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Research paper thumbnail of Complementary identification of multiple fluxdistributions and multiple metabolic pathways

Cell robustness and complexity have been recognized as unique features of biological systems. Suc... more Cell robustness and complexity have been recognized as unique features of biological systems. Such robustness and complexity of metabolic-reaction systems can be explored by discovering, or identifying, the multiple flux distributions (MFD) and redundant pathways that lead to a given external state; however, this is exceedingly cumbersome to accomplish. It is, therefore, highly desirable to establish an effective computational method

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Research paper thumbnail of Assessment of Sustainability-Potential:  Hierarchical Approach

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Research paper thumbnail of Reduced super-structure for a separation network comprising separators effected by different methods of separation

ABSTRACT Among separation systems, the ones comprising separators effected by different separatio... more ABSTRACT Among separation systems, the ones comprising separators effected by different separation methods have been steadily gaining attention lately. Our earlier work has revealed that it is exceedingly complicated to optimally synthesize via super-structure any of these separation networks featuring simple and sharp separators, multiple feed and product streams, and mixed products. This complication can be substantially lessened by constituting a reduced super-structure for the network of interest. This super-structure profoundly simplifies the mathematical model and decreases the computational time required to yield the results identical to those obtained from the original super-structure.

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Research paper thumbnail of Project no.: 262205 Project full title: Intensified Heat Transfer Technologies for Enhanced Heat Recovery Project Acronym: INTHEAT Deliverable no.: D6. 2 Title of the deliverable: Report on the performed marketing activities and commercialisation

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Research paper thumbnail of In-Depth Study and Comparison of S-Graph Framework and Precedence Based MILP Formulations for Batch Process Scheduling

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Research paper thumbnail of Applications of P-Graphs for Enhancing Sustainability of Industrial Plants

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Research paper thumbnail of Use the P-graph Framework to Design Supply Chains for Sustainability

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Research paper thumbnail of Risk reduction through waste minimizing process synthesis

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Research paper thumbnail of On the reformulation of some classes of PNS-problems as set covering problems.(Working paper of the Laboratory of Operations Research and Decision Systems,(LORDS) WP 97-1.)

ABSTRACT Process network synthesis (PNS) has enormous practical impact; however, its solution is ... more ABSTRACT Process network synthesis (PNS) has enormous practical impact; however, its solution is difficult in general. This experience has been recently reasoned by Blázsik and Imreh who pointed out that PNS-problems are NP-hard. They proved that a simple subclass of PNS-problems is equivalent to the class of set covering problems. In the present paper, it is shown that more general classes of PNS-problems can also be reformulated as set covering problems. This enables the sophisticated techniques developed for solving set covering problems also to be applied for solving some PNS-problems.

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Research paper thumbnail of Part special issue-PRES'99 (2nd Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction)

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Research paper thumbnail of Using S-graph to adress uncertaintly in batch plants

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Research paper thumbnail of Current Opinion in Chemical Engineering

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Research paper thumbnail of Design of nonconventional processes Editorial overview

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Research paper thumbnail of Scheduling of Automated Wet-Etch Stations

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Research paper thumbnail of Editorial overview: Process systems engineering: Design for sustainability

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Research paper thumbnail of Building-evacuation-route planning via time-expanded process-network synthesis

ABSTRACT A method and software are proposed for optimal building-evacuation-route planning in ter... more ABSTRACT A method and software are proposed for optimal building-evacuation-route planning in terms of identifying evacuation routes and scheduling of evacuees on each route. First, the building-evacuation routes are represented by a P-graph, which gives rise to a time-expanded process-network synthesis ( ) problem that can be algorithmically solved by the P-graph framework. In the proposed method, each location and passage in the building is given by a set of attributes to be taken into account in the evacuation-route planning. The evacuation time is calculated as a minimum cost of the corresponding . In addition to the globally optimal solution, the P-graph framework provides the n-best sub-optimal solutions. The validity of the proposed method is illustrated by two examples.

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Research paper thumbnail of Designing Sustainable Energy Supply Chains by the P-graph Method for Minimal Cost, Environmental Burden, Energy Resources Input

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Research paper thumbnail of PRES conferences: Energy efficiency and environmental protection

... Heriberto Cabezas David Kukulka Martin Sponar Antonio Espuna Thoko Majozi Krzysztof Urbaniec ... more ... Heriberto Cabezas David Kukulka Martin Sponar Antonio Espuna Thoko Majozi Krzysztof Urbaniec Michalis Georgiadis Francois Marechal Spyros Voutetakis Andrzej Go´rak Josua P Meyer G+unter Wozny Kentaro Hirata Simira Papadopoulou Dominic Foo Chwan Yee ...

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Research paper thumbnail of Combinatorially accelerated branch-and-bound method for solving the MIP model of process network synthesis

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Research paper thumbnail of Workshop for Process Integration and Intensification, Process Optimisation and Regional Sustainability

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Research paper thumbnail of Complementary identification of multiple fluxdistributions and multiple metabolic pathways

Cell robustness and complexity have been recognized as unique features of biological systems. Suc... more Cell robustness and complexity have been recognized as unique features of biological systems. Such robustness and complexity of metabolic-reaction systems can be explored by discovering, or identifying, the multiple flux distributions (MFD) and redundant pathways that lead to a given external state; however, this is exceedingly cumbersome to accomplish. It is, therefore, highly desirable to establish an effective computational method

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Assessment of Sustainability-Potential:  Hierarchical Approach

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Research paper thumbnail of Reduced super-structure for a separation network comprising separators effected by different methods of separation

ABSTRACT Among separation systems, the ones comprising separators effected by different separatio... more ABSTRACT Among separation systems, the ones comprising separators effected by different separation methods have been steadily gaining attention lately. Our earlier work has revealed that it is exceedingly complicated to optimally synthesize via super-structure any of these separation networks featuring simple and sharp separators, multiple feed and product streams, and mixed products. This complication can be substantially lessened by constituting a reduced super-structure for the network of interest. This super-structure profoundly simplifies the mathematical model and decreases the computational time required to yield the results identical to those obtained from the original super-structure.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Project no.: 262205 Project full title: Intensified Heat Transfer Technologies for Enhanced Heat Recovery Project Acronym: INTHEAT Deliverable no.: D6. 2 Title of the deliverable: Report on the performed marketing activities and commercialisation

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Research paper thumbnail of In-Depth Study and Comparison of S-Graph Framework and Precedence Based MILP Formulations for Batch Process Scheduling

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Research paper thumbnail of Applications of P-Graphs for Enhancing Sustainability of Industrial Plants

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Research paper thumbnail of Use the P-graph Framework to Design Supply Chains for Sustainability

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Research paper thumbnail of Risk reduction through waste minimizing process synthesis

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Research paper thumbnail of On the reformulation of some classes of PNS-problems as set covering problems.(Working paper of the Laboratory of Operations Research and Decision Systems,(LORDS) WP 97-1.)

ABSTRACT Process network synthesis (PNS) has enormous practical impact; however, its solution is ... more ABSTRACT Process network synthesis (PNS) has enormous practical impact; however, its solution is difficult in general. This experience has been recently reasoned by Blázsik and Imreh who pointed out that PNS-problems are NP-hard. They proved that a simple subclass of PNS-problems is equivalent to the class of set covering problems. In the present paper, it is shown that more general classes of PNS-problems can also be reformulated as set covering problems. This enables the sophisticated techniques developed for solving set covering problems also to be applied for solving some PNS-problems.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Part special issue-PRES'99 (2nd Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction)

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Using S-graph to adress uncertaintly in batch plants

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Current Opinion in Chemical Engineering

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Research paper thumbnail of Design of nonconventional processes Editorial overview

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Research paper thumbnail of Scheduling of Automated Wet-Etch Stations

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Research paper thumbnail of Editorial overview: Process systems engineering: Design for sustainability

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Building-evacuation-route planning via time-expanded process-network synthesis

ABSTRACT A method and software are proposed for optimal building-evacuation-route planning in ter... more ABSTRACT A method and software are proposed for optimal building-evacuation-route planning in terms of identifying evacuation routes and scheduling of evacuees on each route. First, the building-evacuation routes are represented by a P-graph, which gives rise to a time-expanded process-network synthesis ( ) problem that can be algorithmically solved by the P-graph framework. In the proposed method, each location and passage in the building is given by a set of attributes to be taken into account in the evacuation-route planning. The evacuation time is calculated as a minimum cost of the corresponding . In addition to the globally optimal solution, the P-graph framework provides the n-best sub-optimal solutions. The validity of the proposed method is illustrated by two examples.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Designing Sustainable Energy Supply Chains by the P-graph Method for Minimal Cost, Environmental Burden, Energy Resources Input

Bookmarks Related papers MentionsView impact

Research paper thumbnail of PRES conferences: Energy efficiency and environmental protection

... Heriberto Cabezas David Kukulka Martin Sponar Antonio Espuna Thoko Majozi Krzysztof Urbaniec ... more ... Heriberto Cabezas David Kukulka Martin Sponar Antonio Espuna Thoko Majozi Krzysztof Urbaniec Michalis Georgiadis Francois Marechal Spyros Voutetakis Andrzej Go´rak Josua P Meyer G+unter Wozny Kentaro Hirata Simira Papadopoulou Dominic Foo Chwan Yee ...

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Research paper thumbnail of Combinatorially accelerated branch-and-bound method for solving the MIP model of process network synthesis

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Workshop for Process Integration and Intensification, Process Optimisation and Regional Sustainability

Bookmarks Related papers MentionsView impact

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