Ahmet Güzel - Academia.edu (original) (raw)
Papers by Ahmet Güzel
ocukta dermatolojik aciller: 5 yıllık deneyim
... Olguların 4'ü (%0.8) yenidoğan, 70'i (%14.1) süt çocuğu, 161'i (%3... more ... Olguların 4'ü (%0.8) yenidoğan, 70'i (%14.1) süt çocuğu, 161'i (%32.3) oyun çocuğu ve 263'ü (%52.8) ise okul çocuğu idi ... Dermatological emergencies in childhood: 5 years experience AhmetGüzel 1 , Serap Karasalihoğlu 1 , Esra Hazar Sayar 1 , Özer Arıcan 2 , Cemil Kavalcı 3 ...
Emergency Peripartum Hysterectomy: 16-year Experience of a Medical Hospital
Journal of The Chinese Medical Association, 2010
We conducted this retrospective study to evaluate the outcomes and indications of emergency perip... more We conducted this retrospective study to evaluate the outcomes and indications of emergency peripartum hysterectomy (EPH) as a life-saving procedure. We analyzed a series of 140 cases of EPH, between January 1993 and December 2008 in our clinic, retrospectively. The data were collected from the patients' files. The incidence, demographic characteristics, risk factors, indications and outcomes of hysterectomy, peripartum complications, the operation types, maternal morbidity and mortality and fetal mortality were evaluated. A total of 26,015 of women were delivered. The incidence of EPH was 5.38 per 1,000 deliveries. The mean age was 34.19 +/- 6.04 years (range, 21-49 years), gravidity was 6.84 +/- 3.38 (1-17) and parity was 5.58 +/- 3.04 (0-15). Of the 140 cases, 90 were delivered by cesarean section [29 (20.71%) of these had had a previous cesarean section] and 50 were vaginally delivered. One hundred and five cases had subtotal hysterectomy and 35 had total abdominal hysterectomy. The most common indications for EPH were uterine atony followed by uterine rupture and abnormal placentation. Mean operation time was 142.23 +/- 43.70 minutes. The average blood transfusion was 4.79 +/- 3.36 (1-14) units. Relaparotomy was performed in 23 cases. Maternal mortality was seen in 13 cases. Seventy-nine of the cases delivered at an outside center and were referred to our clinic for the intensive care unit. Sixty-one of the cases delivered at our clinic and 31 had stillbirths. This study suggests that the most common indications for EPH are uterine atony, uterine rupture and abnormal placentation. This is probably due to the advanced age of pregnancies and multiparity in our region. Therefore, we believe that the risk of EPH may be decreased with appropriate and closer prenatal care as well as education of the pregnant women.
Taiwanese Journal of Obstetrics & Gynecology, 2011
Placental site trophoblastic tumors (PSTTs) are an extremely rare form of gestational trophoblast... more Placental site trophoblastic tumors (PSTTs) are an extremely rare form of gestational trophoblastic disease (GTD). Marchand and Ewing made the first observations in 1895 and 1910, respectively, and Kurman and Scully described the clinical and pathological characteristics of PSTTs in 1976, when the term trophoblastic pseudotumor was adopted to characterize the apparently benign nature of the disease [1,2]. Subsequent case reports have presented evidence of a sometimes aggressive, malignant, and fatal course of the disease, and the name was changed to PSTT in 1981 [3]. Histopathologically, PSTTs are characterized by a neoplastic monomorphic population of implantation-like intermediate trophoblastic cells, often as sheets of polyhedral, rounded, or occasionally spindle-shaped cells that infiltrate the myometrium extensively. Because of the rarity of this type of tumor, there is little information about its epidemiology and etiology, and few large series on diagnosis and treatment have been published . PSTTs are most often seen in patients of reproductive age and can follow a normal pregnancy, miscarriage, or GTD. Irregular vaginal bleeding is the most common presenting feature, although a wide range of other symptoms has also been reported, including galactorrhea, virilization, nephrotic syndrome, and polycythemia . We report two cases of PSTT treated successfully in our clinic.
Scalp Dermatophyte Carriage in Pregnant, Pre, and Postmenopausal Women: A Comparative Study Using the Hairbrush and Cytobrush Methods of Sample Collection
Mycopathologia, 2011
Tinea capitis is a dermatophyte infection of the scalp that is most often seen in prepubescent ch... more Tinea capitis is a dermatophyte infection of the scalp that is most often seen in prepubescent children. In this investigation, we examined the prevalence of tinea capitis and symptom-free colonization of the scalp with dermatophytes in 786 pre- and postmenopausal women aged 12–84 years. Scalp samples were collected from all participants by cytobrush or hairbrush, and cultures were then grown from these samples on Sabouraud glucose agar. No participant was diagnosed with tinea capitis; however, one 43-year-old patient (0.1%) was positive for a “scalp carriage” related to anthropophilic Trichophyton rubrum, as detected using a hairbrush. The internal transcribed spacer (ITS) regions of the isolate were sequenced, and the assembled DNA sequences were examined using the basic BLAST (nucleotide–nucleotide) software of the National Center for Biotechnology Information Web database. This patient was followed up without any antimycotic treatment, and after 4 weeks, mycological clearance was documented. In addition, the contacts and environment at home were screened, where all fungal cultures were sterile. To the best of our knowledge, this study is the first report of a “scalp carriage” related to a cosmopolitan fungus, T. rubrum.
BACKGROUND: It is reported that prevalence of overweight and obesity have increased in all age gr... more BACKGROUND: It is reported that prevalence of overweight and obesity have increased in all age groups, but little is known about prevalence of overweight and obesity in preschool children. Therefore, the purpose of this study was to survey the prevalence of underweight, overweight and obesity in 3-6 year-old Tehranian children in 2009-2010.
Biner B, Çeltik C, Öner N, Küçükuğurluoğlu Y, Güzel A, Yıldırım Ç, Adalı MK. The comparison of si... more Biner B, Çeltik C, Öner N, Küçükuğurluoğlu Y, Güzel A, Yıldırım Ç, Adalı MK. The comparison of single-dose ceftriaxone, five-day azithromycin, and ten-day amoxicillin/clavulanate for the treatment of children with acute otitis media. Turk J Pediatr 2007; 49: 390-396. The aim of the study was to evaluate the efficacy of short-course antimicrobial therapies [single intramuscular dose of ceftriaxone (50 mg/kg, not exceeding 1 g), 5 days of azithromycin (10 mg/kg on day 1, then 5 mg/kg daily on days 2-5) and the traditional 10-day course of amoxicillin/clavulanate (90/6.4 mg/kg/day in 2 doses)] in children with acute otitis media (AOM). The study was conducted as a prospective, comparative, open randomized trial between February 2001 and April 2003, and 104 children were enrolled, with a mean age of 3.8 (2.3) years.
Ceftriaxone-associated biliary pseudolithiasis in children
Journal of Clinical Ultrasound, 2006
Purpose.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in th... more Purpose.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in the gallbladder and urinary tract. The aim of this study was to investigate the incidence and predisposing factors that contribute to this side effect.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in the gallbladder and urinary tract. The aim of this study was to investigate the incidence and predisposing factors that contribute to this side effect.Methods.A prospective study was conducted in 156 children admitted for the treatment of various infections with different daily ceftriaxone doses (50 mg/kg, 75 mg/kg, and 100 mg/kg). Sonographic examinations of the gallbladder and urinary tract were performed before treatment on the third and seventh day of therapy, and at the first and second month after the end of treatment. Patients with positive findings were followed with weekly sonographic examinations until the abnormality resolved.A prospective study was conducted in 156 children admitted for the treatment of various infections with different daily ceftriaxone doses (50 mg/kg, 75 mg/kg, and 100 mg/kg). Sonographic examinations of the gallbladder and urinary tract were performed before treatment on the third and seventh day of therapy, and at the first and second month after the end of treatment. Patients with positive findings were followed with weekly sonographic examinations until the abnormality resolved.Results.Abnormal gallbladder sonograms were demonstrated in 27 children (17%); 16 of them (10%) had gallbladder lithiasis, 11 had gallbladder sludge (7%) (n = 4 on the third day, n = 23 on the seventh day), and 1 developed urolithiasis (0.6%). Five children (19%) were symptomatic. The abnormalities resolved after a mean of 16 days (range 10–30 days). Patients with pseudolithiasis were older and treated with higher drug doses than those with normal sonographic findings (P < 0.01 and P < 0.05, respectively).Abnormal gallbladder sonograms were demonstrated in 27 children (17%); 16 of them (10%) had gallbladder lithiasis, 11 had gallbladder sludge (7%) (n = 4 on the third day, n = 23 on the seventh day), and 1 developed urolithiasis (0.6%). Five children (19%) were symptomatic. The abnormalities resolved after a mean of 16 days (range 10–30 days). Patients with pseudolithiasis were older and treated with higher drug doses than those with normal sonographic findings (P < 0.01 and P < 0.05, respectively).Conclusions.Biliary pseudolithiasis (and infrequently nephrolithiasis) usually occurs in children receiving high doses of ceftriaxone. It is generally asymptomatic. When this reversible complication becomes symptomatic, unnecessary cholecystectomy should be avoided. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound 34:217–222, 2006Biliary pseudolithiasis (and infrequently nephrolithiasis) usually occurs in children receiving high doses of ceftriaxone. It is generally asymptomatic. When this reversible complication becomes symptomatic, unnecessary cholecystectomy should be avoided. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound 34:217–222, 2006
Pediatric Neurosurgery, 2009
identified in 67 (19.8%) of the 338 CCT scans. Twenty of the 67 patients (29.9%) with CCT scan ab... more identified in 67 (19.8%) of the 338 CCT scans. Twenty of the 67 patients (29.9%) with CCT scan abnormality had no clinical signs. Of all cases, 125 (13.6%) were hospitalized, 617 (67.4%) were treated as outpatients, and 174 (19.0%) left the emergency department based on a personal decision. Conclusion: Some clinical risk factors can be used as predictors of abnormalities in CCT scans following MHI, but the absence of such clinical findings does not exclude the possibility of intracranial injuries.
ocukta dermatolojik aciller: 5 yıllık deneyim
... Olguların 4'ü (%0.8) yenidoğan, 70'i (%14.1) süt çocuğu, 161'i (%3... more ... Olguların 4'ü (%0.8) yenidoğan, 70'i (%14.1) süt çocuğu, 161'i (%32.3) oyun çocuğu ve 263'ü (%52.8) ise okul çocuğu idi ... Dermatological emergencies in childhood: 5 years experience AhmetGüzel 1 , Serap Karasalihoğlu 1 , Esra Hazar Sayar 1 , Özer Arıcan 2 , Cemil Kavalcı 3 ...
Emergency Peripartum Hysterectomy: 16-year Experience of a Medical Hospital
Journal of The Chinese Medical Association, 2010
We conducted this retrospective study to evaluate the outcomes and indications of emergency perip... more We conducted this retrospective study to evaluate the outcomes and indications of emergency peripartum hysterectomy (EPH) as a life-saving procedure. We analyzed a series of 140 cases of EPH, between January 1993 and December 2008 in our clinic, retrospectively. The data were collected from the patients&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; files. The incidence, demographic characteristics, risk factors, indications and outcomes of hysterectomy, peripartum complications, the operation types, maternal morbidity and mortality and fetal mortality were evaluated. A total of 26,015 of women were delivered. The incidence of EPH was 5.38 per 1,000 deliveries. The mean age was 34.19 +/- 6.04 years (range, 21-49 years), gravidity was 6.84 +/- 3.38 (1-17) and parity was 5.58 +/- 3.04 (0-15). Of the 140 cases, 90 were delivered by cesarean section [29 (20.71%) of these had had a previous cesarean section] and 50 were vaginally delivered. One hundred and five cases had subtotal hysterectomy and 35 had total abdominal hysterectomy. The most common indications for EPH were uterine atony followed by uterine rupture and abnormal placentation. Mean operation time was 142.23 +/- 43.70 minutes. The average blood transfusion was 4.79 +/- 3.36 (1-14) units. Relaparotomy was performed in 23 cases. Maternal mortality was seen in 13 cases. Seventy-nine of the cases delivered at an outside center and were referred to our clinic for the intensive care unit. Sixty-one of the cases delivered at our clinic and 31 had stillbirths. This study suggests that the most common indications for EPH are uterine atony, uterine rupture and abnormal placentation. This is probably due to the advanced age of pregnancies and multiparity in our region. Therefore, we believe that the risk of EPH may be decreased with appropriate and closer prenatal care as well as education of the pregnant women.
Taiwanese Journal of Obstetrics & Gynecology, 2011
Placental site trophoblastic tumors (PSTTs) are an extremely rare form of gestational trophoblast... more Placental site trophoblastic tumors (PSTTs) are an extremely rare form of gestational trophoblastic disease (GTD). Marchand and Ewing made the first observations in 1895 and 1910, respectively, and Kurman and Scully described the clinical and pathological characteristics of PSTTs in 1976, when the term trophoblastic pseudotumor was adopted to characterize the apparently benign nature of the disease [1,2]. Subsequent case reports have presented evidence of a sometimes aggressive, malignant, and fatal course of the disease, and the name was changed to PSTT in 1981 [3]. Histopathologically, PSTTs are characterized by a neoplastic monomorphic population of implantation-like intermediate trophoblastic cells, often as sheets of polyhedral, rounded, or occasionally spindle-shaped cells that infiltrate the myometrium extensively. Because of the rarity of this type of tumor, there is little information about its epidemiology and etiology, and few large series on diagnosis and treatment have been published . PSTTs are most often seen in patients of reproductive age and can follow a normal pregnancy, miscarriage, or GTD. Irregular vaginal bleeding is the most common presenting feature, although a wide range of other symptoms has also been reported, including galactorrhea, virilization, nephrotic syndrome, and polycythemia . We report two cases of PSTT treated successfully in our clinic.
Scalp Dermatophyte Carriage in Pregnant, Pre, and Postmenopausal Women: A Comparative Study Using the Hairbrush and Cytobrush Methods of Sample Collection
Mycopathologia, 2011
Tinea capitis is a dermatophyte infection of the scalp that is most often seen in prepubescent ch... more Tinea capitis is a dermatophyte infection of the scalp that is most often seen in prepubescent children. In this investigation, we examined the prevalence of tinea capitis and symptom-free colonization of the scalp with dermatophytes in 786 pre- and postmenopausal women aged 12–84 years. Scalp samples were collected from all participants by cytobrush or hairbrush, and cultures were then grown from these samples on Sabouraud glucose agar. No participant was diagnosed with tinea capitis; however, one 43-year-old patient (0.1%) was positive for a “scalp carriage” related to anthropophilic Trichophyton rubrum, as detected using a hairbrush. The internal transcribed spacer (ITS) regions of the isolate were sequenced, and the assembled DNA sequences were examined using the basic BLAST (nucleotide–nucleotide) software of the National Center for Biotechnology Information Web database. This patient was followed up without any antimycotic treatment, and after 4 weeks, mycological clearance was documented. In addition, the contacts and environment at home were screened, where all fungal cultures were sterile. To the best of our knowledge, this study is the first report of a “scalp carriage” related to a cosmopolitan fungus, T. rubrum.
BACKGROUND: It is reported that prevalence of overweight and obesity have increased in all age gr... more BACKGROUND: It is reported that prevalence of overweight and obesity have increased in all age groups, but little is known about prevalence of overweight and obesity in preschool children. Therefore, the purpose of this study was to survey the prevalence of underweight, overweight and obesity in 3-6 year-old Tehranian children in 2009-2010.
Biner B, Çeltik C, Öner N, Küçükuğurluoğlu Y, Güzel A, Yıldırım Ç, Adalı MK. The comparison of si... more Biner B, Çeltik C, Öner N, Küçükuğurluoğlu Y, Güzel A, Yıldırım Ç, Adalı MK. The comparison of single-dose ceftriaxone, five-day azithromycin, and ten-day amoxicillin/clavulanate for the treatment of children with acute otitis media. Turk J Pediatr 2007; 49: 390-396. The aim of the study was to evaluate the efficacy of short-course antimicrobial therapies [single intramuscular dose of ceftriaxone (50 mg/kg, not exceeding 1 g), 5 days of azithromycin (10 mg/kg on day 1, then 5 mg/kg daily on days 2-5) and the traditional 10-day course of amoxicillin/clavulanate (90/6.4 mg/kg/day in 2 doses)] in children with acute otitis media (AOM). The study was conducted as a prospective, comparative, open randomized trial between February 2001 and April 2003, and 104 children were enrolled, with a mean age of 3.8 (2.3) years.
Ceftriaxone-associated biliary pseudolithiasis in children
Journal of Clinical Ultrasound, 2006
Purpose.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in th... more Purpose.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in the gallbladder and urinary tract. The aim of this study was to investigate the incidence and predisposing factors that contribute to this side effect.Ceftriaxone is known to induce reversible precipitations, known as pseudolithiasis, in the gallbladder and urinary tract. The aim of this study was to investigate the incidence and predisposing factors that contribute to this side effect.Methods.A prospective study was conducted in 156 children admitted for the treatment of various infections with different daily ceftriaxone doses (50 mg/kg, 75 mg/kg, and 100 mg/kg). Sonographic examinations of the gallbladder and urinary tract were performed before treatment on the third and seventh day of therapy, and at the first and second month after the end of treatment. Patients with positive findings were followed with weekly sonographic examinations until the abnormality resolved.A prospective study was conducted in 156 children admitted for the treatment of various infections with different daily ceftriaxone doses (50 mg/kg, 75 mg/kg, and 100 mg/kg). Sonographic examinations of the gallbladder and urinary tract were performed before treatment on the third and seventh day of therapy, and at the first and second month after the end of treatment. Patients with positive findings were followed with weekly sonographic examinations until the abnormality resolved.Results.Abnormal gallbladder sonograms were demonstrated in 27 children (17%); 16 of them (10%) had gallbladder lithiasis, 11 had gallbladder sludge (7%) (n = 4 on the third day, n = 23 on the seventh day), and 1 developed urolithiasis (0.6%). Five children (19%) were symptomatic. The abnormalities resolved after a mean of 16 days (range 10–30 days). Patients with pseudolithiasis were older and treated with higher drug doses than those with normal sonographic findings (P < 0.01 and P < 0.05, respectively).Abnormal gallbladder sonograms were demonstrated in 27 children (17%); 16 of them (10%) had gallbladder lithiasis, 11 had gallbladder sludge (7%) (n = 4 on the third day, n = 23 on the seventh day), and 1 developed urolithiasis (0.6%). Five children (19%) were symptomatic. The abnormalities resolved after a mean of 16 days (range 10–30 days). Patients with pseudolithiasis were older and treated with higher drug doses than those with normal sonographic findings (P < 0.01 and P < 0.05, respectively).Conclusions.Biliary pseudolithiasis (and infrequently nephrolithiasis) usually occurs in children receiving high doses of ceftriaxone. It is generally asymptomatic. When this reversible complication becomes symptomatic, unnecessary cholecystectomy should be avoided. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound 34:217–222, 2006Biliary pseudolithiasis (and infrequently nephrolithiasis) usually occurs in children receiving high doses of ceftriaxone. It is generally asymptomatic. When this reversible complication becomes symptomatic, unnecessary cholecystectomy should be avoided. © 2006 Wiley Periodicals, Inc. J Clin Ultrasound 34:217–222, 2006
Pediatric Neurosurgery, 2009
identified in 67 (19.8%) of the 338 CCT scans. Twenty of the 67 patients (29.9%) with CCT scan ab... more identified in 67 (19.8%) of the 338 CCT scans. Twenty of the 67 patients (29.9%) with CCT scan abnormality had no clinical signs. Of all cases, 125 (13.6%) were hospitalized, 617 (67.4%) were treated as outpatients, and 174 (19.0%) left the emergency department based on a personal decision. Conclusion: Some clinical risk factors can be used as predictors of abnormalities in CCT scans following MHI, but the absence of such clinical findings does not exclude the possibility of intracranial injuries.