Hoda Baghdadi - Academia.edu (original) (raw)

Papers by Hoda Baghdadi

Research paper thumbnail of The protective effect of Coriandrum sativum L . oil against liver toxicity induced by Ibuprofen in rats

Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and... more Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and in inflammation.Coriandrum sativum is cultivated for its aromatic and medicinal uses. The present study aims to evaluatethe protective effect of Coriandrum sativum volatile oil on hepatotoxicityof IBU in rats. Five groups of albino rats were used.Group l(control),groupll (C.sativum oil,40 mg/kg B.W. for 14 day), group lll (IBU group,100mg/kg bodyweight B.W., for 14 day), group lV (IBU+ C.sativum oil) and groupV (recovery group).The activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in the liver of different groups addition to the histological examination of the sections of liver. The results showed that IBU caused a significant decrease in the activity of ALT and AST in the liver. The histological examination of the liver showed many pathological changes. Administration of coriander volatile oilin the combination with IBU was able to significan...

Research paper thumbnail of The protective effect of Coriandrum sativum L. oil against liver toxicity induced by Ibuprofen in rats

Journal of Bioscience and Applied Research

Research paper thumbnail of Antibacterial Activity of Plants Essential Oils Against Some Epidemiologically Relevant Food-Borne Pathogens

The Open Public Health Journal, 2015

Research paper thumbnail of Oxidative stress modulation by R osmarinus officinalis in creosote-induced hepatotoxicity

Environmental Toxicology, 2014

Research paper thumbnail of Cross Sectional Study of Skin Carriage and Enterotoxigenicity of Staphylococcus aureus among Food Handlers

Open Journal of Medical Microbiology, 2014

Research paper thumbnail of Adsorption mechanisms of nicotine on humic acid and clay humic acid complex

Zeitschrift für Pflanzenernährung und Bodenkunde, 1990

Page 1. 33 Adsorption mechanisms of nicotine on humic acid and clay humic acid complex Ahmed H. K... more Page 1. 33 Adsorption mechanisms of nicotine on humic acid and clay humic acid complex Ahmed H. Khairy, Hoda H. Baghdadi and Elham A. Ghabbour Institute of Graduate Studies and Research, Alexandria University, PO Box 832, El-Shatby, Alexandria, Egypt ...

Research paper thumbnail of Comparison between biological and chemical treatment of wastewater containing nitrogen and phosphorus

Journal of Industrial Microbiology & Biotechnology, 2005

Research paper thumbnail of Effect of Isoflavones on Reproductive Performance, Testosterone Levels, Lipid Peroxidation, and Seminal Plasma Biochemistry of Male Rabbits

Journal of Environmental Science and Health, Part B- Pesticides, Food Contaminants, and Agricultural Wastes, 2004

The objective of this study was to determine the effect of either 2.5 mg/kg Body Weight or 5 mg/k... more The objective of this study was to determine the effect of either 2.5 mg/kg Body Weight or 5 mg/kg Body Weight (BW) doses of isoflavones on semen quality, testosterone levels, lipid peroxidation and semen biochemistry of male New Zealand White rabbits. Animals were given both 2.5 mg/kg BW and 5 mg/kg BW doses of isoflavones. The tested doses were given to rabbits orally every other day for 13 weeks. Treatment with isoflavones caused an increase (p < 0.05) in libido (by decreasing the reaction time), sperm concentration, sperm motility (%), total motile sperm per ejaculate (TMS), packed sperm volume (PSV), total functional sperm fraction (TFSF), total sperm output, initial fructose concentration and normal sperm, while dead sperm was reduced compared to control animals. On the other hand, ejaculate volume, initial hydrogen ion concentration (pH) and plasma testosterone levels did not change in treated animals with both doses of isoflavones as compared to control. Concentrations of thiobarbituric acid-reactive substances (TBARS), total lipids, and low density lipoprotein were significantly (p < 0.05) reduced in seminal plasma of rabbits treated with either 2.5 mg/kg BW or 5 mg/kg BW doses of isoflavones. While, the activities of glutathione S-transferase (GST), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alanine aminotransferase (ALT), acid phosphatase (AcP), and alkaline phosphatase (AlP) were significantly (p < 0.05) increased in seminal plasma of treated animals. Also, total cholesterol, percentage cholesterol (out of total lipids), and high density lipoprotein were significantly (p < 0.05) increased, while triglyceride did not change in seminal plasma of treated animals. Supplementation at either level of isoflavones did not cause changes in live body weight (LBW), dry matter intake (DMI), and relative weights of testes and epididymis. The present results showed that either 2.5 mg/kg BW or 5 mg/kg BW doses of isoflavones caused an improvement of some semen characteristics and did not have negative effects on male fertility.

Research paper thumbnail of Role of α-Tocopherol and β-Carotene in Ameliorating the Fenvalerate-Induced Changes in Oxidative Stress, Hemato-Biochemical Parameters, and Semen Quality of Male Rats

Journal of Environmental Science and Health, Part B, 2004

Abstract Role of α-tocopherol (vitamin E), β-carotene and/or their combination as antioxidants ag... more Abstract Role of α-tocopherol (vitamin E), β-carotene and/or their combination as antioxidants against the toxicity of fenvalerate on blood hematology, free radicals, biochemical parameters, and semen quality were studied in male rats. Fenvalerate (20 mg ...

Research paper thumbnail of Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and β-carotene

Food and Chemical Toxicology, 2004

Cadmium is a well-known human carcinogen and a potent nephrotoxin. Lipid peroxidation is involved... more Cadmium is a well-known human carcinogen and a potent nephrotoxin. Lipid peroxidation is involved in cadmium-related toxicity. Vitamin E and beta-carotene are effective antioxidants and free radical scavengers. Therefore, the present study was carried out to investigate the potential protective effects of vitamin E and beta-carotene alone or in combination against cadmium (Cd) toxicity. Cadmium chloride (CdCl2, 5 mg/kg BW, 1/15 LD50), vitamin E (100 mg/kg BW), beta-carotene (10 mg/kg BW), and vitamin E with beta-carotene (100 + 10 mg/kg BW, respectively) were orally administered by gavage alone or in combination. The tested doses were given to rats every other day (15 times). Results obtained showed that CdCl2 significantly (P < 0.05) induced free radicals in plasma, liver and brain. The activities of glutathione S-transferase (GST) (plasma and liver), alkaline phosphatase (AlP) (plasma and liver), aspartate aminotransferase (AST), alanine aminotransferase (ALT) (liver) and acetylcholinesterase (AChE) (plasma and brain) were significantly (P < 0.05) decreased due to CdCl2 administration, whereas, the activities of AST and ALT were increased in plasma. Treatment with CdCl2 caused a significant (P < 0.05) increase in glucose, urea, creatinine and bilirubin in plasma. On the other hand, results showed that CdCl2 significantly (P < 0.05) decreased plasma total protein (TP), albumin (A), blood hemoglobin (Hb), total erythrocytic count (TEC) and packed cell volume (PCV), while total leukocyte count (TLC) increased. Treatment with CdCl2 caused a significant (P < 0.05) decrease in sperm concentration, motility (%), weight of testes and epididymis, and increase in dead and abnormal sperm. Results demonstrated the beneficial influences of vitamin E, -carotene alone and/or in combination in reducing the harmful effects of CdCl2.

Research paper thumbnail of Antioxidant activities and lipid lowering effects of isoflavone in male rabbits

Food and Chemical Toxicology, 2004

Research paper thumbnail of The protective effect of Coriandrum sativum L . oil against liver toxicity induced by Ibuprofen in rats

Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and... more Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and in inflammation.Coriandrum sativum is cultivated for its aromatic and medicinal uses. The present study aims to evaluatethe protective effect of Coriandrum sativum volatile oil on hepatotoxicityof IBU in rats. Five groups of albino rats were used.Group l(control),groupll (C.sativum oil,40 mg/kg B.W. for 14 day), group lll (IBU group,100mg/kg bodyweight B.W., for 14 day), group lV (IBU+ C.sativum oil) and groupV (recovery group).The activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in the liver of different groups addition to the histological examination of the sections of liver. The results showed that IBU caused a significant decrease in the activity of ALT and AST in the liver. The histological examination of the liver showed many pathological changes. Administration of coriander volatile oilin the combination with IBU was able to significan...

Research paper thumbnail of The protective effect of Coriandrum sativum L. oil against liver toxicity induced by Ibuprofen in rats

Journal of Bioscience and Applied Research

Research paper thumbnail of Antibacterial Activity of Plants Essential Oils Against Some Epidemiologically Relevant Food-Borne Pathogens

The Open Public Health Journal, 2015

Research paper thumbnail of Oxidative stress modulation by R osmarinus officinalis in creosote-induced hepatotoxicity

Environmental Toxicology, 2014

Research paper thumbnail of Cross Sectional Study of Skin Carriage and Enterotoxigenicity of Staphylococcus aureus among Food Handlers

Open Journal of Medical Microbiology, 2014

Research paper thumbnail of Adsorption mechanisms of nicotine on humic acid and clay humic acid complex

Zeitschrift für Pflanzenernährung und Bodenkunde, 1990

Page 1. 33 Adsorption mechanisms of nicotine on humic acid and clay humic acid complex Ahmed H. K... more Page 1. 33 Adsorption mechanisms of nicotine on humic acid and clay humic acid complex Ahmed H. Khairy, Hoda H. Baghdadi and Elham A. Ghabbour Institute of Graduate Studies and Research, Alexandria University, PO Box 832, El-Shatby, Alexandria, Egypt ...

Research paper thumbnail of Comparison between biological and chemical treatment of wastewater containing nitrogen and phosphorus

Journal of Industrial Microbiology & Biotechnology, 2005

Research paper thumbnail of Effect of Isoflavones on Reproductive Performance, Testosterone Levels, Lipid Peroxidation, and Seminal Plasma Biochemistry of Male Rabbits

Journal of Environmental Science and Health, Part B- Pesticides, Food Contaminants, and Agricultural Wastes, 2004

The objective of this study was to determine the effect of either 2.5 mg/kg Body Weight or 5 mg/k... more The objective of this study was to determine the effect of either 2.5 mg/kg Body Weight or 5 mg/kg Body Weight (BW) doses of isoflavones on semen quality, testosterone levels, lipid peroxidation and semen biochemistry of male New Zealand White rabbits. Animals were given both 2.5 mg/kg BW and 5 mg/kg BW doses of isoflavones. The tested doses were given to rabbits orally every other day for 13 weeks. Treatment with isoflavones caused an increase (p < 0.05) in libido (by decreasing the reaction time), sperm concentration, sperm motility (%), total motile sperm per ejaculate (TMS), packed sperm volume (PSV), total functional sperm fraction (TFSF), total sperm output, initial fructose concentration and normal sperm, while dead sperm was reduced compared to control animals. On the other hand, ejaculate volume, initial hydrogen ion concentration (pH) and plasma testosterone levels did not change in treated animals with both doses of isoflavones as compared to control. Concentrations of thiobarbituric acid-reactive substances (TBARS), total lipids, and low density lipoprotein were significantly (p < 0.05) reduced in seminal plasma of rabbits treated with either 2.5 mg/kg BW or 5 mg/kg BW doses of isoflavones. While, the activities of glutathione S-transferase (GST), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alanine aminotransferase (ALT), acid phosphatase (AcP), and alkaline phosphatase (AlP) were significantly (p < 0.05) increased in seminal plasma of treated animals. Also, total cholesterol, percentage cholesterol (out of total lipids), and high density lipoprotein were significantly (p < 0.05) increased, while triglyceride did not change in seminal plasma of treated animals. Supplementation at either level of isoflavones did not cause changes in live body weight (LBW), dry matter intake (DMI), and relative weights of testes and epididymis. The present results showed that either 2.5 mg/kg BW or 5 mg/kg BW doses of isoflavones caused an improvement of some semen characteristics and did not have negative effects on male fertility.

Research paper thumbnail of Role of α-Tocopherol and β-Carotene in Ameliorating the Fenvalerate-Induced Changes in Oxidative Stress, Hemato-Biochemical Parameters, and Semen Quality of Male Rats

Journal of Environmental Science and Health, Part B, 2004

Abstract Role of α-tocopherol (vitamin E), β-carotene and/or their combination as antioxidants ag... more Abstract Role of α-tocopherol (vitamin E), β-carotene and/or their combination as antioxidants against the toxicity of fenvalerate on blood hematology, free radicals, biochemical parameters, and semen quality were studied in male rats. Fenvalerate (20 mg ...

Research paper thumbnail of Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and β-carotene

Food and Chemical Toxicology, 2004

Cadmium is a well-known human carcinogen and a potent nephrotoxin. Lipid peroxidation is involved... more Cadmium is a well-known human carcinogen and a potent nephrotoxin. Lipid peroxidation is involved in cadmium-related toxicity. Vitamin E and beta-carotene are effective antioxidants and free radical scavengers. Therefore, the present study was carried out to investigate the potential protective effects of vitamin E and beta-carotene alone or in combination against cadmium (Cd) toxicity. Cadmium chloride (CdCl2, 5 mg/kg BW, 1/15 LD50), vitamin E (100 mg/kg BW), beta-carotene (10 mg/kg BW), and vitamin E with beta-carotene (100 + 10 mg/kg BW, respectively) were orally administered by gavage alone or in combination. The tested doses were given to rats every other day (15 times). Results obtained showed that CdCl2 significantly (P < 0.05) induced free radicals in plasma, liver and brain. The activities of glutathione S-transferase (GST) (plasma and liver), alkaline phosphatase (AlP) (plasma and liver), aspartate aminotransferase (AST), alanine aminotransferase (ALT) (liver) and acetylcholinesterase (AChE) (plasma and brain) were significantly (P < 0.05) decreased due to CdCl2 administration, whereas, the activities of AST and ALT were increased in plasma. Treatment with CdCl2 caused a significant (P < 0.05) increase in glucose, urea, creatinine and bilirubin in plasma. On the other hand, results showed that CdCl2 significantly (P < 0.05) decreased plasma total protein (TP), albumin (A), blood hemoglobin (Hb), total erythrocytic count (TEC) and packed cell volume (PCV), while total leukocyte count (TLC) increased. Treatment with CdCl2 caused a significant (P < 0.05) decrease in sperm concentration, motility (%), weight of testes and epididymis, and increase in dead and abnormal sperm. Results demonstrated the beneficial influences of vitamin E, -carotene alone and/or in combination in reducing the harmful effects of CdCl2.

Research paper thumbnail of Antioxidant activities and lipid lowering effects of isoflavone in male rabbits

Food and Chemical Toxicology, 2004