Filipe Jaeger - Academia.edu (original) (raw)

Papers by Filipe Jaeger

__________________________________________________________________________________________ RESUMO... more __________________________________________________________________________________________ RESUMO -A impactação/inclusão dentária é definida como o insucesso do elemento dentário em se posicionar corretamente na arcada, permanecendo parcialmente ou totalmente no interior do osso alveolar, após o período de formação radicular. Este trabalho descreve o caso de um paciente submetido à tomografia computadorizada cone-beam, por apresentar um quarto molar inferior incluso em posição transversal, que inicialmente, foi visualizado por exames radiográficos convencionais e demonstrava íntima relação com estruturas anatômicas adjacentes. Por meio deste exame, pode-se observar com precisão os limites do dente e sua relação com as estruturas anatômicas circunvizinhas. Entretanto, fica evidenciado que o emprego adequado de uma técnica convencional de localização, como por exemplo, a técnica de Donovan, pode ser de grande valia para o cirurgião-dentista no planejamento cirúrgico e garantir um diagnóstico seguro sobre tal condição.

The American journal of case reports, Jan 30, 2015

BACKGROUND Spindle cell lipoma (SCL) is an uncommon and histologically distinct variant of lipoma... more BACKGROUND Spindle cell lipoma (SCL) is an uncommon and histologically distinct variant of lipoma. It usually occurs as a solitary, subcutaneous, and well-circumscribed lesion in the posterior neck, shoulders, and back of older men. SCL of the oral cavity is rare. We present the clinical-pathologic features of the third case of SCL located on the hard palate and discuss the histological differential diagnosis with other fusiform neoplasms. CASE REPORT A 56-year-old man was evaluated for an asymptomatic swelling on the right side of the hard palate. The intraoral examination showed a 25×20 mm sessile and circumscribed tumor, underlying an apparently healthy mucosa of normal color. The lesion revealed a floating consistency during palpation. Excisional biopsy was carried out based on a clinical diagnosis of lipoma or a benign minor salivary gland tumor. The histopathology demonstrated a well-circumscribed but unencapsulated proliferation of bland spindle cells admixed with mature adip...

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2013

informação sobre o artigo Historial do artigo: Recebido a 25 de novembro de 2012 Aceite a 23 de j... more informação sobre o artigo Historial do artigo: Recebido a 25 de novembro de 2012 Aceite a 23 de janeiro de 2013 On-line a xxx Palavras-chave: Terapia esclerosante Hemangioma Oleato de etanolamina r e s u m o Alteraç ões vasculares benignas são descritas como anomalias de desenvolvimento dos vasos sanguíneos de etiologia desconhecida. Fazem parte deste grupo as malformaç ões vasculares, os hemangiomas, os linfangiomas e as varicosidades. Normalmente são assintomáticos, porém, o crescimento progressivo da lesão pode facilitar injúrias traumáticas locais, causando dor, ulceraç ões e sangramentos inesperados. A excisão cirúrgica convencional, eletrocauterização, laserterapia, embolização, crioterapia e escleroterapia química são opç ões terapêuticas para o tratamento dos hemangiomas orais. O objetivo deste artigo é apresentar um caso clínico de hemangioma oral, onde o tratamento de escolha foi a esclerose com oleato de etanolamina 5%. O paciente permanece estável após 2 anos da escleroterapia. Hemangioma Ethanolamine oleate a b s t r a c t Benign vascular changes are described as anomalies of blood vessel's development of unknown etiology. Included in this group are vascular malformations, hemangiomas, lymphangiomas and varicositie. Despite usually asymptomatic, the progressive growth of these lesions may lead to local traumatic injuries, causing pain, ulceration and unexpected

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2013

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2015

The aim of this study was to compare the salivary epidermal growth factor (EGF) levels between pa... more The aim of this study was to compare the salivary epidermal growth factor (EGF) levels between patients with oral leukoplakia (OL) and clinically healthy individuals, to evaluate the association between salivary and tissular EGF, and to correlate EGF with clinicopathologic data, including the presence of dysplasia. Salivary EGF levels were measured in 32 patients and 32 controls. The tissue expressions of EGF and its receptor (EGFR) were immunohistochemically evaluated. Salivary EGF levels were similar in patients with OL compared with controls. There was no association between the salivary levels and immunohistochemical expression of EGF. An absence of EGF detection by immunohistochemistry was associated with development of multiple lesions. Dysplastic lesions showed a tendency toward presenting higher salivary EGF levels. Currently, it is not possible to indicate salivary EGF as a biomarker for OL. Further studies are needed to elucidate the role of EGF in oral carcinogenesis. A follow-up study is necessary to evaluate the changes in EGF values following the surgical excision of OL.

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2012

informação sobre o artigo Historial do artigo: Recebido a 17 de março de 2012 Aceite a 25 de junh... more informação sobre o artigo Historial do artigo: Recebido a 17 de março de 2012 Aceite a 25 de junho de 2012 Palavras-chave: Tumores odontogênicos Odontoma Hamartoma r e s u m o Os odontomas constituem-se como os tumores odontogénicos mais comuns, sendo definidos como uma malformação benigna, em que as células alcançam completa diferenciação, atingindo o estágio, no qual todos os tecidos dentais estão representados. São classificados em odontomas complexos e compostos. Normalmente, são assintomáticos e diagnosticados através de exames radiográficos de rotina. O tratamento para este tipo de lesão é a exérese cirúrgica e o prognóstico é excelente. O objetivo deste trabalho é realizar uma revisão da literatura sobre o assunto e apresentar um caso de odontoma composto de uma paciente de 26 anos do género feminino atendida na clínica de Estomatologia da Faculdade de Odontologia da PUC Minas. a b s t r a c t Odontomas consists as the more common odontogenic tumors, being defined as a benign malformation, in which the cells attain complete differentiation, reaching the stage in which all dental tissues are represented. They are classified complex and compound odontomas. They are usually asymptomatic and diagnosed by routine radiographic examination. The treatment for this type of lesion is surgical excision and the prognosis is excellent. This paper aim is to review literature on the subject and present a case of compound odontoma in a 26 years female patient treated in the Stomatology clinic of the School of Dentistry at PUC Minas. r e v p o r t e s t o m a t o l m e d d e n t c i r m a x i l o f a c . 2 0 1 2;5 3(4):252-257

Revista Portuguesa de Estomatología, Medicina Dentária e Cirugia Maxilofacial, 2011

Oral and Maxillofacial Surgery, 2010

Purpose The surgical treatment of a large complex odontoma in the mandibular angle is reported. F... more Purpose The surgical treatment of a large complex odontoma in the mandibular angle is reported. Four possible surgical approaches to remove a benign tumor in the mandibular angle are discussed. Patient A two-stage surgical treatment was chosen; first, removing most part of the lesion and preserving the second molar, decreasing the risk of a pathological mandibular fracture. A maxillo-mandibular fixation for a period of 4 weeks was used. The patient was oriented to maintain a soft diet. The second surgical stage occurred 3 months after the first one due to the significant bone consolidation observed, reducing the possibility of a mandibular fracture. The remaining lesion and the second molar were then completely removed. Conclusions This case demonstrates the value of the tridimensional computed tomography in treatment planning prior to any definitive surgery. A computed tomography should be made in every case of intraosseous lesion in order to establish the intraosseous extent of the tumor, cortical perforation, and soft tissue involvement for precise guidance for the surgical planning. It is recommended that the surgeon considers excision by an intraoral, lingual approach when indicated, and in two stages, when an extremely thin mandibular base is present.

Revista Española de Cirugía Oral y Maxilofacial, 2013

información del artículo Historia del artículo: Recibido el 23 de enero de 2013 Aceptado el 24 de... more información del artículo Historia del artículo: Recibido el 23 de enero de 2013 Aceptado el 24 de marzo de 2013 On-line el xxx Palabras clave: Ameloblastoma Tumor odontogénico Epidemiología r e s u m e n

Human Immunology, 2015

The goal of this study was to compare the salivary concentrations of IL-10, TGF-b1 and soluble HL... more The goal of this study was to compare the salivary concentrations of IL-10, TGF-b1 and soluble HLA-G (sHLA-G) in patients with oral squamous cell carcinoma (OSCC) to those in healthy individuals (control group), and to correlate the expression of these mediators in saliva with that in the tumour microenvironment. Neoplastic tissue and saliva samples from patients with OSCC (n = 22) were analysed by immunohistochemistry and enzyme-linked immunosorbent assay (ELISA) respectively. We detected high expression of IL-10 and HLA-G in the tumour microenvironment when compared to healthy oral mucosa samples. Determination of IL-10 salivary concentration enabled us to distinguish patients with OSCC from healthy individuals (P = 0.038), which showed correlation with tissue expression of this cytokine. HLA-G salivary release was similar in both groups (P = 0.17) and no correlation with tumour expression was observed. TGF-b1 expression was low or absent in tumours, and salivary concentration was similar between groups. Our results suggest that of the three markers analysed, IL-10 is a potential salivary biomarker. Furthermore, the elevated expression of HLA-G and IL-10 in tumour sites could favour the escape of tumour cells from immune defense mechanisms. Ó

The American journal of case reports, Jan 30, 2015

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2013

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2015

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2012

Revista Portuguesa de Estomatología, Medicina Dentária e Cirugia Maxilofacial, 2011

Oral and Maxillofacial Surgery, 2010

Revista Española de Cirugía Oral y Maxilofacial, 2013

Human Immunology, 2015