Gabriel Dusing - Academia.edu (original) (raw)

Papers by Gabriel Dusing

medRxiv (Cold Spring Harbor Laboratory), Jun 19, 2024

In the preparation of this manuscript, the AI tool ChatGPT, developed by OpenAI, was utilized for... more In the preparation of this manuscript, the AI tool ChatGPT, developed by OpenAI, was utilized for summarizing content, streamlining sentences, structuring sections, and answering specific queries related to the text. The use of ChatGPT facilitated the enhancement of the manuscript's clarity and logical coherence. However, the authors assume full responsibility for the final content and ethical compliance with publication standards. ChatGPT was not used for the collection and analysis of data or the production of images or graphical elements.

Research Square (Research Square), Apr 27, 2024

Increases in ambient temperature have been associated with deleterious consequences for socially ... more Increases in ambient temperature have been associated with deleterious consequences for socially disadvantaged populations. However, there is limited research on the associated mental health effects. Thus, this study examined the direct and indirect effects of high temperatures on sleep quality and cognitive function among older adults. Using combined data from the WHO Ghana Study on Global Ageing and Adult Health with temperature measurements derived from the Climatic Research Unit gridded Time Series and structural equation models, we examined the direct and indirect relationship between increasing mean temperatures, sleep di culties, and cognitive impairment while adjusting for appropriate covariates. Increases in mean temperature change were associated with an increase in the severity of sleep di culties and a decrease in cognitive function. The effect of temperature signi cantly increased sleep di culties for females and older adults (65+). Our study shows that a reduction in temperature will improve sleep quality and enhance cognitive function.

Social psychiatry and psychiatric epidemiology, Mar 1, 2024

Journal of Affective Disorders, Dec 31, 2023

Research Square (Research Square), Feb 28, 2024

Noncommunicable diseases (NCDs) such as hypertension and diabetes mellitus, disproportionately af... more Noncommunicable diseases (NCDs) such as hypertension and diabetes mellitus, disproportionately affect socially disadvantaged populations in LMICs. Airborne ne particulate matter (PM2.5) has been shown to contribute to NCD risk, yet few studies have examined this effect and its variations by gender and geography in sub-Saharan Africa. We linked the Ghana data of the World Health Organization's Study on Global AGEing and Adult Health to satellite-recorded PM2.5 concentrations to examine the gendered and geographical relationship between exposure to atmospheric PM2.5 and NCDs among older adults. Increasing atmospheric PM2.5 exposure was associated with higher NCD risk with signi cant gendered and geographical differences. A unit increase in atmospheric PM2.5 increased the relative risk ratios (RRRs) of women by 1

BMC Public Health, May 25, 2023

Background Employment conditions may affect individuals' leisure-time physical activity (LTPA). W... more Background Employment conditions may affect individuals' leisure-time physical activity (LTPA). We aimed to examine the relationship between changes in working and employment conditions and LTPA among working-age populations in South Korea from 2009 to 2019. Methods A cohort of 6,553 men and 5,124 women aged 19-64 years was analyzed using linear individual-level fixedeffects regressions to examine changes in working and employment conditions with changes in LTPA. Results Reduced working hours, labor union membership, and part-time work were associated with increased LTPA for both sexes. Manual labor and self-reported precarious work were associated with reduced LTPA. The longitudinal relationship between employment conditions and LTPA was clear in men, but less apparent in women. Conclusions Changes in working and employment conditions had longitudinal associations with changes in LTPA among working-age Koreans. Future research should examine changing employment conditions and their effect on LTPA, particularly among women and manual/precarious workers. These results could inform effective planning and interventions to increase LTPA.

Psychological Medicine, Jun 22, 2023

Background. Recreational cannabis policies are being considered in many jurisdictions internation... more Background. Recreational cannabis policies are being considered in many jurisdictions internationally. Given that cannabis use is more prevalent among people with depression, legalisation may lead to more adverse events in this population. Cannabis legalisation in Canada included the legalisation of flower and herbs (phase 1) in October 2018, and the deregulation of cannabis edibles one year later (phase 2). This study investigated disparities in cannabis-related emergency department (ED) visits in depressed and non-depressed individuals in each phase. Methods. Using administrative data, we identified all adults diagnosed with depression 60 months prior to legalisation (n = 929 844). A non-depressed comparison group was identified using propensity score matching. We compared the pre-post policy differences in cannabisrelated ED-visits in depressed individuals v. matched (and unmatched) non-depressed individuals. Results. In the matched sample (i.e. comparison with non-depressed people similar to the depressed group), people with depression had approximately four times higher risk of cannabis-related ED-visits relative to the non-depressed over the entire period. Phases 1 and 2 were not associated with any changes in the matched depressed and non-depressed groups. In the unmatched sample (i.e. comparison with the non-depressed general population), the disparity between individuals with and without depression is greater. While phase 1 was associated with an immediate increase in ED-visits among the general population, phase 2 was not associated with any changes in the unmatched depressed and non-depressed groups. Conclusions. Depression is a risk factor for cannabis-related ED-visits. Cannabis legalisation did not further elevate the risk among individuals diagnosed with depression. 10 Chungah Kim et al.

In order to understand the state and evolution of the entirety of open source software we need to... more In order to understand the state and evolution of the entirety of open source software we need to get a handle on the set of distinct software projects. Most of open source projects presently utilize Git, which is a distributed version control system allowing easy creation of clones and resulting in numerous repositories that are almost entirely based on some parent repository from which they were cloned. Git commits are unlikely to get produce and represent a way to group cloned repositories. We use World of Code infrastructure containing approximately 2B commits and 100M repositories to create and share such a map. We discover that the largest group contains almost 14M repositories most of which are unrelated to each other. As it turns out, the developers can push git object to an arbitrary repository or pull objects from unrelated repositories, thus linking unrelated repositories. To address this, we apply Louvain community detection algorithm to this very large graph consisting of links between commits and projects. The approach successfully reduces the size of the megacluster with the largest group of highly interconnected projects containing under 400K repositories. We expect that the resulting map of related projects as well as tools and methods to handle the very large graph will serve as a reference set for mining software projects and other applications. Further work is needed to determine different types of relationships among projects induced by shared commits and other relationships, for example, by shared source code or similar filenames.

Background and AimsPrevious studies have found that lesbian, gay, and bisexual (LGB) individuals ... more Background and AimsPrevious studies have found that lesbian, gay, and bisexual (LGB) individuals report higher rates of substance use compared to the general population. However, evidence regarding the association between sexual orientation and clinically validated substance use outcomes is limited. We aim to quantify disparities in substance-related acute events (i.e., hospitalizations and deaths for substances including alcohol, cannabis, opioids, narcotics, and/or illicit drugs) across sexual orientations based on health administrative data.MethodsThe study cohort (weighted n=15,406,000) was built from six waves of the Canadian Community Health Survey (2009-14) linked to hospitalization/mortality data. Disparities in substance-related acute events across sexual orientation and gender among Canadian residents aged 15+ were examined using flexible parametric survival analysis.ResultsBisexual women had hazard ratios of 2.46 (95%CI: 1.46-4.15) for any substance-related acute event an...

BMC Public Health

Background Employment conditions may affect individuals’ leisure-time physical activity (LTPA). W... more Background Employment conditions may affect individuals’ leisure-time physical activity (LTPA). We aimed to examine the relationship between changes in working and employment conditions and LTPA among working-age populations in South Korea from 2009 to 2019. Methods A cohort of 6,553 men and 5,124 women aged 19–64 years was analyzed using linear individual-level fixed-effects regressions to examine changes in working and employment conditions with changes in LTPA. Results Reduced working hours, labor union membership, and part-time work were associated with increased LTPA for both sexes. Manual labor and self-reported precarious work were associated with reduced LTPA. The longitudinal relationship between employment conditions and LTPA was clear in men, but less apparent in women. Conclusions Changes in working and employment conditions had longitudinal associations with changes in LTPA among working-age Koreans. Future research should examine changing employment conditions and thei...

American Journal of Psychiatry

PLOS ONE

Background There have been no studies examining how neighbourhood deprivation modifies the effect... more Background There have been no studies examining how neighbourhood deprivation modifies the effects of sexual minority status on suicide-related behaviours (SRB). Sexual minority individuals in deprived areas may face unique challenges and stressors that exacerbate their risk of SRB. This study aims to investigate the association between sexual minority status and clinical SRB, and examine whether the effect of neighbourhood deprivation differs across sexual orientation. Methods A population-representative survey sample (169,090 respondents weighted to represent 8,778,120 individuals; overall participation rate 75%) was linked to administrative health data in Ontario, Canada to measure SRB-related events (emergency department visits, hospitalizations, and deaths) from 2007 to 2017. Neighbourhood-level deprivation was measured using the Ontario Marginalisation index measure of material deprivation at the dissemination area level. Discrete-time survival analysis models, stratified by s...

ObjectiveCannabis use may reduce the effectiveness of antipsychotic medication and treatment adhe... more ObjectiveCannabis use may reduce the effectiveness of antipsychotic medication and treatment adherence in schizophrenia patients. This study examined the impact of cannabis legalization on cannabis-related acute care among schizophrenia patients. MethodsUsing health administrative data in Ontario, 119,848 individuals who were diagnosed with schizophrenia prior to legalization were identified. An interrupted time-series model was used to study the effect of cannabis-related policy on hospitalizations in individuals diagnosed with schizophrenia.ResultsWe found that legalization of cannabis flower and herb sales was associated with an immediate increase in hospitalization by 233.6% (95%CI 1.59-3.414) for men and 216.1% (95%CI 1.59-3.390) for women with schizophrenia. ConclusionsOther jurisdictions seeking to legalize recreational cannabis should consider preventive strategies to reduce unintended consequences among vulnerable patients.

Rural sexual minorities may experience unique stressors due to stigma and a lack of sexual minori... more Rural sexual minorities may experience unique stressors due to stigma and a lack of sexual minority-specific social and health services. We examine whether rural and sexual minority status are associated with suicide-related behaviour (SRB) risks, using a nationally representative survey linked to administrative health data of Ontario individuals from 2007-2017. Our study provides evidence that rural and sexual minority status both independently contribute to an elevated likelihood of SRB; however, sexual orientation did not appear to modify the SRB risk by rurality. Evaluations of interventions to reduce SRB in both rural and sexual minority populations are required.

A tropical variety is a weighted polyhedral complex whose maximal dimensional cells are pure dime... more A tropical variety is a weighted polyhedral complex whose maximal dimensional cells are pure dimensional, rational, connected, and balanced weighted around every vertex. It is known that every irreducible algebraic variety can be tropicalized, that is, there is a way one can derive a tropical variety from an algebraic one. However, there exist tropical varieties that are not the tropicalization of algebraic varieties. The goal of this work is to answer whether a given tropical curve (a 1−dimensional tropical variety) in R is the tropicalization of an algebraic curve in R.

BackgroundThere have been no studies examining how neighbourhood deprivation modifies the effects... more BackgroundThere have been no studies examining how neighbourhood deprivation modifies the effects of sexual minority status on suicide-related behaviours (SRB). Sexual minority individuals in deprived areas may face unique challenges and stressors that exacerbate their risk of SRB. This study aims to investigate the association between sexual minority status and clinical SRB, and examine whether the effect of neighbourhood deprivation differs across sexual orientation. MethodsA population-representative survey sample (weighted n= 8,778,120) was linked to administrative health data in Ontario, Canada to measure SRB-related events (emergency department visits, hospitalizations, and deaths) from 2007 to 2017. Neighbourhood-level deprivation was measured using the Ontario Marginalisation index measure of material deprivation at the dissemination area level. Discrete-time survival analysis models, stratified by sex, tested the effects of neighbourhood deprivation and sexual minority stat...

SSRN Electronic Journal

Objective: To quantify suicide-related behaviour (SRB) leading to acute care or deaths across het... more Objective: To quantify suicide-related behaviour (SRB) leading to acute care or deaths across heterosexual, homosexual, and bisexual individuals using population-representative sample and health administrative data. Methods: We linked data from a population-based survey (n=123,995) to health administrative data (2002-2019), and examined differences in time-to-SRB events across sexual orientations using Cox proportional hazards regression. Results: The crude incidence rates for heterosexuals was 224.67 SRB events/100,000 person-years, while the rates for homosexuals was 664.74, and bisexuals was 5911.88. In fully adjusted (gender-combined) models, bisexual individuals were 2.98 times (95% CI, 2.08-4.27) more likely to have a SRB event, and gay men and lesbians were 2.10 times (95% CI, 1.18-3.71) more likely, compared to heterosexual individuals. Conclusions: In a large, population-based sample of Ontario residents using clinically relevant outcomes, LGB individuals were at elevated risk of SRB events. Increased education among psychiatric professionals is needed to improve awareness and sensitivity towards the elevated risk of LGB SRB events. Further funding and research on interventions to reduce sexual minority SRB is required.

Proceedings of the 17th International Conference on Mining Software Repositories, 2020