Gavin Lee - Academia.edu (original) (raw)

Papers by Gavin Lee

Ethos: Official Publication of the Law Society of the Australian Capital Territory, Sep 1, 2015

Routledge Handbook of Corrections in the United States, 2017

2018. In Gavin Lee ed., Rethinking Difference in Gender, Sexuality, and Popular Music: Theory and... more 2018. In Gavin Lee ed., Rethinking Difference in Gender, Sexuality, and Popular Music: Theory and Politics of Ambiguity (Routledge).

The Journal of Rheumatology, 2019

Objective.To identify and synthesize the best available evidence on the application of musculoske... more Objective.To identify and synthesize the best available evidence on the application of musculoskeletal (MSK) ultrasound (US) in patients with systemic lupus erythematosus (SLE) and to present the measurement properties of US in different elementary lesions and pathologies.Methods.A systematic literature search of PubMed, Embase, and the Cochrane Library was performed. Original articles were included that were published in English between August 1, 2014, and December 31, 2018, reporting US, Doppler, synovitis, joint effusion, bone erosion, tenosynovitis, and enthesitis in patients with SLE. Data extraction focused on the definition and quantification of US-detected synovitis, joint effusion, bone erosion, tenosynovitis, enthesitis, and the measurement properties of US according to the OMERACT Filter 2.1 instruments selection.Results.Of the 143 identified articles, 15 were included. Most articles were cross-sectional studies (14/15, 93%). The majority of the studies used the OMERACT d...

Agromining: Farming for Metals, 2020

Agromining: Farming for Metals, 2017

The identification and use of hyperaccumulator plants in mining projects has been recognised as a... more The identification and use of hyperaccumulator plants in mining projects has been recognised as an important component part of mine planning at several sites around the world. Indeed, mine planning that includes hyperaccumulator plants requires operators to maximize the biological resources of a site by discovering and utilizing these unusual plant species at the early planning stages. These locally adapted hyperaccumulator species can then be used for rehabilitation in and around the mine area, or be utilized for their potential to extract ecocatalysts and metals. Such opportunities should be more widely explored so that these unique plants can become an integrated and valuable part of the mining process. This chapter concentrates on the experiences of integrating hyperaccumulating plants into mine rehabilitation projects in Indonesia and New Caledonia, in order to highlight some of the opportunities and challenges encountered when attempting to incorporate these species into the mining cycle.

arXiv (Cornell University), Oct 24, 2020

Identifying individuals who are at high risk of cancer due to inherited germline mutations is cri... more Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models to identify these individuals focus on specific syndromes by including family and personal history for a small number of cancers. Recent evidence from multi-gene panel testing has shown that many syndromes once thought to be distinct are overlapping, motivating the development of models that incorporate family history information on several cancers and predict mutations for more comprehensive panels of genes. Once such class of models are Mendelian risk prediction models, which use family history information and Mendelian laws of inheritance to estimate the probability of carrying genetic mutations, as well as future risk of developing associated cancers. To flexibly model the complexity of many cancer-mutation associations, we present a new software tool called PanelPRO, an R package that extends the previously developed BayesMendel R package to user-selected lists of susceptibility genes and associated cancers. The model identifies individuals at an increased risk of carrying cancer susceptibility gene mutations and predicts future risk of developing hereditary cancers associated with those genes. Additional functionalities adjust for prophylactic interventions, known genetic testing results, and risk modifiers such as race and ancestry. The package comes with a customizable database with default parameter values estimated from published studies. This includes estimates of cancer penetrances, allele frequencies, and risk ratios for specific interventions, all stratified on different sets of demographic factors. The PanelPRO package is open-source and provides a fast and flexible back-end for multi-gene, multi-cancer risk modeling with pedigree data. The software enables the identification of high-risk individuals, which will have an impact on personalized prevention strategies for cancer and individualized decision making about genetic testing.

Proceedings of the National Academy of Sciences

Since the beginning of the COVID-19 pandemic, many dashboards have emerged as useful tools to mon... more Since the beginning of the COVID-19 pandemic, many dashboards have emerged as useful tools to monitor its evolution, inform the public, and assist governments in decision-making. Here, we present a globally applicable method, integrated in a daily updated dashboard that provides an estimate of the trend in the evolution of the number of cases and deaths from reported data of more than 200 countries and territories, as well as 7-d forecasts. One of the significant difficulties in managing a quickly propagating epidemic is that the details of the dynamic needed to forecast its evolution are obscured by the delays in the identification of cases and deaths and by irregular reporting. Our forecasting methodology substantially relies on estimating the underlying trend in the observed time series using robust seasonal trend decomposition techniques. This allows us to obtain forecasts with simple yet effective extrapolation methods in linear or log scale. We present the results of an assess...

, Lisa). The course is intended to provide historical overview of the field of psychology, includ... more , Lisa). The course is intended to provide historical overview of the field of psychology, including its conceptual situation in broad traditions of thought and as it has developed in its "mainstream" trajectories as a distinct discipline. The main purpose of the course is to reflect on and critically assess standard accounts of psychology's history, which will afford assessment of its future. (See https://apps.westga.edu/catalog/) Request: Add Rationale: Replaces PSYC 8003. Opens course to MA students.

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science... more A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in the Department of Criminal Justice and Legal Studies in the College of Health and Public Affairs at the University of Central Florida Orlando, Florida ... This thesis tests the three ...

eLife

Nature Communications

Disease modelling has had considerable policy impact during the ongoing COVID-19 pandemic, and it... more Disease modelling has had considerable policy impact during the ongoing COVID-19 pandemic, and it is increasingly acknowledged that combining multiple models can improve the reliability of outputs. Here we report insights from ten weeks of collaborative short-term forecasting of COVID-19 in Germany and Poland (12 October–19 December 2020). The study period covers the onset of the second wave in both countries, with tightening non-pharmaceutical interventions (NPIs) and subsequently a decay (Poland) or plateau and renewed increase (Germany) in reported cases. Thirteen independent teams provided probabilistic real-time forecasts of COVID-19 cases and deaths. These were reported for lead times of one to four weeks, with evaluation focused on one- and two-week horizons, which are less affected by changing NPIs. Heterogeneity between forecasts was considerable both in terms of point predictions and forecast spread. Ensemble forecasts showed good relative performance, in particular in ter...

Journal of Geochemical Exploration