Festus Idomeh - Academia.edu (original) (raw)

Papers by Festus Idomeh

Annals of Biomedical Sciences, Jul 31, 2019

Background: Halting the rising burden of prostate cancer across the globe has become a major publ... more Background: Halting the rising burden of prostate cancer across the globe has become a major public health challenge with the absence of intellectual consensus on the effective strategies for its prevention. However, knowledge of the disease and uptake of prostate cancer screening remain indispensable in mitigating the dire consequences of the prevalent late presentation of patients with the disease in sub-Saharan Africa. Aims and Objectives: This study was designed with an aim to assess prostate cancer knowledge and screening practices among men in Sokoto, Nigeria. Materials and Methods: A descriptive cross-sectional study was conducted among 300 participants (selected by systematic sampling technique) attending the medical and surgical outpatient clinics of UDUTH, Sokoto, Nigeria. Data were collected with a pretested, structured questionnaire and analyzed using IBM SPSS version 20 computer software.Results: The mean age of the respondents was 53.13 ± 7.92 years. Only 15 (5.0%) and 4 (1.3%) of the 300 respondents were aware of prostate cancer and prostate cancer screening respectively. Most of the respondents (95.0%) had poor knowledge of prostate cancer, and none of them have ever had a prostate cancer screening test done, with the most commonly cited reason being lack of awareness (98.6%). Conclusion: This study showed poor knowledge of prostate cancer and zero uptake of prostate cancer screening among the participants. These findings highlight the need for government and healthcare providers to sensitize the public on prostate cancer and its prevention, in addition to facilitating unrestricted access of those at risk to prostate cancer screening services.

Bulletin of Faculty of Physical Therapy

Background Exercise is beneficial to bone health. However, little is known about the interaction ... more Background Exercise is beneficial to bone health. However, little is known about the interaction effect of gender and sport type on bone turnover in young athletes. This study aimed to examine the influence of gender and sports categories (high, medium, and low impact) on bone turnover: reabsorption markers–osteocalcin, calcium, inorganic phosphate (IP), alkaline phosphatase (ALP), and resorption marker–cross-linked N-telopeptides of type 1 collagen (NTx) among a university’s undergraduate athletes. Methods The study was an ex-post facto design involving forty-seven purposively recruited gender- and sport-type-matched undergraduate athletes whose demographic characteristics and BMI were obtained. Participants’ 5 mL antecubital blood samples were collected and analysed for serum levels of osteocalcin, calcium, IP, ALP, and NTx using standard laboratory protocols, Bio-Tek spectrometer, and KC4 (3.3) software. Data were analysed using descriptive statistics and two-way ANOVA. Results T...

The 2019 Coronavirus pandemic which was initially referred to as 2019-nCoV, was first identified ... more The 2019 Coronavirus pandemic which was initially referred to as 2019-nCoV, was first identified in Wuhan, China. Early response from the Chinese government included quarantine of infected persons, isolation and total lockdown of Wuhan province to prevent further spread. With the spread of the disease across national borders and declaration of the disease as a global pandemic, there has been a robust response by the international community to contain this deadly virus and prevent its further spread worldwide. Africa is not left out of this rampaging pandemic with documented cases in over 40 countries and still rising. Although extensive studies have been carried out on the novel SARS-CoV-2 on its pathogenesis, mode of infection and virulence but much is still unknown. However, potentially infectious samples are received routinely in the medical laboratory for analysis. This technical note reviews good laboratory practice (GLP) and processes across the different specialities of Medic...

Annals of Biomedical Sciences, 2019

This study was to ascertain the absolute neutrophil and lymphocyte count and functions in male su... more This study was to ascertain the absolute neutrophil and lymphocyte count and functions in male subjects with prostate cancer. Subjects with clinical evidence of prostate cancer were recruited for this study and classified based on drug administration for 12 weeks (subjects on drug therapy and those not on drug therapies). Neutrophil function using Nitroblue Tetrazolium dye reduction, Lymphocyte transformation (%) using mitogens (concanavalin A and phytohaemagglutinin (PHA), CD4+ count (cells/μl) using cyflow counter, Total white blood cell count (x 109/L), Absolute lymphocyte count (x 109/L), and Absolute neutrophil count (x 109/L) were used as markers of immune function. Neutrophil function, percentage lymphocyte transformation using phytohaemagglutinin and concanavallin A in prostate cancer subjects were significantly lower (P=0.000) when compared with values obtained from the control group. They were also significantly lower (P=0.000) in prostate cancer subjects on drug therapy c...

Journal of Applied Sciences and Environmental Management, 2021

Exposure to e-waste either by occupation or through the environment have been implicated in cance... more Exposure to e-waste either by occupation or through the environment have been implicated in cancer development. The growing influx of e-waste to Nigeria and inadequate recycling, part salvaging, distribution and disposal of discarded or obsolete electronic devices is creating new sets of environmental and public health challenges. This study investigated the effect of exposure on vitamin D (25(OH) Vit D), total and ionized calcium levels in workers and individuals environmentally exposed to e-waste in Lagos, Benin and Ibadan cities in Southwestern Nigeria. Six hundred and thirty-two participants from three major cities in Nigeria were recruited for this study. They included e-waste workers, environmental e-waste exposed individuals and age matched unexposed individuals. 25(OH) Vit D was determined using ELISA, while total and ionized calcium by colorimetric method. Total calcium (tCa) in e-waste workers was significantly different from environmental exposed groups (p=0.000) while io...

Asian Journal of Medical Sciences, 2018

Nigerian Journal of Basic and Applied Sciences, 2017

This study aimed to investigate the short-term effects of Highly Active Antiretroviral Therapy (H... more This study aimed to investigate the short-term effects of Highly Active Antiretroviral Therapy (HAART) (stavudine, lamivudine and nevirapine) on serum lipids of HIV-1 positive subjects in Benin City, Nigeria. Test group 1 (n=78) and test group 2 (n= 71) comprised HIV-1 seropositive individuals on HAART for a period of one to three months; and five to six months respectively. Fifty five newly diagnosed HIV-1 positive subjects naïve to HAART served as control group 1 and sixty apparently healthy HIV-1 seronegative individuals served as control group 2. The blood samples obtained were analyzed for total cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein using standard enzymatic methods. Total cholesterol of test group 2 (214.0±6.43mg/dL) was not significantly different from Test group 1 (202.4±5.09mg/dL), both were however significantly higher than control group 1 (159.3±5.09mg/dL) and control group 2 (101.6±3.76 mg/dL). Triglyceride concentration of test group 2 (106.6+11.95mg/dL) was not significantly different from test group 1 (135.8+9.88mg/dL), but were significantly different from control groups 1 and 2 (125.1+3.35mg/dL and 104.6+3.08mg/dL) respectively. Dyslipidemia could set in from 1 to 6 months of HAART usage in HIV-1 Positive subjects hence serum lipids should be monitored as early as one month of HAART commencement.

Background: The volume of electronic waste (e-waste) received in Nigeria is reportedly on the inc... more Background: The volume of electronic waste (e-waste) received in Nigeria is reportedly on the increase and the effects on environmental health are yet to be fully ascertained. This study aimed to investigate possible variation of haematological indices, lead and serum iron levels in workers occupationally exposed to electronic wastes in Benin City, South-South, Nigeria. Methods: In this pilot study, 104 participants were enrolled from Benin City, South-South Nigeria; consisting of 63 E-waste Workers (EW) sex-and aged-matched with 41 Unexposed Participants (Control). Blood samples were collected and analysed for levels of the metals (lead and iron) using Inductively Coupled Plasma-Mass Spectrometry while the haematological parameters [White Blood Cells (WBC), Lymphocytes (LY); Monocytes (MO), Granulocytes (GR), Red Blood Cells (RBC), Haemoglobin (Hgb), Haematocrit (HCT), Mean Cell Volume (MCV), Mean Cell Haemoglobin (MCH), Mean Cell Haemoglobin Concentration (MCHC) and Platelets (PLT)] were determined using Haematology Auto-analyser. Results: Serum iron (p<0.007) was significantly lower while lead was higher (p<0.001) among EW than controls. Also, LY, PLT, Hgb, PCV and MCHC were significantly lower (p<0.001) while TWBC (p<0.001), MO (p<0.05), GR (p<0.001) and MCV were higher among EW than control subjects. Conclusion: E-waste exposure may increase blood lead level, lower serum iron status and may have adversely altered the measured haematological parameters in the studied population.

Journal of Chemical Health Risks, 2015

Large volumes of mostly irreparable electronic waste (e-waste) are shipped to Africa on a monthly... more Large volumes of mostly irreparable electronic waste (e-waste) are shipped to Africa on a monthly basis, of which Nigeria receives the largest share. E-waste management practices in Nigeria have remained completely primitive until date; and e-waste workers have little or no occupational safety knowledge and devices. The thousands of chemicals in e-waste have been reported to be toxic to human health in any degree of exposure. The present study has assessed the risk of liver damage in workers occupationally exposed to e-waste in Benin City, South-south Nigeria in 2014. Serum activities of liver enzymes (alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase (GGT) and alkaline phosphatase (ALP)); and levels albumin (ALB), total bilirubin (T/Bil) and conjugated bilirubin (C/Bil) were determined using standard colorimetric methods. Serum Alpha fetoprotein (AFP) was determined using ELISA in Nigerian e-waste workers (n=63) and in age-matched unexposed...

Geomicrobiology Journal, 2021

Abstract Petroleum pollution of coastal areas such as Nigeria’s Niger Delta is increasingly alarm... more Abstract Petroleum pollution of coastal areas such as Nigeria’s Niger Delta is increasingly alarming. After an oil spill, aquatic organisms, including indigenous microbial communities are affected, leading to an increased abundance of oil degraders in the affected environment. During the last decade, microbial ecology research has shifted from cultivation and characterization of individual environmental isolates to metagenomics studies that are focused on the characterization of community dynamics and composition. In this study, we determined the indigenous bacterial community in water bodies polluted with crude oil in Delta State, Nigeria by Next Generation Sequencing (NGS). Oil hydrocarbon composition was determined by Gas Chromatography–Mass Spectrometry analysis (GC–MS) and the physical-chemical dynamics were assessed using standard procedures. Results revealed Proteobacteria (76.9%), Bacteroidetes (8.5%) and Firmicutes (1.1%) as the dominant phyla. GC–MS data revealed different petroleum hydrocarbon concentrations across the seasons and locations sampled. The indigenous bacterial community included the prevalence of oil degrades with Methylotenera as the major genus. This study suggests that Methylotenera could be a useful agent for bioremediation in the Niger Delta.

The volume of electronic waste (e-waste) received in Nigeria is reportedly on the increase and th... more The volume of electronic waste (e-waste) received in Nigeria is reportedly on the increase and the effects on environmental health are yet to be fully ascertained. This study aimed to investigate haematological indices, lead and serum iron levels in workers occupationally exposed to electronic wastes in South-South, Nigeria. In this pilot study, 104 participants were enrolled from Benin City, South-South Nigeria; consisting of 63 E-waste Workers (EW) sex- and aged-matched with 41 Unexposed Participants (Control). Blood levels (5 mL) of the metals (lead and iron) were determined using Inductively Coupled Plasma-Mass Spectrometry while the haematological parameters [white blood cells (WBC), Lymphocytes ( LY); monocytes (MO), granulocytes(GR), red blood cells (RBC), haemoglobin (Hgb), haematocrit (HCT), mean cell volume (MCV), mean cell haemoglobin (MCH), mean cell haemoglobin concentration (MCHC) and platelets (PLT)] were determined using standard methods. Results obtained from this s...

Maedica, 2020

Aim: This study investigated the effects of e-waste occupational exposure on lipid profile and at... more Aim: This study investigated the effects of e-waste occupational exposure on lipid profile and atherogenic indices in Waste Electrical and Electronic Workers in South-South Nigeria. Matrials and methods: Whole blood levels of lead and cadmium were analyzed using ICPMS (Inductively Coupled Plasma Mass Spectrometry). Total serum cholesterol (TC), high density lipoprotein (HDL) cholesterol and triglycerides (TG) were determined using spectrophotometric method. Low density lipoprotein (LDL) cholesterol value was calculated by the Friedewald equation using analyzed values of TC, HDL cholesterol and TG. Atherogenic index of plasma (AIP) was calculated as log TG/HDLc, atherogenic coefficient (AC) as [(TC-HDLc)/HDLc], Castelli risk index (CRI-1) as (TC/HDLc) and CRI-II as (LDLc/HDLc). Results: Total cholesterol, LDL cholesterol, AC, CRI-1 and CRI-11 significantly increased in the e-waste exposed participants compared to the unexposed group. Significant positive correlations between lead and...