Francisco Juan Martínez Rojas - Academia.edu (original) (raw)
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Papers by Francisco Juan Martínez Rojas
Literatura Teoria Historia Critica, Jan 20, 2010
Çalışmanın amacı, yeni iletişim teknolojilerinin kamu diplomasisine olan etkilerini "dijital dipl... more Çalışmanın amacı, yeni iletişim teknolojilerinin kamu diplomasisine olan etkilerini "dijital diplomasi" kavramsal çerçevesinde ve örnek sosyal medya faaliyetleri vasıtasıyla ortaya koymaktır. Yöntem: Bu amaçla, örnek olay olarak belirlenen Birleşik Krallık ve Finlandiya Ankara Büyükelçilik Facebook hesaplarından Mayıs 2018-Ekim 2018 tarihleri arasında yapılan paylaşımlar ve etkileşimler (yorum, beğeni, yeniden paylaşım) içerik analizi metodu yardımıyla incelenmiştir. Finlandiya ve Birleşik Krallık hesapları ürettikleri içerik ve sosyal medya stratejileri çerçevesinde ayrı ayrı değerlendirildikten sonra sosyal medyanın proaktif kullanımı, kullanılan multimedya araçları ve etkileşime açıklık bağlamında aralarında bir karşılaştırma da yapılmıştır. Bulgular: Çalışma ile dijital diplomasi bağlamındaki proaktif sosyal medya kullanımının (paylaşımların reklamlarla öne çıkarılması, sosyal medya fenomenlerinden faydalanma, etkileşimsel sosyal medya özelliklerini kullanma vb.) kullanıcılarla olan etkileşimi arttırarak ülkelerin öne çıkardıkları yönlerinin ve politikalarının daha geniş bir kitleye yayılmasını sağladığı sonucuna varılmıştır. Ayrıca örnek vakadaki diplomatik sosyal medya hesaplarının strateji ve paylaşımlarının o ülkelerin dış politika hedefleriyle uyumlu olduğu görülmüştür.
Background. Antenatal exposure to parasites can affect infants' subsequent responses to vaccinati... more Background. Antenatal exposure to parasites can affect infants' subsequent responses to vaccination. The present study investigated how maternal prenatal infections and newborns' antiparasite cytokine profiles relate to immunoglobulin G (IgG) responses to standard vaccination during infancy. Methods. A total of 450 Kenyan women were tested for parasitic infections during pregnancy. Their newborns' responses to Plasmodium falciparum, schistosome, and filaria antigens were assessed in cord blood lymphocytes. Following standard neonatal vaccination, this infant cohort was followed biannually to age 30 months for measurement of circulating IgG levels against Haemophilus influenzae b (Hib), diphtheria toxoid (DT), hepatitis B virus (HBV), and tetanus toxoid. Results. Trajectories of postvaccination IgG levels were classified by functional principal component (PC) analysis to assess each child's response profile. Two main components, PC1, reflecting height of response over time, and PC2, reflecting crossover from high to low responses or from low to high responses, were identified. Cord blood cytokine responses to schistosome and filarial antigens showed a significant association between augmented antihelminth interleukin 10 and reduced antibody levels, particularly to DT and HBV, and a more rapid postvaccination decline in circulating IgG levels against Hib. Conclusion. Antenatal sensitization to schistosomiasis or filariasis and related production of antiparasite interleukin 10 at birth are associated with reduced antivaccine IgG levels in infancy, with possibly impaired protection.
Objectives-To determine the extent to which initial therapy for nonmetastatic prostate cancer was... more Objectives-To determine the extent to which initial therapy for nonmetastatic prostate cancer was concordant with nationally recognized guidelines using supplemented cancer registry data and what factors were associated with receipt of nonguideline-concordant care. Methods-Initial therapy for 8229 nonmetastatic prostate cancer cases diagnosed in 2004 from cancer registries in 7 states was abstracted as part of the Centers for Disease Control's Patterns of Care Breast and Prostate Cancer study conducted during 2007 to 2009. The National Comprehensive Cancer Network clinical practice guidelines version 1.2002 was used as the standard of care based on recurrence risk group and life expectancy (LE). A multivariable model was used to determine risk factors associated with receipt of nonguideline-concordant care. Results-Nearly 80% with nonmetastatic prostate cancer received guideline-concordant care for initial therapy. Receipt of nonguideline-concordant care (including receiving either less aggressive therapy or more aggressive therapy than indicated) was related to older age, African American race/ethnicity, being unmarried, rural residence, and especially to being in the high recurrence risk
Literatura Teoria Historia Critica, Jan 20, 2010
Çalışmanın amacı, yeni iletişim teknolojilerinin kamu diplomasisine olan etkilerini "dijital dipl... more Çalışmanın amacı, yeni iletişim teknolojilerinin kamu diplomasisine olan etkilerini "dijital diplomasi" kavramsal çerçevesinde ve örnek sosyal medya faaliyetleri vasıtasıyla ortaya koymaktır. Yöntem: Bu amaçla, örnek olay olarak belirlenen Birleşik Krallık ve Finlandiya Ankara Büyükelçilik Facebook hesaplarından Mayıs 2018-Ekim 2018 tarihleri arasında yapılan paylaşımlar ve etkileşimler (yorum, beğeni, yeniden paylaşım) içerik analizi metodu yardımıyla incelenmiştir. Finlandiya ve Birleşik Krallık hesapları ürettikleri içerik ve sosyal medya stratejileri çerçevesinde ayrı ayrı değerlendirildikten sonra sosyal medyanın proaktif kullanımı, kullanılan multimedya araçları ve etkileşime açıklık bağlamında aralarında bir karşılaştırma da yapılmıştır. Bulgular: Çalışma ile dijital diplomasi bağlamındaki proaktif sosyal medya kullanımının (paylaşımların reklamlarla öne çıkarılması, sosyal medya fenomenlerinden faydalanma, etkileşimsel sosyal medya özelliklerini kullanma vb.) kullanıcılarla olan etkileşimi arttırarak ülkelerin öne çıkardıkları yönlerinin ve politikalarının daha geniş bir kitleye yayılmasını sağladığı sonucuna varılmıştır. Ayrıca örnek vakadaki diplomatik sosyal medya hesaplarının strateji ve paylaşımlarının o ülkelerin dış politika hedefleriyle uyumlu olduğu görülmüştür.
Background. Antenatal exposure to parasites can affect infants' subsequent responses to vaccinati... more Background. Antenatal exposure to parasites can affect infants' subsequent responses to vaccination. The present study investigated how maternal prenatal infections and newborns' antiparasite cytokine profiles relate to immunoglobulin G (IgG) responses to standard vaccination during infancy. Methods. A total of 450 Kenyan women were tested for parasitic infections during pregnancy. Their newborns' responses to Plasmodium falciparum, schistosome, and filaria antigens were assessed in cord blood lymphocytes. Following standard neonatal vaccination, this infant cohort was followed biannually to age 30 months for measurement of circulating IgG levels against Haemophilus influenzae b (Hib), diphtheria toxoid (DT), hepatitis B virus (HBV), and tetanus toxoid. Results. Trajectories of postvaccination IgG levels were classified by functional principal component (PC) analysis to assess each child's response profile. Two main components, PC1, reflecting height of response over time, and PC2, reflecting crossover from high to low responses or from low to high responses, were identified. Cord blood cytokine responses to schistosome and filarial antigens showed a significant association between augmented antihelminth interleukin 10 and reduced antibody levels, particularly to DT and HBV, and a more rapid postvaccination decline in circulating IgG levels against Hib. Conclusion. Antenatal sensitization to schistosomiasis or filariasis and related production of antiparasite interleukin 10 at birth are associated with reduced antivaccine IgG levels in infancy, with possibly impaired protection.
Objectives-To determine the extent to which initial therapy for nonmetastatic prostate cancer was... more Objectives-To determine the extent to which initial therapy for nonmetastatic prostate cancer was concordant with nationally recognized guidelines using supplemented cancer registry data and what factors were associated with receipt of nonguideline-concordant care. Methods-Initial therapy for 8229 nonmetastatic prostate cancer cases diagnosed in 2004 from cancer registries in 7 states was abstracted as part of the Centers for Disease Control's Patterns of Care Breast and Prostate Cancer study conducted during 2007 to 2009. The National Comprehensive Cancer Network clinical practice guidelines version 1.2002 was used as the standard of care based on recurrence risk group and life expectancy (LE). A multivariable model was used to determine risk factors associated with receipt of nonguideline-concordant care. Results-Nearly 80% with nonmetastatic prostate cancer received guideline-concordant care for initial therapy. Receipt of nonguideline-concordant care (including receiving either less aggressive therapy or more aggressive therapy than indicated) was related to older age, African American race/ethnicity, being unmarried, rural residence, and especially to being in the high recurrence risk