Fred Cahn - Academia.edu (original) (raw)

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Papers by Fred Cahn

ICASSP '83. IEEE International Conference on Acoustics, Speech, and Signal Processing

In an attempt to design trumpet timbres for digital music synthesis, notes of a trumpet were digi... more In an attempt to design trumpet timbres for digital music synthesis, notes of a trumpet were digitally recorded. Spectral analysis at high resolution showed both a harmonic line spectrum and a weak continuous spectrum. The continuous spectrum did not appear to contribute to the tone. Shifting the pitch by sample rate conversion (interpolation or decimation) caused serious changes in tone unless the spectral envelope was deconvolved from the signal before pitch shifting and reconvolved with the shifted signal. This procedure can be used to simulate the spectral envelope of a trumpet, which remains roughly constant as the pitch is changed.

Surgical endoscopy, Dec 23, 2017

The endoscopic radiofrequency procedure (Stretta) has been used for more than a decade to treat p... more The endoscopic radiofrequency procedure (Stretta) has been used for more than a decade to treat patients with gastroesophageal reflux disease (GERD). However, the efficacy of the procedure in improving objective and subjective clinical endpoints needs to be further established. To determine the efficacy of the Stretta procedure in treating patients with GERD, using a systematic review and meta-analysis of controlled and cohort studies. We conducted a systematic search of the PubMed and Cochrane databases for English language clinical studies of the Stretta procedure, published from inception until May 2016. Randomized controlled trials (RCTs) and cohort studies that included the use of the Stretta procedure in GERD patients were included. A generalized inverse weighting was used for all outcomes. Results were calculated by both fixed effects and random effects model. Twenty-eight studies (4 RCTs, 23 cohort studies, and 1 registry) representing 2468 unique Stretta patients were inclu...

7th Intl Conf on Fourier Transform Spectroscopy, 1989

ABSTRACT A series of spectra have been recorded during a varying evolution of gases from a thermo... more ABSTRACT A series of spectra have been recorded during a varying evolution of gases from a thermogravimetric analyzer. The composition of the gas mixture has been analyzed by target factor transformation, in order to test whether this procedure will be able to identify the components without operator intervention. The major components evolved during the weight loss were identified, which demonstrates that this approach is valid.

Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology, 1991

Spherical porous microcarriers (PMCs) made from collagen-glycosaminoglycan crosslinked copolymers... more Spherical porous microcarriers (PMCs) made from collagen-glycosaminoglycan crosslinked copolymers have exhibited considerable promise as growth surfaces for the proliferation of anchorage-dependent mammalian cell lines and have demonstrated the ability to entrap anchorage-independent cells. However, quantification of cell growth on PMCs has proved difficult. A method of measuring the proliferation of PMCs, based on image analysis, is presented. Using CV1 and CHO cell lines, samples of PMCs were removed from culture at various times, fixed, embedded and sectioned. The 2 microns sections were stained, photographed and digitized in three colors. A computer program was developed to evaluate digitized PMC cross-sections and to classify pixels as conforming to either background, cytoplasmic, matrix or nuclear parameters, based on a set of classification rules determined by statistical analysis. Growth curves were generated by relating the number of pixels occupied by cellular material to ...

The Journal of biological chemistry, Jan 10, 1978

We treated intact reticulocytes with nystatin to make them permeable to small cations and varied ... more We treated intact reticulocytes with nystatin to make them permeable to small cations and varied the concentration of K+ in the medium; the ionic strength was kept constant by adjusting Na+. As the intracellular K+ was lowered, the rate of protein synthesis decreased. In a reticulocyte lysate, the dependence of the rate of protein synthesis on K+ concentration (at constant ionic strength) was similar to that seen in nystatin-treated cells. We observed no loss of polysomes at low K+. Even when initiation was blocked with aurintricarboxylic acid, decreased K+ inhibited protein synthesis. Analysis of the kinetics of synthesis showed that lowering the K+ concentration inhibits the rate of elongation of nascent chains, but has little effect on the relative rate of initiation of chains.