N. J . Inyang - Academia.edu (original) (raw)

Papers by N. J . Inyang

The Internet Journal of Microbiology, 2008

This study outlined how pneumococcal pneumonia complicated the clinical presentations of pulmonar... more This study outlined how pneumococcal pneumonia complicated the clinical presentations of pulmonary tuberculosis and showed the predictive value of Pseudomembranous candidiasis (PC) in detection of unknown Human immunodeficiency virus (HIV) infection in Ekpoma. Out of 510 sputum samples analyzed, bacteria and fungi were identified using standard microbiological methods and sera of 240 patients, with undiagnosed PC, whose sputum had Candida albicans, were screened for HIV. Exactly 44.1% were co-infected with Streptococcus pneumoniae and Mycobacterium tuberculosis while 40.2% had M. tuberculosis and C. albicans. Out of 260 patients clinically diagnosed with pulmonary tuberculosis, 23.1% had Streptococcus pneumoniae, while 69.3% of 150 patients clinically diagnosed with pneumonia had M. tuberculosis. Exactly 79.2% of 240 patients with PC, had undetected HIV. Pneumococcal pneumonia complicated the clinical diagnosis of pulmonary tuberculosis. PC was 79.2% predictive of undiagnosed HIV infection. Full laboratory investigation remains invaluable in the management of mixed infections.

This investigation determined the effect of different concentrations of Acridine Orange (AO) on s... more This investigation determined the effect of different concentrations of Acridine Orange (AO) on selected Gram positive and Gram negative organisms. Twenty (20) clinical isolates of multidrug-resistant strains that included Staphylococcus aureus (5;25%), Escherichia coli (6;30%) Pseudomonas aeruginosa (5;25%) and Klebsiella species (4;20%), were obtained from the Department of Medical Microbiology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria. The differences in drug susceptibility profiles of the isolates before and after AO-curing, were evaluated and compared. In comparison, Staphylococcus aureus strains 1, 2 & 4; E.coli strain 1; P. aeruginosa strain 1&4, and Klebsiella species strains 1&3 showed statistically significant differences (P<0.05) in curing rates unlike Staphylococcus aureus strain 3 and E. coli strains 5&6 (P>0.05). E. coli strains 2&5, P. aeruginosa strains 2&3, and Klebsiella species strain 4, showed sensitivity to a minimum of one antibiotic ...

Seven isolates of Streptococcus pneumoniae were isolated from sputum samples of suspected tubercu... more Seven isolates of Streptococcus pneumoniae were isolated from sputum samples of suspected tuberculosis patients and characterized. KirbyBauer disc diffusion technique was adopted in susceptibility testing of isolates. Isolates showed the highest resistance of 85.7% to norfloxacin and ampicillin –cloxacillin, while the lowest resistance of 14. 3% was to caftaxidime and pefloxacin. The difference in resistance observed between norfloxacin and pefloxacine discourages a common practice where one antibiotic is used for susceptibility test and another (from the same group) is used for treatment. S. pneumoniae is significantly resistant to most of the commonly available antibiotics in Ekpoma and its environs.

Nigerian journal of clinical practice, 2010

A comparative study of intradermal smear in the diagnosis of malaria in symptomatic pregnant wome... more A comparative study of intradermal smear in the diagnosis of malaria in symptomatic pregnant women. Venous blood served as the control. Fifty consecutive symptomatic pregnant women were recruited. Thick films of both venous and intradermal blood were examined. Questionnaires were used to determine patients' preference for the two techniques. Tests of statistical significance were done with Fisher exact and Yates correlation coefficient at 95% confidence interval. Sensitivity specificity and accuracy rates were used to assess the validity of intradermal smear. Intradermal smear more frequently diagnosed malaria parasitaemia than peripheral venous blood (66% vs 56%). This was statistically significant (P value: 0.0065). The sensitivity of intradermal smear was 85.7% while the positive predictive value was 77.4%. The accuracy rate was 76.7%. The technique of intradermal blood collection was preferred by 28% of women. Intradermal smear is useful in malaria diagnosis in pregnancy and...

The Nigerian postgraduate medical journal, 2009

We evaluated the usefulness of intradermal smear microscopy (IDS) in the detection of asymptomati... more We evaluated the usefulness of intradermal smear microscopy (IDS) in the detection of asymptomatic malaria parasitaemia in pregnancy. Peripheral venous blood (PVB) served as control. The preference for the collection technique of dermal blood was also assessed. One hundred and fifty (150) asymptomatic women were recruited. They had both intradermal smear and peripheral venous blood smear were made for all patients. Measures of test validity included sensitivity, specificity and accuracy rate. Test of statistical significance was with Yates correlation at 95% confidence limit. The prevalence of asymptomatic malaria parasitaemia was higher using intradermal smear (35.3% vs 33.3%) though this was not statistically significant. Intradermal smear had a sensitivity of 40% and specificity of 67%. The positive predictive value was 37.8% with accuracy rate of 58%. 41% of participants preferred the technique of collection of intradermal blood. Intradermal smear appears to have no usefulness i...

Brazilian Journal of Microbiology, 2009

This survey was designed to determine the prevalence of Plasmodium falciparum and Salmonella Typh... more This survey was designed to determine the prevalence of Plasmodium falciparum and Salmonella Typhi among febrile HIV/AIDS patients in Ekpoma. Malaria and typhoid risk factors in Ekpoma included occupation, poor health facilities and poor sanitation. Malaria and typhoid are highly prevalent among Ekpoma HIV/AIDS patients.

The survey carried out on the prevalence of dental caries among individuals in Ekpoma and its env... more The survey carried out on the prevalence of dental caries among individuals in Ekpoma and its environs
revealed that Streptococcus mutans was the most prevalent cariogenic organism causing dental caries in
the environment. A prevalence of S. mutans (72%), S. salivarius (14%) and Lactobacillus acidophilus
(10%) was recorded. The dental caries was observed in different age groups although sex of the
individuals did not play any significant role in the rate of bacterial isolation. Good oral hygiene and
public enlightenment programmes are advocated.

The Internet Journal of Microbiology, 2008

This study outlined how pneumococcal pneumonia complicated the clinical presentations of pulmonar... more This study outlined how pneumococcal pneumonia complicated the clinical presentations of pulmonary tuberculosis and showed the predictive value of Pseudomembranous candidiasis (PC) in detection of unknown Human immunodeficiency virus (HIV) infection in Ekpoma. Out of 510 sputum samples analyzed, bacteria and fungi were identified using standard microbiological methods and sera of 240 patients, with undiagnosed PC, whose sputum had Candida albicans, were screened for HIV. Exactly 44.1% were co-infected with Streptococcus pneumoniae and Mycobacterium tuberculosis while 40.2% had M. tuberculosis and C. albicans. Out of 260 patients clinically diagnosed with pulmonary tuberculosis, 23.1% had Streptococcus pneumoniae, while 69.3% of 150 patients clinically diagnosed with pneumonia had M. tuberculosis. Exactly 79.2% of 240 patients with PC, had undetected HIV. Pneumococcal pneumonia complicated the clinical diagnosis of pulmonary tuberculosis. PC was 79.2% predictive of undiagnosed HIV infection. Full laboratory investigation remains invaluable in the management of mixed infections.

This investigation determined the effect of different concentrations of Acridine Orange (AO) on s... more This investigation determined the effect of different concentrations of Acridine Orange (AO) on selected Gram positive and Gram negative organisms. Twenty (20) clinical isolates of multidrug-resistant strains that included Staphylococcus aureus (5;25%), Escherichia coli (6;30%) Pseudomonas aeruginosa (5;25%) and Klebsiella species (4;20%), were obtained from the Department of Medical Microbiology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria. The differences in drug susceptibility profiles of the isolates before and after AO-curing, were evaluated and compared. In comparison, Staphylococcus aureus strains 1, 2 & 4; E.coli strain 1; P. aeruginosa strain 1&4, and Klebsiella species strains 1&3 showed statistically significant differences (P<0.05) in curing rates unlike Staphylococcus aureus strain 3 and E. coli strains 5&6 (P>0.05). E. coli strains 2&5, P. aeruginosa strains 2&3, and Klebsiella species strain 4, showed sensitivity to a minimum of one antibiotic ...

Seven isolates of Streptococcus pneumoniae were isolated from sputum samples of suspected tubercu... more Seven isolates of Streptococcus pneumoniae were isolated from sputum samples of suspected tuberculosis patients and characterized. KirbyBauer disc diffusion technique was adopted in susceptibility testing of isolates. Isolates showed the highest resistance of 85.7% to norfloxacin and ampicillin –cloxacillin, while the lowest resistance of 14. 3% was to caftaxidime and pefloxacin. The difference in resistance observed between norfloxacin and pefloxacine discourages a common practice where one antibiotic is used for susceptibility test and another (from the same group) is used for treatment. S. pneumoniae is significantly resistant to most of the commonly available antibiotics in Ekpoma and its environs.

Nigerian journal of clinical practice, 2010

A comparative study of intradermal smear in the diagnosis of malaria in symptomatic pregnant wome... more A comparative study of intradermal smear in the diagnosis of malaria in symptomatic pregnant women. Venous blood served as the control. Fifty consecutive symptomatic pregnant women were recruited. Thick films of both venous and intradermal blood were examined. Questionnaires were used to determine patients' preference for the two techniques. Tests of statistical significance were done with Fisher exact and Yates correlation coefficient at 95% confidence interval. Sensitivity specificity and accuracy rates were used to assess the validity of intradermal smear. Intradermal smear more frequently diagnosed malaria parasitaemia than peripheral venous blood (66% vs 56%). This was statistically significant (P value: 0.0065). The sensitivity of intradermal smear was 85.7% while the positive predictive value was 77.4%. The accuracy rate was 76.7%. The technique of intradermal blood collection was preferred by 28% of women. Intradermal smear is useful in malaria diagnosis in pregnancy and...

The Nigerian postgraduate medical journal, 2009

We evaluated the usefulness of intradermal smear microscopy (IDS) in the detection of asymptomati... more We evaluated the usefulness of intradermal smear microscopy (IDS) in the detection of asymptomatic malaria parasitaemia in pregnancy. Peripheral venous blood (PVB) served as control. The preference for the collection technique of dermal blood was also assessed. One hundred and fifty (150) asymptomatic women were recruited. They had both intradermal smear and peripheral venous blood smear were made for all patients. Measures of test validity included sensitivity, specificity and accuracy rate. Test of statistical significance was with Yates correlation at 95% confidence limit. The prevalence of asymptomatic malaria parasitaemia was higher using intradermal smear (35.3% vs 33.3%) though this was not statistically significant. Intradermal smear had a sensitivity of 40% and specificity of 67%. The positive predictive value was 37.8% with accuracy rate of 58%. 41% of participants preferred the technique of collection of intradermal blood. Intradermal smear appears to have no usefulness i...

Brazilian Journal of Microbiology, 2009

This survey was designed to determine the prevalence of Plasmodium falciparum and Salmonella Typh... more This survey was designed to determine the prevalence of Plasmodium falciparum and Salmonella Typhi among febrile HIV/AIDS patients in Ekpoma. Malaria and typhoid risk factors in Ekpoma included occupation, poor health facilities and poor sanitation. Malaria and typhoid are highly prevalent among Ekpoma HIV/AIDS patients.

The survey carried out on the prevalence of dental caries among individuals in Ekpoma and its env... more The survey carried out on the prevalence of dental caries among individuals in Ekpoma and its environs
revealed that Streptococcus mutans was the most prevalent cariogenic organism causing dental caries in
the environment. A prevalence of S. mutans (72%), S. salivarius (14%) and Lactobacillus acidophilus
(10%) was recorded. The dental caries was observed in different age groups although sex of the
individuals did not play any significant role in the rate of bacterial isolation. Good oral hygiene and
public enlightenment programmes are advocated.