Glen Bremner - Academia.edu (original) (raw)

Papers by Glen Bremner

The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are rep... more The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are reported. Homo-and co-polymer films of these NPs were prepared electrochemically and studied using cyclic voltammetry, electron microscopy, and absorption xiii

Organic chemistry frontiers, 2019

Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated... more Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated sunlight.

Acs Symposium Series, Jun 22, 2006

A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. Th... more A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. The process is similar to fishing, where the target protein is like a specific type of fish. An antigen, covalently linked on a magnetic nanocrystal, is "the bait and hook"; the fishing line is simulated by an applied magnetic field. By selective binding the target protein can be caught, isolated and released from the nanocrystal support once the interaction of antigen-antibody is neutralized. Microcrystalline cellulose (MCC) is responsive to functionalization, as required to tether the desirable bioactive ligand. Chitin nanocrystals with some free surface amino groups are also as suitable as nanocrystal support. To render MCC magnetic, ferrous iron is adsorbed and converted to ferrous hydroxide, which is then oxidized with KNO 3 to form superparamagnetic magnetite. From the magnetization curves, the particle size distribution and magnetite content of ferrites in the polysaccharide matrix can be derived. A trial fishing experiment to isolate a target protein used a magnetized MCC platform to which Protein A, a specific ligand of Immunoglobulin G, IgG, was attached. The resulting magnetic platform, captured the target IgG which was magnetically separated from the supernatant. IgG was isolated by screening the non-bonded interactions between IgG and its specific ligand.

The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are rep... more The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are reported. Homo-and co-polymer films of these NPs were prepared electrochemically and studied using cyclic voltammetry, electron microscopy, and absorption xiii

ECS Meeting Abstracts, 2010

not Available.

Organic Chemistry Frontiers, 2019

Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated... more Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated sunlight.

Journal of the American Chemical Society, 2006

ACS Symposium Series, 2006

A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. Th... more A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. The process is similar to fishing, where the target protein is like a specific type of fish. An antigen, covalently linked on a magnetic nanocrystal, is "the bait and hook"; the fishing line is simulated by an applied magnetic field. By selective binding the target protein can be caught, isolated and released from the nanocrystal support once the interaction of antigen-antibody is neutralized. Microcrystalline cellulose (MCC) is responsive to functionalization, as required to tether the desirable bioactive ligand. Chitin nanocrystals with some free surface amino groups are also as suitable as nanocrystal support. To render MCC magnetic, ferrous iron is adsorbed and converted to ferrous hydroxide, which is then oxidized with KNO 3 to form superparamagnetic magnetite. From the magnetization curves, the particle size distribution and magnetite content of ferrites in the polysaccharide matrix can be derived. A trial fishing experiment to isolate a target protein used a magnetized MCC platform to which Protein A, a specific ligand of Immunoglobulin G, IgG, was attached. The resulting magnetic platform, captured the target IgG which was magnetically separated from the supernatant. IgG was isolated by screening the non-bonded interactions between IgG and its specific ligand.

The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are rep... more The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are reported. Homo-and co-polymer films of these NPs were prepared electrochemically and studied using cyclic voltammetry, electron microscopy, and absorption xiii

Organic chemistry frontiers, 2019

Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated... more Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated sunlight.

Acs Symposium Series, Jun 22, 2006

A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. Th... more A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. The process is similar to fishing, where the target protein is like a specific type of fish. An antigen, covalently linked on a magnetic nanocrystal, is "the bait and hook"; the fishing line is simulated by an applied magnetic field. By selective binding the target protein can be caught, isolated and released from the nanocrystal support once the interaction of antigen-antibody is neutralized. Microcrystalline cellulose (MCC) is responsive to functionalization, as required to tether the desirable bioactive ligand. Chitin nanocrystals with some free surface amino groups are also as suitable as nanocrystal support. To render MCC magnetic, ferrous iron is adsorbed and converted to ferrous hydroxide, which is then oxidized with KNO 3 to form superparamagnetic magnetite. From the magnetization curves, the particle size distribution and magnetite content of ferrites in the polysaccharide matrix can be derived. A trial fishing experiment to isolate a target protein used a magnetized MCC platform to which Protein A, a specific ligand of Immunoglobulin G, IgG, was attached. The resulting magnetic platform, captured the target IgG which was magnetically separated from the supernatant. IgG was isolated by screening the non-bonded interactions between IgG and its specific ligand.

The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are rep... more The synthesis and characterization of oligothiophene-capped Au and Cu nanoparticles (NPs) are reported. Homo-and co-polymer films of these NPs were prepared electrochemically and studied using cyclic voltammetry, electron microscopy, and absorption xiii

ECS Meeting Abstracts, 2010

not Available.

Organic Chemistry Frontiers, 2019

Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated... more Two unusual products are observed when benzofuran-based diartylethenes are weathered in simulated sunlight.

Journal of the American Chemical Society, 2006

ACS Symposium Series, 2006

A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. Th... more A key to proteomics exploitation is magnetic separation of target proteins in a sea of others. The process is similar to fishing, where the target protein is like a specific type of fish. An antigen, covalently linked on a magnetic nanocrystal, is "the bait and hook"; the fishing line is simulated by an applied magnetic field. By selective binding the target protein can be caught, isolated and released from the nanocrystal support once the interaction of antigen-antibody is neutralized. Microcrystalline cellulose (MCC) is responsive to functionalization, as required to tether the desirable bioactive ligand. Chitin nanocrystals with some free surface amino groups are also as suitable as nanocrystal support. To render MCC magnetic, ferrous iron is adsorbed and converted to ferrous hydroxide, which is then oxidized with KNO 3 to form superparamagnetic magnetite. From the magnetization curves, the particle size distribution and magnetite content of ferrites in the polysaccharide matrix can be derived. A trial fishing experiment to isolate a target protein used a magnetized MCC platform to which Protein A, a specific ligand of Immunoglobulin G, IgG, was attached. The resulting magnetic platform, captured the target IgG which was magnetically separated from the supernatant. IgG was isolated by screening the non-bonded interactions between IgG and its specific ligand.