Gregor MacDonald - Academia.edu (original) (raw)
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Papers by Gregor MacDonald
Bioorganic & medicinal …, 2010
In this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs... more In this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs. With the need to identify new hit matter for this target we applied computational techniques based on 3D shape and electrostatic similarity. Such approaches are well suited to ...
Bioorganic & medicinal …, 2010
In this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs... more In this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs. With the need to identify new hit matter for this target we applied computational techniques based on 3D shape and electrostatic similarity. Such approaches are well suited to ...