Giovanni Baldi - Academia.edu (original) (raw)

Papers by Giovanni Baldi

Journal of The European Ceramic Society, 2009

Abstract Metallic (Ag, Au, Cu) nanoparticles suspensions are gaining an increasing interest in me... more Abstract Metallic (Ag, Au, Cu) nanoparticles suspensions are gaining an increasing interest in medical applications. Among the existing synthetic routes available, microwave processing allows to better control particle size and to achieve high purity of the products. The large scale production of nanoparticles requires the development of industrially-viable processes, preferably conducted using a “green chemistry” approach, at ambient pressure and relatively low temperature. Based on a recently developed microwave-assisted ...

IEEE journal of electromagnetics, RF and microwaves in medicine and biology, Mar 1, 2018

Analytical characterization of magnetic nanoparticles based on SAR experimental measurements. Tak... more Analytical characterization of magnetic nanoparticles based on SAR experimental measurements. Take-Home Messages • A novel approach able to deeply optimize clinical treatments of magnetic hyperthermia with nanoparticles. • Innovative determination of the complex magnetic permeability of magnetic colloidal fluid by simply using in vitro SAR measurements. • A rapid, alternative and broadband approach for determining the electromagnetic properties of magnetic nanoparticles. • Possibility to test the efficiency of nanoparticles in a tissue-like environment: optimized and realistic treatment planning for magnetic hyperthermia.

Journal of The European Ceramic Society, May 1, 2002

... Riccardo Ricceri a , Silvia Ardizzone b , Giovanni Baldi c and Paolo Matteazzi Corresponding ... more ... Riccardo Ricceri a , Silvia Ardizzone b , Giovanni Baldi c and Paolo Matteazzi Corresponding Author Contact Information , E-mail The Corresponding Author , a. ... Specific surface areas were determined by the classical BET procedure using a Coulter SA 3100 apparatus. 2.2. ...

Materials Science and Engineering: C, Aug 1, 2017

Bioactivity, mechanical properties and drug delivery ability of bioactive glass-ceramic scaffolds... more Bioactivity, mechanical properties and drug delivery ability of bioactive glass-ceramic scaffolds coated with a natural-derived polymer. The address for the corresponding author was captured as affiliation for all authors. Please check if appropriate. Msc(2017),

Particle and Fibre Toxicology, 2009

Background: During the last years engineered nanoparticles (NPs) have been extensively used in di... more Background: During the last years engineered nanoparticles (NPs) have been extensively used in different technologies and consequently many questions have arisen about the risk and the impact on human health following exposure to nanoparticles. Nevertheless, at present knowledge about the cytotoxicity induced by NPs is still largely incomplete. In this context, we have investigated the cytotoxicity induced by gold nanoparticles (AuNPs), which differed in size and purification grade (presence or absence of sodium citrate residues on the particle surface) in vitro, in the human alveolar type-II (ATII)-like cell lines A549 and NCIH441. Results: We found that the presence of sodium citrate residues on AuNPs impaired the viability of the ATII-like cell lines A549 and NCIH441. Interestingly, the presence of an excess of sodium citrate on the surface of NPs not only reduced the in vitro viability of the cell lines A549 and NCIH441, as shown by MTT assay, but also affected cellular proliferation and increased the release of lactate dehydrogenase (LDH), as demonstrated by Ki-67 and LDH-release assays respectively. Furthermore, we investigated the internalization of AuNPs by transmission electron microscopy (TEM) and we observed that particles were internalized by active endocytosis in the cell lines A549 and NCIH441 within 3 hr. In addition, gold particles accumulated in membrane-bound vesicles and were not found freely dispersed in the cytoplasm. Conclusion: Our data suggest that the presence of contaminants, such as sodium citrate, on the surface of gold nanoparticles might play a pivotal role in inducing cytotoxicity in vitro, but does not influence the uptake of the particles in human ATII-like cell lines.

Dyes and Pigments, Feb 1, 2009

Ceramic nano-pigments have been recently developed for ink-jet printing decoration of ceramic til... more Ceramic nano-pigments have been recently developed for ink-jet printing decoration of ceramic tiles by the quadrichromy technology (cyan, magenta, yellow, and black colours). The colouring mechanisms and performance of these nano-pigments (CoAl 2 O 4 , Au, (Ti,Cr,Sb)O 2 , CoFe 2 O 4) were investigated by DRS, XRD and colourimetry. Nano-pigments were dispersed in several ceramic glazes and glassy coatings and their colour performance compared with that of conventional micro-pigments. Each nano-pigment is characterized by its own colour mechanism and chemico-physical stability in ceramic applications. Intense colours are achievable, besides the very small particle size of pigments (< 50 nm) even though the colour of high quality micropigments appears to be more saturated. Limitations to the use of nano-pigments arose for very high firing temperatures (>1200ºC) due to particle growth (e.g. Au) or dissolution in the glassy phase (e.g. titania).

Molecules, Feb 16, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Ceramics International, Apr 1, 2008

In the present work, the effects of glass ceramic frits (10wt%) added to a porcelain stoneware bo... more In the present work, the effects of glass ceramic frits (10wt%) added to a porcelain stoneware body in replacement of non-plastic raw materials, were evaluated simulating the tile-making process. Each glass ceramic frit plays its own peculiar effect on the compositional properties and only some precursors behave as real glass ceramic materials. The positive influence of glass ceramic precursors in promoting the sintering stands out when temperature onset densification and sintering rate are considered: both of them are improved with respect to the reference body. The presence of glass ceramic frits allows the preserve good technological properties, complying with the latest requirements of the industrials practice.

Advances in Applied Ceramics, Oct 1, 2008

This paper is a critical discussing key on previous results of the authors in the field of glassc... more This paper is a critical discussing key on previous results of the authors in the field of glassceramic scaffolds for tissue engineering. With the aim of developing biological substitutes that restore, maintain or improve tissue functionality, glass-ceramic scaffolds were produced starting from a glass system composition enriched with traces of specific elements. The presence of one or more specific ions can modulate the better environmental conditions to favour the growth of specific specialised cells, a necessary prerequisite to originate different kinds of tissues. The main predictable use is for bone reconstruction, but other possible uses are expectable for some specific tissues (cartilage, nerve, tendons, etc.). In order to obtain the best initial tissue integration, a decisive role is played by porosity of the glass scaffold. The glass structure can generally be resorbed, leaving its volume available for tissue nodules which grow and assemble together, producing an equal volume of tissue. In bone, the action is synergically increased thanks to the phenomena of bone conduction and bone induction of the proposed porous bioactive ceramics. On the other hand, glass-ceramic scaffolds have already been appreciated as a superior material for bone healing. Compared to similar hydroxyapatite structures, the glassceramic ones exhibit a greater starting mechanical resistance (useful for surgical manipulations) and differently from the hydroxyapatite ones, they are resorbed more easily in time. This is a good requisite for a material to be used in bone tissue engineering. The ceramic bioactive systems can be used both in bulk and as coatings.

Nanomaterials

Ferroptosis, a form of iron-dependent, lipid peroxidation-driven cell death, has been extensively... more Ferroptosis, a form of iron-dependent, lipid peroxidation-driven cell death, has been extensively investigated in recent years, and several studies have suggested that the ferroptosis-inducing properties of iron-containing nanomaterials could be harnessed for cancer treatment. Here we evaluated the potential cytotoxicity of iron oxide nanoparticles, with and without cobalt functionalization (Fe2O3 and Fe2O3@Co-PEG), using an established, ferroptosis-sensitive fibrosarcoma cell line (HT1080) and a normal fibroblast cell line (BJ). In addition, we evaluated poly (ethylene glycol) (PEG)-poly(lactic-co-glycolic acid) (PLGA)-coated iron oxide nanoparticles (Fe3O4-PEG-PLGA). Our results showed that all the nanoparticles tested were essentially non-cytotoxic at concentrations up to 100 μg/mL. However, when the cells were exposed to higher concentrations (200–400 μg/mL), cell death with features of ferroptosis was observed, and this was more pronounced for the Co-functionalized nanoparticle...

ACS Applied Nano Materials

Journal of Environmental Chemical Engineering

INCA Consorzio Interuniversitario Nazionale "La Chimica per l'Ambiente" VIII Congresso – Chimica sostenibile & Tecnologie ambientali: stato dell’arte e prospettive,, 2006

Journal of the European Ceramic Society, 2016

Highly bioactive glass coatings were successfully achieved by applying a newly developed bioactiv... more Highly bioactive glass coatings were successfully achieved by applying a newly developed bioactive glass layer having a low Ca/P ratio on a ZrO 2-3%Y 2 O 3 ceramic substrate. The thermal properties of the glass allowed covering zirconia substrates both by amorphous and glass-ceramic coatings. The coatings exhibited 345 m thickness and were free from surface cracks, highlighting the good compatibility between the glass and the substrate in terms of expansion coefficient matching. The synthesized materials achieved the formation of a crystalline carbonate apatite layer after 3 days soaking in SBF solution. Although the slight diffusion of the amorphous and glass-ceramic coatings through the ZrO 2-3%Y 2 O 3 support (≤20 m and ≤100 m, respectively), the rate of formation of carbonate apatite layer was maintained in comparison with the native glass alone, constituting a promising material for application as dental prosthetic devices.

Biomedical glasses, 2015

In this work, sintered pellets of a silica-based bioactive glass were dip-coated with a biocompat... more In this work, sintered pellets of a silica-based bioactive glass were dip-coated with a biocompatible natural-derived polymer in order to investigate the influence of the organic coating on the glass bioactivity. After the sintering process optimization, uncoated and coated pellets have been characterized by means of scanning electron microscopy with energy dispersive spectroscopy (SEM, EDS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and pH measurements, after the immersion in a simulated body fluid (SBF). An increased apatite forming ability and a better control of the pH during soaking of the samples in SBF were observed in the presence of the biopolymer. This result opens a new insight on the simple fabrication of highly bioactive hybrid inorganic-organic materials for medical applications.

$Research paper thumbnail of Temperature-resolved synchrotron X-ray diffraction of nanocrystalline titania in solvent: the effect of Cr–Sb and V–Sb doping$

Journal of Nanoparticle Research, 2010

Nanocrystalline titania pigments were produced by high temperature-forced hydrolysis in a coordin... more Nanocrystalline titania pigments were produced by high temperature-forced hydrolysis in a coordinating high-boiling solvent (and water for reference). The effect of synthesis conditions and codoping with Cr-Sb and V-Sb on particle size and anatase-to-rutile transformation (A ? R) was studied by temperature-resolved synchrotron X-ray diffraction. The experiments were performed directly on low concentration (3.5 vol.%) as-synthesized suspensions of titania nanoparticles (up to 230°C) and on the corresponding dried powders (up to 950°C). Crystallite size of as-synthesized nano-anatase is around 20 nm (glycol) or 70 nm (water); it exhibits a slow growth rate up to the onset temperature of the A ? R. Phase composition and crystallite size are drastically influenced by both synthesis conditions and doping. Synthesis in water resulted in the simultaneous occurrence of anatase and brookite; transformation into rutile begins early but with a slower rate with respect to glycol-based samples. Doping affected the A ? R, whose onset temperature in undoped titania (700°C) was lowered to 650°C (V-Sb) or prevented up to 950°C (Cr-Sb). Both (V-Sb) and (Cr-Sb) dopings reduced the volume thermal expansion rate of anatase.