Gonesh Karmakar - Academia.edu (original) (raw)

Papers by Gonesh Karmakar

Journal of Pharmacy Practice and Research, 2013

Background: Adherence to guidelines for community-acquired pneumonia (CAP) has been shown to impr... more Background: Adherence to guidelines for community-acquired pneumonia (CAP) has been shown to improve patient outcomes and slow the emergence of antimicrobial resistance. Guidelines for treating CAP vary considerably. Aim: To determine the initial antimicrobial therapy used in hospitalised adults with CAP and to compare it with local and international CAP treatment guidelines. Method: A retrospective cohort study of adults presenting to an Auckland hospital with CAP. Initial choice of antimicrobial therapy was compared to the local hospital guidelines and the British Thoracic Society (BTS), Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS) and Swedish Society of Infectious Diseases (SSID) guidelines. Results: Initial treatment in 177 patients presenting with their first episode of CAP included parenteral cephalosporin (61%), amoxycillin+clavulanate (37%), amoxycillin (2.8%) and macrolide (53%). 83/92 (90%) patients with a CURB-65 score of 0-1 were treated with a cephalosporin or amoxycillin+clavulanate. 42/85 (49%) patients with a CURB-65 score ≥ 2 were treated with a macrolide. Adherence with treatment guidelines was 97% (hospital), 53% (IDSA/ATS), 11% (BTS) and 10% (SSID). Conclusion: Initial treatment of adults with CAP adhered closely with local guidelines was discordant with the BTS and SSID guidelines.

The New Zealand Medical Journal, Aug 13, 2010

Chronic glue sniffing is known to be associated with cerebellar ataxia and wide range of biochemical abnormalities including hypokalaemia, hypocalcaemia, hypomagnesaemia, and hypophosphataemia. Rhabdomyolysis as a complication of glue sniffing probably mediated by these electrolyte disturbances i...

The New Zealand medical journal, Jan 13, 2010

The New Zealand medical journal, Jan 4, 2008

Toluene is an aromatic organic hydrocarbon, widely used as a solvent. Toluene toxicity can occur ... more Toluene is an aromatic organic hydrocarbon, widely used as a solvent. Toluene toxicity can occur from accidental or deliberate inhalation of 'glue'.

Adherence to Guidelines for Treating Community-Acquired Pneumonia at a New Zealand Hospital

Journal of Pharmacy Practice and Research, 2013

Journal of Pharmacy Practice and Research, 2013

Background: Adherence to guidelines for community-acquired pneumonia (CAP) has been shown to impr... more Background: Adherence to guidelines for community-acquired pneumonia (CAP) has been shown to improve patient outcomes and slow the emergence of antimicrobial resistance. Guidelines for treating CAP vary considerably. Aim: To determine the initial antimicrobial therapy used in hospitalised adults with CAP and to compare it with local and international CAP treatment guidelines. Method: A retrospective cohort study of adults presenting to an Auckland hospital with CAP. Initial choice of antimicrobial therapy was compared to the local hospital guidelines and the British Thoracic Society (BTS), Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS) and Swedish Society of Infectious Diseases (SSID) guidelines. Results: Initial treatment in 177 patients presenting with their first episode of CAP included parenteral cephalosporin (61%), amoxycillin+clavulanate (37%), amoxycillin (2.8%) and macrolide (53%). 83/92 (90%) patients with a CURB-65 score of 0-1 were treated with a cephalosporin or amoxycillin+clavulanate. 42/85 (49%) patients with a CURB-65 score ≥ 2 were treated with a macrolide. Adherence with treatment guidelines was 97% (hospital), 53% (IDSA/ATS), 11% (BTS) and 10% (SSID). Conclusion: Initial treatment of adults with CAP adhered closely with local guidelines was discordant with the BTS and SSID guidelines.

The New Zealand Medical Journal, Aug 13, 2010

Chronic glue sniffing is known to be associated with cerebellar ataxia and wide range of biochemical abnormalities including hypokalaemia, hypocalcaemia, hypomagnesaemia, and hypophosphataemia. Rhabdomyolysis as a complication of glue sniffing probably mediated by these electrolyte disturbances i...

The New Zealand medical journal, Jan 13, 2010

The New Zealand medical journal, Jan 4, 2008

Toluene is an aromatic organic hydrocarbon, widely used as a solvent. Toluene toxicity can occur ... more Toluene is an aromatic organic hydrocarbon, widely used as a solvent. Toluene toxicity can occur from accidental or deliberate inhalation of 'glue'.

Adherence to Guidelines for Treating Community-Acquired Pneumonia at a New Zealand Hospital

Journal of Pharmacy Practice and Research, 2013