Huri GÜVEY - Academia.edu (original) (raw)
Papers by Huri GÜVEY
Curēus, Apr 4, 2024
Background and objectives: Prior studies have shown conflicting results on the impact of maternal... more Background and objectives: Prior studies have shown conflicting results on the impact of maternal anxiety on breastfeeding initiation and success. Furthermore, a substantial increase in maternal anxiety levels was shown in response to the COVID-19 pandemic. In this study, we aimed to investigate the relationship between maternal perinatal anxiety induced by the COVID-19 pandemic and early breastfeeding outcomes. Materials and methods: This cross-sectional study was conducted in two regional maternity hospitals, involving 220 first-time pregnant patients with a gestational age of ≥37 weeks. All patients had no current diagnosis of COVID-19 and no cases of COVID-19 in their close environment at the time of admission. At 24-48 hours postpartum or at the time of discharge, three following scoring systems were employed: the Coronavirus Anxiety Scale (CAS), the State-Trait Anxiety Inventory (STAI), and the LATCH (short for latch, audible swallowing, type of nipple, comfort, and hold) score. A LATCH score of ≥8 was chosen as the cutoff point for defining successful breastfeeding performance. Spearman's rank correlation was used to evaluate relationships between the CAS, STAI scores, maternal and infant factors, and LATCH scores. Results: There were no differences in baseline characteristics between groups categorized as successful and unsuccessful in breastfeeding initiation. The mean total STAI score was 86.3±13.2, the CAS score was 1.07±1.91, and the LATCH score was 8.42±1.7. Although there was an increase in State-Trait Anxiety Inventory-State Anxiety (STAI-S) scores compared to State-Trait Anxiety Inventory-Trait Anxiety (STAI-T) scores, and the STAI-S score and CAS score were higher in the unsuccessful group, these differences did not reach statistical significance (p = 0.22 and 0.16, respectively). When we evaluated the correlation of the LATCH score with STAI total, STAI-S and STAI-T scores, CAS score, and maternal and infant factors, only the type of delivery showed a significant correlation with the LATCH score (p = 0.008). Conclusions: Early postpartum breastfeeding efficiency, as measured by the LATCH score, was only correlated with the type of delivery. No significant correlation was found between pandemic-related maternal perinatal anxiety and early postpartum breastfeeding success.
New trends in medicine sciences, May 21, 2024
European Journal of Human Health, 2021
Objective: A twin pregnancy with associated complete hydatidiform mole is a rare clinical entity ... more Objective: A twin pregnancy with associated complete hydatidiform mole is a rare clinical entity which may present in different severe antenatal complications. The aim of this study is to present a case of twinning of a 37 weeks fetus and coexistent complete mole complicated with severe preeclampsia and emergency C-section with a healthy live born fetus. Case Report: A 32 year old G2 P1 pregnant woman who admitted at the perinatal center of maternity hospital was diagnosed a molar pregnancy coexisting with a healthy growing fetus at 10th weeks of gestation. At 32 weeks of gestation, preeclampsia was developed, the patient was followed until 37 weeks gestation when the clinical status of her turned into severe preeclampsia and cesarean section was carried out with the birth of a healthy fetus. Conclusions: Twinning with a coexistent complete hydatidiform mole may cause life-threatening complications for both fetus and the mother. Severe preeclampsia may be triggered in patients with coexisting molar pregnancy and such patients are recommended to be evaluated for molar pregnancy associating normal fetus that had a normal antenatal course in their previous pregnancies.
Ginekologia Polska
Objectives: Poor overall neonatal outcomes, small neonatal head circumference, neonatal hypoglyce... more Objectives: Poor overall neonatal outcomes, small neonatal head circumference, neonatal hypoglycemia, need for Neonatal Intensive Care Unit and late-onset neonatal sepsis are more common in adolescents. The aim of this study is to draw attention to the outcomes of adolescent pregnancies. Material and methods: This retrospective study was conducted in adolescent singleton pregnancies with maternal age < 15 years (n = 20, group 1), 16-19 years (n = 1929, group 2), and 20 years (n = 866, group 3). Age, gravidity, parity, and body mass index (BMI) measurements of mothers; mode of delivery, maternal and neonatal outcomes were evaluated and compared. Results: The rate of preterm birth, postpartum hemorrhage, asymmetrical intra-uterine growth restriction (IUGR, as 3% percentile), macrosomia, and height of newborn of Group 3 was significantly higher. The rate of asymmetrical IUGR (as 10% percentile) was significantly lower in Group 3. The rate of severe preeclampsia and cesarean section was significantly higher in Group 3. The rate of Small for Gestational Age newborn, neonatal hypoglycemia, and late-onset neonatal sepsis was significantly higher in Group 1. Conclusions: Neonatal problems with poor obstetric outcomes are common in adolescent pregnant women, so that a family planning and baby care social trainings are important in achieving good long-term maternal and neonatal outcomes.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
Experimental Neurology, 1999
Using a rat model, several laboratories have demonstrated long-term effects of Caesarean section ... more Using a rat model, several laboratories have demonstrated long-term effects of Caesarean section (Csection) birth or of global hypoxia during C-section birth on a variety of central nervous system (CNS) parameters. These studies used C-section delivery from rapidly decapitated dams, to avoid confounding anesthetic effects, or from dams anesthetized with halothane or ether under unspecified conditions. Systemic oxygenation or cerebral energy metabolites in the pups at birth have not been systematically measured in this model. To develop and characterize a C-section model with relevance to the human situation, the present study measured arterial/venous blood gases and pH and brain ATP and lactate, a widely accepted measure of CNS hypoxia, in pups born either vaginally, by C-section from decapitated dams, or by C-section from dams anesthetized with nitrous oxide (N 2 O) and increasing concentrations of isoflurane under welldefined conditions. Immediately after birth, pups born vaginally, by C-section with maternal decapitation, or by C-section with 2.5% isoflurane showed no group differences in systemic pO 2 or pH or brain ATP levels, but pCO 2 was elevated in the C-section/2.5% isoflurane group. Pups born by C-section with 3.0, 3.5, or 4.0% isoflurane, showed progressive reductions in blood pO 2 and increases in pCO 2 and blood pH was reduced with 3.5% isoflurane. Relative to vaginal birth, brain lactate levels were unchanged in pups born by Csection with any concentration (2.5-4.0%) of isoflurane, but reduced in pups born by C-section from decapitated dams. At 1 h (and 4 h) after birth, in both vaginally born controls and the 2.5% isoflurane group, brain lactate fell while blood pO 2 and brain ATP remained stable. In the 3.0, 3.5, or 4.0% isoflurane groups, blood gases and pH and brain lactate also normalized to control values. In conclusion, rat neonates show minimal signs of systemic or CNS hypoxia following C-section birth under 2.5% isoflurane with N 2 O. However, there is a rather narrow window of isoflurane concentrations which produces effective maternal anesthesia without producing respiratory compromise in the neonate. Thus the results indicate that the level of maternal anesthesia employed is an important factor influencing neonatal systemic and CNS oxygenation during C-section birth. 1999 Academic Press
Düzce Tıp Fakültesi Dergisi
Aim: The aim of this study was to determine the effect of paternal age on miscarriage rates in co... more Aim: The aim of this study was to determine the effect of paternal age on miscarriage rates in couples undergoing in vitro fertilization/intracytoplasmic sperm injection treatment cycles. Material and Methods: Patients were classified into two groups. The study group consisted of the patients whose pregnancy resulted in a miscarriage (n=73) and a control group in which the patients had a live singleton birth (n=256). Demographic characteristics, treatment indications, duration of infertility, menstruation day 3 follicle stimulating hormone, estradiol, luteinizing hormone, total antral follicle count, anti-Mullerian hormone levels and controlled ovarian stimulation parameters, day of trigger, estradiol and progesterone levels on the day of trigger, the total number of oocytes retrieved, the number of mature oocytes, the number and quality of the embryo, endometrial thickness on the day of trigger, oocyte pick up and embryo transfer, the distance of embryo-fundus and the day of embryo...
Hiperemezis gravidarum (HG), inatçı bulantı kusmayla seyreden, maternal morbidite ve mortaliteye ... more Hiperemezis gravidarum (HG), inatçı bulantı kusmayla seyreden, maternal morbidite ve mortaliteye neden olabilen etiyolojisi tam olarak ortaya konulamamış bir durumdur. Hastalığın etiyolojisinde enflamatuar süreçlerin yer aldığı düşünülmektedir. Biz de çalışmamızda HG tanısı alan ve sağlıklı gebelerde enflamatuar belirteçler olan beyaz küre sayısı (BK), monosit/lenfosit oranı (MLR), C-reaktif protein (CRP) ve ferritin düzeylerini değerlendirmeyi amaçladık.
Düzce Tıp Fakültesi Dergisi
Aim: This study was conducted to explore the effect of serum anti-Mullerian hormone (AMH) level o... more Aim: This study was conducted to explore the effect of serum anti-Mullerian hormone (AMH) level on in vitro fertilization (IVF) cycle outcomes. Material and Methods: A total of 142 patients included in this study, were divided into three groups according to their serum AMH levels as Group 1: AMH level 5-10 ng/ml (n=108), Group 2: AMH level 10-15 ng/ml (n=20), and Group 3: AMH level >15 ng/ml (n=14). Demographic characteristics were recorded. The duration of infertility and stimulation, the number of cycles, initial, final, and total doses of gonadotropins, and estradiol (E2) and progesterone levels on the day of trigger, oocyte pick up (OPU) and embryo transfer (ET), the total number of oocytes retrieved, the number of mature oocytes, the number and quality of the embryo, and also endometrial thickness on the day of trigger, OPU and ET, the distance of embryo-fundus, the day of ET, and pregnancy outcomes were all recorded. Results: While the IVF treatment indications and pregnanc...
Journal of Experimental and Clinical Medicine
Coronavirus Disease-19 (COVID-19) pandemic, affected pregnant women as well as many people. Aim o... more Coronavirus Disease-19 (COVID-19) pandemic, affected pregnant women as well as many people. Aim of this study is to compare complete blood count (CBC) parameters of pregnant women infected with COVID-19 to that of healthy pregnant women and determine their prognostic features. 142 pregnant women infected with COVID-19 and 46 healthy pregnant women, included in this retrospective case-control study. Patients infected with COVID-19 were grouped as mild, moderate and severe, according to the findings of oxygen saturation and lung involvement. Age, gestational age, gravida, hospitalization length and CBC parameters of the participants were compared, according to the groups. CBC test revealed that uninfected pregnant women had statistically lower level of white blood cell count (WBC, p=0.001), platelet count (p=0,024), neutrophil count (p=0,001), lymphocytes (p=0,005), monocytes (p=0,001) and platelecrit (p=0.007) than from infected pregnant women. Evaluation of pregnant women with COVID...
Journal of Experimental and Clinical Medicine
Vitamin D is an essential molecule for reproductive health. There are studies in the literature s... more Vitamin D is an essential molecule for reproductive health. There are studies in the literature showing contradictory results regarding te relationship between serum 25(OH) vitamin D levels and ovarian reserve markers. The aim of this retrospective cohort study was to investigate the relationship between ovarian reserve markers; follicle stimulating hormone (FSH), antral follicle count (AFC), and anti-Müllerian hormone (AMH), and serum 25(OH) vitamin D levels. 195 infertil women aged between 18-45 years were included in the study. After the participants were divided into 2 groups according to their 25 (OH) D levels (those with < 20ng/ml (vitamin D deficiency) and those with ≥ 20ng/ml (vitamin D insufficiency)), the age, body mass index (BMI), AFC, AMH, FSH levels of the groups were compared. The mean age of the 25(OH) vitamin D deficient group was significantly younger (p=0.025) than the other group. There was no statistically significant difference in BMI (p=0.47) or season of b...
Journal of Turkish Society of Obstetric and Gynecology
Erken başlangıçlı ve ağır preeklampsi ile serum kaderin 6 ve 11 seviyeleri arasındaki ilişki: Bir... more Erken başlangıçlı ve ağır preeklampsi ile serum kaderin 6 ve 11 seviyeleri arasındaki ilişki: Bir pilot çalışma
Dismenore adölesanlarda ve genç kadınlarda en sık görülen jinekolojikproblemlerden biridir. Genel... more Dismenore adölesanlarda ve genç kadınlarda en sık görülen jinekolojikproblemlerden biridir. Genellikle primer ve sekonder olmak üzere iki tiptekategorize edilir. Primer dismenore mens döneminde ortaya çıkan tanımlanabilen herhangi bir pelvik patoloji olmadan rekürren, kramp şeklindeortaya çıkan karın ağrılarıdır. Prevalansı %8,8 den %94 e kadar değişkenlik göstermektedir. Birçok çalışma şiddetli menstüel ağrının iş veyaokuldan uzak kalmaya ve günlük aktivitelerde kısıtlanmaya yol açtığınıgöstermektedir. Patofizyolojiye endometriumdaki prostaglandin ve lökotrien yolaklarındaki aktivite ve uterin kontraksiyonlardaki artışın katkıdabulunduğu çalışmalarda belirtilmektedir. Erken menarş, uzun menstrüelperiyotlar, yoğun menstrüel kanama, sigara kullanma ve aile öyküsü primer dismenorenin risk faktörleri arasında bulunmaktadır. Dismenoreyleilişkili ağrını şiddetini derecelendirmede çok boyutlu ağrı skorlama sistemi ve görsel analog skala kullanılmaktadır. Ancak bunlar hastanın kendiifadesi...
Kafkas Journal of Medical Sciences
Ege Klinikleri Tıp Dergisi, 2020
Sakarya Medical Journal, 2022
International Journal of Environmental Research and Public Health, 2022
The objective of this study was to assess the value of serum leptin, adiponectin, apelin, and ghr... more The objective of this study was to assess the value of serum leptin, adiponectin, apelin, and ghrelin as biomarkers for the prediction and diagnosis of intra-hepatic cholestasis (ICP). This prospective study included pregnant women in the third trimester of pregnancy: 63 with ICP, 48 and 15 of whom had mild and severe disease, respectively, and 32 as controls. ICP women had increased median levels of serum leptin, adiponectin, apelin, and ghrelin compared to the controls (p < 0.05). These biomarkers meaningfully changed regarding the severity of ICP: While leptin was reduced, apelin and ghrelin were increased, and adiponectin was increased somewhat. To predict and diagnose ICP, the predictive values of serum leptin, adiponectin, and apelin need to be accepted as comparable, with moderate to high sensitivity and specificity; however, the predictive value of serum ghrelin was somewhat lower. More research is needed to clarify the potential properties of adipokines to gain acceptanc...
Curēus, Apr 4, 2024
Background and objectives: Prior studies have shown conflicting results on the impact of maternal... more Background and objectives: Prior studies have shown conflicting results on the impact of maternal anxiety on breastfeeding initiation and success. Furthermore, a substantial increase in maternal anxiety levels was shown in response to the COVID-19 pandemic. In this study, we aimed to investigate the relationship between maternal perinatal anxiety induced by the COVID-19 pandemic and early breastfeeding outcomes. Materials and methods: This cross-sectional study was conducted in two regional maternity hospitals, involving 220 first-time pregnant patients with a gestational age of ≥37 weeks. All patients had no current diagnosis of COVID-19 and no cases of COVID-19 in their close environment at the time of admission. At 24-48 hours postpartum or at the time of discharge, three following scoring systems were employed: the Coronavirus Anxiety Scale (CAS), the State-Trait Anxiety Inventory (STAI), and the LATCH (short for latch, audible swallowing, type of nipple, comfort, and hold) score. A LATCH score of ≥8 was chosen as the cutoff point for defining successful breastfeeding performance. Spearman's rank correlation was used to evaluate relationships between the CAS, STAI scores, maternal and infant factors, and LATCH scores. Results: There were no differences in baseline characteristics between groups categorized as successful and unsuccessful in breastfeeding initiation. The mean total STAI score was 86.3±13.2, the CAS score was 1.07±1.91, and the LATCH score was 8.42±1.7. Although there was an increase in State-Trait Anxiety Inventory-State Anxiety (STAI-S) scores compared to State-Trait Anxiety Inventory-Trait Anxiety (STAI-T) scores, and the STAI-S score and CAS score were higher in the unsuccessful group, these differences did not reach statistical significance (p = 0.22 and 0.16, respectively). When we evaluated the correlation of the LATCH score with STAI total, STAI-S and STAI-T scores, CAS score, and maternal and infant factors, only the type of delivery showed a significant correlation with the LATCH score (p = 0.008). Conclusions: Early postpartum breastfeeding efficiency, as measured by the LATCH score, was only correlated with the type of delivery. No significant correlation was found between pandemic-related maternal perinatal anxiety and early postpartum breastfeeding success.
New trends in medicine sciences, May 21, 2024
European Journal of Human Health, 2021
Objective: A twin pregnancy with associated complete hydatidiform mole is a rare clinical entity ... more Objective: A twin pregnancy with associated complete hydatidiform mole is a rare clinical entity which may present in different severe antenatal complications. The aim of this study is to present a case of twinning of a 37 weeks fetus and coexistent complete mole complicated with severe preeclampsia and emergency C-section with a healthy live born fetus. Case Report: A 32 year old G2 P1 pregnant woman who admitted at the perinatal center of maternity hospital was diagnosed a molar pregnancy coexisting with a healthy growing fetus at 10th weeks of gestation. At 32 weeks of gestation, preeclampsia was developed, the patient was followed until 37 weeks gestation when the clinical status of her turned into severe preeclampsia and cesarean section was carried out with the birth of a healthy fetus. Conclusions: Twinning with a coexistent complete hydatidiform mole may cause life-threatening complications for both fetus and the mother. Severe preeclampsia may be triggered in patients with coexisting molar pregnancy and such patients are recommended to be evaluated for molar pregnancy associating normal fetus that had a normal antenatal course in their previous pregnancies.
Ginekologia Polska
Objectives: Poor overall neonatal outcomes, small neonatal head circumference, neonatal hypoglyce... more Objectives: Poor overall neonatal outcomes, small neonatal head circumference, neonatal hypoglycemia, need for Neonatal Intensive Care Unit and late-onset neonatal sepsis are more common in adolescents. The aim of this study is to draw attention to the outcomes of adolescent pregnancies. Material and methods: This retrospective study was conducted in adolescent singleton pregnancies with maternal age < 15 years (n = 20, group 1), 16-19 years (n = 1929, group 2), and 20 years (n = 866, group 3). Age, gravidity, parity, and body mass index (BMI) measurements of mothers; mode of delivery, maternal and neonatal outcomes were evaluated and compared. Results: The rate of preterm birth, postpartum hemorrhage, asymmetrical intra-uterine growth restriction (IUGR, as 3% percentile), macrosomia, and height of newborn of Group 3 was significantly higher. The rate of asymmetrical IUGR (as 10% percentile) was significantly lower in Group 3. The rate of severe preeclampsia and cesarean section was significantly higher in Group 3. The rate of Small for Gestational Age newborn, neonatal hypoglycemia, and late-onset neonatal sepsis was significantly higher in Group 1. Conclusions: Neonatal problems with poor obstetric outcomes are common in adolescent pregnant women, so that a family planning and baby care social trainings are important in achieving good long-term maternal and neonatal outcomes.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
Experimental Neurology, 1999
Using a rat model, several laboratories have demonstrated long-term effects of Caesarean section ... more Using a rat model, several laboratories have demonstrated long-term effects of Caesarean section (Csection) birth or of global hypoxia during C-section birth on a variety of central nervous system (CNS) parameters. These studies used C-section delivery from rapidly decapitated dams, to avoid confounding anesthetic effects, or from dams anesthetized with halothane or ether under unspecified conditions. Systemic oxygenation or cerebral energy metabolites in the pups at birth have not been systematically measured in this model. To develop and characterize a C-section model with relevance to the human situation, the present study measured arterial/venous blood gases and pH and brain ATP and lactate, a widely accepted measure of CNS hypoxia, in pups born either vaginally, by C-section from decapitated dams, or by C-section from dams anesthetized with nitrous oxide (N 2 O) and increasing concentrations of isoflurane under welldefined conditions. Immediately after birth, pups born vaginally, by C-section with maternal decapitation, or by C-section with 2.5% isoflurane showed no group differences in systemic pO 2 or pH or brain ATP levels, but pCO 2 was elevated in the C-section/2.5% isoflurane group. Pups born by C-section with 3.0, 3.5, or 4.0% isoflurane, showed progressive reductions in blood pO 2 and increases in pCO 2 and blood pH was reduced with 3.5% isoflurane. Relative to vaginal birth, brain lactate levels were unchanged in pups born by Csection with any concentration (2.5-4.0%) of isoflurane, but reduced in pups born by C-section from decapitated dams. At 1 h (and 4 h) after birth, in both vaginally born controls and the 2.5% isoflurane group, brain lactate fell while blood pO 2 and brain ATP remained stable. In the 3.0, 3.5, or 4.0% isoflurane groups, blood gases and pH and brain lactate also normalized to control values. In conclusion, rat neonates show minimal signs of systemic or CNS hypoxia following C-section birth under 2.5% isoflurane with N 2 O. However, there is a rather narrow window of isoflurane concentrations which produces effective maternal anesthesia without producing respiratory compromise in the neonate. Thus the results indicate that the level of maternal anesthesia employed is an important factor influencing neonatal systemic and CNS oxygenation during C-section birth. 1999 Academic Press
Düzce Tıp Fakültesi Dergisi
Aim: The aim of this study was to determine the effect of paternal age on miscarriage rates in co... more Aim: The aim of this study was to determine the effect of paternal age on miscarriage rates in couples undergoing in vitro fertilization/intracytoplasmic sperm injection treatment cycles. Material and Methods: Patients were classified into two groups. The study group consisted of the patients whose pregnancy resulted in a miscarriage (n=73) and a control group in which the patients had a live singleton birth (n=256). Demographic characteristics, treatment indications, duration of infertility, menstruation day 3 follicle stimulating hormone, estradiol, luteinizing hormone, total antral follicle count, anti-Mullerian hormone levels and controlled ovarian stimulation parameters, day of trigger, estradiol and progesterone levels on the day of trigger, the total number of oocytes retrieved, the number of mature oocytes, the number and quality of the embryo, endometrial thickness on the day of trigger, oocyte pick up and embryo transfer, the distance of embryo-fundus and the day of embryo...
Hiperemezis gravidarum (HG), inatçı bulantı kusmayla seyreden, maternal morbidite ve mortaliteye ... more Hiperemezis gravidarum (HG), inatçı bulantı kusmayla seyreden, maternal morbidite ve mortaliteye neden olabilen etiyolojisi tam olarak ortaya konulamamış bir durumdur. Hastalığın etiyolojisinde enflamatuar süreçlerin yer aldığı düşünülmektedir. Biz de çalışmamızda HG tanısı alan ve sağlıklı gebelerde enflamatuar belirteçler olan beyaz küre sayısı (BK), monosit/lenfosit oranı (MLR), C-reaktif protein (CRP) ve ferritin düzeylerini değerlendirmeyi amaçladık.
Düzce Tıp Fakültesi Dergisi
Aim: This study was conducted to explore the effect of serum anti-Mullerian hormone (AMH) level o... more Aim: This study was conducted to explore the effect of serum anti-Mullerian hormone (AMH) level on in vitro fertilization (IVF) cycle outcomes. Material and Methods: A total of 142 patients included in this study, were divided into three groups according to their serum AMH levels as Group 1: AMH level 5-10 ng/ml (n=108), Group 2: AMH level 10-15 ng/ml (n=20), and Group 3: AMH level >15 ng/ml (n=14). Demographic characteristics were recorded. The duration of infertility and stimulation, the number of cycles, initial, final, and total doses of gonadotropins, and estradiol (E2) and progesterone levels on the day of trigger, oocyte pick up (OPU) and embryo transfer (ET), the total number of oocytes retrieved, the number of mature oocytes, the number and quality of the embryo, and also endometrial thickness on the day of trigger, OPU and ET, the distance of embryo-fundus, the day of ET, and pregnancy outcomes were all recorded. Results: While the IVF treatment indications and pregnanc...
Journal of Experimental and Clinical Medicine
Coronavirus Disease-19 (COVID-19) pandemic, affected pregnant women as well as many people. Aim o... more Coronavirus Disease-19 (COVID-19) pandemic, affected pregnant women as well as many people. Aim of this study is to compare complete blood count (CBC) parameters of pregnant women infected with COVID-19 to that of healthy pregnant women and determine their prognostic features. 142 pregnant women infected with COVID-19 and 46 healthy pregnant women, included in this retrospective case-control study. Patients infected with COVID-19 were grouped as mild, moderate and severe, according to the findings of oxygen saturation and lung involvement. Age, gestational age, gravida, hospitalization length and CBC parameters of the participants were compared, according to the groups. CBC test revealed that uninfected pregnant women had statistically lower level of white blood cell count (WBC, p=0.001), platelet count (p=0,024), neutrophil count (p=0,001), lymphocytes (p=0,005), monocytes (p=0,001) and platelecrit (p=0.007) than from infected pregnant women. Evaluation of pregnant women with COVID...
Journal of Experimental and Clinical Medicine
Vitamin D is an essential molecule for reproductive health. There are studies in the literature s... more Vitamin D is an essential molecule for reproductive health. There are studies in the literature showing contradictory results regarding te relationship between serum 25(OH) vitamin D levels and ovarian reserve markers. The aim of this retrospective cohort study was to investigate the relationship between ovarian reserve markers; follicle stimulating hormone (FSH), antral follicle count (AFC), and anti-Müllerian hormone (AMH), and serum 25(OH) vitamin D levels. 195 infertil women aged between 18-45 years were included in the study. After the participants were divided into 2 groups according to their 25 (OH) D levels (those with < 20ng/ml (vitamin D deficiency) and those with ≥ 20ng/ml (vitamin D insufficiency)), the age, body mass index (BMI), AFC, AMH, FSH levels of the groups were compared. The mean age of the 25(OH) vitamin D deficient group was significantly younger (p=0.025) than the other group. There was no statistically significant difference in BMI (p=0.47) or season of b...
Journal of Turkish Society of Obstetric and Gynecology
Erken başlangıçlı ve ağır preeklampsi ile serum kaderin 6 ve 11 seviyeleri arasındaki ilişki: Bir... more Erken başlangıçlı ve ağır preeklampsi ile serum kaderin 6 ve 11 seviyeleri arasındaki ilişki: Bir pilot çalışma
Dismenore adölesanlarda ve genç kadınlarda en sık görülen jinekolojikproblemlerden biridir. Genel... more Dismenore adölesanlarda ve genç kadınlarda en sık görülen jinekolojikproblemlerden biridir. Genellikle primer ve sekonder olmak üzere iki tiptekategorize edilir. Primer dismenore mens döneminde ortaya çıkan tanımlanabilen herhangi bir pelvik patoloji olmadan rekürren, kramp şeklindeortaya çıkan karın ağrılarıdır. Prevalansı %8,8 den %94 e kadar değişkenlik göstermektedir. Birçok çalışma şiddetli menstüel ağrının iş veyaokuldan uzak kalmaya ve günlük aktivitelerde kısıtlanmaya yol açtığınıgöstermektedir. Patofizyolojiye endometriumdaki prostaglandin ve lökotrien yolaklarındaki aktivite ve uterin kontraksiyonlardaki artışın katkıdabulunduğu çalışmalarda belirtilmektedir. Erken menarş, uzun menstrüelperiyotlar, yoğun menstrüel kanama, sigara kullanma ve aile öyküsü primer dismenorenin risk faktörleri arasında bulunmaktadır. Dismenoreyleilişkili ağrını şiddetini derecelendirmede çok boyutlu ağrı skorlama sistemi ve görsel analog skala kullanılmaktadır. Ancak bunlar hastanın kendiifadesi...
Kafkas Journal of Medical Sciences
Ege Klinikleri Tıp Dergisi, 2020
Sakarya Medical Journal, 2022
International Journal of Environmental Research and Public Health, 2022
The objective of this study was to assess the value of serum leptin, adiponectin, apelin, and ghr... more The objective of this study was to assess the value of serum leptin, adiponectin, apelin, and ghrelin as biomarkers for the prediction and diagnosis of intra-hepatic cholestasis (ICP). This prospective study included pregnant women in the third trimester of pregnancy: 63 with ICP, 48 and 15 of whom had mild and severe disease, respectively, and 32 as controls. ICP women had increased median levels of serum leptin, adiponectin, apelin, and ghrelin compared to the controls (p < 0.05). These biomarkers meaningfully changed regarding the severity of ICP: While leptin was reduced, apelin and ghrelin were increased, and adiponectin was increased somewhat. To predict and diagnose ICP, the predictive values of serum leptin, adiponectin, and apelin need to be accepted as comparable, with moderate to high sensitivity and specificity; however, the predictive value of serum ghrelin was somewhat lower. More research is needed to clarify the potential properties of adipokines to gain acceptanc...