Takuya Honda - Academia.edu (original) (raw)

Papers by Takuya Honda

International Journal of Sport and Health Science, 2008

This study aimed to investigate how long-term biweekly participation in health education classes ... more This study aimed to investigate how long-term biweekly participation in health education classes has affected the maintenance of independent lifestyle, care needs, and 10-year (125-month) mortality rates in Yoshida Village, where individuals among the community residents aged 58 years or older, participate in health education classes (Silver College). There were 1,013 people in total (male; n=456, 65.5±5.6y. and female; n=557, 71.5±9.5y.) on baseline in 1994. We examined participant gender, birth date and care needs in October 2004, degree of care needs, the fi rst date when care needs became grade 2 or higher, the status of participation in Silver College, and date of death. Kaplan-Meier survival analysis revealed that the survival rates of the participants and non-participants at the end of the trial were 90% and 67%, respectively. Cox's proportional hazards regression model showed that adjusted hazard ratios for age were 1.125 (95% CI: 1.111-1.139) in all subjects, 1.115 (95% CI: 1.095-1.136) in males, and 1.138 (95% CI: 1.117-1.158) in females. Adjusted hazard ratios for participation in health education classes were 0.270 (95% CI: 0.172-0.423) in all subjects, 0.423 (95% CI: 0.228-0.787) in males, and 0.215 (95% CI: 0.112-0.412) in females. Long-term comprehensive health education classes for middle-aged to elderly people including lifestyle, exercise, diet, and hot spa bathing, even if conducted biweekly, may be effective in the prevention of long-term care needs.

Journal of Epidemiology, 2010

Background: The objective of this review was to summarize findings on aquatic exercise and balneo... more Background: The objective of this review was to summarize findings on aquatic exercise and balneotherapy and to assess the quality of systematic reviews based on randomized controlled trials. Methods: Studies were eligible if they were systematic reviews based on randomized clinical trials (with or without a meta-analysis) that included at least 1 treatment group that received aquatic exercise or balneotherapy. We searched the following databases: Cochrane Database Systematic Review, MEDLINE, CINAHL, Web of Science, JDream II, and Ichushi-Web for articles published from the year 1990 to August 17, 2008. Results: We found evidence that aquatic exercise had small but statistically significant effects on pain relief and related outcome measures of locomotor diseases (eg, arthritis, rheumatoid diseases, and low back pain). However, long-term effectiveness was unclear. Because evidence was lacking due to the poor methodological quality of balneotherapy studies, we were unable to make any conclusions on the effects of intervention. There were frequent flaws regarding the description of excluded RCTs and the assessment of publication bias in several trials. Two of the present authors independently assessed the quality of articles using the AMSTAR checklist. Conclusions: Aquatic exercise had a small but statistically significant short-term effect on locomotor diseases. However, the effectiveness of balneotherapy in curing disease or improving health remains unclear.

Patient Preference and Adherence, 2014

The objective of this review was to summarize evidence for the effectiveness of music therapy (MT... more The objective of this review was to summarize evidence for the effectiveness of music therapy (MT) and to assess the quality of systematic reviews (SRs) based on randomized controlled trials (RCTs). Study design: An SR of SRs based on RCTs. Methods: Studies were eligible if they were RCTs. Studies included were those with at least one treatment group in which MT was applied. We searched the following databases from 1995 to October 1, 2012: MEDLINE via PubMed, CINAHL (Cumulative Index of Nursing and Allied Health Literature), Web of Science, Global Health Library, and Ichushi-Web. We also searched all Cochrane Database and Campbell Systematic Reviews up to October 1, 2012. Based on the International Classification of Diseases, 10th revision, we identified a disease targeted for each article. Results: Twenty-one studies met all inclusion criteria. This study included 16 Cochrane reviews. As a whole, the quality of the articles was very good. Eight studies were about "Mental and behavioural disorders (F00-99)"; there were two studies on "Diseases of the nervous system (G00-99)" and "Diseases of the respiratory system (J00-99)"; and there was one study each for "Endocrine, nutritional and metabolic diseases (E00-90)", "Diseases of the circulatory system (I00-99)", and "Pregnancy, childbirth and the puerperium (O60)". MT treatment improved the following: global and social functioning in schizophrenia and/or serious mental disorders, gait and related activities in Parkinson's disease, depressive symptoms, and sleep quality. Conclusion: This comprehensive summary of SRs demonstrated that MT treatment improved the following: global and social functioning in schizophrenia and/or serious mental disorders, gait and related activities in Parkinson's disease, depressive symptoms, and sleep quality. MT may have the potential for improving other diseases, but there is not enough evidence at present. Most importantly, no specific adverse effect or harmful phenomenon occurred in any of the studies, and MT was well tolerated by almost all patients.

Open Access Journal of Sports Medicine, 2012

Background: The purpose of this study was to report on the health benefits and curative effects o... more Background: The purpose of this study was to report on the health benefits and curative effects of aquatic exercise. Methods: We adopted the results of high-grade study designs (ie, randomized controlled trials and nonrandomized controlled trials), for which there were many studies on aquatic exercise. Aquatic exercise, in this study, means walking in all directions, stretching, and various exercises and conditioning performed with the feet grounded on the floor of a swimming pool. We excluded swimming. We decided to treat aquatic exercise, underwater exercise, hydrotherapy, and pool exercise as all having the same meaning. Results: Aquatic exercise had significant effects on pain relief and related outcome measurements for locomotor diseases. Conclusion: Patients may become more active, and improve their quality of life, as a result of aquatic exercise.

International Journal of General Medicine, 2011

Background: The objectives of this review were to integrate the evidence of curative effects thro... more Background: The objectives of this review were to integrate the evidence of curative effects through aquatic exercise and assess the quality of studies based on a review of nonrandomized controlled trials (nRCTs). Methods: Study design was a systematic review of nonrandomized controlled trials. Trials were eligible if they were nonrandomized clinical trials. Studies included one treatment group in which aquatic exercise was applied. We searched the following databases from 2000 up to July 20, 2009: MEDLINE via PubMed, CINAHL, and Ichushi-Web. Results: Twenty-one trials met all inclusion criteria. Languages included were English (N = 9), Japanese (N = 11), and Korean (N = 1). Target diseases were knee and/or hip osteoarthritis, poliomyelitis, chronic kidney disease, discomforts of pregnancy, cardiovascular diseases, and rotator cuff tears. Many studies on nonspecific disease (healthy participants) were included. All studies reported significant effectiveness in at least one or more outcomes. However results of evaluations with the TREND and CLEAR-NPT checklists generally showed a remarkable lack of description in the studies. Furthermore, there was the problem of heterogeneity, and we were therefore not able to perform a meta-analysis. Conclusion: Because there was insufficient evidence on aquatic exercise due to poor methodological and reporting quality and heterogeneity of nRCTs, we were unable to offer any conclusions about the effects of this intervention. However, we were able to identify problems with current nRCTs of aquatic exercise, and propose a strategy of strengthening study quality, stressing the importance of study feasibility as a future research agenda objective.

Frontiers in Psychology, 2013

While performing an action, the timing of when the sensory feedback is given can be used to estab... more While performing an action, the timing of when the sensory feedback is given can be used to establish the causal link between the action and its consequence. It has been shown that delaying the visual feedback while carrying an object makes people feel the mass of the object to be greater, suggesting that the feedback timing can also impact the perceived quality of an external object. In this study, we investigated the origin of the feedback timing information that influences the mass perception of the external object. Participants made a straight reaching movement while holding a manipulandum. The movement of the manipulandum was presented as a cursor movement on a monitor. In Experiment 1, various delays were imposed between the actual trajectory and the cursor movement. The participants' perceived mass of the manipulandum significantly increased as the delay increased to 400 ms, but this gain did not reach significance when the delay was 800 ms. This suggests the existence of a temporal tuning mechanism for incorporating the visual feedback into the perception of mass. In Experiment 2, we examined whether the increased mass perception during the visual delay was due to the prediction error of the visual consequence of an action or to the actual delay of the feedback itself. After the participants adapted to the feedback delay, the perceived mass of the object became lighter than before, indicating that updating the temporal prediction model for the visual consequence diminishes the overestimation of the object's mass. We propose that the misattribution of the visual delay into mass perception is induced by the sensorimotor prediction error, possibly when the amount of delay (error) is within the range that can reasonably include the consequence of an action.

Computational theory of motor control suggests that the brain continuously monitors motor command... more Computational theory of motor control suggests that the brain continuously monitors motor commands, to predict their sensory consequences before actual sensory feedback becomes available. Such prediction error is a driving force of motor learning, and therefore appropriate associations between motor commands and delayed sensory feedback signals are crucial. Indeed, artificially introduced delays in visual feedback have been reported to degrade motor learning. However, considering our perceptual ability to causally bind our own actions with sensory feedback, demonstrated by the decrease in the perceived time delay following repeated exposure to an artificial delay, we hypothesized that such perceptual binding might alleviate deficits of motor learning associated with delayed visual feedback. Here, we evaluated this hypothesis by investigating the ability of human participants to adapt their reaching movements in response to a novel visuomotor environment with 3 visual feedback conditions-no-delay, sudden-delay, and adapted-delay. To introduce novelty into the trials, the cursor position, which originally indicated the hand position in baseline trials, was rotated around the starting position. In contrast to the no-delay condition, a 200-ms delay was artificially introduced between the cursor and hand positions during the presence of visual rotation (sudden-delay condition), or before the application of visual rotation (adapted-delay condition). We compared the learning rate (representing how the movement error modifies the movement direction in the subsequent trial) between the 3 conditions. In comparison with the no-delay condition, the learning rate was significantly degraded for the sudden-delay condition. However, this degradation was significantly alleviated by prior exposure to the delay (adapted-delay condition). Our data indicate the importance of appropriate temporal associations between motor commands and sensory feedback in visuomotor learning. Moreover, they suggest that the brain is able to account for such temporal associations in a flexible manner.

Journal of Epidemiology, 2009

Background: Physical activity is known to prevent obesity and metabolic syndrome in middle-aged a... more Background: Physical activity is known to prevent obesity and metabolic syndrome in middle-aged and elderly people; however, the effectiveness of a comprehensive health education program for male white-collar employees is uncertain. Methods: Forty-three men volunteered to participate in this study and were randomly assigned into 2 groups. The intervention group participated in a 2-hour program comprising comprehensive health education and hot spa bathing, offered once every 2 weeks, in addition to individualized programs once a week, for 24 weeks. The control group received only general health guidance. We compared their lifestyle characteristics and physical and mental health criteria at baseline, immediately after the intervention, and 1 year after the end of the intervention. Results: Rates of adherence to individualized programs were 60.0 ± 27.2% and 30.5 ± 29.6% at the end of the intervention and at 1 year after the end of the intervention, respectively. Significant (P < 0.05) interaction of criteria was observed for cluster of differentiation 4+ (CD4+) cells and the ratio of cluster of differentiation 4+ to 8+ (CD4/8) cells, which were used to represent the participants' immunological function. We divided the intervention group into 2 subgroups on the basis of their attendance. Among the resulting 3 groups, significant interaction of criteria was observed for CD4+ and CD4/8 cells. In addition, the high attendance group had the highest CD4+ count and CD4/8 ratio. Conclusions: Participants who attended classes and/or performed the supplementary individualized programs tended to maintain their immunological function and to experience a decrease in body fat percentage. However, few effects were noted in participants with poor adherence, even in the intervention group.

Neuroscience Research, 2011

well-learned motor skill, by identifying brain regions showing enhanced activity-coupling with th... more well-learned motor skill, by identifying brain regions showing enhanced activity-coupling with the primary motor cortex (M1) using functional magnetic resonance imaging. Seven normal volunteers were well-trained in advance until their motor performance of continuously rotating two balls with their right hands became stable. We prepared two experiments, in each of which they repeated an experimental run wherein they performed the cyclic rotation as many times as possible in 16 s, 16 times. In TES experiment, we applied the 60-s TES to the hand before each of the 5th-12th runs, while remainders were preceded by ineffective sham stimulation. We expected the performance improvement in the TES runs. In control experiment, the sham stimulation was always provided. The TES enabled the participants to perform the movements at higher cycle. Within brain regions active during execution of the task, only the sensorimotor territory of basal ganglia enhanced its activity-coupling with M1 in association with the performance improvement. This was observed even when the activities in these regions decreased. Neither the behavioral change nor enhanced activity-coupling were observed in the control. Facilitation of functional connectivity between brain regions seems to be required for upgrading of a well-learned motor skill, especially in the cortico-subcortical motor circuit that is crucial for its motor control.

Neuroscience Research, 2010

An important issue in motor learning (or adaptation) is to reveal how our brain acquires the erro... more An important issue in motor learning (or adaptation) is to reveal how our brain acquires the error information necessary to improve the task performance. The present study focuses on the effect (problem) of timing of the error feedback. It was reported that aftereffect of prism adaptation in manual reaching task was significantly reduced if the visual feedback of the endpoint was delayed more than 50 ms (Kitazawa et al. 1995). This suggests that error feedback is most effective when it was synchronized with the end of reaching movement. Here, we raise two questions to further elucidate the mechanism accepting error information. First, which is the decisive timing for error feedback, the end of body movement or the end of given task? Second, if the task end is essential, is any sensory cue required for knowing the timing? To answer these questions, we conducted a virtual shooting experiment where subjects adjusted his/her wrist movement to meet a target as accurately as possible. The timing of visual feedback of hit location was manipulated: synchronized with (±0 ms), delayed to (+250 ms and +500 ms), and ahead of (−250 ms) the actual hit timing. The time from throwing movement to target hit was also varied (250 ms or 500 ms) to examine the effect of the time from the movement end. When the error feedback was given either delayed or ahead, the amount of the aftereffect significantly diminished, irrelevant to the time from movement end. This means that the adaptation was most prominent when the error information was fed back at the task end (not at the movement end). The similar consequence was seen even when no sensory cue was given at the task end. These results suggest that our brain may predict the timing of task end and accepts error information synchronized with the predicted task end.

Complementary Therapies in Medicine, 2014

The objectives of this review were to summarize the evidence from randomized controlled trials (R... more The objectives of this review were to summarize the evidence from randomized controlled trials (RCTs) on the effects of animal-assisted therapy (AAT). Studies were eligible if they were RCTs. Studies included one treatment group in which AAT was applied. We searched the following databases from 1990 up to October 31, 2012: MEDLINE via PubMed, CINAHL, Web of Science, Ichushi Web, GHL, WPRIM, and PsycINFO. We also searched all Cochrane Database up to October 31, 2012. Eleven RCTs were identified, and seven studies were about ''Mental and behavioral disorders''. Types of animal intervention were dog, cat, dolphin, bird, cow, rabbit, ferret, and guinea pig. The RCTs conducted have been of relatively low quality. We could not perform meta-analysis because of heterogeneity. In a study environment limited to the people who like animals, AAT may be an effective treatment for mental and behavioral disorders such as depression, schizophrenia, and alcohol/drug addictions, and is based on a holistic approach through interaction with animals in nature. ଝ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

Frontiers in Psychology, 2012

Sensory prediction error, which is the difference between actual and predicted sensory consequenc... more Sensory prediction error, which is the difference between actual and predicted sensory consequences, is a driving force of motor learning. Thus, appropriate temporal associations between the actual sensory feedback signals and motor commands for predicting sensory consequences are crucial for the brain to calculate the sensory prediction error accurately. Indeed, it has been shown that artificially introduced delays in visual feedback degrade motor learning. However, our previous study has showed that degraded adaptation is alleviated by prior habituation to the delay. Here, we investigate how the motor learning system accomplishes this alleviation. After the subjects habituated reaching movements in either 0-or 200-ms delayed cursor, visual rotation of 10˚was imposed to the cursor with varying delay (0, 100, 200, or 300 ms) with each delay imposed in at least 1 out of 5-6 trials.Then, the aftereffect in the next trial was quantified to evaluate the adaptation response. After habituation to the 0-ms delayed cursor, the adaptation response was maximal when the visual feedback of the perturbation was provided with 0-ms delay and gradually decreased as the delay increased. On the other hand, habituation to the 200-ms delayed cursor alleviated the degraded adaptation response to the visual perturbation imposed during the 200-ms and longer delay (300 ms). However, habituation did not affect the adaptation response to the visual perturbation imposed during delays (0-and 100-ms delay) shorter than the habituated delay (200 ms). These results may be explained by assuming that habituation to the delayed feedback not only shifts the position of the hand predicted by motor command toward the delayed cursor positions, but also increases the degree to which the brain uses a certain amount of sensory prediction error to correct a motor command.