Karin Horvath - Academia.edu (original) (raw)
Papers by Karin Horvath
Romanian Journal of Ophtalmology, Dec 15, 2022
PubMed, 2004
Purpose: To evaluate the technical particularities of phacoemulsification and the intraoperative ... more Purpose: To evaluate the technical particularities of phacoemulsification and the intraoperative complications in posterior polar cataract. Material and methods: Prospective study which comprises 10 eyes with posterior polar cataract (8 patients), operated on between May 2001 and April 2004 in the ophthalmology department of the Military Hospital Cluj-Napoca, by the same surgeon. Phacoemulsification with low parameters was performed in all cases, and acrylic and PMMA intraocular lenses were implanted in 9 eyes. Results: The patients' age was between 24 and 80 years, with a mean age of 55.12 years. The majority of the patients presented bilateral posterior polar cataract (70%), but only 2 patients were operated on the both eyes in the analyzed period. The posterior capsule rupture occurred in 4 eyes (40%). A posterior residual plaque was attended in one case, but did not influence the short term visual acuity. The visual acuity of the 3 cases which were affected unilaterally was not influenced by the surgery, which was without complications in 2 cases. The causes were preexisting amblyopia. Conclusions: The study confirms the high risk to posterior capsule rupture during posterior cataract surgery and the high incidence of the bilateral form (70%).
Arquivos Brasileiros de Oftalmologia, 2016
![Research paper thumbnail of [Diagnostic and therapeutic problems in a case of non-Hodgkin lymphoma with ocular involvement]](https://attachments.academia-assets.com/119654722/thumbnails/1.jpg)
](PubMed, 2007
The majority of malignant non-Hodgkin lymphomas are located in lymph nodes, but there are other l... more The majority of malignant non-Hodgkin lymphomas are located in lymph nodes, but there are other localizations such as orbital, conjunctival, in the eyelids, or very rare intraocular. The aim of this case is to discuss the diagnostic and therapeutic problems in a case of LMNH with ophthalmologic extension.
Frontiers in Medicine
AimThe purpose of the study was to assess the efficacy of topographical and tomographical indices... more AimThe purpose of the study was to assess the efficacy of topographical and tomographical indices given by the Pentacam (pachymetric, tomopetric, and aberometric) in clinical and subclinical keratoconus (KCN) diagnosis.Material and MethodsIn this observational analytic retrospective study, patients with abnormal findings in topography and tomography maps but with no signs on clinical examination (subclinical KCN group, sKCN), patients with clinical keratoconus (KCN group), and healthy subjects (Control group) were evaluated.ResultsThe KCN group proved significantly different (p < 0.001) values of the investigated parameters than the Control group. Eleven out of 28 investigated parameters proved significantly different in the sKCN group compared to controls (p < 0.001). Two topographic measurements, namely I-S (cut-off = 1.435, a large value indicates the presence of KCN) and CCT (cut-off = 537, a small value indicates the presence of KCN), showed AUCs equal to 1 [0.999 to 1]. ...
Alfablocantele se utilizează în tratamentul simptomelor adenomului de prostată la bărbaţi, respec... more Alfablocantele se utilizează în tratamentul simptomelor adenomului de prostată la bărbaţi, respectiv ale retenţiei urinare la femei. Scopul studiului a fost de a determina tipul şi incidenţa efectelor adverse oculare din timpul facoemulsificării cataractei. Metodă: studiu prospectiv observaţional nonrandomizat ce include 259 ochi (257 pacienţi) operaţi de un chirurg, utilizându-se aceeaşi tehnică; nu s-au inclus în studiu cataractele complicate din traumatisme, uveite, glaucoame operate. Efecte adverse s-au semnalat la aproximativ 4%, toţi aceşti pacienţi urmând un tratament alfa1 blocant, unii dintre ei chiar pentru o perioadă foarte scurtă. Aceste efecte adverse alcătuiesc sindromul floppy iris (IFIS). Fenomenele iriene au fost bine controlate prin utilizarea adenalinei intracamerular. Într-un singur caz a fost nevoie de retractoare iriene. Nu s-au înregistrat complicaţii majore intraoperatorii. Toate cazurile de IFIS intraoperator s-au înregistrat la pacienţii cu tratament alfa1 blocant. Există măsuri intraoperatorii accesibile ce reduc semnificativ amploarea sindromului, scăzând astfel rata complicaţiilor.
Ocular surface disorder such as "dry eye" significantly affects subjective and objectiv... more Ocular surface disorder such as "dry eye" significantly affects subjective and objective postoperative results, especially in anterior segment surgeries. Preoperative recognition of ocular surface pathology, along with an eyelid-meibomian co-affection and appropriate preoperative preparation of the ocular surface remain essential conditions for successful surgery. It discusses the factors that determine the setting of ocular surface diseases, its pathophysiological mechanisms, diagnostic methods and therapeutic approaches. Cuvinte cheie: OSD, chirurgie oculară Rezumat: Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv, rezultatele postoperatorii în intervenţiile chirurgicale în special de pol anterior. Recunoaşterea preoperatorie a unei patologii de suprafaţă oculară, alături de o coafectare palpebrală-meibomiană, cu iniţierea unei pregătiri preoperatorii adecvate a suprafeţei oculare constituie o condiţie esenţială...
Laser pointer damage in children can occasionally be misdiagnosed as a macular dystrophy disease.... more Laser pointer damage in children can occasionally be misdiagnosed as a macular dystrophy disease. Our objective is to present the macular phenotypes associated with laser buns. We present the case of a 14-year-old boy with bilateral blurred vision, without known personal or family history, after deliberately staring into a laser beam. The fundus examination describes a hypopigmented round-shaped foveal lesion. The optical coherence topography showed a retinal pigment epithelial change in the both eyes. Loss of retinal function due to laser pointer injury has increased over the years, thus making the recognition of characteristic paramount.
Rezumat: Scopul lucrării: lucrarea se adresează unei patologii interdisciplinare, de etiologie si... more Rezumat: Scopul lucrării: lucrarea se adresează unei patologii interdisciplinare, de etiologie sinusală cu implicaţie orbitară, care ridică adesea probleme în ceea ce priveşte rezolvarea în timp util a cazurilor. Material şi metodă: se prezintă un lot de 8 copii cu vârste cuprinse între 3 şi 18 ani, cu diagnostice oftalmologice diverse (celulită orbitară, flegmon, dacriocistită, nevrită optică retrobulbară), dar care prezentau cu toţii sinuzite paranazale grave. Se descrie managementul cazurilor, respectiv cel mai eficient tratament. Rezultate: datorită manifestării în primul rând oftalmologice a bolii, copiii se prezintă de regulă la oftalmolog, acesta fiind cel care iniţiază o strategie investigaţională, precum şi un tratament de debut. Odată cu diagnosticarea radioimagistică a unei sinuzite paranazale, cel mai frecvent etmoidale în cazul copiilor, s-a luat în considerare drenajul focarului de infecţie sinusal de către specialistul ORL. Toate intervenţiile s-au efectuat prin metoda FESS, cu rezultate excelente. Concluzii: fiind vorba de multe ori de urgenţe majore, cu pericol vital la copil, oftalmologul trebuie să fie în măsură să stabilească în timp util un diagnostic de probabilitate orientând copilul către consulturile paraclinice, interclinice (CT, ORL) competente în rezolvarea cazului.
Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv... more Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv, rezultatele postoperatorii în intervenţiile chirurgicale în special de pol anterior. Recunoaşterea preoperatorie a unei patologii de suprafaţă oculară, alături de o coafectare palpebralămeibomiană, cu iniţierea unei pregătiri preoperatorii adecvate a suprafeţei oculare constituie o condiţie esenţială a reuşitei chirurgicale. Se discută factorii ce determină instalarea unei patologii de suprafaţă oculară, mecanismele sale fiziopatologice, metodele de diagnostic precum şi abordările terapeutice.
One of the most commonly used modern terms for the generic evaluation of human existence is the q... more One of the most commonly used modern terms for the generic evaluation of human existence is the quality of life. According to the definition of the World Health Organization, this is the individuals’ perception of their own social status, in the context of the social value systems they adhere to, while also being co-dependent on their own necessities, standards and aspirations. This complex approach entails, besides the perception of their own body, the understanding of the surrounding environment in which we live our lives. Their utility consists in assuring the best possible correlation and adaptation between these two benchmarks. The acknowledgement of these indispensable components is mainly accomplished through the sensory organs. The majority of the classic sensory organs and some of the ones that were later correlated with man’s capacity of modern integration into his ecosystem belong to the field of ENT. Thus, it is only natural that, besides the aesthetic concern...
Recently, advanced technology of cataract surgery entails high expectations from the patients. Th... more Recently, advanced technology of cataract surgery entails high expectations from the patients. The appearance of Premium intraocular lenses, due to their exceptional qualities, involves a perfect surgery. They are implanted only on the recommendation of an experienced ophthalmologist and after careful preoperative counselling of patients. Cuvinte cheie: cataractă, chirurgie refractivă, cristaline artificiale Premium, presbiopie Rezumat: In ultima perioadă, tehnologia avansată a operaţiei de cataractă atrage după sine asteptări crescute din partea pacienţilor. Apariţia cristalinelor artificiale Premium, datorită calităţilor excepţionale pe care acestea le au, implică realizarea unei operaţii perfecte din punct de vedere chirurgical. Aceste tipuri de lentile se implanteaz ă numai la recomandarea unui oftalmolog cu experienţă, obligatorie fiind o atentă consiliere preoperatorie a pacienţilor.
Romanian journal of ophthalmology, 2015
Retinal vein occlusion (RVO) is the second most common retinal vein disease with significant visu... more Retinal vein occlusion (RVO) is the second most common retinal vein disease with significant visual loss via thrombus or compression of vein wall. Thrombophilia is the predisposition to vascular thrombosis with the existence of genetic defect that leads to blood hypercoagulability. This report describes the case of a 55 year old male patient, with an active life who presented himself at the emergency room with acute visual lose, insidious and progressive visual field constriction, without any known history of neurological or vascular diseases. The examinations revealed unilateral optic nerve head edema, the fluorescein angiography was specific for nonischemic central retinal vein occlusion CRVO complicated with macular edema. Blood examinations has emphasized the presence of the heterozygous mutation A1298C in the methylenetetrahydrofolate reductase gene (MTHFR), the only one presented from the thrombophilia screen panel and a slightly elevated cholesterol level. During the follow-u...
Acta Marisiensis - Seria Medica, 2020
Objective: The aim of our study was to evaluate whether blood serum zinc concentration correlates... more Objective: The aim of our study was to evaluate whether blood serum zinc concentration correlates with the thickness of human retina layers, in hypertensive patients with microvascular damage. Methods: Retinas of elderly patients with arterial hypertension and microvascular damage were imaged using a swept-source ocular coherence tomography from Topcon. Automatic retinal segmentation was applied on a 6mm X 6mm scan protocol and average thickness for 5 examined layers was used for statistical analysis. Serum zinc concentration was measured using the Zinc Assay kit from Sentinel Diagnostics in a spectrophotometric method. Results: The average age of the twenty-three enrolled patients was 70 years, varying between 62 and 76. The mean zinc value was 9.9 µmol/l ±1.62 (SD). All five examined layers of the retina presented inverse correlation with serum zinc concentration. The complex including the inner plexiform layer and ganglion cell layer indicated the Spearman’s (rho) correlation coe...
Therapeutics and Clinical Risk Management, 2021
The purpose of the present study was to assess the long-term efficiency and safety of the "epi-of... more The purpose of the present study was to assess the long-term efficiency and safety of the "epi-off" accelerated CXL (9 mW/cm 2 for 10 minutes) in comparison to the standard "epi-off" CXL (3 mW/cm 2 for 30 minutes) in terms of topographical and keratometric parameters, refractive data and visual outcomes at 7 years of follow-up, in progressive keratoconus. Material and Method: A retrospective and comparative study was performed. A total of 183 eyes from 183 patients with documented progressive keratoconus were included in the study. The patients were divided in two groups: 93 eyes from 93 patients underwent "epi-off" standard cross-linking technique (3 mW/cm 2 for 30 minutes) (S-CXL group) and 90 eyes from 90 patients underwent accelerated "epi-off" corneal CXL technique (9 mW/cm 2 for 10 minutes) (A-CXL group). Results: Improvements in uncorrected distance visual acuity (UDVA) were statistically significant compared to baseline values in both groups at each time-point visit (p=0.0421 at 1 year, p=0.0411 at 7 years for A-CXL and p=0.0375 at 1 year, p=0.0389 at 7 years for S-CXL). At 7 years there was a statistically significant increase in CDVA (p=0.039 in the A-CXL group and p=0.0343 in the S-CXL group at 7 years). Statistically significant reduction was noticed in Ksteep (p=0.0411 in A-CXL group and p=0.0224 in S-CXL group), Kflat (p=0.0198 in A-CXL group and p=0.008 in S-CXL group), K mean (p=0.0106 in A-CXL group and p=0.0193 in S-CXL group) and Kmax (p=0.0413 in A-CXL group and p=0.054 in S-CXL group) at 7 years, compared to baseline values, in both groups, but without any statistically difference between the two procedures, at all time-point visits (p>0.05). Conclusion: The long-term outcomes of "epi-off" accelerated corneal collagen crosslinking-UVA (9 mW/cm 2 for 10 minutes) are similar to standard "epi-off" corneal collagen crosslinking procedure in the treatment of progressive keratoconus.
Materiale Plastice, 2018
The developments in the biocompatible materials and additive manufacturing technologies gave birt... more The developments in the biocompatible materials and additive manufacturing technologies gave birth to new possibilities in reconstructive surgery. In addition to revolutionizing the diagnostic possibilities, the modern medical imaging has led to the development of surgical planning software. Using these state-of-the-art technologies, a new standard of care is rising with the spread of patient specific implants. Our view in studying and using these materials and technologies goes beyond their biocompatibility, focusing on the functional and esthetic impact of these restorations. Our aim is to show their potential benefits and pitfalls presenting a couple of posttraumatic and oncological application possibilities, focusing on the new presurgical planning, choice of materials and manufacturing technologies.
Journal of Interdisciplinary Medicine, 2018
Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract... more Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract surgery. This unwanted photic phenomenon has gained ground and is a major postoperative concern. Visual acuity is not sufficient in evaluating the postoperative visual function. The aim of this study was to determine the efficacy of using a preexistent questionnaire in determining the presence of dysphotopsia. Material and method: We conducted a prospective study, using the modified Visual Function Index (VF-14) and the Ocular Surface Disease Index (OSDI) surveys, completed on patients that underwent uncomplicated phacoemulsification with intraocular lens implantation between November 2016 and November 2017. Patients included in the study had no known ocular comorbidities and had no other possible postoperative explanation for these visual phenomena. Three weeks after the surgery, the questionnaire was filled up by one individual examiner. Results: Of the 50 patients considered, 37 pati...
Journal of Interdisciplinary Medicine, 2018
Background: Lacrimal drainage system lymphomas are rare, accounting for less than 10% of lacrimal... more Background: Lacrimal drainage system lymphomas are rare, accounting for less than 10% of lacrimal sac tumors. They often appear as a secondary involvement within the confines of systemic lymphoproliferative disorders, therefore detailed ophthalmological examination and auxiliary testing is necessary to have an accurate diagnosis. Case report: We present the case of a 72-year-old woman with a medical history of chronic lymphocytic leukemia and small lymphocytic lymphoma. She presented to the ophthalmology clinic with a painful, discharging swelling in the right lacrimal sac area. Magnetic resonance imaging revealed a mass in the right nasolacrimal duct. A right external dacryocystorhinostomy was performed. The histological findings led to a diagnosis of small lymphocytic lymphoma. Conclusions: Special attention is required in cases of known systemic hematological disorders that associate with nasolacrimal duct obstruction or epiphora. Quick recognition and a full history with multidi...
ORL.ro, 2019
One of the most commonly used modern terms for the generic evaluation of human existence is the q... more One of the most commonly used modern terms for the generic evaluation of human existence is the quality of life. According to the definition of the World Health Organization, this is the individuals’ perception of their own social status, in the context of the social value systems they adhere to, while also being co-dependent on their own necessities, standards and aspirations. This complex approach entails, besides the perception of their own body, the understanding of the surrounding environment in which we live our lives. Their utility consists in assuring the best possible correlation and adaptation between these two benchmarks. The acknowledgement of these indispensable components is mainly accomplished through the sensory organs. The majority of the classic sensory organs and some of the ones that were later correlated with man’s capacity of modern integration into his ecosystem belong to the field of ENT. Thus, it is only natural that, besides the aesthetic concern...
Romanian Journal of Ophtalmology, Dec 15, 2022
PubMed, 2004
Purpose: To evaluate the technical particularities of phacoemulsification and the intraoperative ... more Purpose: To evaluate the technical particularities of phacoemulsification and the intraoperative complications in posterior polar cataract. Material and methods: Prospective study which comprises 10 eyes with posterior polar cataract (8 patients), operated on between May 2001 and April 2004 in the ophthalmology department of the Military Hospital Cluj-Napoca, by the same surgeon. Phacoemulsification with low parameters was performed in all cases, and acrylic and PMMA intraocular lenses were implanted in 9 eyes. Results: The patients' age was between 24 and 80 years, with a mean age of 55.12 years. The majority of the patients presented bilateral posterior polar cataract (70%), but only 2 patients were operated on the both eyes in the analyzed period. The posterior capsule rupture occurred in 4 eyes (40%). A posterior residual plaque was attended in one case, but did not influence the short term visual acuity. The visual acuity of the 3 cases which were affected unilaterally was not influenced by the surgery, which was without complications in 2 cases. The causes were preexisting amblyopia. Conclusions: The study confirms the high risk to posterior capsule rupture during posterior cataract surgery and the high incidence of the bilateral form (70%).
Arquivos Brasileiros de Oftalmologia, 2016
PubMed, 2007
The majority of malignant non-Hodgkin lymphomas are located in lymph nodes, but there are other l... more The majority of malignant non-Hodgkin lymphomas are located in lymph nodes, but there are other localizations such as orbital, conjunctival, in the eyelids, or very rare intraocular. The aim of this case is to discuss the diagnostic and therapeutic problems in a case of LMNH with ophthalmologic extension.
Frontiers in Medicine
AimThe purpose of the study was to assess the efficacy of topographical and tomographical indices... more AimThe purpose of the study was to assess the efficacy of topographical and tomographical indices given by the Pentacam (pachymetric, tomopetric, and aberometric) in clinical and subclinical keratoconus (KCN) diagnosis.Material and MethodsIn this observational analytic retrospective study, patients with abnormal findings in topography and tomography maps but with no signs on clinical examination (subclinical KCN group, sKCN), patients with clinical keratoconus (KCN group), and healthy subjects (Control group) were evaluated.ResultsThe KCN group proved significantly different (p < 0.001) values of the investigated parameters than the Control group. Eleven out of 28 investigated parameters proved significantly different in the sKCN group compared to controls (p < 0.001). Two topographic measurements, namely I-S (cut-off = 1.435, a large value indicates the presence of KCN) and CCT (cut-off = 537, a small value indicates the presence of KCN), showed AUCs equal to 1 [0.999 to 1]. ...
Alfablocantele se utilizează în tratamentul simptomelor adenomului de prostată la bărbaţi, respec... more Alfablocantele se utilizează în tratamentul simptomelor adenomului de prostată la bărbaţi, respectiv ale retenţiei urinare la femei. Scopul studiului a fost de a determina tipul şi incidenţa efectelor adverse oculare din timpul facoemulsificării cataractei. Metodă: studiu prospectiv observaţional nonrandomizat ce include 259 ochi (257 pacienţi) operaţi de un chirurg, utilizându-se aceeaşi tehnică; nu s-au inclus în studiu cataractele complicate din traumatisme, uveite, glaucoame operate. Efecte adverse s-au semnalat la aproximativ 4%, toţi aceşti pacienţi urmând un tratament alfa1 blocant, unii dintre ei chiar pentru o perioadă foarte scurtă. Aceste efecte adverse alcătuiesc sindromul floppy iris (IFIS). Fenomenele iriene au fost bine controlate prin utilizarea adenalinei intracamerular. Într-un singur caz a fost nevoie de retractoare iriene. Nu s-au înregistrat complicaţii majore intraoperatorii. Toate cazurile de IFIS intraoperator s-au înregistrat la pacienţii cu tratament alfa1 blocant. Există măsuri intraoperatorii accesibile ce reduc semnificativ amploarea sindromului, scăzând astfel rata complicaţiilor.
Ocular surface disorder such as "dry eye" significantly affects subjective and objectiv... more Ocular surface disorder such as "dry eye" significantly affects subjective and objective postoperative results, especially in anterior segment surgeries. Preoperative recognition of ocular surface pathology, along with an eyelid-meibomian co-affection and appropriate preoperative preparation of the ocular surface remain essential conditions for successful surgery. It discusses the factors that determine the setting of ocular surface diseases, its pathophysiological mechanisms, diagnostic methods and therapeutic approaches. Cuvinte cheie: OSD, chirurgie oculară Rezumat: Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv, rezultatele postoperatorii în intervenţiile chirurgicale în special de pol anterior. Recunoaşterea preoperatorie a unei patologii de suprafaţă oculară, alături de o coafectare palpebrală-meibomiană, cu iniţierea unei pregătiri preoperatorii adecvate a suprafeţei oculare constituie o condiţie esenţială...
Laser pointer damage in children can occasionally be misdiagnosed as a macular dystrophy disease.... more Laser pointer damage in children can occasionally be misdiagnosed as a macular dystrophy disease. Our objective is to present the macular phenotypes associated with laser buns. We present the case of a 14-year-old boy with bilateral blurred vision, without known personal or family history, after deliberately staring into a laser beam. The fundus examination describes a hypopigmented round-shaped foveal lesion. The optical coherence topography showed a retinal pigment epithelial change in the both eyes. Loss of retinal function due to laser pointer injury has increased over the years, thus making the recognition of characteristic paramount.
Rezumat: Scopul lucrării: lucrarea se adresează unei patologii interdisciplinare, de etiologie si... more Rezumat: Scopul lucrării: lucrarea se adresează unei patologii interdisciplinare, de etiologie sinusală cu implicaţie orbitară, care ridică adesea probleme în ceea ce priveşte rezolvarea în timp util a cazurilor. Material şi metodă: se prezintă un lot de 8 copii cu vârste cuprinse între 3 şi 18 ani, cu diagnostice oftalmologice diverse (celulită orbitară, flegmon, dacriocistită, nevrită optică retrobulbară), dar care prezentau cu toţii sinuzite paranazale grave. Se descrie managementul cazurilor, respectiv cel mai eficient tratament. Rezultate: datorită manifestării în primul rând oftalmologice a bolii, copiii se prezintă de regulă la oftalmolog, acesta fiind cel care iniţiază o strategie investigaţională, precum şi un tratament de debut. Odată cu diagnosticarea radioimagistică a unei sinuzite paranazale, cel mai frecvent etmoidale în cazul copiilor, s-a luat în considerare drenajul focarului de infecţie sinusal de către specialistul ORL. Toate intervenţiile s-au efectuat prin metoda FESS, cu rezultate excelente. Concluzii: fiind vorba de multe ori de urgenţe majore, cu pericol vital la copil, oftalmologul trebuie să fie în măsură să stabilească în timp util un diagnostic de probabilitate orientând copilul către consulturile paraclinice, interclinice (CT, ORL) competente în rezolvarea cazului.
Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv... more Patologia suprafeţei oculare de tip "ochi uscat" influenţează semnificativ, obiectiv şi subiectiv, rezultatele postoperatorii în intervenţiile chirurgicale în special de pol anterior. Recunoaşterea preoperatorie a unei patologii de suprafaţă oculară, alături de o coafectare palpebralămeibomiană, cu iniţierea unei pregătiri preoperatorii adecvate a suprafeţei oculare constituie o condiţie esenţială a reuşitei chirurgicale. Se discută factorii ce determină instalarea unei patologii de suprafaţă oculară, mecanismele sale fiziopatologice, metodele de diagnostic precum şi abordările terapeutice.
One of the most commonly used modern terms for the generic evaluation of human existence is the q... more One of the most commonly used modern terms for the generic evaluation of human existence is the quality of life. According to the definition of the World Health Organization, this is the individuals’ perception of their own social status, in the context of the social value systems they adhere to, while also being co-dependent on their own necessities, standards and aspirations. This complex approach entails, besides the perception of their own body, the understanding of the surrounding environment in which we live our lives. Their utility consists in assuring the best possible correlation and adaptation between these two benchmarks. The acknowledgement of these indispensable components is mainly accomplished through the sensory organs. The majority of the classic sensory organs and some of the ones that were later correlated with man’s capacity of modern integration into his ecosystem belong to the field of ENT. Thus, it is only natural that, besides the aesthetic concern...
Recently, advanced technology of cataract surgery entails high expectations from the patients. Th... more Recently, advanced technology of cataract surgery entails high expectations from the patients. The appearance of Premium intraocular lenses, due to their exceptional qualities, involves a perfect surgery. They are implanted only on the recommendation of an experienced ophthalmologist and after careful preoperative counselling of patients. Cuvinte cheie: cataractă, chirurgie refractivă, cristaline artificiale Premium, presbiopie Rezumat: In ultima perioadă, tehnologia avansată a operaţiei de cataractă atrage după sine asteptări crescute din partea pacienţilor. Apariţia cristalinelor artificiale Premium, datorită calităţilor excepţionale pe care acestea le au, implică realizarea unei operaţii perfecte din punct de vedere chirurgical. Aceste tipuri de lentile se implanteaz ă numai la recomandarea unui oftalmolog cu experienţă, obligatorie fiind o atentă consiliere preoperatorie a pacienţilor.
Romanian journal of ophthalmology, 2015
Retinal vein occlusion (RVO) is the second most common retinal vein disease with significant visu... more Retinal vein occlusion (RVO) is the second most common retinal vein disease with significant visual loss via thrombus or compression of vein wall. Thrombophilia is the predisposition to vascular thrombosis with the existence of genetic defect that leads to blood hypercoagulability. This report describes the case of a 55 year old male patient, with an active life who presented himself at the emergency room with acute visual lose, insidious and progressive visual field constriction, without any known history of neurological or vascular diseases. The examinations revealed unilateral optic nerve head edema, the fluorescein angiography was specific for nonischemic central retinal vein occlusion CRVO complicated with macular edema. Blood examinations has emphasized the presence of the heterozygous mutation A1298C in the methylenetetrahydrofolate reductase gene (MTHFR), the only one presented from the thrombophilia screen panel and a slightly elevated cholesterol level. During the follow-u...
Acta Marisiensis - Seria Medica, 2020
Objective: The aim of our study was to evaluate whether blood serum zinc concentration correlates... more Objective: The aim of our study was to evaluate whether blood serum zinc concentration correlates with the thickness of human retina layers, in hypertensive patients with microvascular damage. Methods: Retinas of elderly patients with arterial hypertension and microvascular damage were imaged using a swept-source ocular coherence tomography from Topcon. Automatic retinal segmentation was applied on a 6mm X 6mm scan protocol and average thickness for 5 examined layers was used for statistical analysis. Serum zinc concentration was measured using the Zinc Assay kit from Sentinel Diagnostics in a spectrophotometric method. Results: The average age of the twenty-three enrolled patients was 70 years, varying between 62 and 76. The mean zinc value was 9.9 µmol/l ±1.62 (SD). All five examined layers of the retina presented inverse correlation with serum zinc concentration. The complex including the inner plexiform layer and ganglion cell layer indicated the Spearman’s (rho) correlation coe...
Therapeutics and Clinical Risk Management, 2021
The purpose of the present study was to assess the long-term efficiency and safety of the "epi-of... more The purpose of the present study was to assess the long-term efficiency and safety of the "epi-off" accelerated CXL (9 mW/cm 2 for 10 minutes) in comparison to the standard "epi-off" CXL (3 mW/cm 2 for 30 minutes) in terms of topographical and keratometric parameters, refractive data and visual outcomes at 7 years of follow-up, in progressive keratoconus. Material and Method: A retrospective and comparative study was performed. A total of 183 eyes from 183 patients with documented progressive keratoconus were included in the study. The patients were divided in two groups: 93 eyes from 93 patients underwent "epi-off" standard cross-linking technique (3 mW/cm 2 for 30 minutes) (S-CXL group) and 90 eyes from 90 patients underwent accelerated "epi-off" corneal CXL technique (9 mW/cm 2 for 10 minutes) (A-CXL group). Results: Improvements in uncorrected distance visual acuity (UDVA) were statistically significant compared to baseline values in both groups at each time-point visit (p=0.0421 at 1 year, p=0.0411 at 7 years for A-CXL and p=0.0375 at 1 year, p=0.0389 at 7 years for S-CXL). At 7 years there was a statistically significant increase in CDVA (p=0.039 in the A-CXL group and p=0.0343 in the S-CXL group at 7 years). Statistically significant reduction was noticed in Ksteep (p=0.0411 in A-CXL group and p=0.0224 in S-CXL group), Kflat (p=0.0198 in A-CXL group and p=0.008 in S-CXL group), K mean (p=0.0106 in A-CXL group and p=0.0193 in S-CXL group) and Kmax (p=0.0413 in A-CXL group and p=0.054 in S-CXL group) at 7 years, compared to baseline values, in both groups, but without any statistically difference between the two procedures, at all time-point visits (p>0.05). Conclusion: The long-term outcomes of "epi-off" accelerated corneal collagen crosslinking-UVA (9 mW/cm 2 for 10 minutes) are similar to standard "epi-off" corneal collagen crosslinking procedure in the treatment of progressive keratoconus.
Materiale Plastice, 2018
The developments in the biocompatible materials and additive manufacturing technologies gave birt... more The developments in the biocompatible materials and additive manufacturing technologies gave birth to new possibilities in reconstructive surgery. In addition to revolutionizing the diagnostic possibilities, the modern medical imaging has led to the development of surgical planning software. Using these state-of-the-art technologies, a new standard of care is rising with the spread of patient specific implants. Our view in studying and using these materials and technologies goes beyond their biocompatibility, focusing on the functional and esthetic impact of these restorations. Our aim is to show their potential benefits and pitfalls presenting a couple of posttraumatic and oncological application possibilities, focusing on the new presurgical planning, choice of materials and manufacturing technologies.
Journal of Interdisciplinary Medicine, 2018
Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract... more Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract surgery. This unwanted photic phenomenon has gained ground and is a major postoperative concern. Visual acuity is not sufficient in evaluating the postoperative visual function. The aim of this study was to determine the efficacy of using a preexistent questionnaire in determining the presence of dysphotopsia. Material and method: We conducted a prospective study, using the modified Visual Function Index (VF-14) and the Ocular Surface Disease Index (OSDI) surveys, completed on patients that underwent uncomplicated phacoemulsification with intraocular lens implantation between November 2016 and November 2017. Patients included in the study had no known ocular comorbidities and had no other possible postoperative explanation for these visual phenomena. Three weeks after the surgery, the questionnaire was filled up by one individual examiner. Results: Of the 50 patients considered, 37 pati...
Journal of Interdisciplinary Medicine, 2018
Background: Lacrimal drainage system lymphomas are rare, accounting for less than 10% of lacrimal... more Background: Lacrimal drainage system lymphomas are rare, accounting for less than 10% of lacrimal sac tumors. They often appear as a secondary involvement within the confines of systemic lymphoproliferative disorders, therefore detailed ophthalmological examination and auxiliary testing is necessary to have an accurate diagnosis. Case report: We present the case of a 72-year-old woman with a medical history of chronic lymphocytic leukemia and small lymphocytic lymphoma. She presented to the ophthalmology clinic with a painful, discharging swelling in the right lacrimal sac area. Magnetic resonance imaging revealed a mass in the right nasolacrimal duct. A right external dacryocystorhinostomy was performed. The histological findings led to a diagnosis of small lymphocytic lymphoma. Conclusions: Special attention is required in cases of known systemic hematological disorders that associate with nasolacrimal duct obstruction or epiphora. Quick recognition and a full history with multidi...
ORL.ro, 2019
One of the most commonly used modern terms for the generic evaluation of human existence is the q... more One of the most commonly used modern terms for the generic evaluation of human existence is the quality of life. According to the definition of the World Health Organization, this is the individuals’ perception of their own social status, in the context of the social value systems they adhere to, while also being co-dependent on their own necessities, standards and aspirations. This complex approach entails, besides the perception of their own body, the understanding of the surrounding environment in which we live our lives. Their utility consists in assuring the best possible correlation and adaptation between these two benchmarks. The acknowledgement of these indispensable components is mainly accomplished through the sensory organs. The majority of the classic sensory organs and some of the ones that were later correlated with man’s capacity of modern integration into his ecosystem belong to the field of ENT. Thus, it is only natural that, besides the aesthetic concern...