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Papers by Hajar EL AGOURI
Visual journal of emergency medicine, Apr 1, 2024
Digestive Diseases, 2014
In this paper, we will discuss the nuances of pediatric eosinophilic esophagitis based on symptom... more In this paper, we will discuss the nuances of pediatric eosinophilic esophagitis based on symptoms, diagnostics and therapy. The diagnostics will include endoscopy, histology and anesthesia. Therapeutics will include the diet, drugs and ‘distress'. Future directions in terms of clinical presentation and diagnostics will be discussed and important issues such as repeated exposure to anesthetic agents and effects of therapy on growth and psychological distress will be listed.
Research Square (Research Square), Aug 31, 2021
PAMJ clinical medicine, 2022
International journal of clinical studies and medical case reports, Jan 31, 2022
International Journal of Clinical Studies and Medical Case Reports
Annales d'Endocrinologie, 2021
BMC Gastroenterology, Jun 5, 2023
PAMJ clinical medicine, 2022
BMC Research Notes, Feb 19, 2022
Tumori Journal, 2020
Introduction: Apocrine carcinoma of breast is a rare type of malignant tumor, the incidence of wh... more Introduction: Apocrine carcinoma of breast is a rare type of malignant tumor, the incidence of which varies between 0.3 - 0.4 % of all female breast cancers.Apocrine carcinoma is exceptional in male patients and very few cases have been described in literature. This tumor shows distinct microscopic and immunohistological features. We report an exceptional observation of apocrine carcinoma of breast in a man. Patient and observation: He’s a 54 years old man who had for 2months a painless nodule at the left axillary..The patient had family history of breast and prostate cancers. Physical examination revealed a left axilary lymphadenopathy movable relative to superficial and deep plans with no evidence mass of breasts. MRI of the breast was performed and revealed a mass that was 38 x 10 mm in size.A biopsy of the lymphadenopathy was performed. It objectified a carcinomatous proliferation. An immunohistochemical study showed that tumor cells express Her 2, but do not express estrogenic ...
International Journal of Scientific Reports
This article discusses the rare clinical situation where cervical cancer mimics the symptoms of a... more This article discusses the rare clinical situation where cervical cancer mimics the symptoms of a cervical myoma. Cervical cancer is a prevalent cancer in women, often caused by HPV infection, and can cause symptoms such as abnormal vaginal bleeding and pain during sexual intercourse. However, cervical myoma can also cause similar symptoms, making it difficult to differentiate between the two conditions. Delayed diagnosis and treatment of cervical cancer can lead to a poorer outcome for patients, highlighting the importance of accurately identifying the disease. Healthcare professionals should be aware of this rare clinical situation and conduct thorough examinations to differentiate between cervical cancer and cervical myoma. Early diagnosis and appropriate treatment can improve the prognosis for patients with this disease. Women should also be aware of the potential symptoms of cervical cancer and consult a healthcare professional if they experience abnormal vaginal bleeding or pa...
BMC Gastroenterology
Background Advances in molecular biology have improved understanding of the molecular features of... more Background Advances in molecular biology have improved understanding of the molecular features of carcinogenesis and progression of colorectal cancer. It is clear that the efficacy of anti-EGFR depends upon the RAS mutational status, since any mutation in RAS is associated with resistance to anti-EGFR therapy. The aim of this study is to report the largest North African description of KRAS and NRAS status in metastatic colorectal cancer and to describe the association of these mutations with clinicopathological characteristics. Methods This is a prospective study of all consecutive unselected metastatic colorectal cancer samples, collected from the Laboratory of Pathology at the National Institute of Oncology of Rabat, Morocco, from January 1st 2020 to December 31st 2021. The molecular analysis was performed on the Idylla™ platform (fully automated real-time polymerase chain reaction-based assay) for KRAS and NRAS mutations in exons 2, 3 and 4. These mutations were correlated to gen...
International journal of clinical studies and medical case reports, Jan 31, 2022
Journal of Personalized Medicine
Breast cancer is one of the main global priorities in terms of public health. It remains the most... more Breast cancer is one of the main global priorities in terms of public health. It remains the most frequent cancer in women and is the leading cause of their death. The human microbiome plays various roles in maintaining health by ensuring a dynamic balance with the host or in the appearance of various pathologies including breast cancer. In this study, we performed an analysis of bacterial signature differences between tumor and adjacent tissues of breast cancer patients in Morocco. Using 16S rRNA gene sequencing, we observed that adjacent tissue contained a much higher percentage of the Gammaproteobacteria class (35.7%) while tumor tissue was characterized by a higher percentage of Bacilli and Actinobacteria classes, with about 18.8% and 17.2% average abundance, respectively. Analysis of tumor subtype revealed enrichment of genus Sphingomonodas in TNBC while Sphingomonodas was predominant in HER2. The LEfSe and the genus level heatmap analysis revealed a higher abundance of the Rot...
Saudi journal of pathology and microbiology, Apr 25, 2022
Annals of Cancer Research and Therapy
Visual journal of emergency medicine, Apr 1, 2024
Digestive Diseases, 2014
In this paper, we will discuss the nuances of pediatric eosinophilic esophagitis based on symptom... more In this paper, we will discuss the nuances of pediatric eosinophilic esophagitis based on symptoms, diagnostics and therapy. The diagnostics will include endoscopy, histology and anesthesia. Therapeutics will include the diet, drugs and ‘distress'. Future directions in terms of clinical presentation and diagnostics will be discussed and important issues such as repeated exposure to anesthetic agents and effects of therapy on growth and psychological distress will be listed.
Research Square (Research Square), Aug 31, 2021
PAMJ clinical medicine, 2022
International journal of clinical studies and medical case reports, Jan 31, 2022
International Journal of Clinical Studies and Medical Case Reports
Annales d'Endocrinologie, 2021
BMC Gastroenterology, Jun 5, 2023
PAMJ clinical medicine, 2022
BMC Research Notes, Feb 19, 2022
Tumori Journal, 2020
Introduction: Apocrine carcinoma of breast is a rare type of malignant tumor, the incidence of wh... more Introduction: Apocrine carcinoma of breast is a rare type of malignant tumor, the incidence of which varies between 0.3 - 0.4 % of all female breast cancers.Apocrine carcinoma is exceptional in male patients and very few cases have been described in literature. This tumor shows distinct microscopic and immunohistological features. We report an exceptional observation of apocrine carcinoma of breast in a man. Patient and observation: He’s a 54 years old man who had for 2months a painless nodule at the left axillary..The patient had family history of breast and prostate cancers. Physical examination revealed a left axilary lymphadenopathy movable relative to superficial and deep plans with no evidence mass of breasts. MRI of the breast was performed and revealed a mass that was 38 x 10 mm in size.A biopsy of the lymphadenopathy was performed. It objectified a carcinomatous proliferation. An immunohistochemical study showed that tumor cells express Her 2, but do not express estrogenic ...
International Journal of Scientific Reports
This article discusses the rare clinical situation where cervical cancer mimics the symptoms of a... more This article discusses the rare clinical situation where cervical cancer mimics the symptoms of a cervical myoma. Cervical cancer is a prevalent cancer in women, often caused by HPV infection, and can cause symptoms such as abnormal vaginal bleeding and pain during sexual intercourse. However, cervical myoma can also cause similar symptoms, making it difficult to differentiate between the two conditions. Delayed diagnosis and treatment of cervical cancer can lead to a poorer outcome for patients, highlighting the importance of accurately identifying the disease. Healthcare professionals should be aware of this rare clinical situation and conduct thorough examinations to differentiate between cervical cancer and cervical myoma. Early diagnosis and appropriate treatment can improve the prognosis for patients with this disease. Women should also be aware of the potential symptoms of cervical cancer and consult a healthcare professional if they experience abnormal vaginal bleeding or pa...
BMC Gastroenterology
Background Advances in molecular biology have improved understanding of the molecular features of... more Background Advances in molecular biology have improved understanding of the molecular features of carcinogenesis and progression of colorectal cancer. It is clear that the efficacy of anti-EGFR depends upon the RAS mutational status, since any mutation in RAS is associated with resistance to anti-EGFR therapy. The aim of this study is to report the largest North African description of KRAS and NRAS status in metastatic colorectal cancer and to describe the association of these mutations with clinicopathological characteristics. Methods This is a prospective study of all consecutive unselected metastatic colorectal cancer samples, collected from the Laboratory of Pathology at the National Institute of Oncology of Rabat, Morocco, from January 1st 2020 to December 31st 2021. The molecular analysis was performed on the Idylla™ platform (fully automated real-time polymerase chain reaction-based assay) for KRAS and NRAS mutations in exons 2, 3 and 4. These mutations were correlated to gen...
International journal of clinical studies and medical case reports, Jan 31, 2022
Journal of Personalized Medicine
Breast cancer is one of the main global priorities in terms of public health. It remains the most... more Breast cancer is one of the main global priorities in terms of public health. It remains the most frequent cancer in women and is the leading cause of their death. The human microbiome plays various roles in maintaining health by ensuring a dynamic balance with the host or in the appearance of various pathologies including breast cancer. In this study, we performed an analysis of bacterial signature differences between tumor and adjacent tissues of breast cancer patients in Morocco. Using 16S rRNA gene sequencing, we observed that adjacent tissue contained a much higher percentage of the Gammaproteobacteria class (35.7%) while tumor tissue was characterized by a higher percentage of Bacilli and Actinobacteria classes, with about 18.8% and 17.2% average abundance, respectively. Analysis of tumor subtype revealed enrichment of genus Sphingomonodas in TNBC while Sphingomonodas was predominant in HER2. The LEfSe and the genus level heatmap analysis revealed a higher abundance of the Rot...
Saudi journal of pathology and microbiology, Apr 25, 2022
Annals of Cancer Research and Therapy