Ivo Lušić - Academia.edu (original) (raw)
Papers by Ivo Lušić
Collegium Antropologicum, Jun 1, 2007
The aim of this study was to determine the incidence of monosymptomatic optic neuritis (MON) and ... more The aim of this study was to determine the incidence of monosymptomatic optic neuritis (MON) and progression of MON to multiple sclerosis (MS) from the Mediterranean region of southern Europe in the County of Split-Dalmatia, Croatia during the 11 years period from 1991 to 2001. This study was made retrospectively on the 87 cases (59 female, aged 25.9±11.3 and 28 male aged 29.9±9.2
PubMed, Mar 1, 2012
Multiple sclerosis (MS) is a chronic demyelinating neurologic disorder that mainly affects young ... more Multiple sclerosis (MS) is a chronic demyelinating neurologic disorder that mainly affects young individuals (aged 20 to 50 years). Approximately 85% of patients experience an initial course with relapses and remissions (relapsing-remitting multiple sclerosis). Guidelines for the management of MS should be focused on three main areas: (a) the diagnosis of MS; (b) treatment of relapses; and (c) long-term preventive treatment including clinical follow up, dose adjustment, drug switch, control of therapeutic efficacy, and disease progression. Diagnosis should be established according to clinical and paraclinical criteria. Discussion on therapeutic recommendations is focused on the disease-modifying agents in acute phases and drugs for long-term treatment and symptomatic treatment. Differential diagnoses must be taken into account on making the diagnosis of MS. Therefore, diagnosis of MS should be established on clinical and radiological diagnostic criteria, cerebrospinal fluid analysis and evoked potentials.
Znanstveni pristup dijagnostici i terapiji glavobolja, 2005
Anali Opce bolnice u Splitu, 1981
Neurologica Croatica, 2005
Neurologija za medicinare, 2009
Medix : specijalizirani medicinski dvomjesečnik, Jun 15, 2014
Zbornik radova 2. kongres neurologa Bosne i Hercegovine s međunarodnim sudjelovanjem, 2006
Odabrana poglavlja iz akutne medicine, 2005
Brosura daje odgovore na najcesca pitanja koja se postavljaju lijecniku o epilepsiji: sto je epil... more Brosura daje odgovore na najcesca pitanja koja se postavljaju lijecniku o epilepsiji: sto je epilepsija, kako izgleda epilepticki napadaj, koji su uzroci epilepsije, je li epilepsija nasljedna, može li epilepsija biti uzrokovana drugim bolestima, sto je to aura, koji sve tipovi epileptickih napadaja postoje, sto je elektroencefalografija, kako se dijagnosticira i lijeci epilepsija, sto su antiepileptici i koje su njihove nuspojave, je li epilepsija izljeciva bolest itd. Ilustrativnim crtežima i tablicama prikazana je i prva pomoc pri epileptickome napadaju. Brosura sadrži i savjete kako živjeti s epilepsijom.
The Journal of Headache and Pain, 2021
Background New treatments are currently offering new opportunities and challenges in clinical man... more Background New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. To overcome those issues, the European Headache Federation (EHF) issued a Consensus document to propose criteria to approach difficult-to-treat migraine patients in a standardized way. The Consensus proposed well-defined criteria for resistant migraine (i.e., patients who do not respond to some treatment but who have residual therapeutic opportunities) and refractory migraine (i.e., patients who still have debilitating migraine despite maximal treatment efforts). The aim of this study was to better understand the perceived impact of resistant and refractory migraine and the attitude of physicians involved in migraine care toward those conditions. Methods We conducted a web-questionnair...
Revista de Neurología, 1999
INTRODUCTION AND METHOD A retrospective study was made of the incidence of stroke in the Dalmatia... more INTRODUCTION AND METHOD A retrospective study was made of the incidence of stroke in the Dalmatian region (Split) during the war in the Republic of Croatia (1991-1995), to determine whether the war had affected the incidence of stroke in the population at risk. The data obtained was compared with data regarding the incidence of strokes in the pre-war period (1986-1990). RESULTS AND CONCLUSIONS There was a small but significant increase in the incidence of strokes during the war period. There was also a considerable increase in patients with primary intracerebral hemorrhage during this period. The possible causes of this increase in patients with primary intracerebral hemorrhage are discussed.
Concussion, 2018
Aim: The objective of this study was to administer and analyze results of a survey targeting know... more Aim: The objective of this study was to administer and analyze results of a survey targeting knowledge about concussion symptoms, diagnosis, treatment and expected recovery among family medicine specialists in the Split–Dalmatia County of Croatia. Methods: An electronic survey questionnaire was developed utilizing concepts from previously published studies on concussion knowledge, attitudes and beliefs completed by physicians. The survey was intended to briefly and broadly assess concussion knowledge of Croatian healthcare providers. The first section of the survey included five questions clarifying professional practice, years of experience and experience with concussions; the second section included 15 questions about typical concussion symptoms; the third section included 12 questions focused upon three primary components of concussion knowledge: concussion diagnosis, treatment and recovery. Results: Out of 242 surveys mailed, 81 questionnaires (33%) were completed while 161 resp...
Bratislavské lekárske listy, 2009
While reviewing the available literature, we noticed comorbidity of epilepsy and psychiatric diso... more While reviewing the available literature, we noticed comorbidity of epilepsy and psychiatric disorders. Psychiatric disorders were observed more frequently in patients with high seizure frequency. There is significant prevalence of epilepsy comorbidity with depression, anxiety disorders, and to a lesser extent with bipolar disorders and other forms of psychosis. Suicidal risk factors, ideation and attempts in these patients as correlates of depression or as psychopathological features were associated to epileptic disease. This is confirmed by additional burden of epilepsy patients with psychic disorders (Ref. 70). Full Text (Free, PDF) www.bmj.sk.
Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti, 2008
Introducing serotonin 5-HT1B/1D agonists in the migraine treatment in the early 1990s had for the... more Introducing serotonin 5-HT1B/1D agonists in the migraine treatment in the early 1990s had for the first time set guidelines for targeting a hypothetic physiologic source of the sequence of events in migraine, and results thus achieved were considerably better than those accomplished with earlier nonselective pharmacological approach. Triptans have revolutionized migraine management and inspired many epidemiological and public health surveys, strengthened efforts in understanding pathophysiology of migraine and initiated synthesis of many similar drugs in the triptan group, the first being sumatriptan. Triptans have risen to a therapeutic challenge posed by migraine, successfully thwarting the cycle of pain. In treating migraine sufferers, physicians can choose among seven triptans with different attributes. Each patient merits individualized approach in the treatment of migraine with triptans. Choosing the right triptan for a given patient is a matter of first matching the appropria...
Bratislavské lekárske listy, 2008
Results achieved in treating the Parkinson's disease (PD) by the dopamine receptor agonist, r... more Results achieved in treating the Parkinson's disease (PD) by the dopamine receptor agonist, ropinirole, have been hampered by its side effects. According to the MEDLINE, the most common side effects of ropinirole are extreme sleepiness and/or sudden sleep attacks, nausea, dyspepsia, vertigo, orthostatic hypotension and leg oedema. The prospective research included PD patients who were administered non-ergoline dopamine agonist, ropinirole, over this period of time. The control group of patients were treated with levodopa. The research included 50 patients: 31 women and 19 men, of the mean age of 61.4 +/- 4.3 years. One patient reported sleepiness and one of them sudden sleep attacks. Nausea was experienced by three patients, and vertigo by two. Depression, orthostatic hypotension, leg oedema, dyspepsia, dry cough and hypersalivation were registered in particular cases. The control group of PD patients, treated with levodopa, comprised 52 patients, 33 women and 19 men of the mean...
Collegium antropologicum, 2001
Migraine is one of the most prevalent types of headache, which imposes a substantial burden on so... more Migraine is one of the most prevalent types of headache, which imposes a substantial burden on society as measured by direct and indirect costs. In the present work we review the obstacles to carrying out migraine epidemiological studies. Knowledge of the epidemiology of migraine has expanded because of the recent proliferation of large scale population-based studies using standardized case definitions. Previous surveys of the prevalence of migraine have given widely differing results. Even in population-based studies, there have been wide variations in estimates of migraine prevalence. The development of International Headache Society (IHS) criteria for migraine has facilitated international comparisons in epidemiologic studies by providing explicit and consistent diagnostic criteria, Recent studies using IHS diagnostic criteria have given relatively consistent estimates of migraine prevalence (about 15-18% of women and 6% of men). Studies of racial diversity in the prevalence of m...
Collegium Antropologicum, Jun 1, 2007
The aim of this study was to determine the incidence of monosymptomatic optic neuritis (MON) and ... more The aim of this study was to determine the incidence of monosymptomatic optic neuritis (MON) and progression of MON to multiple sclerosis (MS) from the Mediterranean region of southern Europe in the County of Split-Dalmatia, Croatia during the 11 years period from 1991 to 2001. This study was made retrospectively on the 87 cases (59 female, aged 25.9±11.3 and 28 male aged 29.9±9.2
PubMed, Mar 1, 2012
Multiple sclerosis (MS) is a chronic demyelinating neurologic disorder that mainly affects young ... more Multiple sclerosis (MS) is a chronic demyelinating neurologic disorder that mainly affects young individuals (aged 20 to 50 years). Approximately 85% of patients experience an initial course with relapses and remissions (relapsing-remitting multiple sclerosis). Guidelines for the management of MS should be focused on three main areas: (a) the diagnosis of MS; (b) treatment of relapses; and (c) long-term preventive treatment including clinical follow up, dose adjustment, drug switch, control of therapeutic efficacy, and disease progression. Diagnosis should be established according to clinical and paraclinical criteria. Discussion on therapeutic recommendations is focused on the disease-modifying agents in acute phases and drugs for long-term treatment and symptomatic treatment. Differential diagnoses must be taken into account on making the diagnosis of MS. Therefore, diagnosis of MS should be established on clinical and radiological diagnostic criteria, cerebrospinal fluid analysis and evoked potentials.
Znanstveni pristup dijagnostici i terapiji glavobolja, 2005
Anali Opce bolnice u Splitu, 1981
Neurologica Croatica, 2005
Neurologija za medicinare, 2009
Medix : specijalizirani medicinski dvomjesečnik, Jun 15, 2014
Zbornik radova 2. kongres neurologa Bosne i Hercegovine s međunarodnim sudjelovanjem, 2006
Odabrana poglavlja iz akutne medicine, 2005
Brosura daje odgovore na najcesca pitanja koja se postavljaju lijecniku o epilepsiji: sto je epil... more Brosura daje odgovore na najcesca pitanja koja se postavljaju lijecniku o epilepsiji: sto je epilepsija, kako izgleda epilepticki napadaj, koji su uzroci epilepsije, je li epilepsija nasljedna, može li epilepsija biti uzrokovana drugim bolestima, sto je to aura, koji sve tipovi epileptickih napadaja postoje, sto je elektroencefalografija, kako se dijagnosticira i lijeci epilepsija, sto su antiepileptici i koje su njihove nuspojave, je li epilepsija izljeciva bolest itd. Ilustrativnim crtežima i tablicama prikazana je i prva pomoc pri epileptickome napadaju. Brosura sadrži i savjete kako živjeti s epilepsijom.
The Journal of Headache and Pain, 2021
Background New treatments are currently offering new opportunities and challenges in clinical man... more Background New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. To overcome those issues, the European Headache Federation (EHF) issued a Consensus document to propose criteria to approach difficult-to-treat migraine patients in a standardized way. The Consensus proposed well-defined criteria for resistant migraine (i.e., patients who do not respond to some treatment but who have residual therapeutic opportunities) and refractory migraine (i.e., patients who still have debilitating migraine despite maximal treatment efforts). The aim of this study was to better understand the perceived impact of resistant and refractory migraine and the attitude of physicians involved in migraine care toward those conditions. Methods We conducted a web-questionnair...
Revista de Neurología, 1999
INTRODUCTION AND METHOD A retrospective study was made of the incidence of stroke in the Dalmatia... more INTRODUCTION AND METHOD A retrospective study was made of the incidence of stroke in the Dalmatian region (Split) during the war in the Republic of Croatia (1991-1995), to determine whether the war had affected the incidence of stroke in the population at risk. The data obtained was compared with data regarding the incidence of strokes in the pre-war period (1986-1990). RESULTS AND CONCLUSIONS There was a small but significant increase in the incidence of strokes during the war period. There was also a considerable increase in patients with primary intracerebral hemorrhage during this period. The possible causes of this increase in patients with primary intracerebral hemorrhage are discussed.
Concussion, 2018
Aim: The objective of this study was to administer and analyze results of a survey targeting know... more Aim: The objective of this study was to administer and analyze results of a survey targeting knowledge about concussion symptoms, diagnosis, treatment and expected recovery among family medicine specialists in the Split–Dalmatia County of Croatia. Methods: An electronic survey questionnaire was developed utilizing concepts from previously published studies on concussion knowledge, attitudes and beliefs completed by physicians. The survey was intended to briefly and broadly assess concussion knowledge of Croatian healthcare providers. The first section of the survey included five questions clarifying professional practice, years of experience and experience with concussions; the second section included 15 questions about typical concussion symptoms; the third section included 12 questions focused upon three primary components of concussion knowledge: concussion diagnosis, treatment and recovery. Results: Out of 242 surveys mailed, 81 questionnaires (33%) were completed while 161 resp...
Bratislavské lekárske listy, 2009
While reviewing the available literature, we noticed comorbidity of epilepsy and psychiatric diso... more While reviewing the available literature, we noticed comorbidity of epilepsy and psychiatric disorders. Psychiatric disorders were observed more frequently in patients with high seizure frequency. There is significant prevalence of epilepsy comorbidity with depression, anxiety disorders, and to a lesser extent with bipolar disorders and other forms of psychosis. Suicidal risk factors, ideation and attempts in these patients as correlates of depression or as psychopathological features were associated to epileptic disease. This is confirmed by additional burden of epilepsy patients with psychic disorders (Ref. 70). Full Text (Free, PDF) www.bmj.sk.
Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti, 2008
Introducing serotonin 5-HT1B/1D agonists in the migraine treatment in the early 1990s had for the... more Introducing serotonin 5-HT1B/1D agonists in the migraine treatment in the early 1990s had for the first time set guidelines for targeting a hypothetic physiologic source of the sequence of events in migraine, and results thus achieved were considerably better than those accomplished with earlier nonselective pharmacological approach. Triptans have revolutionized migraine management and inspired many epidemiological and public health surveys, strengthened efforts in understanding pathophysiology of migraine and initiated synthesis of many similar drugs in the triptan group, the first being sumatriptan. Triptans have risen to a therapeutic challenge posed by migraine, successfully thwarting the cycle of pain. In treating migraine sufferers, physicians can choose among seven triptans with different attributes. Each patient merits individualized approach in the treatment of migraine with triptans. Choosing the right triptan for a given patient is a matter of first matching the appropria...
Bratislavské lekárske listy, 2008
Results achieved in treating the Parkinson's disease (PD) by the dopamine receptor agonist, r... more Results achieved in treating the Parkinson's disease (PD) by the dopamine receptor agonist, ropinirole, have been hampered by its side effects. According to the MEDLINE, the most common side effects of ropinirole are extreme sleepiness and/or sudden sleep attacks, nausea, dyspepsia, vertigo, orthostatic hypotension and leg oedema. The prospective research included PD patients who were administered non-ergoline dopamine agonist, ropinirole, over this period of time. The control group of patients were treated with levodopa. The research included 50 patients: 31 women and 19 men, of the mean age of 61.4 +/- 4.3 years. One patient reported sleepiness and one of them sudden sleep attacks. Nausea was experienced by three patients, and vertigo by two. Depression, orthostatic hypotension, leg oedema, dyspepsia, dry cough and hypersalivation were registered in particular cases. The control group of PD patients, treated with levodopa, comprised 52 patients, 33 women and 19 men of the mean...
Collegium antropologicum, 2001
Migraine is one of the most prevalent types of headache, which imposes a substantial burden on so... more Migraine is one of the most prevalent types of headache, which imposes a substantial burden on society as measured by direct and indirect costs. In the present work we review the obstacles to carrying out migraine epidemiological studies. Knowledge of the epidemiology of migraine has expanded because of the recent proliferation of large scale population-based studies using standardized case definitions. Previous surveys of the prevalence of migraine have given widely differing results. Even in population-based studies, there have been wide variations in estimates of migraine prevalence. The development of International Headache Society (IHS) criteria for migraine has facilitated international comparisons in epidemiologic studies by providing explicit and consistent diagnostic criteria, Recent studies using IHS diagnostic criteria have given relatively consistent estimates of migraine prevalence (about 15-18% of women and 6% of men). Studies of racial diversity in the prevalence of m...