Gabriela Rosu - Academia.edu (original) (raw)

Papers by Gabriela Rosu

Research paper thumbnail of Aeration Lagoon as Advanced Solution for Leachate Epuration-A Study Case in Glina Purge Unit

Leachate is a liquid waste product of the processes in solid waste landfills with meteoric waters... more Leachate is a liquid waste product of the processes in solid waste landfills with meteoric waters seeping. A number of substances are dissolved by washing with meteoric water and other substances resulting from the processes of fermentation of organic waste components. Leachate treatment is essential to reduce mainly the organic and nitrogen content in the leachate. The initial solution applied to the purge unit-Glina was a biologic reverse osmosis in two steps (osmosis layout). An aeration lagoon has been designed and proposed to be installed as pilot in Glina. The leachate provides the food for the bacteria and the aeration system provides the oxygen. The results are suggesting that this lagoon technology can be economic to install and simple to run.

Research paper thumbnail of Influence of Environmental Conditions on Leachate Bioscrubbers

The study targeted the establishment of optimal conditions for biological treatment of leachate f... more The study targeted the establishment of optimal conditions for biological treatment of leachate from Glina landfill waste. A change in the composition of leachate was analysed in correlation with temperature, precipitation and biodegradable material to highlight the work of microorganisms in various environmental conditions. The experimental results have shown that the highest efficiency has been registered over the temperature range of 10-25oC, while microbiological activity was not observed in the aeration lagoon at negative air temperature. The higher content in biodegradable waste (obtained by separating plastics, paper, metal and glass) had a positive influence on biological purge expressed by decreasing the nitrates, nitrites, ammonia content and biological oxygen demand between 12% and 28%.

Research paper thumbnail of the Economic Impact of Total Knee Replacement in Patients with Haemophilia and Inhibitors: Analysis from a Uk Payer Perspective : p087

Research paper thumbnail of The potential correlation between patient-reported symptoms and the use of additional haemostatic medication for joint bleeding in haemophilia patients with inhibitors

Blood Coagulation & Fibrinolysis, 2017

Haemophilia treatment guidelines advocate early homebased treatment of acute bleeds. In the ADEPT... more Haemophilia treatment guidelines advocate early homebased treatment of acute bleeds. In the ADEPT2 trial, data were collected on the home treatment of bleeds with recombinant activated factor VII (rFVIIa) in haemophilia patients with inhibitors and self-reported bleeding-related symptoms. A total of 93% of all bleeds, and 91.5% of joint bleeds, were treated successfully with one to three doses of 90 mg/kg rFVIIa. However, some patients self-administered additional haemostatic medication (AHM) up to 48 h after the first rFVIIa treatment. The aim of this trial was to investigate the relationship between patient-reported symptoms, time to treatment initiation, and the use of AHM. A post hoc analysis was conducted on 177 joint bleeds and the patient-reported categorical symptoms of pain, swelling, mobility, tingling, and warmth, and the pain visual analogue scale (VAS) score. Analyses were descriptive and used logistic regression modelling. Complete symptom data were available for 141, 136, and 129 joint bleeds at 0 or 1, 3, and 6 h, respectively. Pain and pain VAS assessments were the best predictors of AHM use. Patients who selfadministered AHM had higher mean pain VAS scores at each time point; both pain and pain VAS scores declined over time. Time to treatment initiation was an independent predictor for AHM use. Higher initial pain scores and longer time to treatment were the best predictors for administration of AHM. The observation that some patients chose to self-infuse in the face of declining levels of pain warrants further study to better understand the reasons behind patient decision-making. Blood Coagul Fibrinolysis

Research paper thumbnail of Treatment outcomes, quality of life, and impact of hemophilia on young adults (aged 18-30 years) with hemophilia

American journal of hematology, 2015

The Hemophilia Experiences, Results and Opportunities (HERO) initiative assessed psychosocial iss... more The Hemophilia Experiences, Results and Opportunities (HERO) initiative assessed psychosocial issues reported by people with moderate to severe hemophilia and was led by a multidisciplinary international advisory board. This analysis reports data from young adult respondents (aged 18-30 years), including both US and overall global (including US respondents) results, and investigates treatment outcomes, quality of life, and impacts of hemophilia on relationships. More young adults in HERO received prophylaxis than on-demand treatment, although a majority reported not using factor products exactly as prescribed, and 50% of global respondents and 26% of US respondents reported issues with access to factor replacement therapy in the previous 5 years. Many young adults with hemophilia reported comorbidities, including bone/skeletal arthritis, chronic pain, and viral infections, and nearly half of young adults reported anxiety/depression. Most reported pain interference with daily activit...

Research paper thumbnail of Recombinant activated factor VII in the treatment of massive bleeding in cardiac surgical patients

European Journal of Anaesthesiology, 2006

Research paper thumbnail of Radial Correlation in Atoms

Research paper thumbnail of Aeration Lagoon as Advanced Solution for Leachate Epuration-A Study Case in Glina Purge Unit

Leachate is a liquid waste product of the processes in solid waste landfills with meteoric waters... more Leachate is a liquid waste product of the processes in solid waste landfills with meteoric waters seeping. A number of substances are dissolved by washing with meteoric water and other substances resulting from the processes of fermentation of organic waste components. Leachate treatment is essential to reduce mainly the organic and nitrogen content in the leachate. The initial solution applied to the purge unit-Glina was a biologic reverse osmosis in two steps (osmosis layout). An aeration lagoon has been designed and proposed to be installed as pilot in Glina. The leachate provides the food for the bacteria and the aeration system provides the oxygen. The results are suggesting that this lagoon technology can be economic to install and simple to run.

Research paper thumbnail of Influence of Environmental Conditions on Leachate Bioscrubbers

The study targeted the establishment of optimal conditions for biological treatment of leachate f... more The study targeted the establishment of optimal conditions for biological treatment of leachate from Glina landfill waste. A change in the composition of leachate was analysed in correlation with temperature, precipitation and biodegradable material to highlight the work of microorganisms in various environmental conditions. The experimental results have shown that the highest efficiency has been registered over the temperature range of 10-25oC, while microbiological activity was not observed in the aeration lagoon at negative air temperature. The higher content in biodegradable waste (obtained by separating plastics, paper, metal and glass) had a positive influence on biological purge expressed by decreasing the nitrates, nitrites, ammonia content and biological oxygen demand between 12% and 28%.

Research paper thumbnail of the Economic Impact of Total Knee Replacement in Patients with Haemophilia and Inhibitors: Analysis from a Uk Payer Perspective : p087

Research paper thumbnail of The potential correlation between patient-reported symptoms and the use of additional haemostatic medication for joint bleeding in haemophilia patients with inhibitors

Blood Coagulation & Fibrinolysis, 2017

Haemophilia treatment guidelines advocate early homebased treatment of acute bleeds. In the ADEPT... more Haemophilia treatment guidelines advocate early homebased treatment of acute bleeds. In the ADEPT2 trial, data were collected on the home treatment of bleeds with recombinant activated factor VII (rFVIIa) in haemophilia patients with inhibitors and self-reported bleeding-related symptoms. A total of 93% of all bleeds, and 91.5% of joint bleeds, were treated successfully with one to three doses of 90 mg/kg rFVIIa. However, some patients self-administered additional haemostatic medication (AHM) up to 48 h after the first rFVIIa treatment. The aim of this trial was to investigate the relationship between patient-reported symptoms, time to treatment initiation, and the use of AHM. A post hoc analysis was conducted on 177 joint bleeds and the patient-reported categorical symptoms of pain, swelling, mobility, tingling, and warmth, and the pain visual analogue scale (VAS) score. Analyses were descriptive and used logistic regression modelling. Complete symptom data were available for 141, 136, and 129 joint bleeds at 0 or 1, 3, and 6 h, respectively. Pain and pain VAS assessments were the best predictors of AHM use. Patients who selfadministered AHM had higher mean pain VAS scores at each time point; both pain and pain VAS scores declined over time. Time to treatment initiation was an independent predictor for AHM use. Higher initial pain scores and longer time to treatment were the best predictors for administration of AHM. The observation that some patients chose to self-infuse in the face of declining levels of pain warrants further study to better understand the reasons behind patient decision-making. Blood Coagul Fibrinolysis

Research paper thumbnail of Treatment outcomes, quality of life, and impact of hemophilia on young adults (aged 18-30 years) with hemophilia

American journal of hematology, 2015

The Hemophilia Experiences, Results and Opportunities (HERO) initiative assessed psychosocial iss... more The Hemophilia Experiences, Results and Opportunities (HERO) initiative assessed psychosocial issues reported by people with moderate to severe hemophilia and was led by a multidisciplinary international advisory board. This analysis reports data from young adult respondents (aged 18-30 years), including both US and overall global (including US respondents) results, and investigates treatment outcomes, quality of life, and impacts of hemophilia on relationships. More young adults in HERO received prophylaxis than on-demand treatment, although a majority reported not using factor products exactly as prescribed, and 50% of global respondents and 26% of US respondents reported issues with access to factor replacement therapy in the previous 5 years. Many young adults with hemophilia reported comorbidities, including bone/skeletal arthritis, chronic pain, and viral infections, and nearly half of young adults reported anxiety/depression. Most reported pain interference with daily activit...

Research paper thumbnail of Recombinant activated factor VII in the treatment of massive bleeding in cardiac surgical patients

European Journal of Anaesthesiology, 2006

Research paper thumbnail of Radial Correlation in Atoms