely, pulmonary rehabilitation has been shown to slightly improve the respiratory functions in the patients with AIS, 1 and 6 months after the surgery.

Journal of Clinical Medicine Research, 2017

Background: We investigated the clinical and functional outcomes of chronic Achilles tendon ruptu... more Background: We investigated the clinical and functional outcomes of chronic Achilles tendon rupture reconstruction via the Lindholm technique and via the Vulpius' lengthening of the gastrocnemius. Methods: We evaluated 15 patients with chronic Achilles tendon rupture (Lindholm technique in eight patients and primary repair with the Vulpius technique in seven patients). In the final follow-up, the Hooker scale was used to measure the ankle functional capacity in all patients. The patients were evaluated on the basis of their capability to stand on tiptoe on the affected limb and the time required to return to pre-injury daily activities. Results: The mean follow-up time was 19.6 months (range, 12-38 months). The mean time to return to work and daily activity was 3.2 months. The mean calf atrophy at the end of follow-up was 1.2 cm (range, 0-2.5 cm). At the last follow-up visit, no patient had any limitation in the activities of daily living and the active and passive ankle range of motion was good. All patients were able to perform single-leg heel rises at the end of follow-up and the Hooker scores were excellent for 11 patients and satisfactory for four patients. Conclusion: The reconstruction of chronic Achilles tendon ruptures via the Lindholm technique or via the Vulpius technique is associated with good clinical and functional outcomes.

$Research paper thumbnail of A multicenter intertrochanteric fracture study in the elderly: Hemiarthroplasty versus proximal femoral nailing$

Joint diseases and related surgery, Jun 25, 2020

With the aging population, the incidence rate of osteoporosis has been rapidly increasing. [1] Th... more With the aging population, the incidence rate of osteoporosis has been rapidly increasing. [1] These fractures are predicted to reach 2.6 million in 2025 and 4.5 million in 2050 worldwide. [2] The incidence of these fractures, which frequently occur due to falls, is two-three times higher in females than in males. [3] Intertrochanteric fractures, which are usually unstable, can only be treated surgically. [4] The key point of the surgical treatment is stable fixation and early mobilization with full-weight bearing. However, this is not always as easy as it seems. Most of the patients are elderly, osteoporotic, with additional morbidity and limited mobilization, and prone to complications. [5,6] Therefore, there is no consensus regarding the treatment of Objectives: This study aims to compare the clinical and functional results of intertrochanteric femoral fractures treated with bipolar hemiarthroplasty (BHA) or proximal femoral nailing (PFN) in elderly patients. Patients and methods: This multicenter, prospectively followed-up, retrospectively compared cohort-type study included 308 patients (81 males, 227 females; mean age 78.4±7.2 years; range, 65 to 95 years) who were treated with BHA or PFN for intertrochanteric fractures by five orthopedic surgeons in four provinces and seven clinics between January 2014 and May 2018. Clinical follow-up was performed at third week, third and sixth months, and at the end of the first and second years. The American Society of Anesthesiologists for preoperative status, Singh index for bone quality, and Harris Hip Score (HHS) for functional outcomes were evaluated. Results: While 156 patients (38 males, 118 females; mean age 77.7±5.9) were treated with BHA, 152 patients (43 males, 109 females; mean age 79±6.1) were treated with PFN. While there was no significant difference between the two groups in terms of total HHS, a significant difference was found in the sub-parameters (p<0.001). Good and excellent results were found in 78.2% of BHA and 86.2% of PFN patients. Mortality rates were similar at the end of two years (14% and 13.6%, respectively). Conclusion: In general, clinical and functional outcomes of BHA and PFN are similar. The rates of pulmonary embolism and deep vein thrombosis are significantly higher in BHA. However, BHA is advantageous in terms of operation time and early weight bearing compared to PFN.

Acta medica alanya, Jun 21, 2023

Çalışma, biseps tendon bozuklukları ile ilişkili omuz şikayetleri olan hastalar için oluşturulan ... more Çalışma, biseps tendon bozuklukları ile ilişkili omuz şikayetleri olan hastalar için oluşturulan web sitelerinin kalite, yeterlilik ve okunabilirliğini incelemeyi amaçlamıştır. Yöntem: Amerika Birleşik Devletleri'nde en çok kullanılan arama motorlarında (Google, Yahoo ve Bing) 'omuz yaralanması' , 'biseps tendiniti' ve 'biseps tendon rüptürü' terimleri arandı. Hastaları bilgilendirmek için tasarlanmış 147 web sitesi çalışmaya dahil edildi. Kalite, popülerlik, yeterlilik ve güvenilirlik ölçüldü. Bulgular: Sağlık profesyonelleri tarafından içerik oluşturulan web sitelerinin Flesch okuma kolaylığı puanları, oluşturmayanlara göre önemli ölçüde düşüktü; aksine, Flesch-Kincaid sınıf düzeyi (FKGL) ve Koleman-Liau endeksi skorları anlamlı olarak daha yüksekti (p<0.05). Sağlık profesyonelleri tarafından oluş turulan web sitesinde global kalite puanları ve özgünlük pu anları daha yüksekti (p<0.05). Gunning Fog, FKGL, Gobbledygook'un Basit Ölçüsü, Otomatik okunabilirlik endeksi ve doğrusal yazma for mülü puanları, HON koduna sahip web sitelerinin HON kodu olmayanlara göre daha düşüktü. Ayrıca özgünlük puanı ve APR puanları, HONcode'lu web sitelerinde HONcode'suz web sitele rine göre daha düşüktü (p<0.05). Sonuç: Sağlık profesyonelleri tarafından hazırlanan HON kodlu web siteleri biseps tendon bozukluğu olan hastalara yeterli ve kaliteli bilgi sağlayabilir. Biseps tendon bozuklukları için mevcut olan web içeriği, önerilen okuma seviyesinin üzerindedir. Sağlık profesyonelleri içeriğin okunabilirliğini artırmaya teşvik edilmelidir.

Journal of surgery and medicine, Jan 31, 2020

Aim: Periprosthetic joint infection after total hip or knee arthroplasty is one of the most feare... more Aim: Periprosthetic joint infection after total hip or knee arthroplasty is one of the most feared complications. The aim of this study was to evaluate the efficacy of inflammatory biomarkers in identifying periprosthetic joint infection. Methods: This cross-sectional and bi-centered study included 131 patients, who had suspected prosthesis infection and underwent threephase bone scintigraphy. Patients were divided into three groups according to the Musculoskeletal Infection Society criteria and scintigraphic study results: Group 1 comprised cases with prosthetic infection, Group 2 included aseptic loosening cases and Group 3 included cases with healthy prostheses. Results: White blood cell average was 11.5 (3.2) 10 9 /L in group 1, 8. (2.1) 10 9 /L in group 2 and 7.9 (2.1) 10 9 /L in group 3, among which it was significantly higher in Group 1 compared to Groups 2 and 3, (P<0.001, P<0.001), while there was no significant difference between groups 2 and 3 (P=0.753). C reactive protein values (CRP) were 46.6 (50.0) mg/L in group 1, 18.8 (17.5) mg/L in group 2 and 15.3 (17.1) mg/L in group 3, significantly higher in group 1 than the other groups (P<0.001, P<0.001), and similar in Groups 2 and 3 (P=0.876). The mean erythrocyte sedimentation rate values did not differ significantly between the groups. Conclusion: The use of three-phase bone scintigraphy and inflammatory biomarkers such as C reactive protein and white blood cell have been shown to be effective in predicting prosthetic infection.

Journal of Orthopaedic Surgery and Research, Jan 7, 2021

Introduction: Developmental dysplasia of the hip (DDH) is a common disorder and associated with s... more Introduction: Developmental dysplasia of the hip (DDH) is a common disorder and associated with significant morbidity of the hip joint. Several risk factors have been identified for DDH. The aim of this study is to investigate whether vitamin D and vitamin D receptor (VDR) levels differ in children with DDH and whether they have an effect on DDH development. Materials and methods: A total of 40 (17 males, 23 females; 9 right hips, 16 left hips, 15 bilateral hips) children who were treated for developmental dysplasia and 40 (23 males, 17 females) healthy children without any musculoskeletal system and metabolic disorders were included in this study between January and June 2019. Blood samples from the DDH and control groups of children were collected to measure the serum levels of vitamin D, VDR, calcium (Ca), phosphorus (P), and alkaline phosphatase (ALP). The levels of Ca, P, and ALP were analyzed using the automated standard spectrophotometric laboratory method. The levels of vitamin D and VDR in the samples were analyzed using enzyme-linked immunoassay. Results: There were no significant differences in the serum levels of Ca, P, ALP, and vitamin D between the DDH and healthy groups (Ca 9.96 ± 0.47 vs. 9.92 ± 0.48 mg/dL, respectively, p = 0.721; P 5.3 ± 0.94 vs. 4.82 ± 0.88 mg/dL, respectively, p = 0.23; ALP 252.22 ± 170.15 vs. 245.3 ± 130.93 U/L, respectively, p = 0.839). However, serum VDR levels were significantly lower in children in the DDH group (5.77 ± 3.51 ng/mL) than in the healthy control group (9.25 ± 6.43 ng/mL) (p = 0.004). Conclusions: In conclusion, we believe that low VDR levels can affect DDH regardless of the serum levels of Ca, P, ALP, and vitamin D. More comprehensive studies involving parents are needed to understand whether VDR levels mediate genetic transmission in DDH or not.

Therapeutics and Clinical Risk Management, Apr 1, 2016

Dysplasia epiphysealis hemimelica, also termed Trevor disease, is a rare disorder that, although ... more Dysplasia epiphysealis hemimelica, also termed Trevor disease, is a rare disorder that, although benign in nature, can be locally aggressive, particularly when affecting the ankle joint, which is the joint most frequently affected, followed by the knee. The female:male ratio is 1:3, and it is generally diagnosed between 2 and 14 years of age. Surgical treatment with complete resection is recommended before irreversible joint damage and deformity occurs. We presented a case in which dysplasia epiphysealis hemimelica was diagnosed on the medial aspect of a right ankle joint.

Annals of Clinical and Analytical Medicine

$Research paper thumbnail of High volume pericapsular nerve group (PENG) block for acetabular fracture surgery: A new horizon for novel block$

Journal of Clinical Anesthesia, Jun 1, 2020

Journal of the American Podiatric Medical Association, Nov 1, 2022

Indian Journal of Surgery, Aug 2, 2022

KSÜ Tıp Fakültesi dergisi, Jul 7, 2021

Bu çalışmanın amacı, Karpal Tünel Sendromu (KTS) ile anjiyogenez, tromboz, immünite ve inflamasyo... more Bu çalışmanın amacı, Karpal Tünel Sendromu (KTS) ile anjiyogenez, tromboz, immünite ve inflamasyonla sonuçlanan ortalama trombosit hacmi (MPV) arasındaki ilişkiyi değerlendirmektir Gereç ve Yöntemler: 2013 ve 2019 yılları arasında, 1660 hastaya mini-açık dekompresyon uygulandı ve sırasıyla 1056 sağlıklı birey kontrol grubu olarak retrospektif çalışmaya dahil edildi. Dışlama kriterleri sağlandıktan sonra 166 KTS hastası (141 kadın, 25 erkek) ve 156 kontrol hastası (80 kadın, 76 erkek) olarak iki grup belirlendi. KTS ve kontrol gruplarında, 12 saat aç kalındıktan sonar alınan venöz kan örneklerinden ortalama trombosit hacmi (MPV), trombositsayısı (PLT), trombosit dağılım genişliği (PDW), beyaz kan hücre (WBC) sayısı, hemoglobin (Hb), ESR ve CRP düzeyleri elde edildi ve hastane veri tabanında geriye dönük olarak kaydedildi. Ayrıca KTS grubundaki hastalardan postoperatif 6. ve 12. ay kontrollerinde kan örnekleri alınarak operasyon öncesi çalışılan değerler dosyadan tekrardan kaydedildi. Bulgular: KTS hastaları arasında, ameliyat sonrası 6 ayda ortalama MPV'de bazal değere kıyasla anlamlı bir fark vardı (p = 0,027). Ortalama MPV'de 1. yılda bazal değere göre anlamlı bir fark bulunmadı (p = 0,70). Ek olarak, KTS' li hastalar ve kontrol grubundaki hastalar arasında MPV değerlerinde veya diğer kan parametrelerinde (trombosit sayısı, beyaz kan sayımı, trombosit dağılımı genişliği ve hemoglobin) anlamlı bir fark bulunmadı. Sonuç: Çalışmamızda KTS ile MPV arasında önemli bir ilişki bulunmadığını tespit ettik. Bu konuyu aydınlatmak için daha büyük örneklem büyüklüğüne ve geniş prospektif çalışmaların gerekli olduğuna inanıyoruz.

Joint diseases and related surgery, Dec 27, 2022

Although there are no underlying metabolic diseases for reasons such as unfamiliar training patte... more Although there are no underlying metabolic diseases for reasons such as unfamiliar training patterns, anatomy and biomechanical causes with the increase of sporting activities, Achilles tendon ruptures increase in all age groups. [1] Open and percutaneous surgical and conservative techniques are used to repair ruptured Achilles tendon. The treatment goals of a ruptured Achilles tendon are to lengthen the tendon and to increase the force and power of the gastrocnemius and soleus muscles. [2] Regardless of the treatment method, a medical support independent of these treatment options is needed to reduce early complications. Levocarnitine (L-carnitine) is an amino acid added with trimethyl that assists long-chain fatty acids Objectives: In this experimental study, we aimed to analyze the effects of levocarnitine (L-carnitine) on tendon healing after surgical repair of Achilles tendon rupture in a rat model. Materials and methods: The study included 40 Wistar Albino rats divided into four groups: Group 1, neither surgical intervention nor substance applications were performed for the Achilles tendons. In the other groups, the right Achilles tendons were cut using a scalpel and repaired with a modified Kessler-type technique with 3/0 monofilament polydioxanone suture. In Group 2, the rats did not receive any additional treatment, except for surgical repair. In Group 3, the same volume similar to Group 4 of saline solution was administered intraperitoneally for seven days. In Group 4, each rat received 300 mg/kg of L-carnitine intraperitoneally for seven days. At Week 6, all rats were sacrificed. All right Achilles tendons were used for biomechanical tests and histopathological evaluations. Biochemical analysis of the matrix metalloproteinase was also performed using the blood specimens. Results: There were no significant differences among the groups in terms of the histopathological parameters. Although the mean matrix metalloproteinase level was low in the L-carnitine group, it did not reach statistical significance. A significant increase in maximum force, tensile strength, and strength to 2-mm gap was observed in the L-carnitine group. Conclusion: The significant effects of L-carnitine on biomechanical parameters may indicate favorable effects on Achilles tendon healing in rats by reducing matrix metalloproteinase 2 and 9. To improve Achilles tendon healing, further investigation for these markers is needed. Since the effects of L-carnitine on the Achilles tendon cannot be clearly distinguished histopathologically, further studies involving L-carnitine-induced effects are warranted.

Journal of the American Podiatric Medical Association, Oct 12, 2022

$Research paper thumbnail of Rare coracoid fractures presenting with superior shoulder suspensory complex injury: A case series$

Joint diseases and related surgery, Nov 19, 2021

The coracoid process is an important anatomical landmark serving as an attachment site for the sh... more The coracoid process is an important anatomical landmark serving as an attachment site for the short head of the biceps brachii, coracobrachialis, and pectoralis minor muscles and coracoacromial, coracohumeral, trapezoid, and conoid ligaments. [1] Another important function of the coracoid process is that it contributes to the anterior superior stability of the shoulder joint by forming the coracoacromial arch and the superior shoulder suspensory complex (SSSC). [2,3] Coracoid fractures are usually associated with other fractures and dislocations of the scapula and the shoulder area, and they are occasionally observed after high-energy traumas. [3,4] While coracoid fractures constitute 3 to 13% of scapular fractures, they constitute 1% of all fractures and 5% of shoulder fractures. [1,3-8] Although coracoid fractures are rare fractures, their treatment is critical as they form the coracoacromial arch and superior shoulder suspensory complex (SSSC), which are important structures for shoulder biomechanics. In this case series, clinical, radiological, and demographic characteristics of three male patients who received treatment due to coracoid fracture presenting with traumatic injuries were discussed. The fractures were classified according to the Ogawa and Eyres classifications, and fracture fixation was achieved surgically with the cannulated screws. All patients had a right coracoid fracture. The Constant-Murley Score and the Disabilities of the Arm, Shoulder and Hand scores the patients in the final follow-up visit at 12 months were calculated. In conclusion, good clinical and functional outcomes can be achieved by anatomical reduction and fixation through surgery for displaced coracoid fractures presenting with multiple traumatic injuries located in multiple regions of the SSSC.

$Research paper thumbnail of Effects of focal cerebellar injury on fracture healing and oxidative stress in rat model: an experimental animal study$