Ga Eun Lee - Academia.edu (original) (raw)

Talks by Ga Eun Lee

A proposal to conduct a systematic review asking the research question: "Are patients with active... more A proposal to conduct a systematic review asking the research question: "Are patients with active TB who have mental illness at greater risk for poor TB treatment outcomes (failure, death, default) compared to patients without mental illness?"

Papers by Ga Eun Lee

JAMA Network Open

IMPORTANCE Causes of death in children with birth defects are poorly understood. OBJECTIVE To det... more IMPORTANCE Causes of death in children with birth defects are poorly understood. OBJECTIVE To determine mortality rates by cause of death in children with and without birth defects. DESIGN, SETTING, AND PARTICIPANTS This longitudinal cohort study included a populationbased sample of 1 037 688 children and was conducted in all hospitals in Quebec, Canada, with 7 700 596 person-years of follow-up between birth and age 14 years (April 1, 2006, to March 31, 2020). EXPOSURES Presence or absence of a birth defect. MAIN OUTCOMES AND MEASURES Outcomes were all-cause and cause-specific mortality. Hazard ratios (HRs) and 95% CIs were computed for the association between birth defects and mortality with Cox proportional hazards models adjusted for patient characteristics. RESULTS Among the 1 037 688 children in the cohort, 95 566 had birth defects (56.5% boys). There were 532 542 boys in the cohort (51.3%), and mean (SD) age at the end of follow-up was 7.42 (3.72) years. There were 918 deaths among children with defects, and the mean (SD) age was 0.93 (2.07) years at death; there were 1082 deaths among the 942 122 children without defects, and the mean (SD) age at death was 0.50 (1.51) years. Mortality rates were higher for children with birth defects compared with no defect (1.3 vs 0.2 deaths per 1000 person-years, respectively). Girls (HR, 5.66; 95% CI, 4.96-6.47) and boys (HR, 4.69; 95% CI, 4.15-5.29) with birth defects had an elevated risk of death before 14 years compared with unaffected children. Birth defects were associated with mortality from circulatory (HR, 26.59; 95% CI, 17.73-39.87), respiratory (HR, 23.03; 95% CI, 15.09-35.14), and digestive causes (HR, 31.77; 95% CI, 11.87-85.04), but anomalies were rarely listed as the cause of death. Compared with children with no defect, those with birth defects were at greatest risk of death between 28 and 364 days of life. CONCLUSIONS AND RELEVANCE This cohort study of 1 037 688 children suggests that birth defects were strongly associated with mortality owing to circulatory, respiratory, and digestive causes. This finding suggests that the contribution of birth defects may be underestimated in mortality statistics.

PLOS ONE

Background Mobile health (mHealth) technologies are innovative solutions for delivering instructi... more Background Mobile health (mHealth) technologies are innovative solutions for delivering instructions to patients preparing for colonoscopy. Objective To systematically review the literature evaluating the effectiveness of mHealth technologies supporting colonoscopy preparation on patient and clinical outcomes. Methods MEDLINE, EMBASE, CINAHL and CENTRAL were searched for randomized controlled trials (RCTs) that evaluated the effectiveness of mHealth technologies for colonoscopy preparation on patient and clinical outcomes. Two reviewers independently assessed study eligibility, extracted data, and appraised methodological quality using the Cochrane Risk-of-Bias tool. Data were pooled using random effects models and when heterogeneity, assessed using I2, was statistically significant, a qualitative synthesis of the data was performed. Publication bias was assessed using a funnel plot. Results Ten RCTs (3,383 participants) met inclusion criteria. MHealth interventions included smartph...

Journal of Interpersonal Violence

Pregnancy outcomes of women with serious injuries due to violence receive limited attention. We e... more Pregnancy outcomes of women with serious injuries due to violence receive limited attention. We examined the association of assault before and during pregnancy with maternal and infant outcomes at delivery. We performed a retrospective cohort study of 2,193,711 births in Quebec, Canada between 1989 and 2016. We identified women who were hospitalized for physical assault, sexual assault, and assault with documented intimate partner violence before and during pregnancy. We examined adverse outcomes at delivery, including preeclampsia, placental abruption, antepartum hemorrhage, stillbirth, preterm birth, low birthweight, and other disorders. In log-binomial regression models, we estimated risk ratios (RR) and 95% confidence intervals (CI) for the association between violence hospitalization and adverse birth outcomes, adjusted for potential confounders. Compared with no exposure, violence before or during pregnancy was associated with the future risk of placental abruption (RR 1.49, 9...

Annals of Allergy, Asthma & Immunology

The Journal of Pediatrics

Journal of Addiction Medicine

Health Reform Observer - Observatoire des Réformes de Santé

Despite various health reforms over the last 20 years, access to primary care remained stagnant i... more Despite various health reforms over the last 20 years, access to primary care remained stagnant in Québec, and in 2014 the province had the highest proportion of residents in Canada without a family physician. In November 2014, the Québec Minister of Health and Social Services introduced Bill 20, An Act to promote access to family medicine and specialized medicine services and to amend various legislative provisions relating to assisted procreation. Bill 20 aimed to increase access to family medicine through a system of quotas of registered patients and penalties for family physicians. Health system user support groups and the governmental advisory group on women's rights supported Bill 20's approach to ensure the rights of system users to access family physicians. However, the union of general practitioners was strongly against the bill due to the clash between the minister's reliance on numbers and the realities of family practice. The union of general practitioners entered negotiations with the minister and while Bill 20 was legalized in 2015, it was agreed that family physicians would be excused from the bill as long as they reached two targets at the end of December 2017: 1) 85% of Québecers must have a family doctor and 2) family doctors must ensure the patients registered to them see them, and not other doctors, 80% of the time. The targets were not met at the end of December 2017 but the quota system in Bill 20 has yet to be implemented.

BACKGROUND The preparation for colonoscopy is elaborate and complex. In the context of colorectal... more BACKGROUND The preparation for colonoscopy is elaborate and complex. In the context of colorectal cancer screening, up to 11% of patients do not keep their colonoscopy appointments and up to 33% of those attending their appointments have inadequately cleansed bowels that can delay cancer diagnosis and treatment. A smartphone app may be an acceptable and wide-reaching tool to improve patient adherence to colonoscopy. OBJECTIVE The aim of this qualitative study was to employ a user-centered approach to design the content and features of a smartphone app called colonAPPscopy to support individuals preparing for their colonoscopy appointments. METHODS We conducted 2 focus group discussions (FGDs) with gastroenterology patients treated at the McGill University Health Centre in Montreal, Canada. Patients were aged 50 to 75 years, were English- or French-speaking, and had undergone outpatient colonoscopy in the previous 3 months; they did not have inflammatory bowel disease or colorectal c...

European Journal of Epidemiology

Health Reform Observer - Observatoire des Réformes de Santé

A proposal to conduct a systematic review asking the research question: "Are patients with active... more A proposal to conduct a systematic review asking the research question: "Are patients with active TB who have mental illness at greater risk for poor TB treatment outcomes (failure, death, default) compared to patients without mental illness?"

JAMA Network Open

IMPORTANCE Causes of death in children with birth defects are poorly understood. OBJECTIVE To det... more IMPORTANCE Causes of death in children with birth defects are poorly understood. OBJECTIVE To determine mortality rates by cause of death in children with and without birth defects. DESIGN, SETTING, AND PARTICIPANTS This longitudinal cohort study included a populationbased sample of 1 037 688 children and was conducted in all hospitals in Quebec, Canada, with 7 700 596 person-years of follow-up between birth and age 14 years (April 1, 2006, to March 31, 2020). EXPOSURES Presence or absence of a birth defect. MAIN OUTCOMES AND MEASURES Outcomes were all-cause and cause-specific mortality. Hazard ratios (HRs) and 95% CIs were computed for the association between birth defects and mortality with Cox proportional hazards models adjusted for patient characteristics. RESULTS Among the 1 037 688 children in the cohort, 95 566 had birth defects (56.5% boys). There were 532 542 boys in the cohort (51.3%), and mean (SD) age at the end of follow-up was 7.42 (3.72) years. There were 918 deaths among children with defects, and the mean (SD) age was 0.93 (2.07) years at death; there were 1082 deaths among the 942 122 children without defects, and the mean (SD) age at death was 0.50 (1.51) years. Mortality rates were higher for children with birth defects compared with no defect (1.3 vs 0.2 deaths per 1000 person-years, respectively). Girls (HR, 5.66; 95% CI, 4.96-6.47) and boys (HR, 4.69; 95% CI, 4.15-5.29) with birth defects had an elevated risk of death before 14 years compared with unaffected children. Birth defects were associated with mortality from circulatory (HR, 26.59; 95% CI, 17.73-39.87), respiratory (HR, 23.03; 95% CI, 15.09-35.14), and digestive causes (HR, 31.77; 95% CI, 11.87-85.04), but anomalies were rarely listed as the cause of death. Compared with children with no defect, those with birth defects were at greatest risk of death between 28 and 364 days of life. CONCLUSIONS AND RELEVANCE This cohort study of 1 037 688 children suggests that birth defects were strongly associated with mortality owing to circulatory, respiratory, and digestive causes. This finding suggests that the contribution of birth defects may be underestimated in mortality statistics.

PLOS ONE

Background Mobile health (mHealth) technologies are innovative solutions for delivering instructi... more Background Mobile health (mHealth) technologies are innovative solutions for delivering instructions to patients preparing for colonoscopy. Objective To systematically review the literature evaluating the effectiveness of mHealth technologies supporting colonoscopy preparation on patient and clinical outcomes. Methods MEDLINE, EMBASE, CINAHL and CENTRAL were searched for randomized controlled trials (RCTs) that evaluated the effectiveness of mHealth technologies for colonoscopy preparation on patient and clinical outcomes. Two reviewers independently assessed study eligibility, extracted data, and appraised methodological quality using the Cochrane Risk-of-Bias tool. Data were pooled using random effects models and when heterogeneity, assessed using I2, was statistically significant, a qualitative synthesis of the data was performed. Publication bias was assessed using a funnel plot. Results Ten RCTs (3,383 participants) met inclusion criteria. MHealth interventions included smartph...

Journal of Interpersonal Violence

Pregnancy outcomes of women with serious injuries due to violence receive limited attention. We e... more Pregnancy outcomes of women with serious injuries due to violence receive limited attention. We examined the association of assault before and during pregnancy with maternal and infant outcomes at delivery. We performed a retrospective cohort study of 2,193,711 births in Quebec, Canada between 1989 and 2016. We identified women who were hospitalized for physical assault, sexual assault, and assault with documented intimate partner violence before and during pregnancy. We examined adverse outcomes at delivery, including preeclampsia, placental abruption, antepartum hemorrhage, stillbirth, preterm birth, low birthweight, and other disorders. In log-binomial regression models, we estimated risk ratios (RR) and 95% confidence intervals (CI) for the association between violence hospitalization and adverse birth outcomes, adjusted for potential confounders. Compared with no exposure, violence before or during pregnancy was associated with the future risk of placental abruption (RR 1.49, 9...

Annals of Allergy, Asthma & Immunology

The Journal of Pediatrics

Journal of Addiction Medicine

Health Reform Observer - Observatoire des Réformes de Santé

Despite various health reforms over the last 20 years, access to primary care remained stagnant i... more Despite various health reforms over the last 20 years, access to primary care remained stagnant in Québec, and in 2014 the province had the highest proportion of residents in Canada without a family physician. In November 2014, the Québec Minister of Health and Social Services introduced Bill 20, An Act to promote access to family medicine and specialized medicine services and to amend various legislative provisions relating to assisted procreation. Bill 20 aimed to increase access to family medicine through a system of quotas of registered patients and penalties for family physicians. Health system user support groups and the governmental advisory group on women's rights supported Bill 20's approach to ensure the rights of system users to access family physicians. However, the union of general practitioners was strongly against the bill due to the clash between the minister's reliance on numbers and the realities of family practice. The union of general practitioners entered negotiations with the minister and while Bill 20 was legalized in 2015, it was agreed that family physicians would be excused from the bill as long as they reached two targets at the end of December 2017: 1) 85% of Québecers must have a family doctor and 2) family doctors must ensure the patients registered to them see them, and not other doctors, 80% of the time. The targets were not met at the end of December 2017 but the quota system in Bill 20 has yet to be implemented.

BACKGROUND The preparation for colonoscopy is elaborate and complex. In the context of colorectal... more BACKGROUND The preparation for colonoscopy is elaborate and complex. In the context of colorectal cancer screening, up to 11% of patients do not keep their colonoscopy appointments and up to 33% of those attending their appointments have inadequately cleansed bowels that can delay cancer diagnosis and treatment. A smartphone app may be an acceptable and wide-reaching tool to improve patient adherence to colonoscopy. OBJECTIVE The aim of this qualitative study was to employ a user-centered approach to design the content and features of a smartphone app called colonAPPscopy to support individuals preparing for their colonoscopy appointments. METHODS We conducted 2 focus group discussions (FGDs) with gastroenterology patients treated at the McGill University Health Centre in Montreal, Canada. Patients were aged 50 to 75 years, were English- or French-speaking, and had undergone outpatient colonoscopy in the previous 3 months; they did not have inflammatory bowel disease or colorectal c...

European Journal of Epidemiology

Health Reform Observer - Observatoire des Réformes de Santé