Claudio Henriques - Academia.edu (original) (raw)

Papers by Claudio Henriques

3 Juliane Fonseca de Oliveira, Julia Moreira Pescarini, Moreno de Souza Rodrigues, Bethania 4 de ... more 3 Juliane Fonseca de Oliveira, Julia Moreira Pescarini, Moreno de Souza Rodrigues, Bethania 4 de Araujo Almeida, Claudio Maierovitch Pessanha Henriques, Fabio Castro Gouveia, Elaine 5 Teixeira Rabello, Gustavo Correa Matta, Mauricio L. Barreto, Ricardo Barros Sampaio 6 7 1 Centro de Integração de Dados e Conhecimentos para Saúde, Fiocruz, Salvador, Bahia, Brazil 8 2 Laboratório de Análise e Visualização de dados, Fiocruz, Rondônia, Brazil 9 3 Gerência Regional de Brasília, Fiocruz, Brasília, Brazil 10 4 Casa Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil 11 5 Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil 12 6 Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil 13 7 Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Bahia, Brazil 14 15 *Corresponding author: 16 Ricardo Barros Sampaio e-mail: rsampaio.br@gmail.com 17 18 All authors have contributed equaly to this work 19 20

Revista Brasileira de Epidemiologia, 2021

Strengthening the surveillance and information activities is urgent and essential to reduce the t... more Strengthening the surveillance and information activities is urgent and essential to reduce the transmission force of SARS-CoV-2*

Comunicação em Ciências da Saúde, 2020

Objetivo: Avaliar acurácia de testes sorológicos para diagnóstico de Zika. Método: Utilizadas as... more Objetivo: Avaliar acurácia de testes sorológicos para diagnóstico de Zika. Método: Utilizadas as bases: Embase, Cochrane, Pubmed e Portal de Evidências da BVS. Critérios de inclusão consideraram intervenção, indicação e desenho do estudo. Na avaliação de qualidade de evidências aplicou-se a classificação de QUADAS II. Resultados: Selecionados 3 artigos que referem à avaliação e acurácia de testes IgM e IgG, comparado com o método de biologia molecular RT- PCR e o PRNT como padrão ouro. Conclusão: Dadas as características e velocidade de propagação da doença, testes diagnósticos acessíveis, precisos e de baixo custo são ferramentas essenciais para o trabalho de atenção e vigilância.

Background: Science studies have been a field of research for different knowledge areas and they ... more Background: Science studies have been a field of research for different knowledge areas and they have been successfully used to analyse the construction of scientific knowledge, practice and dissemination. In this study, we aimed to verify how the Zika epidemic has moulded scientific production worldwide analysing international collaboration and the knowledge landscape through time, research topics and country involvement. Methodology: We searched the Web of Science (WoS) for studies published up to 31st December 2018 on Zika using the search terms zika, zkv or zikv. We analysed the scientific production regarding which countries have published the most, on which topics, as well as country level collaboration. We performed a scientometric analysis of research on Zika focusing on knowledge mapping and the scientific research path over time and space. Findings: We found two well defined research areas divided into three subtopics accounting for six clusters. With regard to country ana...

The Lancet. Infectious diseases, Jan 11, 2017

A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase... more A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase in congenital microcephaly cases, triggering a declaration of an international public health emergency. This is the final report of the first case-control study evaluating the potential causes of microcephaly: congenital Zika virus infection, vaccines, and larvicides. The published preliminary report suggested a strong association between microcephaly and congenital Zika virus infection. We did a case-control study in eight public maternity hospitals in Recife, Brazil. Cases were neonates born with microcephaly, defined as a head circumference of 2 SD below the mean. Two controls without microcephaly were matched to each case by expected date of delivery and area of residence. We tested the serum of cases and controls and the CSF of cases for detection of Zika virus genomes with quantitative RT-PCR and for detection of IgM antibodies with capture-IgM ELISA. We also tested maternal serum...

The New England journal of medicine, Apr 20, 2017

The first cases of a new illness involving fever and rash that was deemed to have been caused by ... more The first cases of a new illness involving fever and rash that was deemed to have been caused by Zika virus (ZIKV) infection in Brazil were reported in 2014, and the presence of the virus was confirmed in April 2015. In October 2015, an unusual increase in the number of cases of microcephaly among newborn infants was reported in Brazil; this disorder was apparently linked to ZIKV infection. From the first investigations of microcephaly, and from subsequent studies in Brazil and elsewhere, it is now clear that ZIKV is a cause of a range of neurologic disorders, including the Guillain-Barré syndrome (GBS) in adults and abnormalities in fetuses and newborn infants, including microcephaly.1 Here, we use routinely collected surveillance data and medical records to show how the spread of ZIKV in Brazil was associated with an increase in the incidence of GBS and microcephaly during 2015 and 2016. We also highlight the limitations of routinely collected data, which cannot yet explain, for example, why there were many fewer cases of microcephaly than expected in 2016. To explore the temporal and geographic distribution of ZIKV infection, we used data provided by municipalities and states in each of the five regions of Brazil, as compiled by the Ministry of Health. These data describe the number of suspected and confirmed cases of ZIKV infection and of cases reported as GBS and microcephaly (Sections 1 and 2 in the Supplementary Appendix, available with the full text of this letter at NEJM.org).

PloS one, 2017

The increased availability of influenza surveillance data in recent years justifies an actual and... more The increased availability of influenza surveillance data in recent years justifies an actual and more complete overview of influenza epidemiology in Latin America. We compared the influenza surveillance systems and assessed the epidemiology of influenza A and B, including the spatio-temporal patterns of influenza epidemics, in ten countries and sub-national regions in Latin America. We aggregated the data by year and country and characteristics of eighty-two years were analysed. We calculated the median proportion of laboratory-confirmed influenza cases caused by each virus strain, and compared the timing and amplitude of the primary and secondary peaks between countries. 37,087 influenza cases were reported during 2004-2012. Influenza A and B accounted for a median of 79% and, respectively, 21% of cases in a year. The percentage of influenza A cases that were subtyped was 82.5%; for influenza B, 15.6% of cases were characterized. Influenza A and B were dominant in seventy-five (91...

Zika virus (ZIKV) transmission in the Americas was first confirmed in May 2015 in Northeast Brazi... more Zika virus (ZIKV) transmission in the Americas was first confirmed in May 2015 in Northeast Brazil1. Brazil has the highest number of reported ZIKV cases worldwide…

Epidemiologia e Serviços de Saúde, 2016

Objective: to describe the first cases of microcephaly possibly related to Zika virus in live bor... more Objective: to describe the first cases of microcephaly possibly related to Zika virus in live born babies reported in the Metropolitan Region of Recife, Pernambuco State, Brazil. Methods: this was a descriptive case series study (cases reported between August 1 st and October 31 st 2015), using medical record data and data from a questionnaire answered by the mothers of the babies. Results: 40 microcephaly cases were confirmed, distributed in eight municipalities within the Metropolitan Region, with Recife itself having the highest concentration of cases (n=12); median head circumference was 29 cm, median chest girth was 31 cm and median weight was 2,628 grams; 21/25 cases had brain calcification, ventriculomegaly or lissencephaly; 27 of the 40 mothers reported rash during pregnancy, 20 in the first trimester and 7 in the second trimester, as well as itching, headache, myalgia and absence of fever. Conclusion: the majority of the cases bore the characteristics of congenital infection; the clinical condition of the majority of mothers suggested Zika virus infection during pregnancy.

The Lancet Infectious Diseases, 2016

Background The microcephaly epidemic, which started in Brazil in 2015, was declared a Public Heal... more Background The microcephaly epidemic, which started in Brazil in 2015, was declared a Public Health Emergency of International Concern by WHO in 2016. We report the preliminary results of a case-control study investigating the association between microcephaly and Zika virus infection during pregnancy. Methods We did this case-control study in eight public hospitals in Recife, Brazil. Cases were neonates with microcephaly. Two controls (neonates without microcephaly), matched by expected date of delivery and area of residence, were selected for each case. Serum samples of cases and controls and cerebrospinal fl uid samples of cases were tested for Zika virus-specifi c IgM and by quantitative RT-PCR. Laboratory-confi rmed Zika virus infection during pregnancy was defi ned as detection of Zika virus-specifi c IgM or a positive RT-PCR result in neonates. Maternal serum samples were tested by plaque reduction neutralisation assay for Zika virus and dengue virus. We estimated crude odds ratios (ORs) and 95% CIs using a median unbiased estimator for binary data in an unconditional logistic regression model. We estimated ORs separately for cases with and without radiological evidence of brain abnormalities. Findings Between Jan 15, 2016, and May 2, 2016, we prospectively recruited 32 cases and 62 controls. 24 (80%) of 30 mothers of cases had Zika virus infection compared with 39 (64%) of 61 mothers of controls (p=0•12). 13 (41%) of 32 cases and none of 62 controls had laboratory-confi rmed Zika virus infection; crude overall OR 55•5 (95% CI 8•6-∞); OR 113•3 (95% CI 14•5-∞) for seven cases with brain abnormalities; and OR 24•7 (95% CI 2•9-∞) for four cases without brain abnormalities. Interpretation Our data suggest that the microcephaly epidemic is a result of congenital Zika virus infection. We await further data from this ongoing study to assess other potential risk factors and to confi rm the strength of association in a larger sample size.

Lancet (London, England), Jan 29, 2016

In November, 2015, an epidemic of microcephaly was reported in Brazil, which was later attributed... more In November, 2015, an epidemic of microcephaly was reported in Brazil, which was later attributed to congenital Zika virus infection. 7830 suspected cases had been reported to the Brazilian Ministry of Health by June 4, 2016, but little is known about their characteristics. We aimed to describe these newborn babies in terms of clinical findings, anthropometry, and survival. We reviewed all 1501 liveborn infants for whom investigation by medical teams at State level had been completed as of Feb 27, 2016, and classified suspected cases into five categories based on neuroimaging and laboratory results for Zika virus and other relevant infections. Definite cases had laboratory evidence of Zika virus infection; highly probable cases presented specific neuroimaging findings, and negative laboratory results for other congenital infections; moderately probable cases had specific imaging findings but other infections could not be ruled out; somewhat probable cases had imaging findings, but t...

Rev Bras Cir Plast, Dec 1, 2009

Epidemiologia e Serviços de Saúde, 2016

MMWR. Morbidity and mortality weekly report, Jan 11, 2016

Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since lat... more Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraíba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of microcephaly. Pregnant women...

3 Juliane Fonseca de Oliveira, Julia Moreira Pescarini, Moreno de Souza Rodrigues, Bethania 4 de ... more 3 Juliane Fonseca de Oliveira, Julia Moreira Pescarini, Moreno de Souza Rodrigues, Bethania 4 de Araujo Almeida, Claudio Maierovitch Pessanha Henriques, Fabio Castro Gouveia, Elaine 5 Teixeira Rabello, Gustavo Correa Matta, Mauricio L. Barreto, Ricardo Barros Sampaio 6 7 1 Centro de Integração de Dados e Conhecimentos para Saúde, Fiocruz, Salvador, Bahia, Brazil 8 2 Laboratório de Análise e Visualização de dados, Fiocruz, Rondônia, Brazil 9 3 Gerência Regional de Brasília, Fiocruz, Brasília, Brazil 10 4 Casa Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil 11 5 Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil 12 6 Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil 13 7 Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Bahia, Brazil 14 15 *Corresponding author: 16 Ricardo Barros Sampaio e-mail: rsampaio.br@gmail.com 17 18 All authors have contributed equaly to this work 19 20

Revista Brasileira de Epidemiologia, 2021

Strengthening the surveillance and information activities is urgent and essential to reduce the t... more Strengthening the surveillance and information activities is urgent and essential to reduce the transmission force of SARS-CoV-2*

Comunicação em Ciências da Saúde, 2020

Objetivo: Avaliar acurácia de testes sorológicos para diagnóstico de Zika. Método: Utilizadas as... more Objetivo: Avaliar acurácia de testes sorológicos para diagnóstico de Zika. Método: Utilizadas as bases: Embase, Cochrane, Pubmed e Portal de Evidências da BVS. Critérios de inclusão consideraram intervenção, indicação e desenho do estudo. Na avaliação de qualidade de evidências aplicou-se a classificação de QUADAS II. Resultados: Selecionados 3 artigos que referem à avaliação e acurácia de testes IgM e IgG, comparado com o método de biologia molecular RT- PCR e o PRNT como padrão ouro. Conclusão: Dadas as características e velocidade de propagação da doença, testes diagnósticos acessíveis, precisos e de baixo custo são ferramentas essenciais para o trabalho de atenção e vigilância.

Background: Science studies have been a field of research for different knowledge areas and they ... more Background: Science studies have been a field of research for different knowledge areas and they have been successfully used to analyse the construction of scientific knowledge, practice and dissemination. In this study, we aimed to verify how the Zika epidemic has moulded scientific production worldwide analysing international collaboration and the knowledge landscape through time, research topics and country involvement. Methodology: We searched the Web of Science (WoS) for studies published up to 31st December 2018 on Zika using the search terms zika, zkv or zikv. We analysed the scientific production regarding which countries have published the most, on which topics, as well as country level collaboration. We performed a scientometric analysis of research on Zika focusing on knowledge mapping and the scientific research path over time and space. Findings: We found two well defined research areas divided into three subtopics accounting for six clusters. With regard to country ana...

The Lancet. Infectious diseases, Jan 11, 2017

A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase... more A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase in congenital microcephaly cases, triggering a declaration of an international public health emergency. This is the final report of the first case-control study evaluating the potential causes of microcephaly: congenital Zika virus infection, vaccines, and larvicides. The published preliminary report suggested a strong association between microcephaly and congenital Zika virus infection. We did a case-control study in eight public maternity hospitals in Recife, Brazil. Cases were neonates born with microcephaly, defined as a head circumference of 2 SD below the mean. Two controls without microcephaly were matched to each case by expected date of delivery and area of residence. We tested the serum of cases and controls and the CSF of cases for detection of Zika virus genomes with quantitative RT-PCR and for detection of IgM antibodies with capture-IgM ELISA. We also tested maternal serum...

The New England journal of medicine, Apr 20, 2017

The first cases of a new illness involving fever and rash that was deemed to have been caused by ... more The first cases of a new illness involving fever and rash that was deemed to have been caused by Zika virus (ZIKV) infection in Brazil were reported in 2014, and the presence of the virus was confirmed in April 2015. In October 2015, an unusual increase in the number of cases of microcephaly among newborn infants was reported in Brazil; this disorder was apparently linked to ZIKV infection. From the first investigations of microcephaly, and from subsequent studies in Brazil and elsewhere, it is now clear that ZIKV is a cause of a range of neurologic disorders, including the Guillain-Barré syndrome (GBS) in adults and abnormalities in fetuses and newborn infants, including microcephaly.1 Here, we use routinely collected surveillance data and medical records to show how the spread of ZIKV in Brazil was associated with an increase in the incidence of GBS and microcephaly during 2015 and 2016. We also highlight the limitations of routinely collected data, which cannot yet explain, for example, why there were many fewer cases of microcephaly than expected in 2016. To explore the temporal and geographic distribution of ZIKV infection, we used data provided by municipalities and states in each of the five regions of Brazil, as compiled by the Ministry of Health. These data describe the number of suspected and confirmed cases of ZIKV infection and of cases reported as GBS and microcephaly (Sections 1 and 2 in the Supplementary Appendix, available with the full text of this letter at NEJM.org).

PloS one, 2017

The increased availability of influenza surveillance data in recent years justifies an actual and... more The increased availability of influenza surveillance data in recent years justifies an actual and more complete overview of influenza epidemiology in Latin America. We compared the influenza surveillance systems and assessed the epidemiology of influenza A and B, including the spatio-temporal patterns of influenza epidemics, in ten countries and sub-national regions in Latin America. We aggregated the data by year and country and characteristics of eighty-two years were analysed. We calculated the median proportion of laboratory-confirmed influenza cases caused by each virus strain, and compared the timing and amplitude of the primary and secondary peaks between countries. 37,087 influenza cases were reported during 2004-2012. Influenza A and B accounted for a median of 79% and, respectively, 21% of cases in a year. The percentage of influenza A cases that were subtyped was 82.5%; for influenza B, 15.6% of cases were characterized. Influenza A and B were dominant in seventy-five (91...

Zika virus (ZIKV) transmission in the Americas was first confirmed in May 2015 in Northeast Brazi... more Zika virus (ZIKV) transmission in the Americas was first confirmed in May 2015 in Northeast Brazil1. Brazil has the highest number of reported ZIKV cases worldwide…

Epidemiologia e Serviços de Saúde, 2016

Objective: to describe the first cases of microcephaly possibly related to Zika virus in live bor... more Objective: to describe the first cases of microcephaly possibly related to Zika virus in live born babies reported in the Metropolitan Region of Recife, Pernambuco State, Brazil. Methods: this was a descriptive case series study (cases reported between August 1 st and October 31 st 2015), using medical record data and data from a questionnaire answered by the mothers of the babies. Results: 40 microcephaly cases were confirmed, distributed in eight municipalities within the Metropolitan Region, with Recife itself having the highest concentration of cases (n=12); median head circumference was 29 cm, median chest girth was 31 cm and median weight was 2,628 grams; 21/25 cases had brain calcification, ventriculomegaly or lissencephaly; 27 of the 40 mothers reported rash during pregnancy, 20 in the first trimester and 7 in the second trimester, as well as itching, headache, myalgia and absence of fever. Conclusion: the majority of the cases bore the characteristics of congenital infection; the clinical condition of the majority of mothers suggested Zika virus infection during pregnancy.

The Lancet Infectious Diseases, 2016

Background The microcephaly epidemic, which started in Brazil in 2015, was declared a Public Heal... more Background The microcephaly epidemic, which started in Brazil in 2015, was declared a Public Health Emergency of International Concern by WHO in 2016. We report the preliminary results of a case-control study investigating the association between microcephaly and Zika virus infection during pregnancy. Methods We did this case-control study in eight public hospitals in Recife, Brazil. Cases were neonates with microcephaly. Two controls (neonates without microcephaly), matched by expected date of delivery and area of residence, were selected for each case. Serum samples of cases and controls and cerebrospinal fl uid samples of cases were tested for Zika virus-specifi c IgM and by quantitative RT-PCR. Laboratory-confi rmed Zika virus infection during pregnancy was defi ned as detection of Zika virus-specifi c IgM or a positive RT-PCR result in neonates. Maternal serum samples were tested by plaque reduction neutralisation assay for Zika virus and dengue virus. We estimated crude odds ratios (ORs) and 95% CIs using a median unbiased estimator for binary data in an unconditional logistic regression model. We estimated ORs separately for cases with and without radiological evidence of brain abnormalities. Findings Between Jan 15, 2016, and May 2, 2016, we prospectively recruited 32 cases and 62 controls. 24 (80%) of 30 mothers of cases had Zika virus infection compared with 39 (64%) of 61 mothers of controls (p=0•12). 13 (41%) of 32 cases and none of 62 controls had laboratory-confi rmed Zika virus infection; crude overall OR 55•5 (95% CI 8•6-∞); OR 113•3 (95% CI 14•5-∞) for seven cases with brain abnormalities; and OR 24•7 (95% CI 2•9-∞) for four cases without brain abnormalities. Interpretation Our data suggest that the microcephaly epidemic is a result of congenital Zika virus infection. We await further data from this ongoing study to assess other potential risk factors and to confi rm the strength of association in a larger sample size.

Lancet (London, England), Jan 29, 2016

In November, 2015, an epidemic of microcephaly was reported in Brazil, which was later attributed... more In November, 2015, an epidemic of microcephaly was reported in Brazil, which was later attributed to congenital Zika virus infection. 7830 suspected cases had been reported to the Brazilian Ministry of Health by June 4, 2016, but little is known about their characteristics. We aimed to describe these newborn babies in terms of clinical findings, anthropometry, and survival. We reviewed all 1501 liveborn infants for whom investigation by medical teams at State level had been completed as of Feb 27, 2016, and classified suspected cases into five categories based on neuroimaging and laboratory results for Zika virus and other relevant infections. Definite cases had laboratory evidence of Zika virus infection; highly probable cases presented specific neuroimaging findings, and negative laboratory results for other congenital infections; moderately probable cases had specific imaging findings but other infections could not be ruled out; somewhat probable cases had imaging findings, but t...

Rev Bras Cir Plast, Dec 1, 2009

Epidemiologia e Serviços de Saúde, 2016

MMWR. Morbidity and mortality weekly report, Jan 11, 2016

Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since lat... more Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraíba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of microcephaly. Pregnant women...