Ian Tsang - Academia.edu (original) (raw)
Papers by Ian Tsang
The Journal of rheumatology, 2003
OBJECTIVE To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy... more OBJECTIVE To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheumatoid arthritis (RA). METHODS A 6 week randomized double blind placebo controlled study of 61 patients with RA meeting American College of Rheumatology (ACR) criteria was conducted in China. The primary outcome was a modified ACR-20 response rate, analyzed by logistic regression analysis. RESULTS The modified ACR-20 response rate differed significantly (topical TW 58% vs placebo 20%; p = 0.002). There was an 8.1-fold (95% CI 1.9-35.4) increase in the modified ACR-20 response for the TW compared to the placebo group, adjusted for age and erythrocyte sedimentation rate. CONCLUSION Topical TW appears efficacious for the treatment of RA, but larger studies are needed.
Cmaj Canadian Medical Association Journal, Apr 17, 2001
Canadian family physician Médecin de famille canadien, 1990
Osteoarthritis is the most common type of arthritis affecting humans. Its clinical features are w... more Osteoarthritis is the most common type of arthritis affecting humans. Its clinical features are well recognized, and its diagnosis is easily established. The etiopathogenesis of the disease is still poorly understood. The definition and classification of osteoarthritis have only recently been set up by the American Rheumatism Association and the National Institutes of Health-sponsored workshop. Management should be four-fold: educational, physiatric, medical, and surgical. The management goal should be individualized and be aimed at symptomatic relief and restoration of function.
Nature Clinical Practice Rheumatology, 2007
Chinese Journal of Integrative Medicine, 2013
The Journal of Rheumatology, 2010
Chinese Journal of Integrative Medicine, 2013
Arthritis & Rheumatism, 1977
Cmaj Canadian Medical Association Journal Journal De L Association Medicale Canadienne, Apr 17, 2001
Orthopedic Clinics of North America
We believe that investigations into back pain and spinal changes in microgravity will contribute ... more We believe that investigations into back pain and spinal changes in microgravity will contribute significantly to our knowledge and understanding of factors that cause back pain and the influence of spinal cord distraction on sensory and autonomic dysfunction. This information may have clinical implications for the treatment and rehabilitation of patients with spinal cord injury, for the care of patients during and after corrective spinal surgery, for the care and treatment of patients with chronic pain syndromes, and may potentially provide us with the opportunity to learn more about demyelinating diseases.
Journal of biological photography
2009 2nd International Conference on Biomedical Engineering and Informatics, 2009
... [8] Dimitrios Spentzos, Douglas A. Levine, Shakirahmed Kolia, Hasan Otu, Jeff Boyd, Towia A. ... more ... [8] Dimitrios Spentzos, Douglas A. Levine, Shakirahmed Kolia, Hasan Otu, Jeff Boyd, Towia A. Libermann, Stephen ... 2000; 902:17-24. [10] Holly K. Dressman, Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, Jennifer Clarke, Regina S. Whitaker ...
The Journal of rheumatology, 2003
To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheum... more To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheumatoid arthritis (RA). A 6 week randomized double blind placebo controlled study of 61 patients with RA meeting American College of Rheumatology (ACR) criteria was conducted in China. The primary outcome was a modified ACR-20 response rate, analyzed by logistic regression analysis. The modified ACR-20 response rate differed significantly (topical TW 58% vs placebo 20%; p = 0.002). There was an 8.1-fold (95% CI 1.9-35.4) increase in the modified ACR-20 response for the TW compared to the placebo group, adjusted for age and erythrocyte sedimentation rate. Topical TW appears efficacious for the treatment of RA, but larger studies are needed.
Spine, 1992
The diurnal height change reported to occur in young adults was investigated to characterize chan... more The diurnal height change reported to occur in young adults was investigated to characterize changes in the lumbar range of motion, spinal profile, and range of motion of the back. Twelve subjects aged 18-22 years were measured using stereophotography and standard clinical examinations in the evening and after a minimum of 8 hours of complete bed rest. The average increase in height was 20 mm. Forty percent of the height increase took place in the lumbar spine without change in the depth of the lordosis, and forty percent took place in the thoracic curve with a decrease in the kyphosis. The remaining 20% of the height increase was not located, but no measurements were taken of the cervical spine. Range of motion studies revealed that lumbar flexion, as measured using the lumbar flexion increment, was decreased in the morning, and straight leg raise was decreased when measured clinically but not when measured photographically. Extension, rotation, and femoral stretch test were not affected. The authors conclude that stereophotogrammetry offers an accurate, noninvasive way to study spinal profiles. Further work is needed to assess and quantify the relative motion of the skin and the underlying structures.
The American Journal of Chinese Medicine, 2008
The predictive roles of symptom combination traditionally evaluated in traditional Chinese medici... more The predictive roles of symptom combination traditionally evaluated in traditional Chinese medicine (TCM) in the treatment of rheumatoid arthritis (RA) were explored. Three hundred and ninety six patients were randomly divided into 197 subjects receiving Western medicine therapy (WM) and 199 subjects receiving TCM therapy (TCM). A complete physical examination and 18 clinical manifestations typically assessed in TCM were recorded before the randomization. The ACR responses were used for efficacy evaluation. ACR20 and 50 responses with WM treatment were higher than in the TCM group. The 18 symptoms in RA could be clustered into 4 symptom combinations with factor analysis, which represent joint symptoms, cold pattern, deficiency pattern and hot pattern in TCM respectively. TCM would be more effective in patients with weak-symptom combination 3 (deficiency pattern in TCM), and WM would be more effective in patients with symptom combination 2 (cold pattern in TCM). Symptom combinations judged with TCM may have influence on the efficacy of therapy in the treatment of RA.
Current Opinion in Rheumatology, 1993
Low back pain is a common and expensive ailment among the working population. Despite the increas... more Low back pain is a common and expensive ailment among the working population. Despite the increasing amount of basic and clinical knowledge on low back pain, the precise causes of almost all cases cannot yet be defined. The tissues that could be the sources of pain in the low back have been better identified. The validity of the commonly used diagnosis of facet syndrome is now being questioned, and a favorable response to injection of the facet joints should not be considered an indication for posterior lumbar fusion. Studies continue to indicate that total body vibration and cigarette smoking have a relationship to disk degeneration. Improved imaging techniques such as computed tomography and magnetic resonance imaging allow better visualization of the pathology in the vertebral column, but the correlation between these imaging findings and clinical symptoms has yet to be proven. Psychosocial factors are now recognized as important in patients with low back pain. Surgical procedures, even when appropriately indicated, have produced no better result than has the natural course of the condition.
Complementary Therapies in Medicine, 2008
The Journal of Rheumatology, 2010
The Journal of rheumatology, 2003
OBJECTIVE To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy... more OBJECTIVE To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheumatoid arthritis (RA). METHODS A 6 week randomized double blind placebo controlled study of 61 patients with RA meeting American College of Rheumatology (ACR) criteria was conducted in China. The primary outcome was a modified ACR-20 response rate, analyzed by logistic regression analysis. RESULTS The modified ACR-20 response rate differed significantly (topical TW 58% vs placebo 20%; p = 0.002). There was an 8.1-fold (95% CI 1.9-35.4) increase in the modified ACR-20 response for the TW compared to the placebo group, adjusted for age and erythrocyte sedimentation rate. CONCLUSION Topical TW appears efficacious for the treatment of RA, but larger studies are needed.
Cmaj Canadian Medical Association Journal, Apr 17, 2001
Canadian family physician Médecin de famille canadien, 1990
Osteoarthritis is the most common type of arthritis affecting humans. Its clinical features are w... more Osteoarthritis is the most common type of arthritis affecting humans. Its clinical features are well recognized, and its diagnosis is easily established. The etiopathogenesis of the disease is still poorly understood. The definition and classification of osteoarthritis have only recently been set up by the American Rheumatism Association and the National Institutes of Health-sponsored workshop. Management should be four-fold: educational, physiatric, medical, and surgical. The management goal should be individualized and be aimed at symptomatic relief and restoration of function.
Nature Clinical Practice Rheumatology, 2007
Chinese Journal of Integrative Medicine, 2013
The Journal of Rheumatology, 2010
Chinese Journal of Integrative Medicine, 2013
Arthritis & Rheumatism, 1977
Cmaj Canadian Medical Association Journal Journal De L Association Medicale Canadienne, Apr 17, 2001
Orthopedic Clinics of North America
We believe that investigations into back pain and spinal changes in microgravity will contribute ... more We believe that investigations into back pain and spinal changes in microgravity will contribute significantly to our knowledge and understanding of factors that cause back pain and the influence of spinal cord distraction on sensory and autonomic dysfunction. This information may have clinical implications for the treatment and rehabilitation of patients with spinal cord injury, for the care of patients during and after corrective spinal surgery, for the care and treatment of patients with chronic pain syndromes, and may potentially provide us with the opportunity to learn more about demyelinating diseases.
Journal of biological photography
2009 2nd International Conference on Biomedical Engineering and Informatics, 2009
... [8] Dimitrios Spentzos, Douglas A. Levine, Shakirahmed Kolia, Hasan Otu, Jeff Boyd, Towia A. ... more ... [8] Dimitrios Spentzos, Douglas A. Levine, Shakirahmed Kolia, Hasan Otu, Jeff Boyd, Towia A. Libermann, Stephen ... 2000; 902:17-24. [10] Holly K. Dressman, Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, Jennifer Clarke, Regina S. Whitaker ...
The Journal of rheumatology, 2003
To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheum... more To assess the efficacy of topical Tripterygium wilfordii (TW), a Chinese herbal therapy, in rheumatoid arthritis (RA). A 6 week randomized double blind placebo controlled study of 61 patients with RA meeting American College of Rheumatology (ACR) criteria was conducted in China. The primary outcome was a modified ACR-20 response rate, analyzed by logistic regression analysis. The modified ACR-20 response rate differed significantly (topical TW 58% vs placebo 20%; p = 0.002). There was an 8.1-fold (95% CI 1.9-35.4) increase in the modified ACR-20 response for the TW compared to the placebo group, adjusted for age and erythrocyte sedimentation rate. Topical TW appears efficacious for the treatment of RA, but larger studies are needed.
Spine, 1992
The diurnal height change reported to occur in young adults was investigated to characterize chan... more The diurnal height change reported to occur in young adults was investigated to characterize changes in the lumbar range of motion, spinal profile, and range of motion of the back. Twelve subjects aged 18-22 years were measured using stereophotography and standard clinical examinations in the evening and after a minimum of 8 hours of complete bed rest. The average increase in height was 20 mm. Forty percent of the height increase took place in the lumbar spine without change in the depth of the lordosis, and forty percent took place in the thoracic curve with a decrease in the kyphosis. The remaining 20% of the height increase was not located, but no measurements were taken of the cervical spine. Range of motion studies revealed that lumbar flexion, as measured using the lumbar flexion increment, was decreased in the morning, and straight leg raise was decreased when measured clinically but not when measured photographically. Extension, rotation, and femoral stretch test were not affected. The authors conclude that stereophotogrammetry offers an accurate, noninvasive way to study spinal profiles. Further work is needed to assess and quantify the relative motion of the skin and the underlying structures.
The American Journal of Chinese Medicine, 2008
The predictive roles of symptom combination traditionally evaluated in traditional Chinese medici... more The predictive roles of symptom combination traditionally evaluated in traditional Chinese medicine (TCM) in the treatment of rheumatoid arthritis (RA) were explored. Three hundred and ninety six patients were randomly divided into 197 subjects receiving Western medicine therapy (WM) and 199 subjects receiving TCM therapy (TCM). A complete physical examination and 18 clinical manifestations typically assessed in TCM were recorded before the randomization. The ACR responses were used for efficacy evaluation. ACR20 and 50 responses with WM treatment were higher than in the TCM group. The 18 symptoms in RA could be clustered into 4 symptom combinations with factor analysis, which represent joint symptoms, cold pattern, deficiency pattern and hot pattern in TCM respectively. TCM would be more effective in patients with weak-symptom combination 3 (deficiency pattern in TCM), and WM would be more effective in patients with symptom combination 2 (cold pattern in TCM). Symptom combinations judged with TCM may have influence on the efficacy of therapy in the treatment of RA.
Current Opinion in Rheumatology, 1993
Low back pain is a common and expensive ailment among the working population. Despite the increas... more Low back pain is a common and expensive ailment among the working population. Despite the increasing amount of basic and clinical knowledge on low back pain, the precise causes of almost all cases cannot yet be defined. The tissues that could be the sources of pain in the low back have been better identified. The validity of the commonly used diagnosis of facet syndrome is now being questioned, and a favorable response to injection of the facet joints should not be considered an indication for posterior lumbar fusion. Studies continue to indicate that total body vibration and cigarette smoking have a relationship to disk degeneration. Improved imaging techniques such as computed tomography and magnetic resonance imaging allow better visualization of the pathology in the vertebral column, but the correlation between these imaging findings and clinical symptoms has yet to be proven. Psychosocial factors are now recognized as important in patients with low back pain. Surgical procedures, even when appropriately indicated, have produced no better result than has the natural course of the condition.
Complementary Therapies in Medicine, 2008
The Journal of Rheumatology, 2010