Haiyan Guan - Academia.edu (original) (raw)

Papers by Haiyan Guan

Research paper thumbnail of Geometric validation of a mobile laser scanning system for urban applications

2nd ISPRS International Conference on Computer Vision in Remote Sensing (CVRS 2015), 2016

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Research paper thumbnail of The p38 Mitogen-Activated Protein Kinase Regulates 11β-Hydroxysteroid Dehydrogenase Type 2 (11β-HSD2) Expression in Human Trophoblast Cells through Modulation of 11β-HSD2 Messenger Ribonucleic Acid Stability

Endocrinology, Jul 1, 2013

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Research paper thumbnail of Cadmium reduces 11 β-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells

American Journal of Physiology Endocrinology and Metabolism, 2006

... Kaiping Yang, Laura Julan, Fran Rubio, Anju Sharma, and Haiyan Guan. ... Birth Defects Res C ... more ... Kaiping Yang, Laura Julan, Fran Rubio, Anju Sharma, and Haiyan Guan. ... Birth Defects Res C Embryo Today 72: 361–370, 2004.[CrossRef][Medline]; McTernan CL, Draper N, Nicholson H, Chalder SM, Driver P, Hewison M, Kilby MD, and Stewart PM. ...

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Research paper thumbnail of Building detection from LIDAR and images in urban areas

Proceedings of Spie the International Society For Optical Engineering, Nov 1, 2007

Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An e... more Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An effective approach by the way of coarse-to-fine 3D building model generation by integration of LIDAR and multiple overlap images is proposed. Classification and segmentation can be processed by combined multi-spectral information which is provided by color aerial image and geometric information from multi-return laser scanned data. A connected graph of the segment label image has to be created to derive the neighborhood relation of the planar segments. A line segment matching, based on geometry and chromatic constraint, is applied for automatically getting the corresponding line features in multi target images. Hypotheses for polyhedral surfaces are selected using topological relations and verified using geometry.

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Research paper thumbnail of Rapid Update of Road Surface Databases Using Mobile LiDAR: Road-Markings

2013 Fifth International Conference on Geo Information Technologies For Natural Disaster Management, Oct 1, 2013

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Research paper thumbnail of Cadmium reduces 11 -hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells

Amer J Physiol Endocrinol Met, 2005

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Research paper thumbnail of Cortisol Induces Aromatase Expression in Human Placental Syncytiotrophoblasts Through the cAMP/Sp1 Pathway

Endocrinology, Feb 7, 2012

One of the dominant effects of glucocorticoids in triggering parturition in certain animal specie... more One of the dominant effects of glucocorticoids in triggering parturition in certain animal species is to drive the placental conversion of progesterone to estrogen. However, in the human placenta, estrogen is formed using dehydroepiandrosterone from the fetal adrenal glands rather than progesterone as precursor. Although aromatization of dehydroepiandrosterone is crucial in estrogen synthesis in human placenta, it is not known whether glucocorticoids affect aromatase expression. Human term placental syncytiotrophoblasts were used to examine the effect of cortisol on aromatase expression. The signaling pathway and transcription factors involved were identified in this study. Results showed that cortisol induced aromatase expression in a concentration-dependent manner, which was mediated indirectly by glucocorticoid receptor and required the participation of other proteins. The induction of aromatase by cortisol could be blocked by either specificity protein 1 (Sp1) antagonist mithramycin or knockdown of Sp1 expression. The induction of aromatase and Sp1 by cortisol could be prevented by inhibitors of the cAMP pathway, whereas activators of the cAMP pathway induced Sp1 and aromatase expression as well as Sp1 binding to aromatase promoter. Concomitantly, cortisol treatment and activation of the cAMP pathway led to increased acetylation and decreased methylation of histone 3 at the aromatase promoter. In conclusion, cortisol stimulates aromatase expression through the cAMP/Sp1 pathway in human placental syncytiotrophoblasts. These findings reveal a novel role of cortisol in increasing the local level of estrogen within the placenta that would help transform the myometrium to a contractile state, thereby contributing to a cascade of events leading to human parturition.

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Research paper thumbnail of The p38 Mitogen-Activated Protein Kinase Regulates 11-Hydroxysteroid Dehydrogenase Type 2 (11-HSD2) Expression in Human Trophoblast Cells through Modulation of 11-HSD2 Messenger Ribonucleic Acid Stability

Endocrinology, 2009

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Research paper thumbnail of 3D Reconstruction of Small-sized Cultural Relics Based on Laser Scanning and Close-range Photogrammetry

International Journal of Digital Content Technology and its Applications, 2012

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Research paper thumbnail of Learning Hierarchical Features for Automated Extraction of Road Markings From 3-D Mobile LiDAR Point Clouds

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2015

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Research paper thumbnail of Three-Dimensional Object Matching in Mobile Laser Scanning Point Clouds

IEEE Geoscience and Remote Sensing Letters, 2015

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Research paper thumbnail of Semiautomated Extraction of Street Light Poles From Mobile LiDAR Point-Clouds

IEEE Transactions on Geoscience and Remote Sensing, 2015

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Research paper thumbnail of Automated Road Information Extraction From Mobile Laser Scanning Data

IEEE Transactions on Intelligent Transportation Systems, 2015

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Research paper thumbnail of Using Mobile LiDAR Data for Rapidly Updating Road Markings

IEEE Transactions on Intelligent Transportation Systems, 2015

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Research paper thumbnail of Automated Extraction of Urban Road Facilities Using Mobile Laser Scanning Data

IEEE Transactions on Intelligent Transportation Systems, 2015

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Research paper thumbnail of Rapid Update of Road Surface Databases Using Mobile LiDAR: Road-Markings

2013 Fifth International Conference on Geo-Information Technologies for Natural Disaster Management, 2013

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Research paper thumbnail of <title>Building detection from LIDAR and images in urban areas</title>

MIPPR 2007: Pattern Recognition and Computer Vision, 2007

Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An e... more Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An effective approach by the way of coarse-to-fine 3D building model generation by integration of LIDAR and multiple overlap images is proposed. Classification and segmentation can be processed by combined multi-spectral information which is provided by color aerial image and geometric information from multi-return laser

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Research paper thumbnail of Prenatal Exposure to Bisphenol A Disrupts Mouse Fetal Liver Maturation in a Sex-Specific Manner

Journal of Cellular Biochemistry, 2015

Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals in the environment.... more Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals in the environment. Developmental exposure to BPA is known to be associated with liver dysfunction and diseases, such as hepatic steatosis, liver tumors, metabolic syndrome, and altered hepatic gene expression, and DNA methylation profiles. However, the effects of BPA on rodent liver development are unknown. The present study was undertaken to address this important question using the mouse as an experimental model. Pregnant mice were exposed to BPA via diet from embryonic day 7.5 (E7.5) to E18.5. At E18.5, fetal livers were collected, and analyzed for changes in the expression of key hepatocyte maturation markers. We found the following significant alterations in BPA-exposed female but not male fetal livers: (a) levels of the mature hepatocyte markers, albumin and glycogen synthase proteins, were decreased (-65% and -40%, respectively); (b) levels of the immature hepatocyte marker, α-fetoprotein, were increased (+43%); (c) the level of C/EBP-α protein, the master transcription factor essential for hepatocyte maturation, was down-regulated (-50%); and (d) the level of PCNA protein (marker of proliferation) was elevated (+40%), while that of caspase-3 protein and activity (markers of apoptosis) was reduced (-40% and -55%, respectively), suggestive of a perturbed balance between cell proliferation and apoptosis in BPA-exposed female fetuses. Taken together, these findings demonstrate that prenatal exposure to BPA disrupts the mouse fetal liver maturation in a sex-specific manner, and suggest a fetal origin for BPA-induced hepatic dysfunction and diseases.

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Research paper thumbnail of Vehicle Detection in High-Resolution Aerial Images via Sparse Representation and Superpixels

IEEE Transactions on Geoscience and Remote Sensing, 2015

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Research paper thumbnail of Automatic extraction of power lines from mobile laser scanning data

2014 IEEE Geoscience and Remote Sensing Symposium, 2014

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Research paper thumbnail of Geometric validation of a mobile laser scanning system for urban applications

2nd ISPRS International Conference on Computer Vision in Remote Sensing (CVRS 2015), 2016

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Research paper thumbnail of The p38 Mitogen-Activated Protein Kinase Regulates 11β-Hydroxysteroid Dehydrogenase Type 2 (11β-HSD2) Expression in Human Trophoblast Cells through Modulation of 11β-HSD2 Messenger Ribonucleic Acid Stability

Endocrinology, Jul 1, 2013

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Research paper thumbnail of Cadmium reduces 11 β-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells

American Journal of Physiology Endocrinology and Metabolism, 2006

... Kaiping Yang, Laura Julan, Fran Rubio, Anju Sharma, and Haiyan Guan. ... Birth Defects Res C ... more ... Kaiping Yang, Laura Julan, Fran Rubio, Anju Sharma, and Haiyan Guan. ... Birth Defects Res C Embryo Today 72: 361–370, 2004.[CrossRef][Medline]; McTernan CL, Draper N, Nicholson H, Chalder SM, Driver P, Hewison M, Kilby MD, and Stewart PM. ...

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Research paper thumbnail of Building detection from LIDAR and images in urban areas

Proceedings of Spie the International Society For Optical Engineering, Nov 1, 2007

Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An e... more Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An effective approach by the way of coarse-to-fine 3D building model generation by integration of LIDAR and multiple overlap images is proposed. Classification and segmentation can be processed by combined multi-spectral information which is provided by color aerial image and geometric information from multi-return laser scanned data. A connected graph of the segment label image has to be created to derive the neighborhood relation of the planar segments. A line segment matching, based on geometry and chromatic constraint, is applied for automatically getting the corresponding line features in multi target images. Hypotheses for polyhedral surfaces are selected using topological relations and verified using geometry.

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Research paper thumbnail of Rapid Update of Road Surface Databases Using Mobile LiDAR: Road-Markings

2013 Fifth International Conference on Geo Information Technologies For Natural Disaster Management, Oct 1, 2013

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Research paper thumbnail of Cadmium reduces 11 -hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells

Amer J Physiol Endocrinol Met, 2005

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Cortisol Induces Aromatase Expression in Human Placental Syncytiotrophoblasts Through the cAMP/Sp1 Pathway

Endocrinology, Feb 7, 2012

One of the dominant effects of glucocorticoids in triggering parturition in certain animal specie... more One of the dominant effects of glucocorticoids in triggering parturition in certain animal species is to drive the placental conversion of progesterone to estrogen. However, in the human placenta, estrogen is formed using dehydroepiandrosterone from the fetal adrenal glands rather than progesterone as precursor. Although aromatization of dehydroepiandrosterone is crucial in estrogen synthesis in human placenta, it is not known whether glucocorticoids affect aromatase expression. Human term placental syncytiotrophoblasts were used to examine the effect of cortisol on aromatase expression. The signaling pathway and transcription factors involved were identified in this study. Results showed that cortisol induced aromatase expression in a concentration-dependent manner, which was mediated indirectly by glucocorticoid receptor and required the participation of other proteins. The induction of aromatase by cortisol could be blocked by either specificity protein 1 (Sp1) antagonist mithramycin or knockdown of Sp1 expression. The induction of aromatase and Sp1 by cortisol could be prevented by inhibitors of the cAMP pathway, whereas activators of the cAMP pathway induced Sp1 and aromatase expression as well as Sp1 binding to aromatase promoter. Concomitantly, cortisol treatment and activation of the cAMP pathway led to increased acetylation and decreased methylation of histone 3 at the aromatase promoter. In conclusion, cortisol stimulates aromatase expression through the cAMP/Sp1 pathway in human placental syncytiotrophoblasts. These findings reveal a novel role of cortisol in increasing the local level of estrogen within the placenta that would help transform the myometrium to a contractile state, thereby contributing to a cascade of events leading to human parturition.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of The p38 Mitogen-Activated Protein Kinase Regulates 11-Hydroxysteroid Dehydrogenase Type 2 (11-HSD2) Expression in Human Trophoblast Cells through Modulation of 11-HSD2 Messenger Ribonucleic Acid Stability

Endocrinology, 2009

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Research paper thumbnail of 3D Reconstruction of Small-sized Cultural Relics Based on Laser Scanning and Close-range Photogrammetry

International Journal of Digital Content Technology and its Applications, 2012

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Learning Hierarchical Features for Automated Extraction of Road Markings From 3-D Mobile LiDAR Point Clouds

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Three-Dimensional Object Matching in Mobile Laser Scanning Point Clouds

IEEE Geoscience and Remote Sensing Letters, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Semiautomated Extraction of Street Light Poles From Mobile LiDAR Point-Clouds

IEEE Transactions on Geoscience and Remote Sensing, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Automated Road Information Extraction From Mobile Laser Scanning Data

IEEE Transactions on Intelligent Transportation Systems, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Using Mobile LiDAR Data for Rapidly Updating Road Markings

IEEE Transactions on Intelligent Transportation Systems, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Automated Extraction of Urban Road Facilities Using Mobile Laser Scanning Data

IEEE Transactions on Intelligent Transportation Systems, 2015

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Research paper thumbnail of Rapid Update of Road Surface Databases Using Mobile LiDAR: Road-Markings

2013 Fifth International Conference on Geo-Information Technologies for Natural Disaster Management, 2013

Bookmarks Related papers MentionsView impact

Research paper thumbnail of <title>Building detection from LIDAR and images in urban areas</title>

MIPPR 2007: Pattern Recognition and Computer Vision, 2007

Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An e... more Rapid texture mapping of buildings is a key aspect for reconstruction of 3D city landscapes. An effective approach by the way of coarse-to-fine 3D building model generation by integration of LIDAR and multiple overlap images is proposed. Classification and segmentation can be processed by combined multi-spectral information which is provided by color aerial image and geometric information from multi-return laser

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Prenatal Exposure to Bisphenol A Disrupts Mouse Fetal Liver Maturation in a Sex-Specific Manner

Journal of Cellular Biochemistry, 2015

Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals in the environment.... more Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals in the environment. Developmental exposure to BPA is known to be associated with liver dysfunction and diseases, such as hepatic steatosis, liver tumors, metabolic syndrome, and altered hepatic gene expression, and DNA methylation profiles. However, the effects of BPA on rodent liver development are unknown. The present study was undertaken to address this important question using the mouse as an experimental model. Pregnant mice were exposed to BPA via diet from embryonic day 7.5 (E7.5) to E18.5. At E18.5, fetal livers were collected, and analyzed for changes in the expression of key hepatocyte maturation markers. We found the following significant alterations in BPA-exposed female but not male fetal livers: (a) levels of the mature hepatocyte markers, albumin and glycogen synthase proteins, were decreased (-65% and -40%, respectively); (b) levels of the immature hepatocyte marker, α-fetoprotein, were increased (+43%); (c) the level of C/EBP-α protein, the master transcription factor essential for hepatocyte maturation, was down-regulated (-50%); and (d) the level of PCNA protein (marker of proliferation) was elevated (+40%), while that of caspase-3 protein and activity (markers of apoptosis) was reduced (-40% and -55%, respectively), suggestive of a perturbed balance between cell proliferation and apoptosis in BPA-exposed female fetuses. Taken together, these findings demonstrate that prenatal exposure to BPA disrupts the mouse fetal liver maturation in a sex-specific manner, and suggest a fetal origin for BPA-induced hepatic dysfunction and diseases.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Vehicle Detection in High-Resolution Aerial Images via Sparse Representation and Superpixels

IEEE Transactions on Geoscience and Remote Sensing, 2015

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Automatic extraction of power lines from mobile laser scanning data

2014 IEEE Geoscience and Remote Sensing Symposium, 2014

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