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Papers by Igor Illarramendi

International Ophthalmology

$Research paper thumbnail of Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction$

Eye, 2017

The aim of this study was to gain greater insight into the corneal densitometry changes occurring... more The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE). Patients and methods Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre-and postoperative corneal densitometry was measured using an Oculus Pentacam system. Results The mean postoperative total corneal densitometry values were 16.53 ± 1.94 for the LASIK-FS group, 15.53 ± 1.65 for PRK, and 16.10 ± 1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0-2, 2-6, and 6-10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (Po0.05), but these variations across techniques were not statistically significant. Conclusions Corneal densitometry can be used as an objective metric to assess corneal response to refractive surgery, and to monitor patients over time. Corneal densitometry was not negatively affected by any of the refractive surgical procedures under evaluation.

$Research paper thumbnail of Influence of angle kappa on visual and refractive outcomes after implantation of a diffractive trifocal intraocular lens$

Journal of Cataract and Refractive Surgery

$Research paper thumbnail of Corneal densitometry and its correlation with age, pachymetry, corneal curvature, and refraction$

International Ophthalmology, 2016

To determine normative corneal densitometry values in relation to age, sex, refractive error, cor... more To determine normative corneal densitometry values in relation to age, sex, refractive error, corneal thickness, and keratometry, measured using the Oculus Pentacam system. Three hundred and thirty-eight healthy subjects (185 men; 153 women) with no corneal disease underwent an exhaustive ocular examination. Corneal densitometry was expressed in standardized grayscale units (GSU). The mean corneal densitometry over the total area was 16.46 ± 1.85 GSU. The Pearson correlation coefficient for total densitometry was r = 0.542 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). Statistically significant differences were found between men and women for the total area (p = 0.006), with readings of 16.22 ± 1.54 GSU and 16.60 ± 1.83 GSU, respectively. When the cornea was divided into layers of different depths, a significant correlation was found for all layers and age: r = 0.447 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001), r = 0.563 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001), and r = 0.520 (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001) for the anterior, central, and posterior layers, respectively. However, when the cornea was divided into concentric annuli starting from the center of the cornea, densitometry was strongly correlated only with age in the 6-10-mm annulus (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). Neither mean keratometry nor spherical equivalent was correlated with corneal densitometry in any zone of the cornea (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 0.05). This is the first report of normative corneal densitometry values in relation to keratometry, corneal thickness, and spherical equivalent measured with the latest Oculus Pentacam software. Corneal densitometry increases with age, but corneal keratometry and refractive parameters do not affect light scattering in the human cornea.

Journal of Cataract & Refractive Surgery, 2012

To assess the repeatability, reproducibility, and agreement of the Pentacam HR singlecamera and G... more To assess the repeatability, reproducibility, and agreement of the Pentacam HR singlecamera and Galilei G2 dual-camera Scheimpflug devices in anterior segment analysis. SETTING: Begitek Cl ınica Oftalmol ogica, San Sebasti an, Spain. DESIGN: Prospective randomized observational study. METHODS: Healthy young individuals had 3 consecutive tests by 2 examiners. Analyzed parameters were anterior and posterior cornea simulated keratometry (K), K flat, K steep, astigmatism magnitude and axis, J 0 and J 45 vectors, asphericity, total corneal higher-order wavefront aberrations (root mean square [RMS], coma, trefoil, spherical aberration), central cornea and thinnest-point thicknesses, and anterior chamber depth. Repeatability and reproducibility were evaluated by calculating the within-subject standard deviation (S w), some derived coefficients, and the intraclass correlation coefficient. Agreement was assessed with the Bland-Altman method. RESULTS: The single-camera device reproducibility (S w) was simulated K, 0.04 diopter (D); J 0 , 0.03 D; J 45 , 0.04 D; total power, 0.04 D; spherical aberration, 0.02 mm; higher-order aberrations (HOAs), 0.02 mm; central corneal thickness (CCT), 3.39 mm. The dual-camera device S w was simulated K, 0.07 D; J 0 , 0.13 D; J 45 , 0.04 D; total power, 0.08 D; spherical aberration, 0.02 mm; HOAs, 0.11 mm; CCT, 1.36 mm. Agreement was good for most parameters except total corneal power (mean difference 1.58 D G 0.22 (SD) and HOA RMS (mean difference 0.48 G 0.19 mm) (both P<.00). CONCLUSIONS: Repeatability and reproducibility were good for all parameters. The single-camera device was more precise for curvature, astigmatism, and corneal wavefront error measurements and the dual-camera device for pachymetry measurements. Agreement was good with some relevant exceptions.

Journal of Cataract & …, 2009

Forty eyes (40 patients) were evaluated. In the toric group, 95% of eyes achieved 20/40 or better... more Forty eyes (40 patients) were evaluated. In the toric group, 95% of eyes achieved 20/40 or better UCVA and 70%, 20/25 or better. In the OCCI group, 80% of eyes achieved 20/40 or better UCVA and 50%, 20/25 or better. All eyes achieved 20/25 or better BCVA. Mean refractive ...