Gang Liu - Academia.edu (original) (raw)

Papers by Gang Liu

Coastal Engineering 2000, 2001

A new set of highly accurate Boussinesq-type equations are presented. The equations are formulate... more A new set of highly accurate Boussinesq-type equations are presented. The equations are formulated in six variables, counting vectors as one: The surface elevation, the horizontal gradient of the velocity potential at the free surface, the horizontal and vertical velocities at the free surface and the horizontal and vertical velocities at an arbitrary z-level. The arbitrary z-level is determined by optimizing the vertical distribution of the horizontal and vertical velocity components compared to linear fully dispersive wave theory. A Stokes type analysis is performed and the new formulation is found to retain high accuracy in the linear and nonlinear characteristics for wave numbers as high as kh=30. A numerical model is developed in one horizontal dimension and results are presented for the case of a highly nonlinear solitary wave propagating over a constant depth. The numerical results are shown to be in excellent agreement with exact solutions.

Ocean Wave Measurement and Analysis (2001), 2002

2009 3rd International Conference on Bioinformatics and Biomedical Engineering, 2009

Calcium phosphate cement (CPC) sets in situ to form hydroxyapatite and is highly promising for a ... more Calcium phosphate cement (CPC) sets in situ to form hydroxyapatite and is highly promising for a wide range of clinical applications. However, its low strength limits its use to only non-stress applications, and its lack of macroporosity hinders cell infiltration, bone ingrowth and implant fixation. The aim of this study was to develop strong and macroporous CPC scaffolds by incorporating

AIM: To explore a safe and efficient strategy of tumor therapy using anti-angiogenetic agents. ME... more AIM: To explore a safe and efficient strategy of tumor therapy using anti-angiogenetic agents. METHODS: Endostatin gene with a signal sequence of human IgG γ chain was amplified by PCR and cloned into pVAX1 plasmid which was the only vector authorized by FDA in clinical trial to construct a recombinant plasmid named as pVAX-sEN. The recombinant plasmid was detected with

The 6th IEEE/ACM International Workshop on Grid Computing, 2005., 2005

The scale, heterogeneity and dynamism of Grid applications and environments require Grid applicat... more The scale, heterogeneity and dynamism of Grid applications and environments require Grid applications to be self-managing or autonomic. This paper presents the Accord autonomic services architecture that addresses this requirement. Accord enables service and application behaviors and their interactions to be dynamically specified and adapted using high-level rules, based on current application requirements, state and execution context. The design, implementation and evaluation of Accord are presented. An autonomic data streaming application is used to illustrate the self-managing behaviors enabled by Accord.

This paper describes a short-pulse ultraviolet laser probe with multistage wavelength converters ... more This paper describes a short-pulse ultraviolet laser probe with multistage wavelength converters and nonlinear optical compression. Through fourth harmonic generation and double stage backward Raman scattering, pulses as short as 15 ps at 308 nm with more than 1 mJ energy and uniform beam pattern are successfully obtained. The whole probe system shows precise timing and good stability.

Biochemical and Biophysical Research Communications, 2009

Fatty acid desaturases play important role in plant responses to abiotic stresses including cold,... more Fatty acid desaturases play important role in plant responses to abiotic stresses including cold, high temperature, drought, and osmotic stress. In this work, we provide the evidence that Fad6, a chloroplast desaturase, is required for salt tolerance during the early seedling development of Arabidopsis. Expression of Fad6 was responsive to salt and osmotic stress. Compared with the wild-type plants, the

International Conference on Computer Science and Service System, 2011

With the development of the modern society, Finance and Technology have become the important fact... more With the development of the modern society, Finance and Technology have become the important factor to the social productivity, They have influenced each other: on the one hand, the development of science and technology relies on the back of finance because of the characters of high risk of High-Technology Industry; on the other hand, the improvement of finance service itself is based on the technology innovation. This paper describes the development of finance and technology in Wuhan Megalopolis firstly, by the regression analysis, and suggests that it is significant to construct the good operation mechanism between finance and technology in Wuhan Megalopolis to promote Hubei's economic development.

We have previously shown that members of the ELR ؉ CXC chemokine family, including IL-8; growth-r... more We have previously shown that members of the ELR ؉ CXC chemokine family, including IL-8; growth-related oncogenes ␣, ␤, and ␥; granulocyte chemotactic protein 2; and epithelial neutrophil-activating protein-78, can mediate angiogenesis in the absence of preceding inflammation. To date, the receptor on endothelial cells responsible for chemotaxis and neovascularization mediated by these ELR ؉ CXC chemokines has not been determined. Because all ELR ؉ CXC chemokines bind to CXC chemokine receptor 2 (CXCR2), we hypothesized that CXCR2 is the putative receptor for ELR ؉ CXC chemokine-mediated angiogenesis. To test this postulate, we first determined whether cultured human microvascular endothelial cells expressed CXCR2. CXCR2 was detected in human microvascular endothelial cells at the protein level by both Western blot analysis and immunohistochemistry using polyclonal Abs specific for human CXCR2. To determine whether CXCR2 played a functional role in angiogenesis, we determined whether this receptor was involved in endothelial cell chemotaxis. We found that microvascular endothelial cell chemotaxis in response to ELR ؉ CXC chemokines was inhibited by anti-CXCR2 Abs. In addition, endothelial cell chemotaxis in response to ELR ؉ CXC chemokines was sensitive to pertussis toxin, suggesting a role for G protein-linked receptor mechanisms in this biological response. The importance of CXCR2 in mediating ELR ؉ CXC chemokine-induced angiogenesis in vivo was also demonstrated by the lack of angiogenic activity induced by ELR ؉ CXC chemokines in the presence of neutralizing Abs to CXCR2 in the rat corneal micropocket assay, or in the corneas of CXCR2 ؊/؊ mice. We thus conclude that CXCR2 is the receptor responsible for ELR ؉ CXC chemokine-mediated angiogenesis.

Cell Biology International, 2008

obtain the distribution of flow field and wall shear stress. Rabbits were sacrificed and relative... more obtain the distribution of flow field and wall shear stress. Rabbits were sacrificed and relative arteries were obtained at 4 weeks. Plasma total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) were determined by commercially enzymatic methods. The pathological slides were prepared and stained for optical microscopic observation. The content of cholesterol in arteries wall was assayed with High Performance Liquid Chromatography (HPLC). Immunohistochemistry staining was used to detect the expression in atherosclerotic lesions. Results showed that there was a low shear stress region (0e0.3 Pa) at distal of ring. At the end of 4 weeks, plasma total cholesterol, HDL cholesterol and triglyceride had no obviously changed in rabbits. HE staining showed that there were obvious atherosclerosis lesions in low shear stress field. There was obvious lipid deposition in atherosclerosis lesions. CXCR4 was highly expressed in atherosclerotic plaque without expression in control. These data suggest that CXCR4 may play important roles in atherosclerosis formation and development induced by low shear stress. The authors gratefully acknowledge the financial support from the National Natural Sciences Foundation of China (30700325) and Hunan Provincial Natural Sciences Foundation of China (06jj50051).

For controlling anal incontinence, the new artificial anal sphincter system (AASS) with sensor fe... more For controlling anal incontinence, the new artificial anal sphincter system (AASS) with sensor feedback based on transcutaneous energy transmission is developed. The implanted components are powered by a transcutaneous transformer, which is formed from a pair of concave/convex cores. This design minimizes lateral motion of the external core. A Class-E power amplifier is chosen to drive the transmitter coil due

Molecular medicine reports, Jan 25, 2015

Dilated cardiomyopathy (DCM) is the most common form of primary myocardial disease. It is the mos... more Dilated cardiomyopathy (DCM) is the most common form of primary myocardial disease. It is the most common cause of chronic congestive heart failure and the most frequent reason for heart transplantation in young adults. There is increasing evidence demonstrating that genetic defects are involved in the pathogenesis of idiopathic DCM. Recent studies have shown that genetically defective LRRC10 predisposes animals to DCM. However, the association of LRRC10 with DCM in humans has not been reported. In the current study, the whole coding region and flanking splice junction sites of the LRRC10 gene were sequenced in 220 unrelated patients with idiopathic DCM. The available relatives of the index patients harboring identified mutations and 200 unrelated ethnically matched healthy individuals used as controls were also genotyped for LRRC10. The functional effect of the LRRC10 mutations was analyzed in silico. As a result, two novel heterozygous LRRC10 mutations, p.L41V and p.L163I, were id...

The Spatial Decision Support System (SDSS), as an emerging field of science and technology, is co... more The Spatial Decision Support System (SDSS), as an emerging field of science and technology, is combined by Geographic Information System (GIS) and decision support system (DSS). Nowadays, more and more attentions have been paid to the technology of SDSS, and the construction of geographic database in SDSS has been a hot-spot for many years. One of the commonly used methods

BMJ open, Jan 8, 2015

To investigate the associations between plasma levels of pentraxins 3 (PTX3) and C reactive prote... more To investigate the associations between plasma levels of pentraxins 3 (PTX3) and C reactive protein (CRP) and the severity of coronary artery lesions. 60 patients with coronary heart disease (CHD) who underwent coronary angiography (CAG) in our hospital were included. Plasma was collected during CAG. The coronary Gensini score was used to evaluate the severity of coronary artery lesions. Associations between Gensini scores and plasma levels of PTX3 and CRP were analysed. Patients with estimated glomerular filtration rate <60 mL/min/1.73 m(2) were included in the chronic renal dysfunction subgroup. A linear correlation was observed between PTX3 and the Gensini score (r=0.513, p<0.001). One-way analysis of variance showed that PTX3 levels were significantly higher in patients with Gensini scores >90 compared with patients with scores of 46-90 or…

IEEE Global Telecommunications Conference, 2004. GLOBECOM '04.

In this research, we study the self-maintenance scheduling problem in next generation wireless ne... more In this research, we study the self-maintenance scheduling problem in next generation wireless networks, with the consideration of resource maintenance constraints and resource conflicting constraints. We propose a linear programming (ILP) model and two heuristic algorithms, and evaluate their effectiveness and time complexity via analysis and simulations. Our results show that all of the proposed approaches can effectively schedule the requests within a reasonable period of time, but with different suitable scenarios. The ILP approach is effective when the number of requests is large and yields close-to-optimal results; the RC-Cliques-RM algorithm is suitable at the presence of many constraints; while the RC-RM-Cliques algorithm can scale to large size networks at the expense of reduced accuracy. It is anticipated that the proposed scheduling algorithms will be generally applicable to various mobile wireless networks where self-maintenance is needed.

Journal of Cardiothoracic Surgery, 2015

The Publisher and Editor regretfully retract this article [1] because the peer-review process was... more The Publisher and Editor regretfully retract this article [1] because the peer-review process was inappropriately influenced and compromised. As a result, the scientific integrity of the article cannot be guaranteed. A systematic and detailed investigation suggests that a third party was involved in supplying fabricated details of potential peer reviewers for a large number of manuscripts submitted to different journals. In accordance with recommendations from COPE we have retracted all affected published articles, including this one. It was not possible to determine beyond doubt that the authors of this particular article were aware of any third party attempts to manipulate peer review of their manuscript.

40th Annual Simulation Symposium (ANSS'07), 2007

The paper describes the creation of a street driving simulator for virtual tour. The simulator us... more The paper describes the creation of a street driving simulator for virtual tour. The simulator uses real-time interactive virtual environment technology to immerse visitors in a 3D reconstruction of some main streets of Wuhan. Visitors can sit in and operate the simulator to tour fifty kilometer long streets of the city modeled in high-resolution 3D graphics. In this project supported

Cancer research, Jan 15, 1999

Cyclooxygenase-2 (COX-2) inhibitors reduce angiogenic responses to a variety of stimuli, suggesti... more Cyclooxygenase-2 (COX-2) inhibitors reduce angiogenic responses to a variety of stimuli, suggesting that products of COX-2 may mediate critical steps. Here, we show that thromboxane A2 (TXA2) is one of several eicosanoid products generated by activated human microvascular endothelial cells. Selective COX-2 antagonists inhibit TXA2 production, endothelial migration, and fibroblast growth factor-induced corneal angiogenesis. Endothelial migration and corneal angiogenesis are similarly inhibited by a TXA2 receptor antagonist, SQ29548. A TXA2 agonist, U46619, reconstitutes both migration and angiogenesis responses under COX-2-inhibited conditions. These findings identify TXA2 as a COX-2 product that functions as a critical intermediary of angiogenesis.

Key Engineering Materials, 2007

With an aim to achieve a breakthrough the choke point in research on system design, to achieve th... more With an aim to achieve a breakthrough the choke point in research on system design, to achieve the transforming in multiple fields of view, the approaching to system efficacy limit in theory and improving smartness, pure diffractive optical system is chosen. The top idea and main strategy is developed. Some correlative model is established. In optimized design, global optimization algorithm is used to achieve wider spectrum range, multi field view, lower distortion and appropriate MTF. A kind of result works mainly in 3~5%m and 8~12%m with high ratio of more than 20:1 is evaluated. And this integrated multi-sensor electro-optical system satisfies the applied requirements o some criteria, such as Modulation Transfer Function (MTF), Spot Diagram (RMS) and Point Spread Function (PSF) etc., and achieves remarkable advantages in volume, weight, system efficiency and so on.