Hassan Kermanshahi - Academia.edu (original) (raw)

Papers by Hassan Kermanshahi

DOAJ (DOAJ: Directory of Open Access Journals), Aug 31, 2022

The effects of curcumin and its nano-micelle form on body weight, insulin resistance, adiponectin... more The effects of curcumin and its nano-micelle form on body weight, insulin resistance, adiponectin, and blood biochemical parameters of streptozotocin-induced diabetic rats were studied. Diabetes was induced in fifty male Wistar rats which were divided into five groups treated with 1) no dietary supplements, 2 and 3) 40 and 80 mg curcumin/kg of feed, and 4 and 5) 40 and 80 mg nano-micelle curcumin/kg of feed. A group of ten untreated male Wistar rats was also considered a healthy control group. The serum concentrations of AST, ALT, glucose, insulin, triglycerides, cholesterol, HDL-C, LDL-C, and adiponectin, as well as insulin resistance, were assessed. Body weight and weight of liver, heart, and pancreas were also evaluated. Induction of diabetes increased the serum concentrations of AST, ALT, glucose, triglycerides, cholesterol, LDL-C, and insulin resistance and decreased the serum levels of insulin, adiponectin, and HDL-C, as well as body weight and weight of the heart and pancreas (p < 0.05). Nano-micelle form of curcumin alleviated the negative effects of glucose, lipid profile, and liver enzymes in diabetic rats (p < 0.05). In conclusion, the nano-micelle form of curcumin showed better efficiency compared to curcumin for improving the adverse effects of diabetes. It can be suggested that the nano-micelle form of curcumin at specific doses might be useful for diabetes treatment.

DOAJ (DOAJ: Directory of Open Access Journals), Dec 1, 2021

DOAJ (DOAJ: Directory of Open Access Journals), Aug 1, 2022

This experiment was conducted to evaluate the effect of turmeric rhizome powder (TRP) on performa... more This experiment was conducted to evaluate the effect of turmeric rhizome powder (TRP) on performance, egg quality and some serum parameters of laying hens (240 Hy-Line hens, 100 wk old) in a completely randomized block design. Four groups of hens of 60 birds each, received five levels of TRP (0.0, 0.5, 1.0, 1.5, and 2.0 gll<gof diet) in wheatsoybean meal based diets for 4 weeks. The result showed that increasing levels of TRP decreased (P<0.05) feed conversion rate (FCR) during the last 3 weeks of experiment There was no significant effect (P>0.05) for different levels of TRP on specific gravity, egg shell thickness, egg shell weight and egg shell weight to egg weight ratio. The increasing levels ofTRP significantly (P<0.05) increased the yolk colour index. The hens fed with 0.0 level of TRP had higher (P><0.05) triglyceride (TG), Total cholesterol, and LDL-cholesterol in blood serum compared with the others, while the HDL-cholesterol was higher (P><0.05) for TRP levels of 1.0 and 1.5. Results of this experiment suggest that TRP in the diets of layers had no adverse effect on egg quality and performance and may have reduced cholesterol and triglyceride in blood serum.

Iranian Journal of Applied Animal Science, Mar 1, 2015

This study was conducted to determine the effects of supplemented curcumin (CMN), derived from pl... more This study was conducted to determine the effects of supplemented curcumin (CMN), derived from plant Curcuma longa, extract on performance and blood parameters of acetaminophen (ACT) induced quail hepatic injury. 240 quails from 0-37 days of age were used in a completely randomized design with 4 treatments of 4 replicates each and 15 chickens per replicate. All groups received 750 mg/kg body weight oral doses of ACT at 12 days of age. Japanese quails were divided into four groups: control (no CMN), commercial diet with 20 g CMN per ton, commercial diet with 40 g CMN per ton and commercial diet with 60 g CMN per ton. Feed intake and body weight gain were recorded weekly. Blood albumin, glucose, total protein, triglyceride, aspartate aminotransferase, alanine aminotransferase, bilirubin, uric acid and creatinine were determined at 28 and 35 days of age. Adding curcumin to the diets significantly increased serum aspartate aminotransferase at 28 days of age (P<0.05) and decreased triglyceride and bilirubin at 35 days of age (P<0.05). There were no significant differences in performance and other blood parameters among the treatment groups at 28 and 35 days of age. The data indicated that curcumin is a natural antioxidant hepatoprotective agent against hepatotoxicity induced by acetaminophen model. Thus, curcumin may have a therapeutic value in drug-induced hepatotoxicity as well as in acetaminophen therapy.

Journal of Animal and Veterinary Advances, Dec 1, 2010

Global Veterinaria, Nov 12, 2010

European Poultry Science (EPS)

Pizhūhishhā-yi ̒ulum-i dāmī-i Īrān, 2015

An experiment was conducted to investigate the effects of fruit hydroalcoholic extract of Withani... more An experiment was conducted to investigate the effects of fruit hydroalcoholic extract of Withania coagulans (WC) and 1, 25-dihydroxycholecalciferol on bone mechanical and histological properties of male chickens. Diets were arranged factorially (2×3×2) consisted of a positive control with adequate Ca (10.4 g/kg diet) and nonphytate P (NPP; 5 g/kg diet) exceed the requirements suggested in the Ross 308 broiler nutrient specifications and a negative control diet with Ca (7.3 g/kg diet) and nonphytate P (NPP; 5 g/kg diet), three levels of Withania coagulans (0, 100 and 200 mg/kg diet), and two levels of 1, 25-dihydroxycholecalciferol (0 and 0.5 μg/kg diet). Both Ca and P retention significantly increased by reducing dietary Ca level (P

Poultry Science, 2021

Clostridium perfringens-induced necrotic enteritis (NE) is an economically important disease of b... more Clostridium perfringens-induced necrotic enteritis (NE) is an economically important disease of broiler chickens. The present study evaluated the effect of C. perfringens on the intestinal histomorphometry, enteric microbial colonization, and host immune responses using 3 experimental NE reproduction methods. The experimental groups consisted of 1) unchallenged Control diet (corn-soybean meal), 2) Control diet + Eimera inoculation at d 11 followed by C. perfringens challenge at d 15 (ECp), 3) Wheat-based diet + C. perfringens challenge (WCp), and 4) Wheat-based diet + Eimeria inoculation followed by C. perfringens challenge (WECp). The results showed that chickens receiving ECp and WECp had reduced (P < 0.05) bird performance coupled with enteric gross lesions and epithelial damage at d 17 and 24 of age compared to unchallenged control birds. These ECp and WECp administered birds also had increased (P < 0.05) ileal colonization by clostridia and E. coli at d 17 and 24, while the resident Lactobacillus counts were reduced (P < 0.05) at d 24 of age. Furthermore, at d 24, jejunal transcription of IL-6, IL-10, annexin-A1 and IL-2 genes was upregulated (P < 0.05) in the ECp group, whereas the transcription of TNF receptor associated factor (TRAF)-3 gene was increased (P < 0.05) in WECp treated birds when compared to unchallenged control group. Additionally, stimulation of chicken splenocytes and cecal tonsilocytes with virulent C. perfringens bacilli or their secretory proteins resulted in a higher (P < 0.05) frequency of T cells and their upregulation of MHC-II molecule, as determined by flow cytometry. These findings suggest that C. perfringens, while inducing epithelial damage and changes in microbiota, can also trigger host immune responses. Furthermore, NE reproduction methods using coccidia with or without the wheat-based dietary predisposition seem to facilitate an optimal NE reproduction in broiler chickens and thus, may provide better avenues for future C. perfringens research.

This study was carried out to investigate the effects of different levels of cinnamon powder (CNP... more This study was carried out to investigate the effects of different levels of cinnamon powder (CNP), with antibiotic (Virginiamycin) and probiotic (Primalac) on performance and carcass characteristics in broiler chicks for 42 days using a completely randomized design. A total of 384 day-old male broiler chicks (Ross 308) were randomly assigned to 8 treatments , 4 replicates and 12 chicks per replicate. The experimental treatments consisted of: Basal diet (BD), BD + 0.1% CNP, BD + 0.2% CNP, BD + 0.3% CNP, BD + Primalac, BD + 0.2% CNP + Primalac, BD + Virginiamycin and BD + 0.2% CNP + Virginiamycin. In starter period there were significant differences among treatments for feed intake. No significant differences were observed in among groups other performance parameters. Adding 0.1% and 0.3% CNP in treatments 2 and 3 (T2,T3) significantly decreased abdominal fat pad weight at 42d of age. This study showed that inclusion of CNP in broiler diets had not remarkable effects on performance, but adding 0.1% and 0.3% CNP significantly decreased abdominal fat pad of broiler chicks.

Aim EAAP aims to bring to our annual meetings, speakers who can present the latest findings and v... more Aim EAAP aims to bring to our annual meetings, speakers who can present the latest findings and views on developments in the various fields of science relevant to animal production and its allied industries. In order to sustain the quality of the scientific program that will continue to entice the broad interest in EAAP meetings we have created the "EAAP Program Foundation". This Foundation aims to support: • Invited speakers by funding part or all of registration and travel costs. • Delegates from less favoured areas by offering scholarships to attend EAAP meetings. • Young scientists by providing prizes for best presentations. The "EAAP Program Foundation" is an initiative of the Scientific Committee (SC) of EAAP. The Foundation is aimed at stimulating the quality of the scientific program of the EAAP meetings and to ensure that the science meets societal needs. In its first year (2003), the "EAAP Program Foundation" concentrated on the program of the Genetics commission. For the coming years the activities will be broadened to the entire meeting. The Foundation Board of Trustees oversees theses aims and seeks to recruit sponsors to support its activities. Sponsorships We distinguish three categories of sponsorship: Student award sponsor, Gold sponsor, and Sponsor. The sponsors will be acknowledged during the scientific sessions. The names of the Student Award sponsors will be linked to the awards given to young scientists with the best presentation. Gold Sponsors and Student Award sponsors will have the opportunity to advertise their activities during the meeting and their support for EAAP.

Introduction Poultry meat enriched with long-chain polyunsaturated fatty acids n-3 (PUFA Lc n-3) ... more Introduction Poultry meat enriched with long-chain polyunsaturated fatty acids n-3 (PUFA Lc n-3) can make a nutritionally meaningful contribution to Western diets in which consumption of PUFA Lc n-3 is low. Enrichment of poultry meat with this fatty acid is usually achieved by inclusion of fish oil in broiler diet (23, 24). However, meat enriched in this way is susceptible to quality deterioration by lipid oxidation during storage or cooking, leading to reduction in nutritive value and accumulation of lipid oxidation products (10). Oxidation is a very general process affecting lipids, pigments, proteins, DNA, carbohydrates, and vitamins (11). The objective of this study was to evaluate the effects of dietary α-tocopherol (α-Toc), pomegranate peel extract (PPE) and pomegranate peel (PP) on fatty acid profile, aoxidation and phenolic compounds in raw thigh and breast meat during refrigeration. Materials and methods Peels of pomegranate were harvested in October 2011 from pomegranate trees (Ardestani, variety) in Khorasan Razavi province (East, Iran). Dried powders of peels (2.5 g) were extracted with 40 mL of methanol solvent at room temperature for 6 hours. Three hundred and eighty four 1-d-old male broiler chicks (Ross 308) were randomly allotted to 8 groups with 4 replicates of 12 birds. Eight dietary treatments including control diet without feed additives, control diet mixed with 200 mg/kg α-Toc, control diet mixed with PPE (100, 200 and 300 mg/kg), and control diet mixed with PP (1, 2 and 3 g/kg). In all diets 2% fish oil were added to enhance the enrichment of unsaturated n-3 fatty acid in birds. One broiler chick was randomly selected from each pen of 42 d of age. The antioxidative potential and various meat quality characteristics were determined on 0, 7, and 11 days of refrigerated storage. Total phenols content in the aqueous supernatant was estimated by the Folin-Ciocalteu method (33). 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity was estimated according to Blois' (2). Lipid oxidatio [...]

A 42-day feeding trial was conducted to determine the effect of cLF36 on the performance and inte... more A 42-day feeding trial was conducted to determine the effect of cLF36 on the performance and intestinal histological features of broilers. One hundred eighty day-old ROSS308 broilers were distributed to 3 treatments following a completely randomized design: basal diet without cLf, diet with 20 cLF mg / kg feeds and diet with 300 mg antibiotics / kg feed offered during the starter and grower stages. Performance parameters and intestinal villi height and crypt depth were determined. Chickens fed with antibiotics had a higher daily gain and higher feed intake () than the control and peptide groups, while at the end of the experiment (42 days), significant differences between all treatments. Peptide-supplemented treatment had no significant effect on functional parameters in comparison with control treatment in any of the breeding courses. The results of this experiment showed that although the peptide could not have a significant effect on intestinal morphology in different parts of the intestine, it increased the morphology of the intestine in comparison with the control treatment. Also, the effects of peptide on growth performance and intestinal morphology are comparable to the results of antibiotic treatment, although further studies in the field and laboratory are needed to allow this peptide to be introduced as an alternative to antibiotics for the treatment of necrotic enteritis.

British Poultry Science, 2019

Smet (2019): Effects of methionine and guanidinoacetic acid supplementation on performance and en... more Smet (2019): Effects of methionine and guanidinoacetic acid supplementation on performance and energy metabolites in breast muscle of male broiler chickens fed corn-soybean diets, British Poultry Science,

Journal of Animal Physiology and Animal Nutrition, 2015

SummaryIn recent few years, there have been some attempts to find a reliable indicator trait as a... more SummaryIn recent few years, there have been some attempts to find a reliable indicator trait as a selection criterion against susceptibility to ascites syndrome (AS). Blood parameters were of great interest as they could be measured in live animals without implementing an ascites‐inducing challenge (AIC). In this work, the suitability of some blood parameters was evaluated for diagnosing AS‐susceptible chicks in later steps of the disease in trial 1 as well as their early predictive ability in trial 2. In the first trial, one hundred 1‐day‐old chicks from two pure broiler lines namely S1 and S2 and, in the second trial, 226 1‐day‐old chicks from line S2 were subjected to AIC. Saline drinking water (1200 mg/l) and lower‐than‐standard ambient temperatures were the implemented AICs in trials 1 and 2 respectively. The blood parameters including pH, partial pressure of O2 (pO2), partial pressure of CO2 (pCO2), bicarbonate ion concentration (BIC), percentage of haematocrit (HCT) and satur...

Iranian Journal of Applied Animal Science, 2015