Ec Henley - Academia.edu (original) (raw)
Papers by Ec Henley
Soy foods have low glycemic and insulin response indices in normal weight subjects
The FASEB Journal, 2007
Joan Fischer for sharing their invaluable expertise as they served on my thesis committee. Drs. A... more Joan Fischer for sharing their invaluable expertise as they served on my thesis committee. Drs. Aaron Tabor and Robert Blair, of Physicians Pharmaceuticals, Inc., for the generous provision of the soy and casein shakes, and for input regarding the study design. Dr. Clifton Baile for assistance with obtaining funding for this project. Dr. Daniel Hall for statistical analyses and advice. Dr. Emma Laing for brilliant editorial and proofreading assistance. Ruth Gildea for capable coordination of the FOCUS study. Norman Pollock for priceless technical (and, at times, emotional!) support. Student workers, Jennifer Teems, Sara Serji, Savanna Martin, and Allison Gaines for many hours of hard work and help with testing and data entry-we could not have done this without you! Special thanks go to my parents, James and Mary Lynne Principe, for their unwavering support, love and encouragement. I know that you both will always be behind me in any endeavor one-hundred and ten percent, and this gives me more security than words can express-THANK YOU. My brothers, Ryan and Jeremy, for your huge hugs, sincere love and happiness for me in my successes and for bringing me so much joy and laughter as your "big sister." The Tang family, for the endless supply of sweet treats, encouraging cards, herbal remedies, and for being my "family away from home." My best friends and former "roomies," Joanna, Nikki, Meghan, and Jenique! for putting up with my exceptionally loud alarm clocks and v freezer-stuffing supply of frozen dinners. I am so grateful for your patience and unconditional love! My other best friends, Elizabeth, Kalere, and Sam for countless refreshing conversations for making time for me despite my limited social calendar. Sam, I will never forget the quality time we spent completing rather unexciting research tasks-you are truly a first-rate friend! I appreciate all of you very much, and I am so grateful to be a part of your lives. vi
Nutrition journal, Jan 27, 2006
Foods with a low glycemic index (GI) may provide a variety of health benefits. The objective of t... more Foods with a low glycemic index (GI) may provide a variety of health benefits. The objective of the present study was to measure the GI and insulin index (II) of select soy foods. The study was conducted in two parts with low-carbohydrate products being tested separately. In Experiment 1, subjects averaged 23.2 years of age with BMI = 22.0 kg/m2, while subjects in Experiment 2 averaged 23.9 years of age with BMI = 21.6 kg/m2. The reference (glucose) and test foods were served in portions containing 10 g of carbohydrates in Experiment 1 (two test foods) and 25 g of carbohydrates in Experiment 2 (four test foods). Subjects consumed the reference food twice and each test food once. For each test, subjects were instructed to consume a fixed portion of the reference food or test food together with 250 g of water within 12 min. Blood samples were collected before each test and at 15, 30, 45, 60, 90, and 120 min after consumption of reference or test foods to quantify glucose and insulin. ...
Science, 1977
Collimated beams of 3.75 million electron volt protons were used to examine a 2-millimeter length... more Collimated beams of 3.75 million electron volt protons were used to examine a 2-millimeter length of the root end of human hair; the concentrations of some hair root elements were correlated with the results of standard clinical assays of blood samples. The technique should be useful for the analysis of micro amounts of biological tissue.
Nutrition Research, 2014
Human clinical trials targeted at preventing gains in body weight using soy protein and isoflavon... more Human clinical trials targeted at preventing gains in body weight using soy protein and isoflavones are limited to adults and yield conflicting results. We hypothesized that daily intake of soy protein/isoflavones would attenuate gains in body weight to a greater extent than a casein-based control in 18 to 19 year-old females. To test this hypothesis, we conducted a randomized, double blind, placebo-controlled trial over 16 weeks to examine the effects of a soy protein/isoflavone-based meal replacement (experimental group) versus a casein-based meal replacement (control group) on body weight and body composition variables in female college freshmen (N = 120). Fat mass (FM), fat-free soft tissue mass (FFST), and percent body fat (%BF) were measured using dual energy X-ray absorptiometry (DXA; Delphi A). Repeated measures mixed models were used to determine the effects of treatment on anthropometric and body composition variables (body weight, waist circumference, FM, FFST, and %BF). No significant group × time interactions were observed, even when body mass index was controlled for in the analysis. Over 16 weeks, body weight, FM, FFST, and %BF significantly increased in both groups (P < .05). Our findings show that female college freshmen gained a significant amount of weight over the course of the 16-week study. Gains in body weight and FM were similar among participants assigned to the soy protein/isoflavone-and the casein-based meal replacements. Future research is warranted to determine the effects of soy protein/isoflavone-and casein-based meal replacements versus a non-intervention (i.e., non-protein based) control.
Advances in food and nutrition research, 2010
Child malnutrition is increasing in Africa. Protein deficiency is an important cause since protei... more Child malnutrition is increasing in Africa. Protein deficiency is an important cause since protein is essential for both growth and maintenance of muscle mass. Sorghum is a major staple food in Africa on account of its hardiness as a crop. However, sorghum protein is very deficient in the indispensable amino acid lysine and on cooking has poor protein digestibility. This results in sorghum having a very low Protein Digestibility Corrected Amino Acid Score (PDCAAS). The Africa Biofortified Sorghum project, a Grand Challenges in Global Heath project, is undertaking research to biofortify sorghum in terms of protein and micronutrient quality using genetic engineering. Lysine and protein digestibility have been improved by suppression of synthesis of the kafirin storage proteins. Transgenic biofortified sorghum has double the PDCAAS of conventional sorghum. This improvement should enable a young child to meet most of its protein and energy requirements from biofortified sorghum porridge...
Soy foods have low glycemic and insulin response indices in normal weight subjects
The FASEB Journal, 2007
Joan Fischer for sharing their invaluable expertise as they served on my thesis committee. Drs. A... more Joan Fischer for sharing their invaluable expertise as they served on my thesis committee. Drs. Aaron Tabor and Robert Blair, of Physicians Pharmaceuticals, Inc., for the generous provision of the soy and casein shakes, and for input regarding the study design. Dr. Clifton Baile for assistance with obtaining funding for this project. Dr. Daniel Hall for statistical analyses and advice. Dr. Emma Laing for brilliant editorial and proofreading assistance. Ruth Gildea for capable coordination of the FOCUS study. Norman Pollock for priceless technical (and, at times, emotional!) support. Student workers, Jennifer Teems, Sara Serji, Savanna Martin, and Allison Gaines for many hours of hard work and help with testing and data entry-we could not have done this without you! Special thanks go to my parents, James and Mary Lynne Principe, for their unwavering support, love and encouragement. I know that you both will always be behind me in any endeavor one-hundred and ten percent, and this gives me more security than words can express-THANK YOU. My brothers, Ryan and Jeremy, for your huge hugs, sincere love and happiness for me in my successes and for bringing me so much joy and laughter as your "big sister." The Tang family, for the endless supply of sweet treats, encouraging cards, herbal remedies, and for being my "family away from home." My best friends and former "roomies," Joanna, Nikki, Meghan, and Jenique! for putting up with my exceptionally loud alarm clocks and v freezer-stuffing supply of frozen dinners. I am so grateful for your patience and unconditional love! My other best friends, Elizabeth, Kalere, and Sam for countless refreshing conversations for making time for me despite my limited social calendar. Sam, I will never forget the quality time we spent completing rather unexciting research tasks-you are truly a first-rate friend! I appreciate all of you very much, and I am so grateful to be a part of your lives. vi
Nutrition journal, Jan 27, 2006
Foods with a low glycemic index (GI) may provide a variety of health benefits. The objective of t... more Foods with a low glycemic index (GI) may provide a variety of health benefits. The objective of the present study was to measure the GI and insulin index (II) of select soy foods. The study was conducted in two parts with low-carbohydrate products being tested separately. In Experiment 1, subjects averaged 23.2 years of age with BMI = 22.0 kg/m2, while subjects in Experiment 2 averaged 23.9 years of age with BMI = 21.6 kg/m2. The reference (glucose) and test foods were served in portions containing 10 g of carbohydrates in Experiment 1 (two test foods) and 25 g of carbohydrates in Experiment 2 (four test foods). Subjects consumed the reference food twice and each test food once. For each test, subjects were instructed to consume a fixed portion of the reference food or test food together with 250 g of water within 12 min. Blood samples were collected before each test and at 15, 30, 45, 60, 90, and 120 min after consumption of reference or test foods to quantify glucose and insulin. ...
Science, 1977
Collimated beams of 3.75 million electron volt protons were used to examine a 2-millimeter length... more Collimated beams of 3.75 million electron volt protons were used to examine a 2-millimeter length of the root end of human hair; the concentrations of some hair root elements were correlated with the results of standard clinical assays of blood samples. The technique should be useful for the analysis of micro amounts of biological tissue.
Nutrition Research, 2014
Human clinical trials targeted at preventing gains in body weight using soy protein and isoflavon... more Human clinical trials targeted at preventing gains in body weight using soy protein and isoflavones are limited to adults and yield conflicting results. We hypothesized that daily intake of soy protein/isoflavones would attenuate gains in body weight to a greater extent than a casein-based control in 18 to 19 year-old females. To test this hypothesis, we conducted a randomized, double blind, placebo-controlled trial over 16 weeks to examine the effects of a soy protein/isoflavone-based meal replacement (experimental group) versus a casein-based meal replacement (control group) on body weight and body composition variables in female college freshmen (N = 120). Fat mass (FM), fat-free soft tissue mass (FFST), and percent body fat (%BF) were measured using dual energy X-ray absorptiometry (DXA; Delphi A). Repeated measures mixed models were used to determine the effects of treatment on anthropometric and body composition variables (body weight, waist circumference, FM, FFST, and %BF). No significant group × time interactions were observed, even when body mass index was controlled for in the analysis. Over 16 weeks, body weight, FM, FFST, and %BF significantly increased in both groups (P < .05). Our findings show that female college freshmen gained a significant amount of weight over the course of the 16-week study. Gains in body weight and FM were similar among participants assigned to the soy protein/isoflavone-and the casein-based meal replacements. Future research is warranted to determine the effects of soy protein/isoflavone-and casein-based meal replacements versus a non-intervention (i.e., non-protein based) control.
Advances in food and nutrition research, 2010
Child malnutrition is increasing in Africa. Protein deficiency is an important cause since protei... more Child malnutrition is increasing in Africa. Protein deficiency is an important cause since protein is essential for both growth and maintenance of muscle mass. Sorghum is a major staple food in Africa on account of its hardiness as a crop. However, sorghum protein is very deficient in the indispensable amino acid lysine and on cooking has poor protein digestibility. This results in sorghum having a very low Protein Digestibility Corrected Amino Acid Score (PDCAAS). The Africa Biofortified Sorghum project, a Grand Challenges in Global Heath project, is undertaking research to biofortify sorghum in terms of protein and micronutrient quality using genetic engineering. Lysine and protein digestibility have been improved by suppression of synthesis of the kafirin storage proteins. Transgenic biofortified sorghum has double the PDCAAS of conventional sorghum. This improvement should enable a young child to meet most of its protein and energy requirements from biofortified sorghum porridge...