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Papers by Hiền Nguyễn Thị Thu

Research paper thumbnail of Depression among inpatients at Hospital of Transportation in 2021 and associated factors

Tạp chí Y tế Công cộng, Dec 30, 2022

Objectives: To describe the depression situation and determine the associated factors of depressi... more Objectives: To describe the depression situation and determine the associated factors of depression among inpatients at Hospital of Transportation. Methods: A cross-sectional study was conducted in December, 2021 with 170 inpatients at Hospital of Transportation using whole sampling techniques. Study information was obtained via the prepared administered questionnaire. The data was entered and analyzed in SPSS version 22.0. Results: The proportion of depression among study subjects was 37.6%, of which 21.1% was the rate of borderline abnormal cases, and 16.5% was of abnormal cases. The depression was found significantly associated with gender, occupation and alcohol consumption. Female inpatients were 2.1 times more likely to experience depression than male (OR = 2.1; CI95%: 1.1 – 4.2; p<0.05). Inpatients who are government officials/businessmen were only 0.44 times more likely to suffer from depression than inpatients who are farmer/self-employed/retired/housewife/no job (OR =0.44; CI95%: 0.2 – 0.9; p<0.05. Inpatients who use alcohol were only 0.43 times more likely to have depression than inpatients who do not use alcohol (OR = 0.43; CI95%: 0.1-0.99, p < 0.05). Conclusions: The study strongly suggested an in-depth investigation to explore the vital identification of the potential risk factors in mental health disorders among patients in the hospital such as acohol consumption, disease situation, duration of disease treatment etc. Also, screening and early detection of cases with signs of depression in order to develop appropriate and effective supportive measures, counseling, and treatment interventions

Research paper thumbnail of Polygonatum kingianum rhizome extract alleviates collagen antibody-induced arthritis by modulating proinflammatory cytokine production in mice

Asian pacific Journal of Tropical Biomedicine, 2020

Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using ... more Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using both in vitro and in vivo models. Methods: Lipopolysaccharide-induced RAW 264.7 macrophages were treated with an ethanol extract of Polygonatum kingianum rhizomes at different concentrations to determine nitric oxide and prostaglandin E2 (PGE2) production. For in vivo study, Polygonatum kingianum ethanol extract was further investigated for its antiinflammatory effect in a mouse model with collagen antibody-induced arthritis. Phytochemical study of Polygonatum kingianum ethanol extract was also performed. Results: Saponins (142 mg/g total yield) was the main component in the Polygonatum kingianum ethanol extract. 5α,8α-ergosterol peroxide, (E,E)-9-oxooctadeca-10,12-dienoic acid and 3-(2’-hydroxy-4’-methoxy-benzyl)-5,7-dihydroxy-8-methyl-chroman-4-one were isolated from the extract. Polygonatum kingianum ethanol extract exhibited potential anti-inflammatory effects by inhibiting nitric oxide and PGE2 production in RAW 264.7 cells in a dose-dependent manner. The level of arthritis in mice with collagen antibody-induced arthritis was significantly reduced (P Conclusions: Polygonatum kingianum ethanol extract has beneficial effects on inflammatory cytokine regulation and PGE2 inhibition in an experimental mouse model with collagen antibody-induced arthritis. The phytochemical screening reveals that the saponin, as the main component, and sterols (daucosterol and 5α,8α-ergosterol peroxide) from Polygonatum kingianum ethanol extract may contribute to its promising in vitro and in vivo anti-inflammatory activities.

Research paper thumbnail of Assessment of the variation on maximum daily heat index in Ninh Binh city

Tạp chí Khoa học Tự nhiên, Mar 1, 2023

Research paper thumbnail of External magnetic field-assisted polarization-dependent optical bistability and multistability in a degenerate two-level EIT medium

Laser Physics Letters, Jan 20, 2023

Research paper thumbnail of Particulate Matter Levels and Elemental Composition in the Spring and Transition Period in Hanoi, Vietnam

Tạp chí Khoa học Tự nhiên, Jun 1, 2022

Research paper thumbnail of CSR motivators of local firms in a developing country: a case study in Quang Ninh province, Vietnam

Journal of International Economics and Management, 2020

This research explores firms' motivators to engage in corporate social responsibility (CSR) actio... more This research explores firms' motivators to engage in corporate social responsibility (CSR) actions from the middle managers' perspective. In-depth interviews were conducted with 27 middle managers from Quang Ninh province in Vietnam. Using Carroll's (1991) CSR pyramid model as the framework for qualitative data analysis, the research finds that, through the middle managers' lens, firms are motivated to engage with CSR for necessity and sufficiency. The necessity components are profitability, competitive advantage, law compliance, and anti-bureaucracy achievements serving as the maintenance factors; and the sufficient components known as encouraging factors include employee retention, ethical image and reputation. The research contributes to the extension of Carroll's (1991) CSR pyramid model to the context of local firms in a developing country.

Research paper thumbnail of ISOLATION OF SOME FLAVONOIDS FROM Vitex trifolia IN BACHMA NATIONAL PARK, THUA THIEN HUE, VIETNAM

Tạp chí Khoa học Tự nhiên, Jun 1, 2019

Research paper thumbnail of Au/TiO2(320)表面における光第二高調波発生に関する研究

Research paper thumbnail of Knowledge, attitude, practice on plastic waste pollution mitigation among undergraduate students in the academic year of 2021 – 2022 and some associated factors

Tạp chí Y tế Công cộng

Objectives: To assess knowledge, attitude, and practice on plastic waste mitigation and associate... more Objectives: To assess knowledge, attitude, and practice on plastic waste mitigation and associated factors among students at Thang Long University and the University of Labour and Social Affairs, Hanoi, Vietnam, in the academic year 2021-2022. Methodology: A cross-sectional study was conducted on 565 undergraduate students at two universities using a stratified random sampling technique. Study subjects were requested to respond online via the administered questionnaire. The questionnaire includes general information (7 questions); knowledge on reducing plastic pollution (13 questions); attitudes on reducing plastic pollution (8 questions); and practice on reducing plastic pollution (10 questions). The reliability of the questionnaire is acceptable (Cronbach's α = 0.610). The data was entered with Excel and then analyzed in SPSS version 22.0. Results: The results revealed that 42.7% of the surveyed students showed adequate knowledge, 97.5% had an adequate attitude, and 82.5% had ...

Research paper thumbnail of Sodium Sulfide-Promoted Reaction of 2-AMINOBENZAMIDE and Benzyl Alcohols with Elemental Sulfur: A Novel Approach with 2-ARYL-QUINAZOLIN-4(3H)

Journal of Science Natural Science

Six derivatives containing benzoxazole were synthesized from phydroxybenzaldehyde via four step-r... more Six derivatives containing benzoxazole were synthesized from phydroxybenzaldehyde via four step-route in high yields. The benzoxazole cyclization step was promoted with microwave irradiation for 10 to 30 min. Free oaminophenol derivative A3 reacted with aldehydes to form benzoxazole A4a-f, but A3.HCl couldn’t due to the presence of iron (II). Their structures were elucidated with spectroscopic methods: IR, 1D, 2D NMR, and MS.

Research paper thumbnail of Synthesis of Some Benzothiazole Aniline Derivatives and Their Biological Activities

Journal of Science Natural Science

Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduc... more Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities.

Research paper thumbnail of Current Biodiversity and the Challenges for Biodiversity Conservation in the Pu Mat National Park

Journal of Science Natural Science

This research synthesizes the most advanced progress on biodiversity in recent decades to develop... more This research synthesizes the most advanced progress on biodiversity in recent decades to develop a set of information about the current condition of biodiversity in the Pu Mat national park. Data was collected from reliable documents nationally, updated statistics, and maps from management committees associated with field surveys in the study area. After implementing data synthesis, analysis, and inheritance from the previous related research and using a geographic information system (GIS), the findings indicated that: 1) Pu Mat National Park protects the rare genetic resources of Vietnam, which include 2600 floral species, 1121 animal species, and four typical ecosystems of evergreen- broadleaf natural forest, mixed wood-bamboo ecosystem, natural bamboo ecosystem and grassshrubs ecosystem; 2) establishing an ecosystem map based on the integration of the forest current maps, forest inventory maps, land use current maps in Pu Mat National Park area, scale 1:50,000; and 3) identifyin...

Research paper thumbnail of Stigmastane-type steroid saponins from the leaves of Vernonia amygdalina and their α-glucosidase and xanthine oxidase inhibitory activities

Natural Product Research

Two new vernonioside K (1) and vernonioside L (2) and four known Δ 7,9(11) stigmastane-type stero... more Two new vernonioside K (1) and vernonioside L (2) and four known Δ 7,9(11) stigmastane-type steroidal saponins-vernonioside B2 (3), vernoniacum B (4), vernonioside B1 (5), and vernoamyoside A (6)were isolated from the leaves of Vernonia amygdalina. Their structures were determined by comprehensive spectroscopic analysis with one-dimensional nuclear magnetic resonance, twodimensional nuclear magnetic resonance, and high-resolution mass spectrometry. All isolated compounds (1-6) were evaluated to determine their inhibitory effects on α-glucosidase and xanthine oxidase. Among them, two new compounds 1 and 2 showed significant inhibition of α-glucosidase with IC 50 values of 78.56 ± 7.28 and 14.74 ± 1.57 (μM), respectively, comparable with acarbose as a positive control (127.53 ± 1.73 μM); none of these compounds inhibited xanthine oxidase activity. Compounds 1 and 2 are promising candidates for the development of antidiabetic agents from natural sources.

Research paper thumbnail of In vitro and in silico cytotoxic activities of triterpenoids from the leaves of Aralia dasyphylla Miq. and the assessment of their ADMET properties

Journal of Biomolecular Structure and Dynamics

Research paper thumbnail of Recovering Capitalization for Automatic Speech Recognition of Vietnamese using Transformer and Chunk Merging

2019 11th International Conference on Knowledge and Systems Engineering (KSE), 2019

In the last few years, Automatic Speech Recognition (ASR) systems for Vietnamese are utilized in ... more In the last few years, Automatic Speech Recognition (ASR) systems for Vietnamese are utilized in various applications with exceptional results. Nevertheless, such ASR output still contains limitations such as the absence of punctuation, capitalization and standardize numeric data. These shortcomings cause difficulties for readers to understand context efficiently and for Natural Language Processing (NLP) tasks to be well-performed. Capitalization is one of the most critical factors to enhance human readability, parsing, and Named Entity Recognition (NER). Additionally, Vietnamese ASR output has its own features comparing to English such as lisp words, local words, compound words, and homophone. In this paper, we propose a method to Recover Capitalization for long-speech ASR transcription of Vietnamese using Transformer models and chunk merging. Furthermore, we perform decoding in parallel while improving the prediction accuracy.

Research paper thumbnail of Xác định Phytosterols trong dầu thực vật bằng sắc ký khí khối phổ GC-MS

Trong nghiên cứu này, phương pháp sắc ký khí khối phổ kết hợp với việc dẫn xuất hóa đã được thẩm ... more Trong nghiên cứu này, phương pháp sắc ký khí khối phổ kết hợp với việc dẫn xuất hóa đã được thẩm định và áp dụng để phân tích đồng thời 6 chất nhóm phytosterol trong dầu thực vật . Mẫu được thủy phân trong tủ ấm 70°C trong 60 phút, rồi được chiết với toluen. Các chất nhóm phytosterol được dẫn xuất với trimethysilyl ether trước khi phân tích trên hệ thống sắc ký khí khối phổ. Giới hạn phát hiện và giới hạn định lượng của phương pháp lần lượt là 5 và 15 mg/kg. Độ thu hồi của cả 6 chất nhóm phytosterol trong khoảng từ 93,5 đến 101%.

Research paper thumbnail of Nghiên cứu ảnh hưởng của lượng phân bón NPK đến sinh trưởng, phát triển và năng suất, chất lượng cây Nghệ vàng Curcuma longa L

Nghiên cứu nhằm đánh giá ảnh hưởng của việc sử dụng phân NPK đến sinh trưởng, phát triển, năng su... more Nghiên cứu nhằm đánh giá ảnh hưởng của việc sử dụng phân NPK đến sinh trưởng, phát triển, năng suất, chất lượng của củ nghệ tại Tuyên Quang. Thí nghiệm thực hiện đối với cây nghệ vàng Curcuma longa L, các công thức thí nghiệm được bố trí theo khối ngẫu nhiên hoàn chỉnh với 3 lần nhắc lại. Kết quả nghiên cứu năm 2018 cho thấy: việc bón phân NPK 5.10.3 có tác động đến quá trình sinh trưởng phát triển, năng suất cũng như hàm lượng Curcumin trong củ nghệ vàng.

Research paper thumbnail of Nghiên cứu tỷ lệ phối trộn giá thể hữu cơ làm bầu ươm cây giống keo lai BV10, BV33 sản xuất bằng phương pháp nuôi cấy mô

SCIENTIFIC JOURNAL OF TAN TRAO UNIVERSITY, 2020

Trong các thành phần của bầu ươm, giá thể và phân bón có vai trò cực kỳ quan trọng. Các loại giá ... more Trong các thành phần của bầu ươm, giá thể và phân bón có vai trò cực kỳ quan trọng. Các loại giá thể như: Cát vàng, xơ dừa, mùn cưa... đã qua xử lý, khi trộn đều với đất nhỏ sẽ làm tăng thêm độ tơi xốp, giúp đất không bị nén lại sau khi tưới nước hoặc để lâu ngày. Một số loại giá thể như xơ dừa, mùn cưa…có khả năng giữ nước rất hiệu quả, giúp cây con trồng trong bầu ươm có sức sống càng cao. Trong nghiên cứu này sử dụng các loại vật liệu như: đất đỏ, phân chuồng hoai mục, mùn cưa, xơ dừa, vôi bột, nước men vi sinh để phối trộn làm giá thể ươm giống keo lai BV10, BV33 sản xuất bằng phương pháp nuôi cấy mô, kết quả nghiên cứu cho thấy: Tỷ lệ phối trộn chất hữu cơ khác nhau làm tăng chiều cao cây và có ý nghĩa trên loại đất nghiên cứu, cụ thể: Chiều cao cây đạt cao nhất ở công thức 5 (18,86 cm) vào giai đoạn 60 ngày sau khi trồng và 31,20 cm vào giai đoạn 90 ngày sau khi trồng. Đường kính cổ rễ: đạt cao nhất ở công thức 5 (1,42 cm) vào giai đoạn 60 ngày sau khi t...

Research paper thumbnail of Utilization of mental health services among university students in Vietnam

International Journal of Mental Health, 2020

This study aimed to describe mental health service utilization and examine associated factors amo... more This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among students participating in our survey, 12.5% (95% CI: 10.9-14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health service utilization were marital status, types of housemate, mental health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stakeholders for improving mental health services utilization among students in Vietnam. These findings had important implications for future research on factors associated with mental health service utilization among university students.

Research paper thumbnail of Case Report: Angiostrongylus cantonensis Meningoencephalitis in a 9-Month-Old Baby in Vietnam

The American Journal of Tropical Medicine and Hygiene, 2020

Meningoencephalitis is not a rare disease in small children. However, eosinophilic meningitis due... more Meningoencephalitis is not a rare disease in small children. However, eosinophilic meningitis due to Angiostrongylus cantonensis is unusual in a baby. We describe the case of a 9-month-old baby from North Vietnam with eosinophilic meningoencephalitis. The baby lived in a rural area, where farming is widespread, and presented with fever and seizures. Laboratory results showed peripheral eosinophilia (16.1%), cerebrospinal fluid (CSF) white blood cell count 220/mm 3 (26% eosinophils), CSF antibody test positive for Ascaris, CSF ELISA positive for Angiostrongylus cantonensis, and blood ELISA positive for A. cantonensis. A mobile worm was identified in the CSF. The presentation was consistent with a diagnosis of A. cantonensis eosinophilic meningitis. The baby recovered fully after administering albendazole (200 mg/day for 2 weeks), and intravenous dexamethasone (0.6 mg/kg/day every 8 hours) and mannitol (1.5 g/kg/day every 8 hours) for the first 3 days, followed by 5 days of oral prednisolone (2 mg/kg/day).

Research paper thumbnail of Depression among inpatients at Hospital of Transportation in 2021 and associated factors

Tạp chí Y tế Công cộng, Dec 30, 2022

Objectives: To describe the depression situation and determine the associated factors of depressi... more Objectives: To describe the depression situation and determine the associated factors of depression among inpatients at Hospital of Transportation. Methods: A cross-sectional study was conducted in December, 2021 with 170 inpatients at Hospital of Transportation using whole sampling techniques. Study information was obtained via the prepared administered questionnaire. The data was entered and analyzed in SPSS version 22.0. Results: The proportion of depression among study subjects was 37.6%, of which 21.1% was the rate of borderline abnormal cases, and 16.5% was of abnormal cases. The depression was found significantly associated with gender, occupation and alcohol consumption. Female inpatients were 2.1 times more likely to experience depression than male (OR = 2.1; CI95%: 1.1 – 4.2; p<0.05). Inpatients who are government officials/businessmen were only 0.44 times more likely to suffer from depression than inpatients who are farmer/self-employed/retired/housewife/no job (OR =0.44; CI95%: 0.2 – 0.9; p<0.05. Inpatients who use alcohol were only 0.43 times more likely to have depression than inpatients who do not use alcohol (OR = 0.43; CI95%: 0.1-0.99, p < 0.05). Conclusions: The study strongly suggested an in-depth investigation to explore the vital identification of the potential risk factors in mental health disorders among patients in the hospital such as acohol consumption, disease situation, duration of disease treatment etc. Also, screening and early detection of cases with signs of depression in order to develop appropriate and effective supportive measures, counseling, and treatment interventions

Research paper thumbnail of Polygonatum kingianum rhizome extract alleviates collagen antibody-induced arthritis by modulating proinflammatory cytokine production in mice

Asian pacific Journal of Tropical Biomedicine, 2020

Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using ... more Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using both in vitro and in vivo models. Methods: Lipopolysaccharide-induced RAW 264.7 macrophages were treated with an ethanol extract of Polygonatum kingianum rhizomes at different concentrations to determine nitric oxide and prostaglandin E2 (PGE2) production. For in vivo study, Polygonatum kingianum ethanol extract was further investigated for its antiinflammatory effect in a mouse model with collagen antibody-induced arthritis. Phytochemical study of Polygonatum kingianum ethanol extract was also performed. Results: Saponins (142 mg/g total yield) was the main component in the Polygonatum kingianum ethanol extract. 5α,8α-ergosterol peroxide, (E,E)-9-oxooctadeca-10,12-dienoic acid and 3-(2’-hydroxy-4’-methoxy-benzyl)-5,7-dihydroxy-8-methyl-chroman-4-one were isolated from the extract. Polygonatum kingianum ethanol extract exhibited potential anti-inflammatory effects by inhibiting nitric oxide and PGE2 production in RAW 264.7 cells in a dose-dependent manner. The level of arthritis in mice with collagen antibody-induced arthritis was significantly reduced (P Conclusions: Polygonatum kingianum ethanol extract has beneficial effects on inflammatory cytokine regulation and PGE2 inhibition in an experimental mouse model with collagen antibody-induced arthritis. The phytochemical screening reveals that the saponin, as the main component, and sterols (daucosterol and 5α,8α-ergosterol peroxide) from Polygonatum kingianum ethanol extract may contribute to its promising in vitro and in vivo anti-inflammatory activities.

Research paper thumbnail of Assessment of the variation on maximum daily heat index in Ninh Binh city

Tạp chí Khoa học Tự nhiên, Mar 1, 2023

Research paper thumbnail of External magnetic field-assisted polarization-dependent optical bistability and multistability in a degenerate two-level EIT medium

Laser Physics Letters, Jan 20, 2023

Research paper thumbnail of Particulate Matter Levels and Elemental Composition in the Spring and Transition Period in Hanoi, Vietnam

Tạp chí Khoa học Tự nhiên, Jun 1, 2022

Research paper thumbnail of CSR motivators of local firms in a developing country: a case study in Quang Ninh province, Vietnam

Journal of International Economics and Management, 2020

This research explores firms' motivators to engage in corporate social responsibility (CSR) actio... more This research explores firms' motivators to engage in corporate social responsibility (CSR) actions from the middle managers' perspective. In-depth interviews were conducted with 27 middle managers from Quang Ninh province in Vietnam. Using Carroll's (1991) CSR pyramid model as the framework for qualitative data analysis, the research finds that, through the middle managers' lens, firms are motivated to engage with CSR for necessity and sufficiency. The necessity components are profitability, competitive advantage, law compliance, and anti-bureaucracy achievements serving as the maintenance factors; and the sufficient components known as encouraging factors include employee retention, ethical image and reputation. The research contributes to the extension of Carroll's (1991) CSR pyramid model to the context of local firms in a developing country.

Research paper thumbnail of ISOLATION OF SOME FLAVONOIDS FROM Vitex trifolia IN BACHMA NATIONAL PARK, THUA THIEN HUE, VIETNAM

Tạp chí Khoa học Tự nhiên, Jun 1, 2019

Research paper thumbnail of Au/TiO2(320)表面における光第二高調波発生に関する研究

Research paper thumbnail of Knowledge, attitude, practice on plastic waste pollution mitigation among undergraduate students in the academic year of 2021 – 2022 and some associated factors

Tạp chí Y tế Công cộng

Objectives: To assess knowledge, attitude, and practice on plastic waste mitigation and associate... more Objectives: To assess knowledge, attitude, and practice on plastic waste mitigation and associated factors among students at Thang Long University and the University of Labour and Social Affairs, Hanoi, Vietnam, in the academic year 2021-2022. Methodology: A cross-sectional study was conducted on 565 undergraduate students at two universities using a stratified random sampling technique. Study subjects were requested to respond online via the administered questionnaire. The questionnaire includes general information (7 questions); knowledge on reducing plastic pollution (13 questions); attitudes on reducing plastic pollution (8 questions); and practice on reducing plastic pollution (10 questions). The reliability of the questionnaire is acceptable (Cronbach's α = 0.610). The data was entered with Excel and then analyzed in SPSS version 22.0. Results: The results revealed that 42.7% of the surveyed students showed adequate knowledge, 97.5% had an adequate attitude, and 82.5% had ...

Research paper thumbnail of Sodium Sulfide-Promoted Reaction of 2-AMINOBENZAMIDE and Benzyl Alcohols with Elemental Sulfur: A Novel Approach with 2-ARYL-QUINAZOLIN-4(3H)

Journal of Science Natural Science

Six derivatives containing benzoxazole were synthesized from phydroxybenzaldehyde via four step-r... more Six derivatives containing benzoxazole were synthesized from phydroxybenzaldehyde via four step-route in high yields. The benzoxazole cyclization step was promoted with microwave irradiation for 10 to 30 min. Free oaminophenol derivative A3 reacted with aldehydes to form benzoxazole A4a-f, but A3.HCl couldn’t due to the presence of iron (II). Their structures were elucidated with spectroscopic methods: IR, 1D, 2D NMR, and MS.

Research paper thumbnail of Synthesis of Some Benzothiazole Aniline Derivatives and Their Biological Activities

Journal of Science Natural Science

Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduc... more Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities.

Research paper thumbnail of Current Biodiversity and the Challenges for Biodiversity Conservation in the Pu Mat National Park

Journal of Science Natural Science

This research synthesizes the most advanced progress on biodiversity in recent decades to develop... more This research synthesizes the most advanced progress on biodiversity in recent decades to develop a set of information about the current condition of biodiversity in the Pu Mat national park. Data was collected from reliable documents nationally, updated statistics, and maps from management committees associated with field surveys in the study area. After implementing data synthesis, analysis, and inheritance from the previous related research and using a geographic information system (GIS), the findings indicated that: 1) Pu Mat National Park protects the rare genetic resources of Vietnam, which include 2600 floral species, 1121 animal species, and four typical ecosystems of evergreen- broadleaf natural forest, mixed wood-bamboo ecosystem, natural bamboo ecosystem and grassshrubs ecosystem; 2) establishing an ecosystem map based on the integration of the forest current maps, forest inventory maps, land use current maps in Pu Mat National Park area, scale 1:50,000; and 3) identifyin...

Research paper thumbnail of Stigmastane-type steroid saponins from the leaves of Vernonia amygdalina and their α-glucosidase and xanthine oxidase inhibitory activities

Natural Product Research

Two new vernonioside K (1) and vernonioside L (2) and four known Δ 7,9(11) stigmastane-type stero... more Two new vernonioside K (1) and vernonioside L (2) and four known Δ 7,9(11) stigmastane-type steroidal saponins-vernonioside B2 (3), vernoniacum B (4), vernonioside B1 (5), and vernoamyoside A (6)were isolated from the leaves of Vernonia amygdalina. Their structures were determined by comprehensive spectroscopic analysis with one-dimensional nuclear magnetic resonance, twodimensional nuclear magnetic resonance, and high-resolution mass spectrometry. All isolated compounds (1-6) were evaluated to determine their inhibitory effects on α-glucosidase and xanthine oxidase. Among them, two new compounds 1 and 2 showed significant inhibition of α-glucosidase with IC 50 values of 78.56 ± 7.28 and 14.74 ± 1.57 (μM), respectively, comparable with acarbose as a positive control (127.53 ± 1.73 μM); none of these compounds inhibited xanthine oxidase activity. Compounds 1 and 2 are promising candidates for the development of antidiabetic agents from natural sources.

Research paper thumbnail of In vitro and in silico cytotoxic activities of triterpenoids from the leaves of Aralia dasyphylla Miq. and the assessment of their ADMET properties

Journal of Biomolecular Structure and Dynamics

Research paper thumbnail of Recovering Capitalization for Automatic Speech Recognition of Vietnamese using Transformer and Chunk Merging

2019 11th International Conference on Knowledge and Systems Engineering (KSE), 2019

In the last few years, Automatic Speech Recognition (ASR) systems for Vietnamese are utilized in ... more In the last few years, Automatic Speech Recognition (ASR) systems for Vietnamese are utilized in various applications with exceptional results. Nevertheless, such ASR output still contains limitations such as the absence of punctuation, capitalization and standardize numeric data. These shortcomings cause difficulties for readers to understand context efficiently and for Natural Language Processing (NLP) tasks to be well-performed. Capitalization is one of the most critical factors to enhance human readability, parsing, and Named Entity Recognition (NER). Additionally, Vietnamese ASR output has its own features comparing to English such as lisp words, local words, compound words, and homophone. In this paper, we propose a method to Recover Capitalization for long-speech ASR transcription of Vietnamese using Transformer models and chunk merging. Furthermore, we perform decoding in parallel while improving the prediction accuracy.

Research paper thumbnail of Xác định Phytosterols trong dầu thực vật bằng sắc ký khí khối phổ GC-MS

Trong nghiên cứu này, phương pháp sắc ký khí khối phổ kết hợp với việc dẫn xuất hóa đã được thẩm ... more Trong nghiên cứu này, phương pháp sắc ký khí khối phổ kết hợp với việc dẫn xuất hóa đã được thẩm định và áp dụng để phân tích đồng thời 6 chất nhóm phytosterol trong dầu thực vật . Mẫu được thủy phân trong tủ ấm 70°C trong 60 phút, rồi được chiết với toluen. Các chất nhóm phytosterol được dẫn xuất với trimethysilyl ether trước khi phân tích trên hệ thống sắc ký khí khối phổ. Giới hạn phát hiện và giới hạn định lượng của phương pháp lần lượt là 5 và 15 mg/kg. Độ thu hồi của cả 6 chất nhóm phytosterol trong khoảng từ 93,5 đến 101%.

Research paper thumbnail of Nghiên cứu ảnh hưởng của lượng phân bón NPK đến sinh trưởng, phát triển và năng suất, chất lượng cây Nghệ vàng Curcuma longa L

Nghiên cứu nhằm đánh giá ảnh hưởng của việc sử dụng phân NPK đến sinh trưởng, phát triển, năng su... more Nghiên cứu nhằm đánh giá ảnh hưởng của việc sử dụng phân NPK đến sinh trưởng, phát triển, năng suất, chất lượng của củ nghệ tại Tuyên Quang. Thí nghiệm thực hiện đối với cây nghệ vàng Curcuma longa L, các công thức thí nghiệm được bố trí theo khối ngẫu nhiên hoàn chỉnh với 3 lần nhắc lại. Kết quả nghiên cứu năm 2018 cho thấy: việc bón phân NPK 5.10.3 có tác động đến quá trình sinh trưởng phát triển, năng suất cũng như hàm lượng Curcumin trong củ nghệ vàng.

Research paper thumbnail of Nghiên cứu tỷ lệ phối trộn giá thể hữu cơ làm bầu ươm cây giống keo lai BV10, BV33 sản xuất bằng phương pháp nuôi cấy mô

SCIENTIFIC JOURNAL OF TAN TRAO UNIVERSITY, 2020

Trong các thành phần của bầu ươm, giá thể và phân bón có vai trò cực kỳ quan trọng. Các loại giá ... more Trong các thành phần của bầu ươm, giá thể và phân bón có vai trò cực kỳ quan trọng. Các loại giá thể như: Cát vàng, xơ dừa, mùn cưa... đã qua xử lý, khi trộn đều với đất nhỏ sẽ làm tăng thêm độ tơi xốp, giúp đất không bị nén lại sau khi tưới nước hoặc để lâu ngày. Một số loại giá thể như xơ dừa, mùn cưa…có khả năng giữ nước rất hiệu quả, giúp cây con trồng trong bầu ươm có sức sống càng cao. Trong nghiên cứu này sử dụng các loại vật liệu như: đất đỏ, phân chuồng hoai mục, mùn cưa, xơ dừa, vôi bột, nước men vi sinh để phối trộn làm giá thể ươm giống keo lai BV10, BV33 sản xuất bằng phương pháp nuôi cấy mô, kết quả nghiên cứu cho thấy: Tỷ lệ phối trộn chất hữu cơ khác nhau làm tăng chiều cao cây và có ý nghĩa trên loại đất nghiên cứu, cụ thể: Chiều cao cây đạt cao nhất ở công thức 5 (18,86 cm) vào giai đoạn 60 ngày sau khi trồng và 31,20 cm vào giai đoạn 90 ngày sau khi trồng. Đường kính cổ rễ: đạt cao nhất ở công thức 5 (1,42 cm) vào giai đoạn 60 ngày sau khi t...

Research paper thumbnail of Utilization of mental health services among university students in Vietnam

International Journal of Mental Health, 2020

This study aimed to describe mental health service utilization and examine associated factors amo... more This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among students participating in our survey, 12.5% (95% CI: 10.9-14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health service utilization were marital status, types of housemate, mental health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stakeholders for improving mental health services utilization among students in Vietnam. These findings had important implications for future research on factors associated with mental health service utilization among university students.

Research paper thumbnail of Case Report: Angiostrongylus cantonensis Meningoencephalitis in a 9-Month-Old Baby in Vietnam

The American Journal of Tropical Medicine and Hygiene, 2020

Meningoencephalitis is not a rare disease in small children. However, eosinophilic meningitis due... more Meningoencephalitis is not a rare disease in small children. However, eosinophilic meningitis due to Angiostrongylus cantonensis is unusual in a baby. We describe the case of a 9-month-old baby from North Vietnam with eosinophilic meningoencephalitis. The baby lived in a rural area, where farming is widespread, and presented with fever and seizures. Laboratory results showed peripheral eosinophilia (16.1%), cerebrospinal fluid (CSF) white blood cell count 220/mm 3 (26% eosinophils), CSF antibody test positive for Ascaris, CSF ELISA positive for Angiostrongylus cantonensis, and blood ELISA positive for A. cantonensis. A mobile worm was identified in the CSF. The presentation was consistent with a diagnosis of A. cantonensis eosinophilic meningitis. The baby recovered fully after administering albendazole (200 mg/day for 2 weeks), and intravenous dexamethasone (0.6 mg/kg/day every 8 hours) and mannitol (1.5 g/kg/day every 8 hours) for the first 3 days, followed by 5 days of oral prednisolone (2 mg/kg/day).