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Papers by Felícitas Díaz-Flores Estévez
Medicina Clínica (English Edition)
Journal of Pharmaceutical and Biomedical Analysis, Jun 1, 2002
A fast, selective and economical method for the determination of retinol and a-tocopherol is pres... more A fast, selective and economical method for the determination of retinol and a-tocopherol is presented. Both vitamins are separated by high-performance liquid chromatography (HPLC) in less than 4 min using an isocratic elution with methanol. The robustness of the method was checked in real samples, obtaining relative standard deviation lower than 3%. The described method was satisfactorily applied to serum samples proceeding of patients enrolled in a METHADONE maintenance treatment program. The retinol concentrations in the serum of these patients fell into the normal interval of concentrations; however, the serum a-tocopherol contents were higher than the normal values.
Revista Espanola De Enfermedades Digestivas, 2022
Manuel. Hepatitis C virus infection screening reduces mortality and is cost-effective independent... more Manuel. Hepatitis C virus infection screening reduces mortality and is cost-effective independently of the intervention test. Rev Esp Enferm Dig 2022.
International Journal of Dermatology
Revista espanola de salud publica, 2021
Newborn Screening Programs (NSP) in Spain were born in the city of Granada in 1968. Till the 1980... more Newborn Screening Programs (NSP) in Spain were born in the city of Granada in 1968. Till the 1980s, they were developed around the so-called "National Plan for Preventing Subnormality", covering up to 30% of the Spanish newborns. From 1982, when the health system management was transferred to the different autonomous regions, the NSP began to expand, and the bases to transform them into an organized and multidisciplinary activity, integrated and coordinated from the National Health System were settled. Despite this expansion, it is not until the 1990s when their coverage reaches almost 100% newborns in Spain. NSP grew up asymmetrically across the different autonomous regions. In 2005 and 2006 the scientific societies SEQC (Spanish Society of Clinical Chemistry) and AECNE (Spanish Society of Newborn Screening), coordinated by the Health Promotion Area of the General Directorate of Public Health, gathered together the necessary information to elaborate a report on the NSP in...
Análisis clínicos: órgano de expresión científica y profesional de la Asociación Española de Farmacéuticos Analistas, 1996
Biblioteca de la Universidad Complutense de Madrid, Base de datos de artículos de revistas, ...
Análisis clínicos: órgano de expresión científica y profesional de la Asociación Española de Farmacéuticos Analistas, 1996
... Resultado de la búsqueda, 1-1/1, Seleccionar todos Título: Puesta a punto de una técnica para... more ... Resultado de la búsqueda, 1-1/1, Seleccionar todos Título: Puesta a punto de una técnica para cuantificación de lipoproteina por nefelometria Autores: Vera Gonzalez, A.; Díaz-Flores Estevez, F. Revista: Análisis Clínicos, 1996 ABR-JUN; XXI (83) Página(s): 60 ISSN: 02124572. ...
Revista Espanola De Salud Publica, 2021
espanolLos Programas de Cribado Neonatal (PCN) nacen en Espana en Granada en el ano 1968. Posteri... more espanolLos Programas de Cribado Neonatal (PCN) nacen en Espana en Granada en el ano 1968. Posteriormente, y hasta los anos 80, se fueron desarrollando en torno al llamado “Plan Nacional de Prevencion de la Subnormalidad” con una cobertura cercana al 30% de los recien nacidos espanoles. A partir de 1982, con el inicio de la gestion de la sanidad a las comunidades autonomas (CCAA), los PCN se expandieron y se comenzaron a sentar las bases para que estos se convirtieran en una actividad organizada y multidisciplinar, integrados y coordinados desde el Sistema de Salud. A pesar de dicha expansion no es hasta el inicio de la decada de los 90 cuando se consigue una cobertura proxima al 100% de los RN en Espana. Los PCN fueron creciendo de forma muy asimetrica en las diferentes CCAA y en los anos 2005 y 2006 las Sociedades Cientificas SEQC (Sociedad Espanola de Quimica Clinica) y AECNE (Asociacion Espanola de Cribado Neonatal), con la coordinacion del Area de Promocion de la Salud de la Dir...
Journal of Applied Biomedicine, 2005
The biochemical and haematological parameters of nutritional interest were determined in the seru... more The biochemical and haematological parameters of nutritional interest were determined in the serum of opiate addicts in order to compare them with those obtained in healthy subjects. The blood of 106 opiate addicts in detoxification treatment (n=19) or in Methadone Maintenance Treatment Program (MMTP) (n=87) was studied. Opiate addicts presented lower levels in the number of red cells, cholesterol, albumin, retinol, α-tocopherol, folic acid, K and Se and higher levels in the number of leukocytes, GOT, GPT and Na, than the control group. The opiate addicts in MMTP had higher levels of glucose, triglycerides, Mg and P than the opiate addicts in the detoxification treatment and control groups. Significant correlations between the three vitamins (folic acid, retinal and α-tocopherol) were observed and the graphic representations suggest a biochemical differentiation between opiate addicts and healthy subjects. Factor analysis made it possible to select seven factors explaining 66.2% of the total variance, and representing the first and fourth factor, opiate addicts tended to separate from the control group.
Medicina Clínica (English Edition)
Journal of Pharmaceutical and Biomedical Analysis, Jun 1, 2002
A fast, selective and economical method for the determination of retinol and a-tocopherol is pres... more A fast, selective and economical method for the determination of retinol and a-tocopherol is presented. Both vitamins are separated by high-performance liquid chromatography (HPLC) in less than 4 min using an isocratic elution with methanol. The robustness of the method was checked in real samples, obtaining relative standard deviation lower than 3%. The described method was satisfactorily applied to serum samples proceeding of patients enrolled in a METHADONE maintenance treatment program. The retinol concentrations in the serum of these patients fell into the normal interval of concentrations; however, the serum a-tocopherol contents were higher than the normal values.
Revista Espanola De Enfermedades Digestivas, 2022
Manuel. Hepatitis C virus infection screening reduces mortality and is cost-effective independent... more Manuel. Hepatitis C virus infection screening reduces mortality and is cost-effective independently of the intervention test. Rev Esp Enferm Dig 2022.
International Journal of Dermatology
Revista espanola de salud publica, 2021
Newborn Screening Programs (NSP) in Spain were born in the city of Granada in 1968. Till the 1980... more Newborn Screening Programs (NSP) in Spain were born in the city of Granada in 1968. Till the 1980s, they were developed around the so-called "National Plan for Preventing Subnormality", covering up to 30% of the Spanish newborns. From 1982, when the health system management was transferred to the different autonomous regions, the NSP began to expand, and the bases to transform them into an organized and multidisciplinary activity, integrated and coordinated from the National Health System were settled. Despite this expansion, it is not until the 1990s when their coverage reaches almost 100% newborns in Spain. NSP grew up asymmetrically across the different autonomous regions. In 2005 and 2006 the scientific societies SEQC (Spanish Society of Clinical Chemistry) and AECNE (Spanish Society of Newborn Screening), coordinated by the Health Promotion Area of the General Directorate of Public Health, gathered together the necessary information to elaborate a report on the NSP in...
Análisis clínicos: órgano de expresión científica y profesional de la Asociación Española de Farmacéuticos Analistas, 1996
Biblioteca de la Universidad Complutense de Madrid, Base de datos de artículos de revistas, ...
Análisis clínicos: órgano de expresión científica y profesional de la Asociación Española de Farmacéuticos Analistas, 1996
... Resultado de la búsqueda, 1-1/1, Seleccionar todos Título: Puesta a punto de una técnica para... more ... Resultado de la búsqueda, 1-1/1, Seleccionar todos Título: Puesta a punto de una técnica para cuantificación de lipoproteina por nefelometria Autores: Vera Gonzalez, A.; Díaz-Flores Estevez, F. Revista: Análisis Clínicos, 1996 ABR-JUN; XXI (83) Página(s): 60 ISSN: 02124572. ...
Revista Espanola De Salud Publica, 2021
espanolLos Programas de Cribado Neonatal (PCN) nacen en Espana en Granada en el ano 1968. Posteri... more espanolLos Programas de Cribado Neonatal (PCN) nacen en Espana en Granada en el ano 1968. Posteriormente, y hasta los anos 80, se fueron desarrollando en torno al llamado “Plan Nacional de Prevencion de la Subnormalidad” con una cobertura cercana al 30% de los recien nacidos espanoles. A partir de 1982, con el inicio de la gestion de la sanidad a las comunidades autonomas (CCAA), los PCN se expandieron y se comenzaron a sentar las bases para que estos se convirtieran en una actividad organizada y multidisciplinar, integrados y coordinados desde el Sistema de Salud. A pesar de dicha expansion no es hasta el inicio de la decada de los 90 cuando se consigue una cobertura proxima al 100% de los RN en Espana. Los PCN fueron creciendo de forma muy asimetrica en las diferentes CCAA y en los anos 2005 y 2006 las Sociedades Cientificas SEQC (Sociedad Espanola de Quimica Clinica) y AECNE (Asociacion Espanola de Cribado Neonatal), con la coordinacion del Area de Promocion de la Salud de la Dir...
Journal of Applied Biomedicine, 2005
The biochemical and haematological parameters of nutritional interest were determined in the seru... more The biochemical and haematological parameters of nutritional interest were determined in the serum of opiate addicts in order to compare them with those obtained in healthy subjects. The blood of 106 opiate addicts in detoxification treatment (n=19) or in Methadone Maintenance Treatment Program (MMTP) (n=87) was studied. Opiate addicts presented lower levels in the number of red cells, cholesterol, albumin, retinol, α-tocopherol, folic acid, K and Se and higher levels in the number of leukocytes, GOT, GPT and Na, than the control group. The opiate addicts in MMTP had higher levels of glucose, triglycerides, Mg and P than the opiate addicts in the detoxification treatment and control groups. Significant correlations between the three vitamins (folic acid, retinal and α-tocopherol) were observed and the graphic representations suggest a biochemical differentiation between opiate addicts and healthy subjects. Factor analysis made it possible to select seven factors explaining 66.2% of the total variance, and representing the first and fourth factor, opiate addicts tended to separate from the control group.