HARSH YADAV - Academia.edu (original) (raw)
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Papers by HARSH YADAV
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015
IJ Publication , 2023
Direct reprogramming is a very useful and interesting method for changing what happens to mature ... more Direct reprogramming is a very useful and interesting method for changing what happens to mature cells. recently This method can avoid the problems that come with using stem cells directly and allow stem cell therapy to be customized to each patient in regenerative medicine. Overexpression of different factors, like general reprogramming factors or lineage-specific transcription factors, can change what will happen to cells that have already specialized. On the other hand, biomaterials can give cells physical, topographical, and biochemical cues that can tell the cells what to do or be told what to do by the cells themselves affect the development of stem cells in a big way. Biomaterials haven't played much of a role in direct reprogramming so far, but they could be important for making direct reprogramming more precise or efficient. This review talks about how to use general direct reprogramming and biomaterials to guide stem cell differentiation.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015
IJ Publication , 2023
Direct reprogramming is a very useful and interesting method for changing what happens to mature ... more Direct reprogramming is a very useful and interesting method for changing what happens to mature cells. recently This method can avoid the problems that come with using stem cells directly and allow stem cell therapy to be customized to each patient in regenerative medicine. Overexpression of different factors, like general reprogramming factors or lineage-specific transcription factors, can change what will happen to cells that have already specialized. On the other hand, biomaterials can give cells physical, topographical, and biochemical cues that can tell the cells what to do or be told what to do by the cells themselves affect the development of stem cells in a big way. Biomaterials haven't played much of a role in direct reprogramming so far, but they could be important for making direct reprogramming more precise or efficient. This review talks about how to use general direct reprogramming and biomaterials to guide stem cell differentiation.