Himangi Vig - Academia.edu (original) (raw)
Papers by Himangi Vig
Asian pacific journal of reproduction, 2022
Advanced Pharmaceutical Bulletin, Oct 13, 2023
The Open Medicinal Chemistry Journal, Dec 28, 2023
Background: The majority of foods, vegetation, plankton, and photosynthetic bacteria all include ... more Background: The majority of foods, vegetation, plankton, and photosynthetic bacteria all include carotenoids, which are pigments that naturally exist. Since humans are unable to produce carotenoids, they must be consumed through food or supplements. There are many roles for carotenoids in ensuring human health. They generally act as antioxidants, but different carotenoids may also have other functions. For instance, β-carotene functions as pro-vitamin A, while lutein and zeaxanthin make up the macular pigmentation in the eyes.
Current Drug Discovery Technologies
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of moto... more Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of motor, cognitive, and psychomotor dysfunctions. The current pharmaceutical treatment focuses on treating the condition's symptoms. They are primarily concerned with reducing illness symptoms or avoiding dopamine metabolism. As our understanding of disease pathogenesis improves, new therapeutic approaches emerge. Objective: This article aims to describe the standard Parkinson's medications based on symptoms and requirements. It emphasizes recent advancements in symptomatic therapy for motor indications and achievements in the research and clinical testing of medicines that promise to enable disease modification in patients with already-manifest PD. Methods: Information for this paper was found by looking through Google Scholar and reading several research and review articles from Bentham Science, Science Direct, Elsevier, Frontiers, Taylor & Francis, and other publishers. Result: Park...
Current Aging Science
Background: Parkinson's disease is a complicated, gradually progressive neurological illness ... more Background: Parkinson's disease is a complicated, gradually progressive neurological illness characterized by locomotor and non-motor symptomatology that impedes daily activities. Despite significant advances in symptomatic therapies with various extents of negative effects, there are currently no disease-modifying medicinal alternatives. Symptoms worsen, creating an additional strain that reduces living quality and creates the perception that prescription drugs are no longer productive. Objective: Adopting healthy lifestyle habits can help patients feel more empowered, promote wellness, relieve symptoms, and potentially slow neurodegeneration. Nutrition, intellectual stimulation, physical exercise, and stress reduction are all examples of lifestyle habits that improve cognitive health and life satisfaction. We discuss how changes in lifestyle, nutrition, yoga, exercise, and acupuncture can help with managing the disease's symptoms. Method: We searched Google Scholar for var...
Current Diabetes Reviews
Background: The existence of aberrant myocardial activity and function in the exclusion of those ... more Background: The existence of aberrant myocardial activity and function in the exclusion of those other cardiovascular events, such as atherosclerosis, hypertension, and severe valve disease, is known as diabetic cardiomyopathy. Diabetes patients are much more prone to death from cardiovascular illnesses than from any other cause, and they also have a 2–5 fold higher likelihood of acquiring cardiac failure and other complications. Objective: In this review, the pathophysiology of diabetic cardiomyopathy is discussed, with an emphasis on the molecular and cellular irregularities that arise as the condition progresses, as well as existing and prospective future treatments. Method: The literature for this topic was researched utilizing Google Scholar as a search engine. Before compiling the review article, several research and review publications from various publishers, including Bentham Science, Nature, Frontiers, and Elsevier, were investigated. Result: The abnormal cardiac remodelli...
Current Drug Discovery Technologies
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of moto... more Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of motor, cognitive, and psychomotor dysfunctions. The current pharmaceutical treatment focuses on treating the condition's symptoms. They are primarily concerned with reducing illness symptoms or avoiding dopamine metabolism. As our understanding of disease pathogenesis improves, new therapeutic approaches emerge. Objective: This article aims to describe the standard Parkinson's medications based on symptoms and requirements. It emphasizes recent advancements in symptomatic therapy for motor indications and achievements in the research and clinical testing of medicines that promise to enable disease modification in patients with already-manifest PD. Methods: Information for this paper was found by looking through Google Scholar and reading several research and review articles from Bentham Science, Science Direct, Elsevier, Frontiers, Taylor & Francis, and other publishers. Result: Park...
Pharmacophore, 2022
Niosomes increase drug bioavailability and address issues with drug insolubility, instability, ra... more Niosomes increase drug bioavailability and address issues with drug insolubility, instability, rapid degradation, and lower treatment costs. By incorporating herbal medications into the delivery method, niosomes are created to enhance their toxicity protection, sustained delivery, pharmacological action, tissue macrophage distributions, and resilience to chemical and physical deterioration. By limiting a drug's activity to its intended target cells, niosomes make it less toxic and raise its therapeutic index. Niosomes, a novel medication delivery method, help increase therapeutic effects while decreasing adverse effects in herbal compositions. This study's goal is to draw attention to the use of phytoniosomes. Niosomes, a new type of drug delivery vehicle, are useful in herbal formulations because they lessen toxic effects while enhancing therapeutic effects. This article reveals details regarding niosomes and the use of herbs in niosomes. To acquire the data for the aforementioned study, research and review publications from different publishers, including Hindawi, Elsevier, Springer Nature, and Bentham Science, were examined using Google Scholar as a search engine. Herbal medicines containing water-soluble phytoconstituents are less absorbed due to their large molecular mass and less lipid solubility. To overcome these drawbacks, numerous experiments are being done that try to incorporate herbal components into cutting-edge pharmaceutical delivery systems like niosomes. Improvements in stability and pharmacological activity, are also brought about by the formulation of phytoniosomes. Numerous studies employing different phytoniosome have been conducted. However, more studies are required to gauge the potency of the phytoniosome using a variety of herbs.
Archives of Pharmacy Practice
Current Reviews in Clinical and Experimental Pharmacology
Background: Parkinson's disease is the second most common neurological ailment. It is also kn... more Background: Parkinson's disease is the second most common neurological ailment. It is also known that it affects practically all other brain components, although only gradually. Animal models are mostly used to test the efficacy of treatment against a specific enzyme and to aid in the creation of a new drug dose. Objective: The purpose of this review paper is to highlight in vivo Parkinson's disease screening approaches, as well as the mechanism of action of each drug involved in Parkinson's disease development, and discuss the limitations of each model. In addition, also sheds light on Parkinson's disease genetic models. Method: The data for the publication was gathered from databases such as PubMed, Bentham Science, Elsevier, Springer Nature, Wiley, and Research Gate after a thorough examination of diverse research findings linked to Parkinson’s disease and its screening models. Result: Each chemical or drug has a unique mechanism for causing disease, whether it...
Future Journal of Pharmaceutical Sciences
Background The loss of dopamine neurons in the substantia nigra, as well as other mostly catechol... more Background The loss of dopamine neurons in the substantia nigra, as well as other mostly catecholaminergic neurons, causes many of the motor symptoms that define Parkinson's disease. Parkinson's disease is commonly thought of as a movement disorder, the significant prevalence of psychiatric complications such as cognitive impairment, and psychosis suggests it should be considered a neuropsychiatric illness, and all behavioral complications are linked to growing disability and the medication. Main body Apart from the disease-induced abnormalities, there are several other side effects of the disease and also from the medication used to prevent the disease. This article focuses on the pathogenesis of Parkinson’s disease and also the behavioral abnormalities caused by the disease and its medication. The study's data were gathered by searching several review articles and research papers from a variety of sources, including Elsevier, PubMed, Research Gate, Journal of Pharmaceu...
International Journal of Pharmaceutical Investigation
Current Drug Therapy, Mar 28, 2022
Asian pacific journal of reproduction, 2022
Advanced Pharmaceutical Bulletin, Oct 13, 2023
The Open Medicinal Chemistry Journal, Dec 28, 2023
Background: The majority of foods, vegetation, plankton, and photosynthetic bacteria all include ... more Background: The majority of foods, vegetation, plankton, and photosynthetic bacteria all include carotenoids, which are pigments that naturally exist. Since humans are unable to produce carotenoids, they must be consumed through food or supplements. There are many roles for carotenoids in ensuring human health. They generally act as antioxidants, but different carotenoids may also have other functions. For instance, β-carotene functions as pro-vitamin A, while lutein and zeaxanthin make up the macular pigmentation in the eyes.
Current Drug Discovery Technologies
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of moto... more Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of motor, cognitive, and psychomotor dysfunctions. The current pharmaceutical treatment focuses on treating the condition's symptoms. They are primarily concerned with reducing illness symptoms or avoiding dopamine metabolism. As our understanding of disease pathogenesis improves, new therapeutic approaches emerge. Objective: This article aims to describe the standard Parkinson's medications based on symptoms and requirements. It emphasizes recent advancements in symptomatic therapy for motor indications and achievements in the research and clinical testing of medicines that promise to enable disease modification in patients with already-manifest PD. Methods: Information for this paper was found by looking through Google Scholar and reading several research and review articles from Bentham Science, Science Direct, Elsevier, Frontiers, Taylor & Francis, and other publishers. Result: Park...
Current Aging Science
Background: Parkinson's disease is a complicated, gradually progressive neurological illness ... more Background: Parkinson's disease is a complicated, gradually progressive neurological illness characterized by locomotor and non-motor symptomatology that impedes daily activities. Despite significant advances in symptomatic therapies with various extents of negative effects, there are currently no disease-modifying medicinal alternatives. Symptoms worsen, creating an additional strain that reduces living quality and creates the perception that prescription drugs are no longer productive. Objective: Adopting healthy lifestyle habits can help patients feel more empowered, promote wellness, relieve symptoms, and potentially slow neurodegeneration. Nutrition, intellectual stimulation, physical exercise, and stress reduction are all examples of lifestyle habits that improve cognitive health and life satisfaction. We discuss how changes in lifestyle, nutrition, yoga, exercise, and acupuncture can help with managing the disease's symptoms. Method: We searched Google Scholar for var...
Current Diabetes Reviews
Background: The existence of aberrant myocardial activity and function in the exclusion of those ... more Background: The existence of aberrant myocardial activity and function in the exclusion of those other cardiovascular events, such as atherosclerosis, hypertension, and severe valve disease, is known as diabetic cardiomyopathy. Diabetes patients are much more prone to death from cardiovascular illnesses than from any other cause, and they also have a 2–5 fold higher likelihood of acquiring cardiac failure and other complications. Objective: In this review, the pathophysiology of diabetic cardiomyopathy is discussed, with an emphasis on the molecular and cellular irregularities that arise as the condition progresses, as well as existing and prospective future treatments. Method: The literature for this topic was researched utilizing Google Scholar as a search engine. Before compiling the review article, several research and review publications from various publishers, including Bentham Science, Nature, Frontiers, and Elsevier, were investigated. Result: The abnormal cardiac remodelli...
Current Drug Discovery Technologies
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of moto... more Background: Parkinson’s disease (PD) is a neurodegenerative syndrome defined by a variety of motor, cognitive, and psychomotor dysfunctions. The current pharmaceutical treatment focuses on treating the condition's symptoms. They are primarily concerned with reducing illness symptoms or avoiding dopamine metabolism. As our understanding of disease pathogenesis improves, new therapeutic approaches emerge. Objective: This article aims to describe the standard Parkinson's medications based on symptoms and requirements. It emphasizes recent advancements in symptomatic therapy for motor indications and achievements in the research and clinical testing of medicines that promise to enable disease modification in patients with already-manifest PD. Methods: Information for this paper was found by looking through Google Scholar and reading several research and review articles from Bentham Science, Science Direct, Elsevier, Frontiers, Taylor & Francis, and other publishers. Result: Park...
Pharmacophore, 2022
Niosomes increase drug bioavailability and address issues with drug insolubility, instability, ra... more Niosomes increase drug bioavailability and address issues with drug insolubility, instability, rapid degradation, and lower treatment costs. By incorporating herbal medications into the delivery method, niosomes are created to enhance their toxicity protection, sustained delivery, pharmacological action, tissue macrophage distributions, and resilience to chemical and physical deterioration. By limiting a drug's activity to its intended target cells, niosomes make it less toxic and raise its therapeutic index. Niosomes, a novel medication delivery method, help increase therapeutic effects while decreasing adverse effects in herbal compositions. This study's goal is to draw attention to the use of phytoniosomes. Niosomes, a new type of drug delivery vehicle, are useful in herbal formulations because they lessen toxic effects while enhancing therapeutic effects. This article reveals details regarding niosomes and the use of herbs in niosomes. To acquire the data for the aforementioned study, research and review publications from different publishers, including Hindawi, Elsevier, Springer Nature, and Bentham Science, were examined using Google Scholar as a search engine. Herbal medicines containing water-soluble phytoconstituents are less absorbed due to their large molecular mass and less lipid solubility. To overcome these drawbacks, numerous experiments are being done that try to incorporate herbal components into cutting-edge pharmaceutical delivery systems like niosomes. Improvements in stability and pharmacological activity, are also brought about by the formulation of phytoniosomes. Numerous studies employing different phytoniosome have been conducted. However, more studies are required to gauge the potency of the phytoniosome using a variety of herbs.
Archives of Pharmacy Practice
Current Reviews in Clinical and Experimental Pharmacology
Background: Parkinson's disease is the second most common neurological ailment. It is also kn... more Background: Parkinson's disease is the second most common neurological ailment. It is also known that it affects practically all other brain components, although only gradually. Animal models are mostly used to test the efficacy of treatment against a specific enzyme and to aid in the creation of a new drug dose. Objective: The purpose of this review paper is to highlight in vivo Parkinson's disease screening approaches, as well as the mechanism of action of each drug involved in Parkinson's disease development, and discuss the limitations of each model. In addition, also sheds light on Parkinson's disease genetic models. Method: The data for the publication was gathered from databases such as PubMed, Bentham Science, Elsevier, Springer Nature, Wiley, and Research Gate after a thorough examination of diverse research findings linked to Parkinson’s disease and its screening models. Result: Each chemical or drug has a unique mechanism for causing disease, whether it...
Future Journal of Pharmaceutical Sciences
Background The loss of dopamine neurons in the substantia nigra, as well as other mostly catechol... more Background The loss of dopamine neurons in the substantia nigra, as well as other mostly catecholaminergic neurons, causes many of the motor symptoms that define Parkinson's disease. Parkinson's disease is commonly thought of as a movement disorder, the significant prevalence of psychiatric complications such as cognitive impairment, and psychosis suggests it should be considered a neuropsychiatric illness, and all behavioral complications are linked to growing disability and the medication. Main body Apart from the disease-induced abnormalities, there are several other side effects of the disease and also from the medication used to prevent the disease. This article focuses on the pathogenesis of Parkinson’s disease and also the behavioral abnormalities caused by the disease and its medication. The study's data were gathered by searching several review articles and research papers from a variety of sources, including Elsevier, PubMed, Research Gate, Journal of Pharmaceu...
International Journal of Pharmaceutical Investigation
Current Drug Therapy, Mar 28, 2022