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Gregorio Rodriguez

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Research paper thumbnail of Mode decomposition and Lagrangian structures of the flow dynamics in orbitally shaken bioreactors

Physics of Fluids, 2018

In this study, two mode decomposition techniques were applied and compared to assess the flow dyn... more In this study, two mode decomposition techniques were applied and compared to assess the flow dynamics in an orbital shaken bioreactor (OSB) of cylindrical geometry and flat bottom: proper orthogonal decomposition and dynamic mode decomposition. Particle Image Velocimetry (PIV) experiments were carried out for different operating conditions including fluid height, h, and shaker rotational speed, N. A detailed flow analysis is provided for conditions when the fluid and vessel motions are in-phase (Fr = 0.23) and out-of-phase (Fr = 0.47). PIV measurements in vertical and horizontal planes were combined to reconstruct low order models of the full 3D flow and to determine its Finite-Time Lyapunov Exponent (FTLE) within OSBs. The combined results from the mode decomposition and the FTLE fields provide a useful insight into the flow dynamics and Lagrangian coherent structures in OSBs and offer a valuable tool to optimise bioprocess design in terms of mixing and cell suspension.

Research paper thumbnail of Student voice in learning assessment: a pathway not yet developed at university

RELIEVE - Revista Electrónica de Investigación y Evaluación Educativa, 2012

Research paper thumbnail of TEORÍA BÍBLICA GENERAL (II).pdf

Research paper thumbnail of Mode decomposition and Lagrangian structures of the flow dynamics in orbitally shaken bioreactors

Physics of Fluids, 2018

In this study, two mode decomposition techniques were applied and compared to assess the flow dyn... more In this study, two mode decomposition techniques were applied and compared to assess the flow dynamics in an orbital shaken bioreactor (OSB) of cylindrical geometry and flat bottom: proper orthogonal decomposition and dynamic mode decomposition. Particle Image Velocimetry (PIV) experiments were carried out for different operating conditions including fluid height, h, and shaker rotational speed, N. A detailed flow analysis is provided for conditions when the fluid and vessel motions are in-phase (Fr = 0.23) and out-of-phase (Fr = 0.47). PIV measurements in vertical and horizontal planes were combined to reconstruct low order models of the full 3D flow and to determine its Finite-Time Lyapunov Exponent (FTLE) within OSBs. The combined results from the mode decomposition and the FTLE fields provide a useful insight into the flow dynamics and Lagrangian coherent structures in OSBs and offer a valuable tool to optimise bioprocess design in terms of mixing and cell suspension.

Research paper thumbnail of Student voice in learning assessment: a pathway not yet developed at university

RELIEVE - Revista Electrónica de Investigación y Evaluación Educativa, 2012

Research paper thumbnail of TEORÍA BÍBLICA GENERAL (II).pdf

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