GONUL KEMIKLER - Academia.edu (original) (raw)

GONUL KEMIKLER

I am a medical physicist from Istanbul.

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Papers by GONUL KEMIKLER

Research paper thumbnail of DÜZENSİZ TORAKS VE MEDİASTEN ALANLARINA KOBALT-60 ile TELETERAPİ UYGULAMALARINDA KORUMA BLOKLARININ DOZ PARAMETRELERİNE ETKİSİ

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2000

Research paper thumbnail of Absolute dose verification of static intensity modulated radiation therapy (IMRT) with ion chambers of various volumes and TLD detectors

Reports of Practical Oncology & Radiotherapy, 2018

Research paper thumbnail of Dosimetric evaluation of matching Co-60 and electron fields for treatment of head and neck cancers

Research paper thumbnail of Mantle' Tarzi Işinlamalarda 'Set-Up' Hata Varliğinin Port Fi̇lmlerle Araştirilmasi

Research paper thumbnail of Yüksek Enerji̇li̇ Foton Huzmeleri̇ İçi̇n 'Wedge' Faktörleri̇ni̇n Deri̇nli̇k Ve Alan Bağimliliklarinin Araştirilmasi

Research paper thumbnail of Brakiterapide Normalizasyon ve Optimizasyon Yöntemleri

Research paper thumbnail of The relations of radiation induced ultrastructural cardiac damage with serum troponin T and creatin kinase MB levels

European Journal of Cancer, 1997

Research paper thumbnail of Reflections on the Loss of a Friend and Colleague: In memory of Assoc. Prof. İsmail Özbay MD, PhD

Turkish Journal of Oncology, 2019

Research paper thumbnail of Meme kanseri radyoterapi tekniğinin gelişimi

İ. Ü. Onkoloji Enstitüsü Yayınları, 1997

Research paper thumbnail of Radiation Dose to Hippocampus With Increasing Planning Target Volume in Patients With Pituitary Adenoma Treated With Hypofractionated Radiation Therapy

International Journal of Radiation Oncology*Biology*Physics, 2015

Research paper thumbnail of Meme Kanseri̇ Işinlamasinda Alan Bi̇rleşi̇m Problemleri̇ Ve Homojen Işinlamaya Yöneli̇k Tekni̇ği̇n Geli̇şti̇ri̇lmesi̇

Research paper thumbnail of A comparison between surgical scar and clips-guided treatment plans in

OBJECTIVES: In general, breast electron boost treatment planning is made using surgical scars or ... more OBJECTIVES: In general, breast electron boost treatment planning is made using surgical scars or clips placed in the tumor bed. The aim of this study was to compare these two treatments plans in terms of dose optimization. METHODS: Twenty-five patients who had surgical clips placed in the tumor bed during tumor excision were evaluated. At first, surgical clips were not taken into account in these patients (type I). In the secondary stage, the treatment plan (type II) was performed considering surgical clips. Taking type II treatment plan as a basis, type I treatment plan was compared in terms of energy, field size, gantry angle, collimator angle and field center parameters. RESULTS: When compared with Type I plan, changes were observed in the electron energy used in the treatment of 12 patients, the electron fields of 20 patients, the gantry angles of 12 patients, the collimator angles of 6 patients and the field centers of 18 patients when surgical clips were considered. CONCLUSION...

Research paper thumbnail of Must Radiation Therapy Be the Last Choice in the Treatment of Patients With Acromegaly?

International Journal of Radiation Oncology*Biology*Physics, 2016

Research paper thumbnail of PO-400 the Clinical Applications of Surface HDR Leipzig Applicators

Radiotherapy and Oncology, 2012

Research paper thumbnail of PO-300 Dosimetric Comparison of 2D and 3D Brachytherapy Planning

Radiotherapy and Oncology, 2012

Research paper thumbnail of 61 An examinationo f cardiac doses in radiotherapy of the breast cancer patients

Radiotherapy and Oncology, 1996

Research paper thumbnail of Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breast reconstruction?

World Journal of Surgical Oncology, 2012

Background The optimum protocol for expander volume adjustment with respect to the timing and app... more Background The optimum protocol for expander volume adjustment with respect to the timing and application of radiotherapy remains controversial. Methods Eighteen New Zealand rabbits were divided into three groups. Metallic port integrated anatomic breast expanders of 250 cc were implanted on the back of each animal and controlled expansion was performed. Group I underwent radiotherapy with full expanders while in Group II, expanders were partially deflated immediately prior to radiotherapy. Control group did not receive radiotherapy. The changes in blood flow at different volume adjustments were investigated in Group II by laser Doppler flowmetry. Variations in the histopathologic properties of the irradiated tissues including the skin, capsule and the pocket floor, were compared in the biopsy specimens taken from different locations in each group. Results A significant increase in skin blood flow was detected in Group II with partial expander deflation. Overall, histopathologic exa...

Research paper thumbnail of Open Access

Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breas... more Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breast reconstruction?

Research paper thumbnail of Patient-specific quality assurance for intracranial cases in robotic radiosurgery system

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 2018

PURPOSE The purpose of this study was to perform pretreatment patient-specific quality assurance ... more PURPOSE The purpose of this study was to perform pretreatment patient-specific quality assurance (QA) for intracranial irradiation using CyberKnife with an ion chamber. METHODS Twenty-five intracranial plans created using the ray-tracing algorithm were used for this study. Computed tomography (CT) images of the water-equivalent RW3 slab phantom with PinPoint ionization chamber were acquired with 1-mm slice thickness and transferred to the MultiPlan treatment planning system (TPS). Four gold fiducial markers embedded into two different plates were used to tracking during the irradiation. Intracranial plans were transferred to CT images of the RW3 phantom. The isodose curves and sensitive volume of ion chamber were overlapped. Point dose measurements were performed three times and the mean point doses were calculated for each plan. The mean doses measured by the PinPoint ion chamber were compared with those of the calculated by MultiPlan TPS in the sensitive volume of PinPoint. RESULT...

Research paper thumbnail of The Analysis of Depth and Field Dependence of 'Wedge' Factors for High Energy Photon Beams

Wedge' filters are used to compensate for missing tissue and to optimize isodose distribution... more Wedge' filters are used to compensate for missing tissue and to optimize isodose distribution to target volumes. The original photon energy spectrum changes due to 'wedge' filter because of scattering of primary photons. As such it becomes essential to account for the dependence of the 'wedge' factor on depth and field size in clinical dose calculation. The aim of this study is the determination of 'wedge' factors as a function of field size and phantom depth for Co-60 gamma-ray and X-ray beams in the range of 4, 6 and 15 MV containing 15°-60° brass and tungsten 'wedge' filters. For Co-60 and 4 MV X-ray beams standard 'wedge' filters with angles ranging between 15°-60°; for 6 MV and 15 MV X-ray beams only one 'wedge' filter with an angle of 60° have been used. Wedge factors have been found by the help of the proportion of wedge values to open field values under the same conditions. In order to search field and depth dependence rela...

Research paper thumbnail of DÜZENSİZ TORAKS VE MEDİASTEN ALANLARINA KOBALT-60 ile TELETERAPİ UYGULAMALARINDA KORUMA BLOKLARININ DOZ PARAMETRELERİNE ETKİSİ

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2000

Research paper thumbnail of Absolute dose verification of static intensity modulated radiation therapy (IMRT) with ion chambers of various volumes and TLD detectors

Reports of Practical Oncology & Radiotherapy, 2018

Research paper thumbnail of Dosimetric evaluation of matching Co-60 and electron fields for treatment of head and neck cancers

Research paper thumbnail of Mantle' Tarzi Işinlamalarda 'Set-Up' Hata Varliğinin Port Fi̇lmlerle Araştirilmasi

Research paper thumbnail of Yüksek Enerji̇li̇ Foton Huzmeleri̇ İçi̇n 'Wedge' Faktörleri̇ni̇n Deri̇nli̇k Ve Alan Bağimliliklarinin Araştirilmasi

Research paper thumbnail of Brakiterapide Normalizasyon ve Optimizasyon Yöntemleri

Research paper thumbnail of The relations of radiation induced ultrastructural cardiac damage with serum troponin T and creatin kinase MB levels

European Journal of Cancer, 1997

Research paper thumbnail of Reflections on the Loss of a Friend and Colleague: In memory of Assoc. Prof. İsmail Özbay MD, PhD

Turkish Journal of Oncology, 2019

Research paper thumbnail of Meme kanseri radyoterapi tekniğinin gelişimi

İ. Ü. Onkoloji Enstitüsü Yayınları, 1997

Research paper thumbnail of Radiation Dose to Hippocampus With Increasing Planning Target Volume in Patients With Pituitary Adenoma Treated With Hypofractionated Radiation Therapy

International Journal of Radiation Oncology*Biology*Physics, 2015

Research paper thumbnail of Meme Kanseri̇ Işinlamasinda Alan Bi̇rleşi̇m Problemleri̇ Ve Homojen Işinlamaya Yöneli̇k Tekni̇ği̇n Geli̇şti̇ri̇lmesi̇

Research paper thumbnail of A comparison between surgical scar and clips-guided treatment plans in

OBJECTIVES: In general, breast electron boost treatment planning is made using surgical scars or ... more OBJECTIVES: In general, breast electron boost treatment planning is made using surgical scars or clips placed in the tumor bed. The aim of this study was to compare these two treatments plans in terms of dose optimization. METHODS: Twenty-five patients who had surgical clips placed in the tumor bed during tumor excision were evaluated. At first, surgical clips were not taken into account in these patients (type I). In the secondary stage, the treatment plan (type II) was performed considering surgical clips. Taking type II treatment plan as a basis, type I treatment plan was compared in terms of energy, field size, gantry angle, collimator angle and field center parameters. RESULTS: When compared with Type I plan, changes were observed in the electron energy used in the treatment of 12 patients, the electron fields of 20 patients, the gantry angles of 12 patients, the collimator angles of 6 patients and the field centers of 18 patients when surgical clips were considered. CONCLUSION...

Research paper thumbnail of Must Radiation Therapy Be the Last Choice in the Treatment of Patients With Acromegaly?

International Journal of Radiation Oncology*Biology*Physics, 2016

Research paper thumbnail of PO-400 the Clinical Applications of Surface HDR Leipzig Applicators

Radiotherapy and Oncology, 2012

Research paper thumbnail of PO-300 Dosimetric Comparison of 2D and 3D Brachytherapy Planning

Radiotherapy and Oncology, 2012

Research paper thumbnail of 61 An examinationo f cardiac doses in radiotherapy of the breast cancer patients

Radiotherapy and Oncology, 1996

Research paper thumbnail of Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breast reconstruction?

World Journal of Surgical Oncology, 2012

Background The optimum protocol for expander volume adjustment with respect to the timing and app... more Background The optimum protocol for expander volume adjustment with respect to the timing and application of radiotherapy remains controversial. Methods Eighteen New Zealand rabbits were divided into three groups. Metallic port integrated anatomic breast expanders of 250 cc were implanted on the back of each animal and controlled expansion was performed. Group I underwent radiotherapy with full expanders while in Group II, expanders were partially deflated immediately prior to radiotherapy. Control group did not receive radiotherapy. The changes in blood flow at different volume adjustments were investigated in Group II by laser Doppler flowmetry. Variations in the histopathologic properties of the irradiated tissues including the skin, capsule and the pocket floor, were compared in the biopsy specimens taken from different locations in each group. Results A significant increase in skin blood flow was detected in Group II with partial expander deflation. Overall, histopathologic exa...

Research paper thumbnail of Open Access

Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breas... more Does partial expander deflation exacerbate the adverse effects of radiotherapy in two-stage breast reconstruction?

Research paper thumbnail of Patient-specific quality assurance for intracranial cases in robotic radiosurgery system

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 2018

PURPOSE The purpose of this study was to perform pretreatment patient-specific quality assurance ... more PURPOSE The purpose of this study was to perform pretreatment patient-specific quality assurance (QA) for intracranial irradiation using CyberKnife with an ion chamber. METHODS Twenty-five intracranial plans created using the ray-tracing algorithm were used for this study. Computed tomography (CT) images of the water-equivalent RW3 slab phantom with PinPoint ionization chamber were acquired with 1-mm slice thickness and transferred to the MultiPlan treatment planning system (TPS). Four gold fiducial markers embedded into two different plates were used to tracking during the irradiation. Intracranial plans were transferred to CT images of the RW3 phantom. The isodose curves and sensitive volume of ion chamber were overlapped. Point dose measurements were performed three times and the mean point doses were calculated for each plan. The mean doses measured by the PinPoint ion chamber were compared with those of the calculated by MultiPlan TPS in the sensitive volume of PinPoint. RESULT...

Research paper thumbnail of The Analysis of Depth and Field Dependence of 'Wedge' Factors for High Energy Photon Beams

Wedge' filters are used to compensate for missing tissue and to optimize isodose distribution... more Wedge' filters are used to compensate for missing tissue and to optimize isodose distribution to target volumes. The original photon energy spectrum changes due to 'wedge' filter because of scattering of primary photons. As such it becomes essential to account for the dependence of the 'wedge' factor on depth and field size in clinical dose calculation. The aim of this study is the determination of 'wedge' factors as a function of field size and phantom depth for Co-60 gamma-ray and X-ray beams in the range of 4, 6 and 15 MV containing 15°-60° brass and tungsten 'wedge' filters. For Co-60 and 4 MV X-ray beams standard 'wedge' filters with angles ranging between 15°-60°; for 6 MV and 15 MV X-ray beams only one 'wedge' filter with an angle of 60° have been used. Wedge factors have been found by the help of the proportion of wedge values to open field values under the same conditions. In order to search field and depth dependence rela...

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