Gholamreza Bayazian - Academia.edu (original) (raw)

Papers by Gholamreza Bayazian

Research paper thumbnail of Relationship Between Serum Vitamin D Levels and Serous Otitis Media in Children with Adenoid Hypertrophy Based on Age

Thrita, Jun 1, 2020

Background: Serous Otitis Media (SOM) is one of the most common diseases of children that can lea... more Background: Serous Otitis Media (SOM) is one of the most common diseases of children that can lead to hearing loss and imbalance. Recently, the role of vitamin D has been identified in strengthening and regulating the immune system. Moreover, vitamin D supplementation has been recognized to improve the immune response against upper respiratory infection and pathogen overgrowth. Methods: A cross-sectional study was performed on 89 children aged 1-15 years with adenoid hypertrophy who met the inclusion criteria. The serum vitamin D level was compared between the two groups of children with and without SOM. Results: The mean age of the target children was 69.57 ± 25.65 months. The mean serum vitamin D level was 23.86 ± 12.7 in all patients. The mean serum vitamin D level was 24.7 ± 13.1 and 22.9 ± 12.2 in patients with and without SOM (based on tympanometry), respectively, yet the difference was not statistically significant. However, the difference was significant between the two groups of children with the age of < 84 months and > 84 months (P = 0.05). Conclusions: The role of vitamin D was identified in increasing the incidence of SOM in children older than 84 months with adenoid hypertrophy. In older children, the timely diagnosis and treatment of vitamin D deficiency can prevent severe SOM complications, which can save a lot of costs for families and the health system.

Research paper thumbnail of A Systematic Review on Machine Learning Techniques for Early Detection of Mental, Neurological and Laryngeal Disorders Using Patient’s Speech

Electronics

There is a substantial unmet need to diagnose speech-related disorders effectively. Machine learn... more There is a substantial unmet need to diagnose speech-related disorders effectively. Machine learning (ML), as an area of artificial intelligence (AI), enables researchers, physicians, and patients to solve these issues. The purpose of this study was to categorize and compare machine learning methods in the diagnosis of speech-based diseases. In this systematic review, a comprehensive search for publications was conducted on the Scopus, Web of Science, PubMed, IEEE and Cochrane databases from 2002–2022. From 533 search results, 48 articles were selected based on the eligibility criteria. Our findings suggest that the diagnosing of speech-based diseases using speech signals depends on culture, language and content of speech, gender, age, accent and many other factors. The use of machine-learning models on speech sounds is a promising pathway towards improving speech-based disease diagnosis and treatments in line with preventive and personalized medicine.

Research paper thumbnail of Allergy status in children with adenoid hypertrophy with and without serous otitis media

Immunopathologia Persa

Introduction: Serous otitis media (SOM) is one of the most common diseases of children which can ... more Introduction: Serous otitis media (SOM) is one of the most common diseases of children which can lead to hearing loss and imbalance in many cases. Objective: To evaluate the relationship between allergy status and SOM in children with adenoid hypertrophy and whether affected by age group. Materials and Methods: This cross-sectional study was conducted on 103 children aged 1-15 years with grade III or IV adenoid hypertrophy (± SOM) who referred to ear, nose, and throat (ENT) clinic. Additionally, children were divided into two subgroups based on age category of below and above seven years. The allergy status in children with and without SOM was compared by measuring the total immunoglobulin E (IgE) level, serum eosinophil level and skin prick test (SPT). Results: There was no difference in prevalence of mean absolute eosinophil count (127.3 versus 141.3 eosinophils/ µL, respectively) (P=0.63), mean total IgE level (68.2 versus 140 IU/L, respectively; P=0.119) and positive SPT results...

Research paper thumbnail of Development of a mobile application for self-care of patients with cleft lip and palate

Razi Journal of Medical Sciences, Aug 10, 2021

Research paper thumbnail of Evaluation of adenoid tissue culture according to biofilm grade and annual rate of upper respiratory tract infection in children with upper airway obstruction

Razi Journal of Medical Sciences, Jun 10, 2020

Research paper thumbnail of Designing and Developing a Self-Care Application for Post-Laryngectomy Surgery

Journal of Health and Biomedical Informatics, Jun 10, 2021

Research paper thumbnail of Serum Level of Interleukin-6 in Patients with Oral Tongue

2 The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and nec... more 2 The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to

Research paper thumbnail of Root Cause Analysis of Falling out of bed in one of the Pediatric Hospitals in Tehran in 2019-2020

Health Monitor Journal of the Iranian Institute for Health Sciences Research, 2021

Objective (s): Children are one of the most vulnerable groups in falls from hospital beds, becaus... more Objective (s): Children are one of the most vulnerable groups in falls from hospital beds, because usually this might cause head injurie. There are limited researches to prevent children from falling. Therefore, this study was performed to analyze the roots cause factors affecting the fall in children. Methods: This was a cross-sectional study. First the adverse events were measured using a monthly error recording form, then the root cause analysis of the problem was performed in six steps, problem identification, team formation, preparation of initial information and final map, identification of causes and drawing tables, identification of solutions and implementation and assessment of solutions. Results: Lack of effective training of patient companions, old hospital beds, short, and long distance between bed railings, training of nurses, and controlling of the restless children were obtained as a root causes based on futuristic barrier analysis. The solutions were identified and implemented and the comparison of statistics before and after the implementation of the strategies showed that the rate of falling from the bed in the third quarter of the year has reached to zero percent. Conclusion: Educating the patient companions about the keeping of the bed railings high and not leaving the child can have a great impact on reducing falls. Also, standardizing hospital beds, providing fall prevention guidelines for nurses, training the effective communication skills, and identifying high-risk children can help to reduce falls and injuries.

Research paper thumbnail of A Bilateral Tessier Number 4 and 5 Facial Cleft and Surgical Strategy: A Case Report

Iranian Journal of Otorhinolaryngology, 2013

Introduction: Tessier facial cleft is among the rarest facial clefts reported in literatures and ... more Introduction: Tessier facial cleft is among the rarest facial clefts reported in literatures and there are many issues arguing about its multidisciplinary repairing techniques. Tessier number 4 and 5 are extremely rare facial anomalies. There are few literatures describing these clefts and their surgical modalities. Number 5 Tessier cleft begins medial to oral commissure in the upper lip and extends superiorly as a groove through the cheek and ends at the middle third of lower eyelid. Bonny involvement consists of alveolar ridge, maxillary bone lateral to infra orbital foramen and orbits lower rim and floor. Number 4 Tessier facial cleft begins between cupid bow and oral commissure; skirting the nose and pass through cheek and lateral to lacrimal duct. Bonny involvement consists of alveolar ridge, maxillary bone medial to infra orbital foramen and orbital rim and floor. Case Report: This paper represents a patient with bilateral number 4 and 5 Tessier cleft lip with unilateral compl...

Research paper thumbnail of Serum Level of Interleukin-6 in Patients with Oral Tongue Squamous cell Carcinoma

Iranian Journal of Otorhinolaryngology, 2015

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the ... more Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum levels of interleukin-6 in patients with oral tongue SCC. Materials and Methods: In a cross-sectional study, 17 patients with oral tongue SCC were compared with the same number of age- and gender-matched healthy subjects. Serum IL-6 level fluctuation was determined using an immunological technique, before detecting its possible association with the subjects’ age, gender, drinking and smoking history, cancer site, and disease severity. Results: The intensity of serum IL-6 in patients with oral tongue SCC was statistically significantly higher than that in healthy subjects (P<0.001). Serum IL-6...

Research paper thumbnail of Spontaneous Adenoid Hemorrhage Mimicking Upper GastrointestinalBleeding

Otolaryngology online journal, 2017

Adenoid hypertrophy, a common disorder in pediatric population can present as a variety of sympto... more Adenoid hypertrophy, a common disorder in pediatric population can present as a variety of symptoms including snoring, nasal obstruction and hyponasal speech to obstructive sleep apnea (OSA), chronic rhinosinusitis and recurrent otitis media. Here we present a four years old boy presenting with periodic hematemesis for several months and the complaint of persistent presence of blood in saliva for whom complete GI evaluation revealed no obvious source. After otolaryngology consultation, detailed history and nasopharyngoscopy revealed hypertrophied adenoids as the source of bleeding. Surgical adenoidectomy was curative after 9 months follow up. This paper presented our experience in the management of an adenoid hypertrophy case presenting with oropharyngeal bleeding due to a mass-like lesion that is, to our knowledge, the first case of this issue.

Research paper thumbnail of Investigating the frequency of adenoid hypertrophy and allergic rhinitis in children with mouth breathing complaints

Background and Objectives: Nocturnal snoring and open mouth breathing in children is one of the c... more Background and Objectives: Nocturnal snoring and open mouth breathing in children is one of the common causes of referrals to pediatricians. The two most common reasons of this problem are adenotonsillar hypertrophy and allergic rhinitis. Based on the findings, there is still no significant relationship between these two diseases. Therefore, the aim of this study was to determine the frequency of adenoid hypertrophy and allergic rhinitis in children with mouth breathing complaints who referred to the allergy or ENT clinic of Ali Asghar Hospital in Tehran during 2015-2016. Methods: The population included all children between the ages of 4 and 12 years with symptoms of mouth breathing and nocturnal snoring referred to Allergy clinic of Ali Asghar Hospital during 2015-2016. These patients were examined by allergy sub-specialist in terms of atopy, allergic rhinitis, and allergy tests history. Patients were also examined by hospital otolaryngologist and otolaryngologist and the severity...

Research paper thumbnail of Language Sample Analysis in Children With Cleft Lip and Palate

Iranian Rehabilitation Journal, 2021

Objectives: Cleft Palate (CP) with or without Cleft Lip (CL/P) are the most common craniofacial b... more Objectives: Cleft Palate (CP) with or without Cleft Lip (CL/P) are the most common craniofacial birth defects. Cleft Lip and Palate (CLP) can affect children’s communication skills. The present study aimed to evaluate language production skills concerning morphology and syntax (morphosyntactic) in children with CLP. Methods: In the current cross-sectional study, 58 Persian-speaking children (28 children with CLP & 30 children without craniofacial anomalies=non-clefts) participated. Gathering the language samples of the children was conducted using the picture description method. The 50 consecutive intelligible utterances of children were analyzed by the Persian Developmental Sentence Scoring (PDSS), as a clinical morphosyntactic measurement tool. Results: The PDSS total scores of children with CLP were lower than those of the non-clefts children. A significant difference was found between the studied children with CLP and children without craniofacial anomalies in the mean value of ...

Research paper thumbnail of Is there any association between adenoid biofilm and upper airway infections in pediatric patients?

Türk Pediatri Arşivi, 2018

Üst solunum yolu obstrüksiyonu olan çocuklarda adenoid biyofilmlerin varlığı ve derecesi ile üst ... more Üst solunum yolu obstrüksiyonu olan çocuklarda adenoid biyofilmlerin varlığı ve derecesi ile üst solunum yolu enfeksiyonlarının sıklığı arasındaki ilişkiyi değerlendirmek. Gereç ve Yöntemler: Bu kesitsel çalışma, obstrüktif uyku apnesi nedeni ile adenoidektomi adayı olan çocuk hastalarda Ekim 2014 ile Aralık 2015 tarihleri arasında yürütülmüştür. Adenoid doku çıkarıldıktan ve %2,5 gluteraldehid içinde fikse edildikten sonra örnekler elektron mikroskobi birimine gönderilmiştir. Biyofilm oluşma derecesi, çevresel taramalı elektron mikroskopisi kullanılarak incelenmiştir. Bu sonuçlar daha sonra görüntü çözümleme programı kullanılarak doğrulanmıştır. Bulgular: Ortalama yaşı 7,31 (±2,65) olan 57 çocuk çalışmaya alınmıştır. Bu çocukların 43 tanesi (%75,4) erkekti ve 14 tanesi (%24,6) kızdı. Adenoidektomiden önce son 12 ay içinde üst solunum yolu enfeksiyonlarının ortalama sayısı 10,01 (±5,38) olarak saptanmıştır. Örneklerin hepsinde (%100) biyofilm yapıları saptanmıştır. Temel sonuç olarak, biyofilm derecesi, üst solunum yolu enfeksiyonlarının sıklığı ile anlamlı bir korelasyon göstermiştir (p<0,001). Cinsiyet ve adenoid boyutu ile biyofilm derecesi arasında anlamlı korelasyon saptanmamıştır. Çıkarımlar: Bu çalışma, adenoid biyofilm derecesinin üst solunum yolu enfeksiyonlarının sıklığı ile anlamlı bir ilişkisi olduğunu göstermiştir. Adenoid yüzeyi üzerinde mikroorganizmalar için bir rezervuar işlevi gören bir biyofilmin varlığı kronik enflamasyona neden olabilmektedir.

Research paper thumbnail of Tongue carcinoma: Case series and demographic analysis

Journal of Research in Clinical Medicine, Aug 25, 2013

BACKGROUND: Oral tongue squamous cell carcinoma (SCC) accounts for approximately half of oral cav... more BACKGROUND: Oral tongue squamous cell carcinoma (SCC) accounts for approximately half of oral cavity SCC cases. Smoking and drinking are two major risk factors for SCC worldwide. Recently, increasing incidence among young white individuals who were never-smoker, never-drinker have been reported. METHODS: To determine the demographic status of tongue SCC in our region, this study was conducted among patients who undergone surgery in Tabriz, Iran, due to tongue SCC. RESULTS: Mean age of 27 patients was 61 years and 22% of them were under 45 years old. Mean duration of beginning the symptoms to biopsy was 113 days for patients under the age of 60 years and 253 days for elderly patients (P = 0.026). Early diagnosis, especially in patients more than 60 years old, was associated with good prognosis. CONCLUSIONS: The results of this study indicated that considering a lower threshold for obtaining biopsy from elderly patients, even in the first visit, is useful for early diagnosis and better prognosis.

Research paper thumbnail of The prevalence of human papillomavirus in patients with oral lichen planus and normal oral mucosa

Research paper thumbnail of Dysphagia and dyspnea by lingual thyroid mass: An appropriate approach

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2015

Lingual thyroid is a rare embryological anomaly originated from the thyroid gland failure that de... more Lingual thyroid is a rare embryological anomaly originated from the thyroid gland failure that descends from the foramen cecum to its normal eutopic pre-laryngeal site. The case in this study was a 39 year old female, presenting with the sensation of a foreign body, progressive dysphagia and dyspnea. Indirect laryngoscopy revealed a large well-defined mass in the tongue base. Imaging studies confirmed the diagnosis of large ectopic lingual thyroid. The surgery was performed via an external cervical approach due to the mass size. The decision on the best treatment looks into the mass position, size, symptoms, airway emergency and medical facilities.

Research paper thumbnail of Growth hormone deficiency in cleft lip and palate patients

Journal of Analytical Research in Clinical Medicine, 2015

One of the most common congenital anomalies in the head and neck region is oropharyngeal cleft. T... more One of the most common congenital anomalies in the head and neck region is oropharyngeal cleft. The incidence of cleft lip and palate has been reported to be 1 in 700 live births, which might be isolated or associated with other syndromes. 1,2 It seems incidence of cleft lip and palate is a little lower in our country as some authors estimated it from 0.8 to 1.03 in 1000 live birth. 3,4 Approximately 250000 children with clefts are born all over the world annually, necessitating complicated and multiple surgeries and special care. Orofacial cleft is a multifactorial entity, with predisposing factors such as race, nutritional deficiencies, viral infections during pregnancy, heredity, environmental toxins, mother's contact with tobacco, use of alcohol, and some medications such as phenytoin and steroids. 2,5 Some problems associated with this condition include hearing problems, Cleft Lip,

Research paper thumbnail of Cleft palate lateral synechia syndrome: Inhereditary or not?

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2014

Cleft palate lateral synechia syndrome (CPLS) is a very rare syndrome characterized by a cleft pa... more Cleft palate lateral synechia syndrome (CPLS) is a very rare syndrome characterized by a cleft palate, adhesions in the mouth roof, some parts of the tongue or the mouth floor. This is a report of a 12-week-old female infant presented for evaluation of cleft palate, with lateral synechia that caused the inability to fully open the mouth. Release of the synechia was performed without complications. Although some researchers believe CPLS is inherited in an autosomal recessive pattern, our case indicated that a new mutation may cause this situation. Further research is recommended to clearly determine its inheredited and phenotypic variablities.

Research paper thumbnail of Effect of adenotonsillectomy on ADHD symptoms of children with adenotonsillar hypertrophy and sleep disordered breathing

International Journal of Pediatric Otorhinolaryngology, 2015

Background: Adenotonsillar hypertrophy is the most common etiologic agent for the obstruction of ... more Background: Adenotonsillar hypertrophy is the most common etiologic agent for the obstruction of the upper airways in children, which might be associated with attention-deficit hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood. Despite the concurrence of these two conditions, i.e., obstruction of the airways and ADHD, no exact etiologic relationship has been established between adenotonsillectomy (AT) and ADHD symptoms. This study was undertaken to evaluate the effect of AT on the ADHD symptoms in children with adenotonsillar hypertrophy and sleep disordered breathing (SDB). Methods: The design of the present study consisted of pre-test and post-test, followed by post hoc tests. Fifty-three children aged 3-12 were included in this study, selected from those referring to the Pediatric Hospital of Tabriz University of Medical Sciences, with SDB, adenotonsillar hypertrophy and ADHD based on DSM-IV criteria, by availability of the subjects undergoing adenotonsillectomy after evaluation of the severity of ADHD symptoms. The scores of ADHD symptoms were evaluated before AT and at 3-and 6month postoperative intervals based on Conner's Parent Rating Scale-Revised (CPRS-R) Questionnaire. Repeated-measures ANOVA and Fisher's exact test were used for data analysis. Results: AT resulted in a significant decrease in the severity of ADHD symptoms (oppositional behavior, cognitive disorders, inattention, hyperactivity and ADHD index) at 3-and 6-month postoperative intervals (P < 0.001), with more significant decreases at 6-month postoperative interval compared to 3month interval (P < 0.001). Conclusions: Based on the results of this pilot study, AT in children with SDB associated with ADHD resulted in a significant decrease in the severity of ADHD symptoms.

Research paper thumbnail of Relationship Between Serum Vitamin D Levels and Serous Otitis Media in Children with Adenoid Hypertrophy Based on Age

Thrita, Jun 1, 2020

Background: Serous Otitis Media (SOM) is one of the most common diseases of children that can lea... more Background: Serous Otitis Media (SOM) is one of the most common diseases of children that can lead to hearing loss and imbalance. Recently, the role of vitamin D has been identified in strengthening and regulating the immune system. Moreover, vitamin D supplementation has been recognized to improve the immune response against upper respiratory infection and pathogen overgrowth. Methods: A cross-sectional study was performed on 89 children aged 1-15 years with adenoid hypertrophy who met the inclusion criteria. The serum vitamin D level was compared between the two groups of children with and without SOM. Results: The mean age of the target children was 69.57 ± 25.65 months. The mean serum vitamin D level was 23.86 ± 12.7 in all patients. The mean serum vitamin D level was 24.7 ± 13.1 and 22.9 ± 12.2 in patients with and without SOM (based on tympanometry), respectively, yet the difference was not statistically significant. However, the difference was significant between the two groups of children with the age of < 84 months and > 84 months (P = 0.05). Conclusions: The role of vitamin D was identified in increasing the incidence of SOM in children older than 84 months with adenoid hypertrophy. In older children, the timely diagnosis and treatment of vitamin D deficiency can prevent severe SOM complications, which can save a lot of costs for families and the health system.

Research paper thumbnail of A Systematic Review on Machine Learning Techniques for Early Detection of Mental, Neurological and Laryngeal Disorders Using Patient’s Speech

Electronics

There is a substantial unmet need to diagnose speech-related disorders effectively. Machine learn... more There is a substantial unmet need to diagnose speech-related disorders effectively. Machine learning (ML), as an area of artificial intelligence (AI), enables researchers, physicians, and patients to solve these issues. The purpose of this study was to categorize and compare machine learning methods in the diagnosis of speech-based diseases. In this systematic review, a comprehensive search for publications was conducted on the Scopus, Web of Science, PubMed, IEEE and Cochrane databases from 2002–2022. From 533 search results, 48 articles were selected based on the eligibility criteria. Our findings suggest that the diagnosing of speech-based diseases using speech signals depends on culture, language and content of speech, gender, age, accent and many other factors. The use of machine-learning models on speech sounds is a promising pathway towards improving speech-based disease diagnosis and treatments in line with preventive and personalized medicine.

Research paper thumbnail of Allergy status in children with adenoid hypertrophy with and without serous otitis media

Immunopathologia Persa

Introduction: Serous otitis media (SOM) is one of the most common diseases of children which can ... more Introduction: Serous otitis media (SOM) is one of the most common diseases of children which can lead to hearing loss and imbalance in many cases. Objective: To evaluate the relationship between allergy status and SOM in children with adenoid hypertrophy and whether affected by age group. Materials and Methods: This cross-sectional study was conducted on 103 children aged 1-15 years with grade III or IV adenoid hypertrophy (± SOM) who referred to ear, nose, and throat (ENT) clinic. Additionally, children were divided into two subgroups based on age category of below and above seven years. The allergy status in children with and without SOM was compared by measuring the total immunoglobulin E (IgE) level, serum eosinophil level and skin prick test (SPT). Results: There was no difference in prevalence of mean absolute eosinophil count (127.3 versus 141.3 eosinophils/ µL, respectively) (P=0.63), mean total IgE level (68.2 versus 140 IU/L, respectively; P=0.119) and positive SPT results...

Research paper thumbnail of Development of a mobile application for self-care of patients with cleft lip and palate

Razi Journal of Medical Sciences, Aug 10, 2021

Research paper thumbnail of Evaluation of adenoid tissue culture according to biofilm grade and annual rate of upper respiratory tract infection in children with upper airway obstruction

Razi Journal of Medical Sciences, Jun 10, 2020

Research paper thumbnail of Designing and Developing a Self-Care Application for Post-Laryngectomy Surgery

Journal of Health and Biomedical Informatics, Jun 10, 2021

Research paper thumbnail of Serum Level of Interleukin-6 in Patients with Oral Tongue

2 The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and nec... more 2 The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to

Research paper thumbnail of Root Cause Analysis of Falling out of bed in one of the Pediatric Hospitals in Tehran in 2019-2020

Health Monitor Journal of the Iranian Institute for Health Sciences Research, 2021

Objective (s): Children are one of the most vulnerable groups in falls from hospital beds, becaus... more Objective (s): Children are one of the most vulnerable groups in falls from hospital beds, because usually this might cause head injurie. There are limited researches to prevent children from falling. Therefore, this study was performed to analyze the roots cause factors affecting the fall in children. Methods: This was a cross-sectional study. First the adverse events were measured using a monthly error recording form, then the root cause analysis of the problem was performed in six steps, problem identification, team formation, preparation of initial information and final map, identification of causes and drawing tables, identification of solutions and implementation and assessment of solutions. Results: Lack of effective training of patient companions, old hospital beds, short, and long distance between bed railings, training of nurses, and controlling of the restless children were obtained as a root causes based on futuristic barrier analysis. The solutions were identified and implemented and the comparison of statistics before and after the implementation of the strategies showed that the rate of falling from the bed in the third quarter of the year has reached to zero percent. Conclusion: Educating the patient companions about the keeping of the bed railings high and not leaving the child can have a great impact on reducing falls. Also, standardizing hospital beds, providing fall prevention guidelines for nurses, training the effective communication skills, and identifying high-risk children can help to reduce falls and injuries.

Research paper thumbnail of A Bilateral Tessier Number 4 and 5 Facial Cleft and Surgical Strategy: A Case Report

Iranian Journal of Otorhinolaryngology, 2013

Introduction: Tessier facial cleft is among the rarest facial clefts reported in literatures and ... more Introduction: Tessier facial cleft is among the rarest facial clefts reported in literatures and there are many issues arguing about its multidisciplinary repairing techniques. Tessier number 4 and 5 are extremely rare facial anomalies. There are few literatures describing these clefts and their surgical modalities. Number 5 Tessier cleft begins medial to oral commissure in the upper lip and extends superiorly as a groove through the cheek and ends at the middle third of lower eyelid. Bonny involvement consists of alveolar ridge, maxillary bone lateral to infra orbital foramen and orbits lower rim and floor. Number 4 Tessier facial cleft begins between cupid bow and oral commissure; skirting the nose and pass through cheek and lateral to lacrimal duct. Bonny involvement consists of alveolar ridge, maxillary bone medial to infra orbital foramen and orbital rim and floor. Case Report: This paper represents a patient with bilateral number 4 and 5 Tessier cleft lip with unilateral compl...

Research paper thumbnail of Serum Level of Interleukin-6 in Patients with Oral Tongue Squamous cell Carcinoma

Iranian Journal of Otorhinolaryngology, 2015

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the ... more Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum levels of interleukin-6 in patients with oral tongue SCC. Materials and Methods: In a cross-sectional study, 17 patients with oral tongue SCC were compared with the same number of age- and gender-matched healthy subjects. Serum IL-6 level fluctuation was determined using an immunological technique, before detecting its possible association with the subjects’ age, gender, drinking and smoking history, cancer site, and disease severity. Results: The intensity of serum IL-6 in patients with oral tongue SCC was statistically significantly higher than that in healthy subjects (P<0.001). Serum IL-6...

Research paper thumbnail of Spontaneous Adenoid Hemorrhage Mimicking Upper GastrointestinalBleeding

Otolaryngology online journal, 2017

Adenoid hypertrophy, a common disorder in pediatric population can present as a variety of sympto... more Adenoid hypertrophy, a common disorder in pediatric population can present as a variety of symptoms including snoring, nasal obstruction and hyponasal speech to obstructive sleep apnea (OSA), chronic rhinosinusitis and recurrent otitis media. Here we present a four years old boy presenting with periodic hematemesis for several months and the complaint of persistent presence of blood in saliva for whom complete GI evaluation revealed no obvious source. After otolaryngology consultation, detailed history and nasopharyngoscopy revealed hypertrophied adenoids as the source of bleeding. Surgical adenoidectomy was curative after 9 months follow up. This paper presented our experience in the management of an adenoid hypertrophy case presenting with oropharyngeal bleeding due to a mass-like lesion that is, to our knowledge, the first case of this issue.

Research paper thumbnail of Investigating the frequency of adenoid hypertrophy and allergic rhinitis in children with mouth breathing complaints

Background and Objectives: Nocturnal snoring and open mouth breathing in children is one of the c... more Background and Objectives: Nocturnal snoring and open mouth breathing in children is one of the common causes of referrals to pediatricians. The two most common reasons of this problem are adenotonsillar hypertrophy and allergic rhinitis. Based on the findings, there is still no significant relationship between these two diseases. Therefore, the aim of this study was to determine the frequency of adenoid hypertrophy and allergic rhinitis in children with mouth breathing complaints who referred to the allergy or ENT clinic of Ali Asghar Hospital in Tehran during 2015-2016. Methods: The population included all children between the ages of 4 and 12 years with symptoms of mouth breathing and nocturnal snoring referred to Allergy clinic of Ali Asghar Hospital during 2015-2016. These patients were examined by allergy sub-specialist in terms of atopy, allergic rhinitis, and allergy tests history. Patients were also examined by hospital otolaryngologist and otolaryngologist and the severity...

Research paper thumbnail of Language Sample Analysis in Children With Cleft Lip and Palate

Iranian Rehabilitation Journal, 2021

Objectives: Cleft Palate (CP) with or without Cleft Lip (CL/P) are the most common craniofacial b... more Objectives: Cleft Palate (CP) with or without Cleft Lip (CL/P) are the most common craniofacial birth defects. Cleft Lip and Palate (CLP) can affect children’s communication skills. The present study aimed to evaluate language production skills concerning morphology and syntax (morphosyntactic) in children with CLP. Methods: In the current cross-sectional study, 58 Persian-speaking children (28 children with CLP & 30 children without craniofacial anomalies=non-clefts) participated. Gathering the language samples of the children was conducted using the picture description method. The 50 consecutive intelligible utterances of children were analyzed by the Persian Developmental Sentence Scoring (PDSS), as a clinical morphosyntactic measurement tool. Results: The PDSS total scores of children with CLP were lower than those of the non-clefts children. A significant difference was found between the studied children with CLP and children without craniofacial anomalies in the mean value of ...

Research paper thumbnail of Is there any association between adenoid biofilm and upper airway infections in pediatric patients?

Türk Pediatri Arşivi, 2018

Üst solunum yolu obstrüksiyonu olan çocuklarda adenoid biyofilmlerin varlığı ve derecesi ile üst ... more Üst solunum yolu obstrüksiyonu olan çocuklarda adenoid biyofilmlerin varlığı ve derecesi ile üst solunum yolu enfeksiyonlarının sıklığı arasındaki ilişkiyi değerlendirmek. Gereç ve Yöntemler: Bu kesitsel çalışma, obstrüktif uyku apnesi nedeni ile adenoidektomi adayı olan çocuk hastalarda Ekim 2014 ile Aralık 2015 tarihleri arasında yürütülmüştür. Adenoid doku çıkarıldıktan ve %2,5 gluteraldehid içinde fikse edildikten sonra örnekler elektron mikroskobi birimine gönderilmiştir. Biyofilm oluşma derecesi, çevresel taramalı elektron mikroskopisi kullanılarak incelenmiştir. Bu sonuçlar daha sonra görüntü çözümleme programı kullanılarak doğrulanmıştır. Bulgular: Ortalama yaşı 7,31 (±2,65) olan 57 çocuk çalışmaya alınmıştır. Bu çocukların 43 tanesi (%75,4) erkekti ve 14 tanesi (%24,6) kızdı. Adenoidektomiden önce son 12 ay içinde üst solunum yolu enfeksiyonlarının ortalama sayısı 10,01 (±5,38) olarak saptanmıştır. Örneklerin hepsinde (%100) biyofilm yapıları saptanmıştır. Temel sonuç olarak, biyofilm derecesi, üst solunum yolu enfeksiyonlarının sıklığı ile anlamlı bir korelasyon göstermiştir (p<0,001). Cinsiyet ve adenoid boyutu ile biyofilm derecesi arasında anlamlı korelasyon saptanmamıştır. Çıkarımlar: Bu çalışma, adenoid biyofilm derecesinin üst solunum yolu enfeksiyonlarının sıklığı ile anlamlı bir ilişkisi olduğunu göstermiştir. Adenoid yüzeyi üzerinde mikroorganizmalar için bir rezervuar işlevi gören bir biyofilmin varlığı kronik enflamasyona neden olabilmektedir.

Research paper thumbnail of Tongue carcinoma: Case series and demographic analysis

Journal of Research in Clinical Medicine, Aug 25, 2013

BACKGROUND: Oral tongue squamous cell carcinoma (SCC) accounts for approximately half of oral cav... more BACKGROUND: Oral tongue squamous cell carcinoma (SCC) accounts for approximately half of oral cavity SCC cases. Smoking and drinking are two major risk factors for SCC worldwide. Recently, increasing incidence among young white individuals who were never-smoker, never-drinker have been reported. METHODS: To determine the demographic status of tongue SCC in our region, this study was conducted among patients who undergone surgery in Tabriz, Iran, due to tongue SCC. RESULTS: Mean age of 27 patients was 61 years and 22% of them were under 45 years old. Mean duration of beginning the symptoms to biopsy was 113 days for patients under the age of 60 years and 253 days for elderly patients (P = 0.026). Early diagnosis, especially in patients more than 60 years old, was associated with good prognosis. CONCLUSIONS: The results of this study indicated that considering a lower threshold for obtaining biopsy from elderly patients, even in the first visit, is useful for early diagnosis and better prognosis.

Research paper thumbnail of The prevalence of human papillomavirus in patients with oral lichen planus and normal oral mucosa

Research paper thumbnail of Dysphagia and dyspnea by lingual thyroid mass: An appropriate approach

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2015

Lingual thyroid is a rare embryological anomaly originated from the thyroid gland failure that de... more Lingual thyroid is a rare embryological anomaly originated from the thyroid gland failure that descends from the foramen cecum to its normal eutopic pre-laryngeal site. The case in this study was a 39 year old female, presenting with the sensation of a foreign body, progressive dysphagia and dyspnea. Indirect laryngoscopy revealed a large well-defined mass in the tongue base. Imaging studies confirmed the diagnosis of large ectopic lingual thyroid. The surgery was performed via an external cervical approach due to the mass size. The decision on the best treatment looks into the mass position, size, symptoms, airway emergency and medical facilities.

Research paper thumbnail of Growth hormone deficiency in cleft lip and palate patients

Journal of Analytical Research in Clinical Medicine, 2015

One of the most common congenital anomalies in the head and neck region is oropharyngeal cleft. T... more One of the most common congenital anomalies in the head and neck region is oropharyngeal cleft. The incidence of cleft lip and palate has been reported to be 1 in 700 live births, which might be isolated or associated with other syndromes. 1,2 It seems incidence of cleft lip and palate is a little lower in our country as some authors estimated it from 0.8 to 1.03 in 1000 live birth. 3,4 Approximately 250000 children with clefts are born all over the world annually, necessitating complicated and multiple surgeries and special care. Orofacial cleft is a multifactorial entity, with predisposing factors such as race, nutritional deficiencies, viral infections during pregnancy, heredity, environmental toxins, mother's contact with tobacco, use of alcohol, and some medications such as phenytoin and steroids. 2,5 Some problems associated with this condition include hearing problems, Cleft Lip,

Research paper thumbnail of Cleft palate lateral synechia syndrome: Inhereditary or not?

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2014

Cleft palate lateral synechia syndrome (CPLS) is a very rare syndrome characterized by a cleft pa... more Cleft palate lateral synechia syndrome (CPLS) is a very rare syndrome characterized by a cleft palate, adhesions in the mouth roof, some parts of the tongue or the mouth floor. This is a report of a 12-week-old female infant presented for evaluation of cleft palate, with lateral synechia that caused the inability to fully open the mouth. Release of the synechia was performed without complications. Although some researchers believe CPLS is inherited in an autosomal recessive pattern, our case indicated that a new mutation may cause this situation. Further research is recommended to clearly determine its inheredited and phenotypic variablities.

Research paper thumbnail of Effect of adenotonsillectomy on ADHD symptoms of children with adenotonsillar hypertrophy and sleep disordered breathing

International Journal of Pediatric Otorhinolaryngology, 2015

Background: Adenotonsillar hypertrophy is the most common etiologic agent for the obstruction of ... more Background: Adenotonsillar hypertrophy is the most common etiologic agent for the obstruction of the upper airways in children, which might be associated with attention-deficit hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood. Despite the concurrence of these two conditions, i.e., obstruction of the airways and ADHD, no exact etiologic relationship has been established between adenotonsillectomy (AT) and ADHD symptoms. This study was undertaken to evaluate the effect of AT on the ADHD symptoms in children with adenotonsillar hypertrophy and sleep disordered breathing (SDB). Methods: The design of the present study consisted of pre-test and post-test, followed by post hoc tests. Fifty-three children aged 3-12 were included in this study, selected from those referring to the Pediatric Hospital of Tabriz University of Medical Sciences, with SDB, adenotonsillar hypertrophy and ADHD based on DSM-IV criteria, by availability of the subjects undergoing adenotonsillectomy after evaluation of the severity of ADHD symptoms. The scores of ADHD symptoms were evaluated before AT and at 3-and 6month postoperative intervals based on Conner's Parent Rating Scale-Revised (CPRS-R) Questionnaire. Repeated-measures ANOVA and Fisher's exact test were used for data analysis. Results: AT resulted in a significant decrease in the severity of ADHD symptoms (oppositional behavior, cognitive disorders, inattention, hyperactivity and ADHD index) at 3-and 6-month postoperative intervals (P < 0.001), with more significant decreases at 6-month postoperative interval compared to 3month interval (P < 0.001). Conclusions: Based on the results of this pilot study, AT in children with SDB associated with ADHD resulted in a significant decrease in the severity of ADHD symptoms.