Harkirat Kaur - Academia.edu (original) (raw)

Papers by Harkirat Kaur

Research paper thumbnail of Experimental assessment of nanoclay effect on hardness, tensile and flexural properties of glass fiber/epoxy laminates

Materials Today: Proceedings

Research paper thumbnail of Cardiotoxicity Associated With Chimeric Antigen Receptor (CAR)-T Cell Therapy for Hematologic Malignancies: A Systematic Review

Cureus

Chimeric Antigen Receptor (CAR)-T cell therapy has been one of the most important breakthroughs f... more Chimeric Antigen Receptor (CAR)-T cell therapy has been one of the most important breakthroughs for treating hematologic malignancies. On the other hand, the therapy had many toxicities. One of the toxicities of the CART therapy is cardiotoxicity. The goal of the systematic review is to elaborate on the cardiotoxicities related to CART therapy for hematologic malignancies. The systematic review is following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) 2020 guidelines. The systematic search was done using PubMed, PubMed Central (PMC), Google Scholar, Cochrane Library, ScienceDirect, and clinicaltrial.gov. The search and selection of studies were done on April 28, 2022, and May 6, 2022, respectively. The studies were selected based upon participants, intervention, and outcomes (PIO) elements and the articles that were included were, full-text articles published within the last ten years, clinical trials, meta-analyses, randomized controlled trial, review, and systematic review. The exclusion criteria were non-hematologic malignancy, non-English-language articles. The initial search had 2,159 publications. The publications were assessed with assessment tools of Scale of the Assessment of Narrative Review Articles (SANRA), Newcastle-Ottawa Scale (NCOS), and Cochrane Collaboration Risk of Bias Tool (CCRBT), which led to selection of eight publications. The systematic review concludes that cardiotoxicity happened in adults and pediatric patients receiving the CART cell therapy and that those cardiac adverse events had many risk factors. Therefore, monitoring these cardiotoxicities is highly essential.

Research paper thumbnail of The Role of Gut-Microbiota in the Pathophysiology and Therapy of Irritable Bowel Syndrome: A Systematic Review

Cureus

Irritable Bowel Syndrome (IBS) is one of the most prevalent chronic gastrointestinal diseases, wh... more Irritable Bowel Syndrome (IBS) is one of the most prevalent chronic gastrointestinal diseases, which is characterized by recurrent abdominal pain and altered bowel habits. The pathophysiological mechanisms are not completely clear for IBS, multiple factors such as genetic, psychosocial, environmental, visceral hypersensitivity, low-grade inflammation, gastrointestinal motility changes, food components, and intestinal microbiota are thought to play a role in the disease process of IBS. The rapid progression of recent microbiome research using advanced microbiological technologies has shed light on dysbiosis related to the pathophysiology of IBS. We used PubMed, PubMed Central, and Medline as our primary databases to search for articles using keywords and medical subject heading (MeSH) keywords on April 30, 2022, to render a total of 4062 articles. Then, a total of 10 articles were selected following a quality assessment. Despite the variable findings in different studies, most studies have concluded that IBS patients have a reduction in bacterial diversity and an increase in the temporal instability of the microbiota. IBS is known as a stress disorder, and the gut-microbiome-brain axis has been associated with the pathogenesis of the disease. Additionally, the potential of dietary manipulation of gut microbiota and the use of probiotics, prebiotics, and synbiotics in the treatment of IBS has been studied in recent years and shown promising results. We concluded that the gut microbiome plays a substantial role in the pathophysiology of IBS.

Research paper thumbnail of The Efficacy of Bezlotoxumab in the Prevention of Recurrent Clostridium difficile: A Systematic Review

Cureus

Clostridium difficile infection (CDI) is the most common nosocomial infection in hospitals. Despi... more Clostridium difficile infection (CDI) is the most common nosocomial infection in hospitals. Despite the fact that CDI has treatment options, recurrence is common after the treatment, recurrence will occur in approximately 20%-35% of people initially affected, with 40%-60% of these having a second recurrence. Patients are more likely to have several recurrences after the second, which can lead to antibiotic overuse, and as a result, CDI-related health care expenses, hospitalizations, and mortality are on the rise. The first treatment to receive Food and Drug Administration (FDA) approval for the prevention of C. difficile recurrence is bezlotoxumab, a novel human monoclonal antibody against C. difficile toxin B. In the present systematic review, we assessed various studies from PubMed, PubMed Central (PMC), Google Scholar, and Science direct that evaluated the efficacy of bezlotoxumab in the prevention of recurrent C. difficile (rCDI), and we also briefly discussed the pathophysiology of C. difficile and the risk factors for recurrence of C. difficile. The major MODIFY trial has proven the efficacy, pooled analysis of MODIFY 1 AND 2 trials demonstrated the following results as compared to placebo (bezlotoxumab: 129/781 [16.5] placebo:206/773 [26.6]-10.0% [95% CI-14.0 to-6.0], p<0.0001) with number needed to treat (NNT) of 10. All other observational studies also showed a positive response with bezlotoxumab in the prevention of C. difficile. In conclusion, bezlotoxumab is a great option adjunctive with standard of care CDI antibiotics for the prevention of rCDI in high-risk adults.

Research paper thumbnail of Silk fibroin: a promising bio-material for the treatment of heavy metal-contaminated water, adsorption isotherms, kinetics, and mechanism

Environmental Science and Pollution Research

Silk is the strongest natural biopolymer produced by silk worms possessing superior adsorbent pro... more Silk is the strongest natural biopolymer produced by silk worms possessing superior adsorbent properties and thus extensively used in various applications. The present study involved the preparation of powder form of a silk fibroin materials and their application in adsorption of heavy metals, particularly, iron from aqueous solution. The morphological and structural characteristic properties of this promising materials were examined by using different analytical techniques. Batch experiments were conducted within feasible parametric ranges to understand the effect of dose, time, concentration, pH, and reusability. Silk fibroin was effective for iron adsorption over a wide range of pH 6 to 10. The adsorption removal efficiency of 98% was attained for removal of iron from contaminated water at moderate dose of 0.25 g and contact time of 60 min, which is unprecedented by considering the environment benign nature of the material. The data was examined in different isotherm models wherein it fitted best in Langmuir adsorption model. Similarly, Langmuir isotherm model, with R2 value of 0.984 and KL 0.412 and maximum adsorption capacity as 12.82 mg g−1, suggests monolayer adsorption. Kinetic study with better R2 value of 0.941 represented the pseudo-second order kinetics governed by the chemisorption reaction. To understand the practical applicability of silk fibroin, the repeatability study up to 5 cycles were performed. The findings are very encouraging which confirmed the usage of silk fibroin as adsorbent for multiple cycles with marginal decrease in adsorption efficiency. Eventually, the material was tested for iron removal in real contaminated water which revealed its potential and selectivity for removal of iron in different matrix.

Research paper thumbnail of Non-Destructive testing to detect multiple cracks in reinforced concrete beam using electromechanical impedance technique

Materials Today: Proceedings

Research paper thumbnail of Nanofluids: A Review Preparation, Stability, Properties and Applications

International journal of engineering research and technology, 2016

Nanofluids, suspension of nano sized particles having higher conductivity than base fluid, has re... more Nanofluids, suspension of nano sized particles having higher conductivity than base fluid, has reported many interesting properties which gains the attention of researchers and proved vital in many applications. This document is a review article on nanofluids. The article provides the basic information about nanofluids, their preparation methods, stability analyses, thermophysical properties and applications. Also discusses the future scope of nanofluids. Keywords—nanofluids; nanofluids preparation; stability; thermophsical properties;

Research paper thumbnail of B.Sc. (Hons.) Nursing Entrance Examination - 2010

Research paper thumbnail of A Logic gate based Double Talk Detector for Acoustic Echo Cancellation

The occurrence of echo is one of the major problems faced by hands free telephone systems. Acoust... more The occurrence of echo is one of the major problems faced by hands free telephone systems. Acoustic echo cancellers (AEC) are used to improve the quality of speech by removing echo. Adaptive filters make it possible to cancel the echo after estimating it. Double talk occurs when both far and near speakers are activating simultaneously, results into the divergence of adaptive filter. Double talk detectors based on decision parameter calculation and comparing with threshold are used to freeze the filter adaptation during double talk periods. These detectors miss some double talks and increase the residual error. In this paper, we present a new way of detecting double talk using logic AND gate so that missed detection rate decreases and acoustic echo canceller performance improves.

Research paper thumbnail of Global Capitalism and Its Impact on Education in English Language

This article is going to examine the surfacing of a new stage of global capitalism, called inform... more This article is going to examine the surfacing of a new stage of global capitalism, called informationalism (a term coined by Castells), and its consequences f or English language teaching, with its focal point resting on three cru cial issues. First, how globalization has resulted in the further spread of English as an int ernational language and how there is a shift of authority from the native to the nonnative speak ers of the language. Second, how the economic and employment trends today are changing t he way English is used with special reference to nonnative speakers who need to use the English language daily for international collaborations and negotiations, presenting intrica te ideas, and critical explanation of rapidly changing information. Finally, how new info rmation technologies which are transforming the notions of literacy and are making on- line navigation and research, interpretation and understanding of hypermedia, and synchronous and asynchronous on-line communic...

Research paper thumbnail of A Study of Spirometric Lung Function Tets and Its Correlation with High Resolution Computed Tomography in Patients of Rheumatoid Arthritis

Journal of Evolution of medical and Dental Sciences, 2013

Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis of... more Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis often with non specific systemic symptoms. Pleuropulmonary involvement is a important cause of morbidity and mortality in patients of rheumatoid arthritis. The extra articular manifestations like bronchiectasis, interstitial lung disease, caplan syndrome are well known complications of rheumatoid arthritis 1 . To make these things more clear, the present study has was conducted enrolling 50 patients of rheumatoid arthritis coming to Medicine Department of Sri Guru

Research paper thumbnail of New Teaching Methodologies

Research paper thumbnail of Treatment methods for removal of pharmaceuticals and personal care products from domestic wastewater

Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology, 2019

Abstract Rapid urbanization and overuse of pharmaceuticals and personal care products has resulte... more Abstract Rapid urbanization and overuse of pharmaceuticals and personal care products has resulted in their occurrence in water bodies and wastewater streams worldwide. In the past few years, high concentrations of antibiotics, analgesics, antiepileptics, and antimicrobial agents have been detected in Indian rivers and domestic effluents as well. Despite trace concentrations, these micropollutants escape conventional treatment systems and find their way in effluents of sewage treatment plants. This is attributed to certain properties such as log Kow, water solubility, nonbiodegradability, etc. In order to address these shortcomings, functionalized adsorbents and various advanced treatment methods such as ozonation, membrane processes, and advanced photocatalytic materials have been developed. In this chapter a comparison of state of the art treatment methods has been done and their shortcomings have been discussed. Future research directions have also been suggested.

Research paper thumbnail of Enhancement of Immunity and Health in Neonates and Infants

Journal of Neonatology, 2021

Immunity is protective mechanism of the body against infection, diseases, and cancers. The strong... more Immunity is protective mechanism of the body against infection, diseases, and cancers. The stronger the immunity is the healthier we are. With increasing environmental change worldwide, increase of new emerging diseases and infection over last few decades, it has become imperative to move toward prevention more than the treatment. The immune mechanism in pediatric population especially neonates and infants is much different than adults and is yet evolving. The development of immunity starts in utero and is dependent on several factors. The various efforts to improve immunity and health should start from antenatal period focusing on overall health and nutrition of mother. Maternal nutrition, antenatal steroids, and delayed cord clamping are helpful in decreasing various neonatal morbidities which include respiratory distress syndrome, sepsis, necrotizing enterocolitis, intraventricular hemorrhage, and mortality. After birth during initial 6 months, exclusive breastfeeding, growth mon...

Research paper thumbnail of Enhanced photocatalytic degradation of antimicrobial triclosan using rGO–TiO2 composite under natural solar illumination

Journal of Materials Science: Materials in Electronics, 2020

In the present study, the enhancement in the photocatalytic degradation of triclosan after incorp... more In the present study, the enhancement in the photocatalytic degradation of triclosan after incorporation of reduced graphene oxide (rGO) in pristine TiO 2 is investigated. Triclosan is an antimicrobial compound found in commonly used personal care products. The study involved the synthesis of reduced graphene oxide-titania composite using the improved Hummer and hydrothermal methods. The optimum rGO content in the composite was found to be 10 wt% (RT10). The composite was characterized using X-ray diffraction (XRD), Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), UV-Vis spectroscopy, Scanning electron microscopy (SEM), and Brunauer-Emmett-Teller surface area (BETSA). The experimental conditions viz. catalyst dose, initial triclosan concentration, and solution pH were studied. The surface area of the composite was substantially higher than either of TiO 2 and GO. The photocatalytic reaction followed pseudo-first-order kinetics with the highest rate constant of 0.251 h −1 obtained for RT10. The scavenging experiment indicated the role of hydroxyl radical in the degradation mechanism. The composite displayed efficient degradation under natural sunlight attributed to narrowing of band gap. It also performed effectively in secondary effluent containing triclosan despite matrix effect. Thus, the composite has potential application as a promising photocatalyst in tertiary treatment of water and wastewater.

Research paper thumbnail of Neonatal COVID-19 Infection Management

Journal of Neonatology, 2020

Coronavirus disease 19 (COVID-19) infection pandemic has affected remarkable morbidity and mortal... more Coronavirus disease 19 (COVID-19) infection pandemic has affected remarkable morbidity and mortality in a very short span of time. The overall disease profile and epidemiology is yet evolving but it seems to be highly infectious. Perinatal coronavirus infection is altogether a different perspective which has to be taken care of in a different way.

Research paper thumbnail of Teratocarcinosarcoma of the Nasal and Maxillary Sinus Mass- a Rare Case

Journal of Evolution of Medical and Dental Sciences, 2019

A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on p... more A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on pain in the eyes and headache and progress to nasal mass within period of 3 months. Routine haematological and biochemical investigations were done, which were normal at the time of presentation. Nasal endoscopy was done which showed nasal mass which bleeds on touch. A computed tomography (CT) scan face and neck revealed an inhomogenously enhancing soft tissue density lesion measuring 5.7*3.3*3.9 cm involving left maxillary sinus extending to left ethmoid sinus, left nasal cavity reaching up to posterior choana abutting the nasal septum (Figure 1).

Research paper thumbnail of Incidental finding of pulmonary lymphangitis carcinomatosa in a patient of chest trauma

Indian Journal of Anaesthesia, 2019

70 Indian Journal of Anaesthesia | Volume 63 | Issue 1 | January 2019 This is an open access jour... more 70 Indian Journal of Anaesthesia | Volume 63 | Issue 1 | January 2019 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‐NonCommercial‐ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‐commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. How to cite this article: Singh S, Lalin D, Verma VK. Management of local anaesthetic systemic toxicity by timely lipid resuscitation in a paraturient ‐ A case report. Indian J Anaesth 2019;63:68‐70. © 2019 Indian Journal of Anaesthesia | Published by Wolters Kluwer ‐ Medknow Access this article online

Research paper thumbnail of Migration of Students- A Comparative Study among Different Countries of the World

International Journal of Trend in Scientific Research and Development, 2019

Going abroad has now become trend for the youngsters mainly in India. Students go abroad for thei... more Going abroad has now become trend for the youngsters mainly in India. Students go abroad for their higher education and majority of them stays there and don't come back. The reason for not coming back can be influenced by many factors like: the living standard in the foreign countries, the method of education, the earnings etc. This paper shows the statistical data of the students going abroad from India for higher education as well as the students coming to India for further education and its comparison with the past years. This paper will also examine the various factors which influence the students to go abroad for further education.

Research paper thumbnail of Biomimetic lipophilic activated carbon for enhanced removal of triclosan from water

Journal of Colloid and Interface Science, 2019

Research paper thumbnail of Experimental assessment of nanoclay effect on hardness, tensile and flexural properties of glass fiber/epoxy laminates

Materials Today: Proceedings

Research paper thumbnail of Cardiotoxicity Associated With Chimeric Antigen Receptor (CAR)-T Cell Therapy for Hematologic Malignancies: A Systematic Review

Cureus

Chimeric Antigen Receptor (CAR)-T cell therapy has been one of the most important breakthroughs f... more Chimeric Antigen Receptor (CAR)-T cell therapy has been one of the most important breakthroughs for treating hematologic malignancies. On the other hand, the therapy had many toxicities. One of the toxicities of the CART therapy is cardiotoxicity. The goal of the systematic review is to elaborate on the cardiotoxicities related to CART therapy for hematologic malignancies. The systematic review is following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) 2020 guidelines. The systematic search was done using PubMed, PubMed Central (PMC), Google Scholar, Cochrane Library, ScienceDirect, and clinicaltrial.gov. The search and selection of studies were done on April 28, 2022, and May 6, 2022, respectively. The studies were selected based upon participants, intervention, and outcomes (PIO) elements and the articles that were included were, full-text articles published within the last ten years, clinical trials, meta-analyses, randomized controlled trial, review, and systematic review. The exclusion criteria were non-hematologic malignancy, non-English-language articles. The initial search had 2,159 publications. The publications were assessed with assessment tools of Scale of the Assessment of Narrative Review Articles (SANRA), Newcastle-Ottawa Scale (NCOS), and Cochrane Collaboration Risk of Bias Tool (CCRBT), which led to selection of eight publications. The systematic review concludes that cardiotoxicity happened in adults and pediatric patients receiving the CART cell therapy and that those cardiac adverse events had many risk factors. Therefore, monitoring these cardiotoxicities is highly essential.

Research paper thumbnail of The Role of Gut-Microbiota in the Pathophysiology and Therapy of Irritable Bowel Syndrome: A Systematic Review

Cureus

Irritable Bowel Syndrome (IBS) is one of the most prevalent chronic gastrointestinal diseases, wh... more Irritable Bowel Syndrome (IBS) is one of the most prevalent chronic gastrointestinal diseases, which is characterized by recurrent abdominal pain and altered bowel habits. The pathophysiological mechanisms are not completely clear for IBS, multiple factors such as genetic, psychosocial, environmental, visceral hypersensitivity, low-grade inflammation, gastrointestinal motility changes, food components, and intestinal microbiota are thought to play a role in the disease process of IBS. The rapid progression of recent microbiome research using advanced microbiological technologies has shed light on dysbiosis related to the pathophysiology of IBS. We used PubMed, PubMed Central, and Medline as our primary databases to search for articles using keywords and medical subject heading (MeSH) keywords on April 30, 2022, to render a total of 4062 articles. Then, a total of 10 articles were selected following a quality assessment. Despite the variable findings in different studies, most studies have concluded that IBS patients have a reduction in bacterial diversity and an increase in the temporal instability of the microbiota. IBS is known as a stress disorder, and the gut-microbiome-brain axis has been associated with the pathogenesis of the disease. Additionally, the potential of dietary manipulation of gut microbiota and the use of probiotics, prebiotics, and synbiotics in the treatment of IBS has been studied in recent years and shown promising results. We concluded that the gut microbiome plays a substantial role in the pathophysiology of IBS.

Research paper thumbnail of The Efficacy of Bezlotoxumab in the Prevention of Recurrent Clostridium difficile: A Systematic Review

Cureus

Clostridium difficile infection (CDI) is the most common nosocomial infection in hospitals. Despi... more Clostridium difficile infection (CDI) is the most common nosocomial infection in hospitals. Despite the fact that CDI has treatment options, recurrence is common after the treatment, recurrence will occur in approximately 20%-35% of people initially affected, with 40%-60% of these having a second recurrence. Patients are more likely to have several recurrences after the second, which can lead to antibiotic overuse, and as a result, CDI-related health care expenses, hospitalizations, and mortality are on the rise. The first treatment to receive Food and Drug Administration (FDA) approval for the prevention of C. difficile recurrence is bezlotoxumab, a novel human monoclonal antibody against C. difficile toxin B. In the present systematic review, we assessed various studies from PubMed, PubMed Central (PMC), Google Scholar, and Science direct that evaluated the efficacy of bezlotoxumab in the prevention of recurrent C. difficile (rCDI), and we also briefly discussed the pathophysiology of C. difficile and the risk factors for recurrence of C. difficile. The major MODIFY trial has proven the efficacy, pooled analysis of MODIFY 1 AND 2 trials demonstrated the following results as compared to placebo (bezlotoxumab: 129/781 [16.5] placebo:206/773 [26.6]-10.0% [95% CI-14.0 to-6.0], p<0.0001) with number needed to treat (NNT) of 10. All other observational studies also showed a positive response with bezlotoxumab in the prevention of C. difficile. In conclusion, bezlotoxumab is a great option adjunctive with standard of care CDI antibiotics for the prevention of rCDI in high-risk adults.

Research paper thumbnail of Silk fibroin: a promising bio-material for the treatment of heavy metal-contaminated water, adsorption isotherms, kinetics, and mechanism

Environmental Science and Pollution Research

Silk is the strongest natural biopolymer produced by silk worms possessing superior adsorbent pro... more Silk is the strongest natural biopolymer produced by silk worms possessing superior adsorbent properties and thus extensively used in various applications. The present study involved the preparation of powder form of a silk fibroin materials and their application in adsorption of heavy metals, particularly, iron from aqueous solution. The morphological and structural characteristic properties of this promising materials were examined by using different analytical techniques. Batch experiments were conducted within feasible parametric ranges to understand the effect of dose, time, concentration, pH, and reusability. Silk fibroin was effective for iron adsorption over a wide range of pH 6 to 10. The adsorption removal efficiency of 98% was attained for removal of iron from contaminated water at moderate dose of 0.25 g and contact time of 60 min, which is unprecedented by considering the environment benign nature of the material. The data was examined in different isotherm models wherein it fitted best in Langmuir adsorption model. Similarly, Langmuir isotherm model, with R2 value of 0.984 and KL 0.412 and maximum adsorption capacity as 12.82 mg g−1, suggests monolayer adsorption. Kinetic study with better R2 value of 0.941 represented the pseudo-second order kinetics governed by the chemisorption reaction. To understand the practical applicability of silk fibroin, the repeatability study up to 5 cycles were performed. The findings are very encouraging which confirmed the usage of silk fibroin as adsorbent for multiple cycles with marginal decrease in adsorption efficiency. Eventually, the material was tested for iron removal in real contaminated water which revealed its potential and selectivity for removal of iron in different matrix.

Research paper thumbnail of Non-Destructive testing to detect multiple cracks in reinforced concrete beam using electromechanical impedance technique

Materials Today: Proceedings

Research paper thumbnail of Nanofluids: A Review Preparation, Stability, Properties and Applications

International journal of engineering research and technology, 2016

Nanofluids, suspension of nano sized particles having higher conductivity than base fluid, has re... more Nanofluids, suspension of nano sized particles having higher conductivity than base fluid, has reported many interesting properties which gains the attention of researchers and proved vital in many applications. This document is a review article on nanofluids. The article provides the basic information about nanofluids, their preparation methods, stability analyses, thermophysical properties and applications. Also discusses the future scope of nanofluids. Keywords—nanofluids; nanofluids preparation; stability; thermophsical properties;

Research paper thumbnail of B.Sc. (Hons.) Nursing Entrance Examination - 2010

Research paper thumbnail of A Logic gate based Double Talk Detector for Acoustic Echo Cancellation

The occurrence of echo is one of the major problems faced by hands free telephone systems. Acoust... more The occurrence of echo is one of the major problems faced by hands free telephone systems. Acoustic echo cancellers (AEC) are used to improve the quality of speech by removing echo. Adaptive filters make it possible to cancel the echo after estimating it. Double talk occurs when both far and near speakers are activating simultaneously, results into the divergence of adaptive filter. Double talk detectors based on decision parameter calculation and comparing with threshold are used to freeze the filter adaptation during double talk periods. These detectors miss some double talks and increase the residual error. In this paper, we present a new way of detecting double talk using logic AND gate so that missed detection rate decreases and acoustic echo canceller performance improves.

Research paper thumbnail of Global Capitalism and Its Impact on Education in English Language

This article is going to examine the surfacing of a new stage of global capitalism, called inform... more This article is going to examine the surfacing of a new stage of global capitalism, called informationalism (a term coined by Castells), and its consequences f or English language teaching, with its focal point resting on three cru cial issues. First, how globalization has resulted in the further spread of English as an int ernational language and how there is a shift of authority from the native to the nonnative speak ers of the language. Second, how the economic and employment trends today are changing t he way English is used with special reference to nonnative speakers who need to use the English language daily for international collaborations and negotiations, presenting intrica te ideas, and critical explanation of rapidly changing information. Finally, how new info rmation technologies which are transforming the notions of literacy and are making on- line navigation and research, interpretation and understanding of hypermedia, and synchronous and asynchronous on-line communic...

Research paper thumbnail of A Study of Spirometric Lung Function Tets and Its Correlation with High Resolution Computed Tomography in Patients of Rheumatoid Arthritis

Journal of Evolution of medical and Dental Sciences, 2013

Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis of... more Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis often with non specific systemic symptoms. Pleuropulmonary involvement is a important cause of morbidity and mortality in patients of rheumatoid arthritis. The extra articular manifestations like bronchiectasis, interstitial lung disease, caplan syndrome are well known complications of rheumatoid arthritis 1 . To make these things more clear, the present study has was conducted enrolling 50 patients of rheumatoid arthritis coming to Medicine Department of Sri Guru

Research paper thumbnail of New Teaching Methodologies

Research paper thumbnail of Treatment methods for removal of pharmaceuticals and personal care products from domestic wastewater

Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology, 2019

Abstract Rapid urbanization and overuse of pharmaceuticals and personal care products has resulte... more Abstract Rapid urbanization and overuse of pharmaceuticals and personal care products has resulted in their occurrence in water bodies and wastewater streams worldwide. In the past few years, high concentrations of antibiotics, analgesics, antiepileptics, and antimicrobial agents have been detected in Indian rivers and domestic effluents as well. Despite trace concentrations, these micropollutants escape conventional treatment systems and find their way in effluents of sewage treatment plants. This is attributed to certain properties such as log Kow, water solubility, nonbiodegradability, etc. In order to address these shortcomings, functionalized adsorbents and various advanced treatment methods such as ozonation, membrane processes, and advanced photocatalytic materials have been developed. In this chapter a comparison of state of the art treatment methods has been done and their shortcomings have been discussed. Future research directions have also been suggested.

Research paper thumbnail of Enhancement of Immunity and Health in Neonates and Infants

Journal of Neonatology, 2021

Immunity is protective mechanism of the body against infection, diseases, and cancers. The strong... more Immunity is protective mechanism of the body against infection, diseases, and cancers. The stronger the immunity is the healthier we are. With increasing environmental change worldwide, increase of new emerging diseases and infection over last few decades, it has become imperative to move toward prevention more than the treatment. The immune mechanism in pediatric population especially neonates and infants is much different than adults and is yet evolving. The development of immunity starts in utero and is dependent on several factors. The various efforts to improve immunity and health should start from antenatal period focusing on overall health and nutrition of mother. Maternal nutrition, antenatal steroids, and delayed cord clamping are helpful in decreasing various neonatal morbidities which include respiratory distress syndrome, sepsis, necrotizing enterocolitis, intraventricular hemorrhage, and mortality. After birth during initial 6 months, exclusive breastfeeding, growth mon...

Research paper thumbnail of Enhanced photocatalytic degradation of antimicrobial triclosan using rGO–TiO2 composite under natural solar illumination

Journal of Materials Science: Materials in Electronics, 2020

In the present study, the enhancement in the photocatalytic degradation of triclosan after incorp... more In the present study, the enhancement in the photocatalytic degradation of triclosan after incorporation of reduced graphene oxide (rGO) in pristine TiO 2 is investigated. Triclosan is an antimicrobial compound found in commonly used personal care products. The study involved the synthesis of reduced graphene oxide-titania composite using the improved Hummer and hydrothermal methods. The optimum rGO content in the composite was found to be 10 wt% (RT10). The composite was characterized using X-ray diffraction (XRD), Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), UV-Vis spectroscopy, Scanning electron microscopy (SEM), and Brunauer-Emmett-Teller surface area (BETSA). The experimental conditions viz. catalyst dose, initial triclosan concentration, and solution pH were studied. The surface area of the composite was substantially higher than either of TiO 2 and GO. The photocatalytic reaction followed pseudo-first-order kinetics with the highest rate constant of 0.251 h −1 obtained for RT10. The scavenging experiment indicated the role of hydroxyl radical in the degradation mechanism. The composite displayed efficient degradation under natural sunlight attributed to narrowing of band gap. It also performed effectively in secondary effluent containing triclosan despite matrix effect. Thus, the composite has potential application as a promising photocatalyst in tertiary treatment of water and wastewater.

Research paper thumbnail of Neonatal COVID-19 Infection Management

Journal of Neonatology, 2020

Coronavirus disease 19 (COVID-19) infection pandemic has affected remarkable morbidity and mortal... more Coronavirus disease 19 (COVID-19) infection pandemic has affected remarkable morbidity and mortality in a very short span of time. The overall disease profile and epidemiology is yet evolving but it seems to be highly infectious. Perinatal coronavirus infection is altogether a different perspective which has to be taken care of in a different way.

Research paper thumbnail of Teratocarcinosarcoma of the Nasal and Maxillary Sinus Mass- a Rare Case

Journal of Evolution of Medical and Dental Sciences, 2019

A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on p... more A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on pain in the eyes and headache and progress to nasal mass within period of 3 months. Routine haematological and biochemical investigations were done, which were normal at the time of presentation. Nasal endoscopy was done which showed nasal mass which bleeds on touch. A computed tomography (CT) scan face and neck revealed an inhomogenously enhancing soft tissue density lesion measuring 5.7*3.3*3.9 cm involving left maxillary sinus extending to left ethmoid sinus, left nasal cavity reaching up to posterior choana abutting the nasal septum (Figure 1).

Research paper thumbnail of Incidental finding of pulmonary lymphangitis carcinomatosa in a patient of chest trauma

Indian Journal of Anaesthesia, 2019

70 Indian Journal of Anaesthesia | Volume 63 | Issue 1 | January 2019 This is an open access jour... more 70 Indian Journal of Anaesthesia | Volume 63 | Issue 1 | January 2019 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‐NonCommercial‐ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‐commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. How to cite this article: Singh S, Lalin D, Verma VK. Management of local anaesthetic systemic toxicity by timely lipid resuscitation in a paraturient ‐ A case report. Indian J Anaesth 2019;63:68‐70. © 2019 Indian Journal of Anaesthesia | Published by Wolters Kluwer ‐ Medknow Access this article online

Research paper thumbnail of Migration of Students- A Comparative Study among Different Countries of the World

International Journal of Trend in Scientific Research and Development, 2019

Going abroad has now become trend for the youngsters mainly in India. Students go abroad for thei... more Going abroad has now become trend for the youngsters mainly in India. Students go abroad for their higher education and majority of them stays there and don't come back. The reason for not coming back can be influenced by many factors like: the living standard in the foreign countries, the method of education, the earnings etc. This paper shows the statistical data of the students going abroad from India for higher education as well as the students coming to India for further education and its comparison with the past years. This paper will also examine the various factors which influence the students to go abroad for further education.

Research paper thumbnail of Biomimetic lipophilic activated carbon for enhanced removal of triclosan from water

Journal of Colloid and Interface Science, 2019