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Papers by Giovanni Della Mura
International Journal of Biological Macromolecules, 2005
Three-dimensional models for ␣B-crystallin and its complex with zinc were obtained by molecular h... more Three-dimensional models for ␣B-crystallin and its complex with zinc were obtained by molecular homology modeling and quantum mechanical calculations in order to explain the effect of the metal on the chaperone-like activity of ␣B-crystallin. In fact, measurements of the chaperone-like activity of ␣B-crystallin revealed that it is significantly increased in presence of the zinc. The theoretical models allowed us to estimate the increased exposition of hydrophobic residues caused by the presence of zinc, suggesting a relationship between structural changes and the increased chaperone-like activity.
Catalysis Today, 2005
Electrochemical measurements show that the enzyme Glucose oxidase (GO) is adsorbed on the surface... more Electrochemical measurements show that the enzyme Glucose oxidase (GO) is adsorbed on the surface of TiO 2 without apparently changing the flat band potential of the semiconductor, indicating that it does not cause a change of the energy of conduction band electrons. On the other hand, it is observed that GO markedly increases the efficiency of the two electron reduction of O 2 to H 2 O 2 which is accumulated in the solution phase. ESR spin trapping investigations indicate that GO favors the formation of OH. radicals, due to either the inhibition of charge recombination processes or to H 2 O 2 reduction by conduction band electrons. Accordingly, photo-oxidation of different alcohols to the corresponding radical species is also enhanced in the presence of GO. The photo-oxidation of 1,2-propandiol on TiO 2 /GO is regioselective in that i) partial oxidation to hydroxyacetone is observed and ii) no mineralization (full combustion to CO 2) of the substrate occurs. These facts are of particular interest in the 1
International Journal of Biological Macromolecules, 2005
Three-dimensional models for ␣B-crystallin and its complex with zinc were obtained by molecular h... more Three-dimensional models for ␣B-crystallin and its complex with zinc were obtained by molecular homology modeling and quantum mechanical calculations in order to explain the effect of the metal on the chaperone-like activity of ␣B-crystallin. In fact, measurements of the chaperone-like activity of ␣B-crystallin revealed that it is significantly increased in presence of the zinc. The theoretical models allowed us to estimate the increased exposition of hydrophobic residues caused by the presence of zinc, suggesting a relationship between structural changes and the increased chaperone-like activity.
Catalysis Today, 2005
Electrochemical measurements show that the enzyme Glucose oxidase (GO) is adsorbed on the surface... more Electrochemical measurements show that the enzyme Glucose oxidase (GO) is adsorbed on the surface of TiO 2 without apparently changing the flat band potential of the semiconductor, indicating that it does not cause a change of the energy of conduction band electrons. On the other hand, it is observed that GO markedly increases the efficiency of the two electron reduction of O 2 to H 2 O 2 which is accumulated in the solution phase. ESR spin trapping investigations indicate that GO favors the formation of OH. radicals, due to either the inhibition of charge recombination processes or to H 2 O 2 reduction by conduction band electrons. Accordingly, photo-oxidation of different alcohols to the corresponding radical species is also enhanced in the presence of GO. The photo-oxidation of 1,2-propandiol on TiO 2 /GO is regioselective in that i) partial oxidation to hydroxyacetone is observed and ii) no mineralization (full combustion to CO 2) of the substrate occurs. These facts are of particular interest in the 1